Regulatory B cells prevent and reverse allergic airway inflammation via FoxP3-positive T regulatory cells in a murine model von Amu, Sylvie, PhD, Saunders, Sean P., BSc, Kronenberg, Mitchell, PhD, Mangan, Niamh E., PhD, Atzberger, Ann, MSc, Fallon, Padraic G., PhD

Volltext

Characterization of the pathoimmunology of necrotizing enterocolitis reveals novel therapeutic opportunities von Cho, Steven X., Rudloff, Ina, Lao, Jason C., Pang, Merrin A., Goldberg, Rimma, Bui, Christine B., McLean, Catriona A., Stock, Magdalena, Klassert, Tilman E., Slevogt, Hortense, Mangan, Niamh E., Cheng, Wei, Fischer, Doris, Gfroerer, Stefan, Sandhu, Manjeet K., Ngo, Devi, Bujotzek, Alexander, Lariviere, Laurent, Schumacher, Felix, Tiefenthaler, Georg, Beker, Friederike, Collins, Clare, Kamlin, C. Omar F., König, Kai, Malhotra, Atul, Tan, Kenneth, Theda, Christiane, Veldman, Alex, Ellisdon, Andrew M., Whisstock, James C., Berger, Philip J., Nold-Petry, Claudia A., Nold, Marcel F.

Volltext

Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape von Bidwell, Bradley N, Slaney, Clare Y, Withana, Nimali P, Forster, Sam, Cao, Yuan, Loi, Sherene, Andrews, Daniel, Mikeska, Thomas, Mangan, Niamh E, Samarajiwa, Shamith A, de Weerd, Nicole A, Gould, Jodee, Argani, Pedram, Möller, Andreas, Smyth, Mark J, Anderson, Robin L, Hertzog, Paul J, Parker, Belinda S

Volltext

Suppression of TH2-type allergic reactions by helminth infection von Fallon, Padraic G., Mangan, Niamh E.

Volltext

The Hydroxylase Inhibitor Dimethyloxalylglycine Is Protective in a Murine Model of Colitis von Cummins, Eoin P, Seeballuck, Fergal, Keely, Stephen J, Mangan, Niamh E, Callanan, John J, Fallon, Padraic G, Taylor, Cormac T

Volltext

A homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming von Irvine, Alan D, Shiohama, Aiko, Sundberg, John P, Presland, Richard B, Kudoh, Jun, Campbell, Linda E, Callanan, John J, Kawasaki, Hiroshi, Shimizu, Nobuyoshi, Mangan, Niamh E, Saunders, Sean P, Fleckman, Philip, Sandilands, Aileen, Kubo, Akiharu, Amagai, Masayuki, McLean, W H Irwin, Fallon, Padraic G, Sasaki, Takashi

Volltext

Interleukin-1 receptor antagonist prevents murine bronchopulmonary dysplasia induced by perinatal inflammation and hyperoxia von Nold, Marcel F., Mangan, Niamh E., Rudioff, Ina, Cho, Steven X., Shariatian, Nikeh, Samarasinghe, Thilini D., Skuza, Elizabeth M., Pedersen, John, Veldman, Alex, Berger, Philip J., Nold-Petry, Claudia A.

Volltext

The Role of Ets2 Transcription Factor in the Induction of MicroRNA-155 (miR-155) by Lipopolysaccharide and Its Targeting by Interleukin-10 von Quinn, Susan R., Mangan, Niamh E., Caffrey, Brian E., Gantier, Michael P., Williams, Bryan R.G., Hertzog, Paul J., McCoy, Claire E., O'Neill, Luke A.J.

Volltext

Helminth Infection Protects Mice from Anaphylaxis via IL-10-Producing B Cells von Mangan, Niamh E, Fallon, Rosemary E, Smith, Philip, van Rooijen, Nico, McKenzie, Andrew N, Fallon, Padraic G

Volltext

Interferon-epsilon is a novel regulator of NK cell responses in the uterus von Mayall, Jemma R, Horvat, Jay C, Mangan, Niamh E, Chevalier, Anne, McCarthy, Huw, Hampsey, Daniel, Donovan, Chantal, Brown, Alexandra C, Matthews, Antony Y, de Weerd, Nicole A, de Geus, Eveline D, Starkey, Malcolm R, Kim, Richard Y, Daly, Katie, Goggins, Bridie J, Keely, Simon, Maltby, Steven, Baldwin, Rennay, Foster, Paul S, Boyle, Michael J, Tanwar, Pradeep S, Huntington, Nicholas D, Hertzog, Paul J, Hansbro, Philip M

Volltext

Helminth-Modified Pulmonary Immune Response Protects Mice from Allergen-Induced Airway Hyperresponsiveness von Mangan, Niamh E, van Rooijen, Nico, McKenzie, Andrew N. J, Fallon, Padraic G

Volltext

Spatiotemporal regulation of human IFN-ε and innate immunity in the female reproductive tract von Bourke, Nollaig M., Achilles, Sharon L., Huang, Stephanie U-Shane, Cumming, Helen E., Lim, San S., Papageorgiou, Irene, Gearing, Linden J., Chapman, Ross, Thakore, Suruchi, Mangan, Niamh E., Mesiano, Sam, Hertzog, Paul J.

