p27 controls Ragulator and mTOR activity in amino acid-deprived cells to regulate the autophagy–lysosomal pathway and coordinate cell cycle and cell growth von Nowosad, Ada, Jeannot, Pauline, Callot, Caroline, Creff, Justine, Perchey, Renaud Thierry, Joffre, Carine, Codogno, Patrice, Manenti, Stephane, Besson, Arnaud

Volltext

p27 controls autophagic vesicle trafficking in glucose-deprived cells via the regulation of ATAT1-mediated microtubule acetylation von Nowosad, Ada, Creff, Justine, Jeannot, Pauline, Culerrier, Raphael, Codogno, Patrice, Manenti, Stephane, Nguyen, Laurent, Besson, Arnaud

Volltext

Publisher Correction: p27 controls Ragulator and mTOR activity in amino acid-deprived cells to regulate the autophagy–lysosomal pathway and coordinate cell cycle and cell growth von Nowosad, Ada, Jeannot, Pauline, Callot, Caroline, Creff, Justine, Perchey, Renaud Thierry, Joffre, Carine, Codogno, Patrice, Manenti, Stephane, Besson, Arnaud

Volltext

The ROS/SUMO Axis Contributes to the Response of Acute Myeloid Leukemia Cells to Chemotherapeutic Drugs von Bossis, Guillaume, Sarry, Jean-Emmanuel, Kifagi, Chamseddine, Ristic, Marko, Saland, Estelle, Vergez, François, Salem, Tamara, Boutzen, Héléna, Baik, Hayeon, Brockly, Frédérique, Pelegrin, Mireia, Kaoma, Tony, Vallar, Laurent, Récher, Christian, Manenti, Stéphane, Piechaczyk, Marc

Volltext

Autophagy regulates fatty acid availability for oxidative phosphorylation through mitochondria-endoplasmic reticulum contact sites von Bosc, Claudie, Broin, Nicolas, Fanjul, Marjorie, Saland, Estelle, Farge, Thomas, Courdy, Charly, Batut, Aurélie, Masoud, Rawand, Larrue, Clément, Skuli, Sarah, Espagnolle, Nicolas, Pagès, Jean-Christophe, Carrier, Alice, Bost, Frédéric, Bertrand-Michel, Justine, Tamburini, Jérôme, Récher, Christian, Bertoli, Sarah, Mansat-De Mas, Véronique, Manenti, Stéphane, Sarry, Jean-Emmanuel, Joffre, Carine

Volltext

Targeting acute myeloid leukemia by dual inhibition of PI3K signaling and Cdk9-mediated Mcl-1 transcription von Thomas, Daniel, Powell, Jason A., Vergez, Francois, Segal, David H., Nguyen, Nhu-Y.N., Baker, Adele, Teh, Tse-Chieh, Barry, Emma F., Sarry, Jean-Emmanuel, Lee, Erwin M., Nero, Tracy L., Jabbour, Anissa M., Pomilio, Giovanna, Green, Benjamin D., Manenti, Stéphane, Glaser, Stefan P., Parker, Michael W., Lopez, Angel F., Ekert, Paul G., Lock, Richard B., Huang, David C.S., Nilsson, Susie K., Récher, Christian, Wei, Andrew H., Guthridge, Mark A.

Volltext

Inhibition of ubiquitin-specific protease 7 sensitizes acute myeloid leukemia to chemotherapy von Cartel, Maëlle, Mouchel, Pierre-Luc, Gotanègre, Mathilde, David, Laure, Bertoli, Sarah, Mansat-De Mas, Véronique, Besson, Arnaud, Sarry, Jean-Emmanuel, Manenti, Stéphane, Didier, Christine

Volltext

Proteasome inhibitors induce FLT3-ITD degradation through autophagy in AML cells von Larrue, Clément, Saland, Estelle, Boutzen, Héléna, Vergez, François, David, Marion, Joffre, Carine, Hospital, Marie-Anne, Tamburini, Jérôme, Delabesse, Eric, Manenti, Stéphane, Sarry, Jean Emmanuel, Récher, Christian

Volltext

Cytoplasmic p27Kip1 promotes tumorigenesis via suppression of RhoB activity von Calvayrac, Olivier, Nowosad, Ada, Cabantous, Stéphanie, Lin, Lin‐Po, Figarol, Sarah, Jeannot, Pauline, Serres, Murielle P, Callot, Caroline, Perchey, Renaud T, Creff, Justine, Taranchon‐Clermont, Estelle, Rouquette, Isabelle, Favre, Gilles, Pradines, Anne, Manenti, Stephane, Mazieres, Julien, Lee, Huei, Besson, Arnaud

Volltext

PIM2 kinase has a pivotal role in plasmablast generation and plasma cell survival, opening up novel treatment options in myeloma von Haas, Marion, Caron, Gersende, Chatonnet, Fabrice, Manenti, Stéphane, Alaterre, Elina, Devin, Julie, Delaloy, Céline, Bertolin, Giulia, Viel, Roselyne, Pignarre, Amandine, Llamas-Gutierrez, Francisco, Marchalot, Anne, Decaux, Olivier, Tarte, Karin, Delpy, Laurent, Moreaux, Jérôme, Fest, Thierry

