Stapled α−helical peptide drug development: A potent dual inhibitor of MDM2 and MDMX for p53-dependent cancer therapy von Chang, Yong S, Graves, Bradford, Guerlavais, Vincent, Tovar, Christian, Packman, Kathryn, To, Kwong-Him, Olson, Karen A, Kesavan, Kamala, Gangurde, Pranoti, Mukherjee, Aditi, Baker, Theresa, Darlak, Krzysztof, Elkin, Carl, Filipovic, Zoran, Qureshi, Farooq Z, Cai, Hongliang, Berry, Pamela, Feyfant, Eric, Shi, Xiangguo E, Horstick, James, Annis, D Allen, Manning, Anthony M, Fotouhi, Nader, Nash, Huw, Vassilev, Lyubomir T, Sawyer, Tomi K

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M281, an Anti‐FcRn Antibody: Pharmacodynamics, Pharmacokinetics, and Safety Across the Full Range of IgG Reduction in a First‐in‐Human Study von Ling, Leona E., Hillson, Jan L., Tiessen, Renger G., Bosje, Tjerk, Iersel, Mattheus Paulus, Nix, Darrell J., Markowitz, Lynn, Cilfone, Nicholas A., Duffner, Jay, Streisand, James B., Manning, Anthony M., Arroyo, Santiago

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Controlled tetra-Fc sialylation of IVIg results in a drug candidate with consistent enhanced anti-inflammatory activity von Washburn, Nathaniel, Schwab, Inessa, Ortiz, Daniel, Bhatnagar, Naveen, Lansing, Jonathan C., Medeiros, Amy, Tyler, Steven, Mekala, Divya, Cochran, Edward, Sarvaiya, Hetal, Garofalo, Kevin, Meccariello, Robin, Meador, James W., Rutitzky, Laura, Schultes, Birgit C., Ling, Leona, Avery, William, Nimmerjahn, Falk, Manning, Anthony M., Kaundinya, Ganesh V., Bosques, Carlos J.

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Multiomic study of skin, peripheral blood, and serum: is serum proteome a reflection of disease process at the end-organ level in systemic sclerosis? von Farutin, Victor, Kurtagic, Elma, Pradines, Joël R, Capila, Ishan, Mayes, Maureen D, Wu, Minghua, Manning, Anthony M, Assassi, Shervin

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Enhancing reproducibility of gene expression analysis with known protein functional relationships: The concept of well-associated protein von Pradines, Joël R, Farutin, Victor, Cilfone, Nicholas A, Ghavami, Abouzar, Kurtagic, Elma, Guess, Jamey, Manning, Anthony M, Capila, Ishan

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Molecular profiling of rheumatoid arthritis patients reveals an association between innate and adaptive cell populations and response to anti-tumor necrosis factor von Farutin, Victor, Prod'homme, Thomas, McConnell, Kevin, Washburn, Nathaniel, Halvey, Patrick, Etzel, Carol J, Guess, Jamey, Duffner, Jay, Getchell, Kristen, Meccariello, Robin, Gutierrez, Bryan, Honan, Christopher, Zhao, Ganlin, Cilfone, Nicholas A, Gunay, Nur Sibel, Hillson, Jan L, DeLuca, David S, Saunders, Katherine C, Pappas, Dimitrios A, Greenberg, Jeffrey D, Kremer, Joel M, Manning, Anthony M, Ling, Leona E, Capila, Ishan

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Engineered IgG1-Fc Molecules Define Valency Control of Cell Surface Fcγ Receptor Inhibition and Activation in Endosomes von Bailey, Elizabeth M, Choudhury, Amit, Vuppula, Harika, Ortiz, Daniel F, Schaeck, John, Manning, Anthony M, Bosques, Carlos J, Hoppe, Adam D

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Inhibitory Fc-Gamma IIb Receptor Signaling Induced by Multivalent IgG-Fc Is Dependent on Sialylation von Beneduce, Christopher, Nguyen, Stephanie, Washburn, Nathaniel, Schaeck, John, Meccariello, Robin, Holte, Kimberly, Ortiz, Daniel, Manning, Anthony M., Bosques, Carlos J., Kurtagic, Elma

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Targeting JNK for therapeutic benefit: from junk to gold? von Manning, Anthony M., Davis, Roger J.