Volltext

T1/ST2 expression on Th2 cells negatively regulates allergic pulmonary inflammation von Mangan, Niamh E., Dasvarma, Ayan, McKenzie, Andrew N. J., Fallon, Padraic G.

Volltext

Fetal inhibition of inflammation improves disease phenotypes in harlequin ichthyosis von Cottle, Denny L, Ursino, Gloria M A, Ip, Sally Chi Ieng, Jones, Lynelle K, Ditommaso, Tia, Hacking, Douglas F, Mangan, Niamh E, Mellett, Natalie A, Henley, Katya J, Sviridov, Dmitri, Nold-Petry, Claudia A, Nold, Marcel F, Meikle, Peter J, Kile, Benjamin T, Smyth, Ian M

Volltext

IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction von Nold-Petry, Claudia A, Lo, Camden Y, Rudloff, Ina, Elgass, Kirstin D, Li, Suzhao, Gantier, Michael P, Lotz-Havla, Amelie S, Gersting, Søren W, Cho, Steven X, Lao, Jason C, Ellisdon, Andrew M, Rotter, Björn, Azam, Tania, Mangan, Niamh E, Rossello, Fernando J, Whisstock, James C, Bufler, Philip, Garlanda, Cecilia, Mantovani, Alberto, Dinarello, Charles A, Nold, Marcel F

Volltext

Structural basis of a unique interferon-β signaling axis mediated via the receptor IFNAR1 von de Weerd, Nicole A, Vivian, Julian P, Nguyen, Thao K, Mangan, Niamh E, Gould, Jodee A, Braniff, Susie-Jane, Zaker-Tabrizi, Leyla, Fung, Ka Yee, Forster, Samuel C, Beddoe, Travis, Reid, Hugh H, Rossjohn, Jamie, Hertzog, Paul J

Volltext

Interferon-ε Protects the Female Reproductive Tract from Viral and Bacterial Infection von Fung, Ka Yee, Mangan, Niamh E., Cumming, Helen, Horvat, Jay C., Mayall, Jemma R., Stifter, Sebastian A., De Weerd, Nicole, Roisman, Laila C., Rossjohn, Jamie, Robertson, Sarah A., Schjenken, John E., Parker, Belinda, Gargett, Caroline E., Nguyen, Hong P. T., Carr, Daniel J., Hansbro, Philip M., Hertzog, Paul J.

Volltext

Interferon-ε is a tumour suppressor and restricts ovarian cancer von Marks, Zoe R. C., Campbell, Nicole K., Mangan, Niamh E., Vandenberg, Cassandra J., Gearing, Linden J., Matthews, Antony Y., Gould, Jodee A., Tate, Michelle D., Wray-McCann, Georgie, Ying, Le, Rosli, Sarah, Brockwell, Natasha, Parker, Belinda S., Lim, San S., Bilandzic, Maree, Christie, Elizabeth L., Stephens, Andrew N., de Geus, Eveline, Wakefield, Matthew J., Ho, Gwo-Yaw, McNally, Orla, McNeish, Iain A., Bowtell, David D. L., de Weerd, Nicole A., Scott, Clare L., Bourke, Nollaig M., Hertzog, Paul J.

Volltext

The Use of CRISPR/Cas9 Gene Editing to Confirm Congenic Contaminations in Host-Pathogen Interaction Studies von Ferrand, Jonathan, Croft, Nathan P, Pépin, Geneviève, Diener, Kerrilyn R, Wu, Di, Mangan, Niamh E, Pedersen, John, Behlke, Mark A, Hayball, John D, Purcell, Anthony W, Ferrero, Richard L, Gantier, Michael P

Volltext

Identification of an interleukin (IL)-25-dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion von Fallon, Padraic G, Ballantyne, Sarah J, Mangan, Niamh E, Barlow, Jillian L, Dasvarma, Ayan, Hewett, Duncan R, McIlgorm, Ann, Jolin, Helen E, McKenzie, Andrew N J

Volltext