Volltext

CHK1 as a therapeutic target to bypass chemoresistance in AML von David, Laure, Fernandez-Vidal, Anne, Bertoli, Sarah, Grgurevic, Srdana, Lepage, Benoît, Deshaies, Dominique, Prade, Naïs, Cartel, Maëlle, Larrue, Clément, Sarry, Jean-Emmanuel, Delabesse, Eric, Cazaux, Christophe, Didier, Christine, Récher, Christian, Manenti, Stéphane, Hoffmann, Jean-Sébastien

Volltext

STAT5-dependent regulation of CDC25A by miR-16 controls proliferation and differentiation in FLT3-ITD acute myeloid leukemia von Sueur, Gabrielle, Boutet, Alison, Gotanègre, Mathilde, Mansat-De Mas, Véronique, Besson, Arnaud, Manenti, Stéphane, Bertoli, Sarah

Volltext

Polo-like kinase 1 is overexpressed in acute myeloid leukemia and its inhibition preferentially targets the proliferation of leukemic cells von Renner, Annelies G., Dos Santos, Cédric, Recher, Christian, Bailly, Christian, Créancier, Laurent, Kruczynski, Anna, Payrastre, Bernard, Manenti, Stéphane

Volltext

A PIM-CHK1 signaling pathway regulates PLK1 phosphorylation and function during mitosis von Adam, Kévin, Cartel, Maëlle, Lambert, Mireille, David, Laure, Yuan, Lingli, Besson, Arnaud, Mayeux, Patrick, Manenti, Stéphane, Didier, Christine

Volltext

Targeting PP2A-dependent autophagy enhances sensitivity to ruxolitinib in JAK2V617F myeloproliferative neoplasms von Courdy, Charly, Platteeuw, Loïc, Ducau, Charlotte, De Araujo, Isabelle, Boet, Emeline, Sahal, Ambrine, Saland, Estelle, Edmond, Valérie, Tavitian, Suzanne, Bertoli, Sarah, Cougoul, Pierre, Granat, Fanny, Poillet, Laura, Marty, Caroline, Plo, Isabelle, Sarry, Jean-Emmanuel, Manenti, Stéphane, Mansat-De Mas, Véronique, Joffre, Carine

Volltext

Antileukemic Activity of 2-Deoxy-d-Glucose through Inhibition of N-Linked Glycosylation in Acute Myeloid Leukemia with FLT3-ITD or c-KIT Mutations von Larrue, Clément, Saland, Estelle, Vergez, François, Serhan, Nizar, Delabesse, Eric, Mansat-De Mas, Véronique, Hospital, Marie-Anne, Tamburini, Jérôme, Manenti, Stéphane, Sarry, Jean Emmanuel, Récher, Christian

Volltext

Translational Regulation by hnRNP H/F Is Essential for the Proliferation and Survival of Glioblastoma von Le Bras, Morgane, Gorelick, Noah, Pautet, Sylvain, Tyler, Betty, Manenti, Stéphane, Skuli, Nicolas, Millevoi, Stefania, Cammas, Anne

Volltext

Phosphorylation of CDC25A on SER283 in late S/G2 by CDK/cyclin complexes accelerates mitotic entry von Mazzolini, Laurent, Broban, Anaïs, Froment, Carine, Burlet-Schiltz, Odile, Besson, Arnaud, Manenti, Stéphane, Dozier, Christine

Volltext

High levels of CD34+CD38low/−CD123+ blasts are predictive of an adverse outcome in acute myeloid leukemia: a Groupe Ouest-Est des Leucémies Aiguës et Maladies du Sang (GOELAMS) stu... von VERGEZ, François, GREEN, Alexa S, DREYFUS, François, MANENTI, Stephane, DEMUR, Cecile, DELABESSE, Eric, LACOMBE, Catherine, MAYEUX, Patrick, BOUSCARY, Didier, RECHER, Christian, BARDET, Valerie, TAMBURINI, Jerome, SARRY, Jean-Emmanuel, GAILLARD, Baptiste, CORNILLET-LEFEBVRE, Pascale, PANNETIER, Melanie, NEYRET, Aymeric, CHAPUIS, Nicolas, IFRAH, Norbert

Volltext

High Levels of miR-7-5p Potentiate Crizotinib-Induced Cytokilling and Autophagic Flux by Targeting RAF1 in NPM-ALK Positive Lymphoma Cells von Sorrentino, Domenico, Frentzel, Julie, Mitou, Géraldine, Blasco, Rafael B, Torossian, Avédis, Hoareau-Aveilla, Coralie, Pighi, Chiara, Farcé, Manon, Meggetto, Fabienne, Manenti, Stéphane, Espinos, Estelle, Chiarle, Roberto, Giuriato, Sylvie

Volltext