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Fc-Gamma Receptors: Attractive Targets for Autoimmune Drug Discovery Searching for Intelligent Therapeutic Designs von Bosques, Carlos J, Manning, Anthony M

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Characterization of Endogenous Human FcγRIII by Mass Spectrometry Reveals Site, Allele and Sequence Specific Glycosylation[S] von Washburn, Nathaniel, Meccariello, Robin, Duffner, Jay, Getchell, Kristen, Holte, Kimberly, Prod'homme, Thomas, Srinivasan, Karunya, Prenovitz, Robert, Lansing, Jonathan, Capila, Ishan, Kaundinya, Ganesh, Manning, Anthony M., Bosques, Carlos J.

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Variable blood processing procedures contribute to plasma proteomic variability von Halvey, Patrick, Farutin, Victor, Koppes, Laura, Gunay, Nur Sibel, Pappas, Dimitrios A, Manning, Anthony M, Capila, Ishan

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NF-κB as a primary regulator of the stress response von Mercurio, Frank, Manning, Anthony M

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Multiple signals converging on NF-κB von Mercurio, Frank, Manning, Anthony M

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SP600125, An Anthrapyrazolone Inhibitor of Jun N-Terminal Kinase von Bennett, Brydon L., Sasaki, Dennis T., Murray, Brion W., O'Leary, Eoin C., Sakata, Steve T., Xu, Weiming, Leisten, Jim C., Motiwala, Aparna, Pierce, Steve, Satoh, Yoshitaka, Bhagwat, Shripad S., Manning, Anthony M., Anderson, David W.

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c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis von Han, Z, Boyle, D L, Chang, L, Bennett, B, Karin, M, Yang, L, Manning, A M, Firestein, G S

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Circulating Markers of Inflammation Persist in Children and Adults With Giant Aneurysms After Kawasaki Disease von Lech, Miroslaw, Guess, Jamey, Duffner, Jay, Oyamada, Jun, Shimizu, Chisato, Hoshino, Shinsuke, Farutin, Victor, Bulik, Dorota A, Gutierrez, Bryan, Sarvaiya, Hetal, Kapoor, Bulbul, Koppes, Laura, Saldova, Radka, Stockmann, Henning, Albrecht, Simone, McManus, Ciara, Rudd, Pauline M, Kaundinya, Ganesh V, Manning, Anthony M, Bosques, Carlos J, Kahn, Andrew M, Daniels, Lori B, Gordon, John B, Tremoulet, Adriana H, Capila, Ishan, Gunay, Nur Sibel, Ling, Leona E, Burns, Jane C

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A Quantitative Microtiter Assay for Sialylated Glycoform Analyses Using Lectin Complexes von Srinivasan, Karunya, Roy, Sucharita, Washburn, Nathaniel, Sipsey, Sandra F., Meccariello, Robin, Meador, III, James W., Ling, Leona E., Manning, Anthony M., Kaundinya, Ganesh V.

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IκB Kinase (IKK)-Associated Protein 1, a Common Component of the Heterogeneous IKK Complex von Mercurio, Frank, Murray, Brion W., Shevchenko, Andrej, Bennett, Brydon L., Young, David B., Li, Jian Wu, Pascual, Gabriel, Motiwala, Aparna, Zhu, Hengyi, Mann, Matthias, Manning, Anthony M.

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The kinase activities of interleukin-1 receptor associated kinase (IRAK)-1 and 4 are redundant in the control of inflammatory cytokine expression in human cells von Song, Kyung W., Talamas, Francisco X., Suttmann, Rebecca T., Olson, Pam S., Barnett, Jim W., Lee, Simon W., Thompson, Kelly D., Jin, Sue, Hekmat-Nejad, Mohammad, Cai, Terrence Z., Manning, Anthony M., Hill, Ronald J., Wong, Brian R.

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