Apoptosis related to telomere instability and cell cycle alterations in human glioma cells treated by new highly selective G-quadruplex ligands von Pennarun, Gaëlle, Granotier, Christine, Gauthier, Laurent R, Gomez, Dennis, Hoffschir, Françoise, Mandine, Eliane, Riou, Jean-François, Mergny, Jean-Louis, Mailliet, Patrick, Boussin, François D

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Stabilization of the c-myc gene promoter quadruplex by specific ligands’ inhibitors of telomerase von Lemarteleur, Thibault, Gomez, Dennis, Paterski, Rajaa, Mandine, Eliane, Mailliet, Patrick, Riou, Jean-François

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Preferential binding of a G-quadruplex ligand to human chromosome ends von Granotier, Christine, Pennarun, Gaëlle, Riou, Lydia, Hoffschir, Françoise, Gauthier, Laurent R., De Cian, Anne, Gomez, Dennis, Mandine, Eliane, Riou, Jean-François, Mergny, Jean-Louis, Mailliet, Patrick, Dutrillaux, Bernard, Boussin, François D.

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Bone-targeted Src SH2 inhibitors block Src cellular activity and osteoclast-mediated resorption von Violette, S.M, Guan, W, Bartlett, C, Smith, J.A, Bardelay, C, Antoine, E, Rickles, R.J, Mandine, E, van Schravendijk, M.R, Adams, S.E, Lynch, B.A, Shakespeare, W.C, Yang, M, Jacobsen, V.A, Takeuchi, C.S, Macek, K.J, Bohacek, R.S, Dalgarno, D.C, Weigele, M, Lesuisse, D, Sawyer, T.K, Baron, R

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SAR and X-ray. A New Approach Combining Fragment-Based Screening and Rational Drug Design:  Application to the Discovery of Nanomolar Inhibitors of Src SH2 von Lesuisse, Dominique, Lange, Gudrun, Deprez, Pierre, Bénard, Didier, Schoot, Bernard, Delettre, Georges, Marquette, Jean-Pierre, Broto, Pierre, Jean-Baptiste, Véronique, Bichet, Paulette, Sarubbi, Edoardo, Mandine, Eliane

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Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors von Lange, Gudrun, Lesuisse, Dominique, Deprez, Pierre, Schoot, Bernard, Loenze, Petra, Bénard, Didier, Marquette, Jean-Pierre, Broto, Pierre, Sarubbi, Edoardo, Mandine, Eliane

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Evidence that monoclonal antibody production kinetics is related to the integral of the viable cells curve in Batch systems von RENARD, J. M, SPAGNOLI, R, MAZIER, C, SALLES, M. F, MANDINE, E

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Imidazole-based ligands of the Src SH2 protein von DEPREZ, Pierre, MANDINE, Eliane, VERMOND, Annie, LESUISSE, Dominique

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Murine monoclonal antibodies to Klebsiella pneumoniae protect against lethal endotoxemia and experimental infection with capsulated K. pneumoniae von Mandine, E, Salles, M F, Zalisz, R, Guenounou, M, Smets, P

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Inhibition of Production of Tumor Necrosis Factor by Monoclonal Antibodies to Lipopolysaccharides von Vacheron, F., Mandine, E., Lenaour, R., Smets, P., Zalisz, R., Guenounou, M.

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Small ligands interacting with the phosphotyrosine binding pocket of the Src SH2 protein von DEPREZ, Pierre, MANDINE, Eliane, GOFFLO, Dominique, MEUNIER, Stéphane, LESUISSE, Dominique

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Protective Effects of Murine Monoclonal Antibodies in Experimental Septicemia: E. coli Antibodies Protect Against Different Serotypes of E. coli von Salles, Marie-France, Mandine, Eliane, Zalisz, René, Guenounou, Moncef, Smets, Pierre

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Targeting human telomerase for cancer therapeutics von Guittat, Lionel, Alberti, Patrizia, Gomez, Dennis, De Cian, Anne, Pennarun, Gaëlle, Lemarteleur, Thibault, Belmokhtar, Chafke, Paterski, Rajaa, Morjani, Hamid, Trentesaux, Chantal, Mandine, Eliane, Boussin, François, Mailliet, Patrick, Lacroix, Laurent, Riou, Jean-François, Mergny, Jean-Louis

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Principles Governing the Binding of a Class of Non-Peptidic Inhibitors to the SH2 Domain of src Studied by X-ray Analysis von Lange, Gudrun, Lesuisse, Dominique, Deprez, Pierre, Schoot, Bernard, Loenze, Petra, Bénard, Didier, Marquette, Jean-Pierre, Broto, Pierre, Sarubbi, Edoardo, Mandine, Eliane

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High-affinity Src-SH2 ligands which do not activate Tyr(527)-phosphorylated Src in an experimental in vivo system von Mandine, Eliane, Jean-Baptiste, Véronique, Vayssière, Béatrice, Gofflo, Dominique, Bénard, Didier, Sarubbi, Edoardo, Deprez, Pierre, Baron, Roland, Superti-Furga, Giulio, Lesuisse, Dominique

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Discovery of highly potent Src SH2 binders: Structure-activity studies and X-ray structures von DEPREZ, Pierre, BAHOLET, Isabelle, BURLET, Stéphane, LANGE, Gudrun, AMENGUAL, Remi, SCHOOT, Bernard, VERMOND, Annie, MANDINE, Eliane, LESUISSE, Dominique

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Discovery of Thioazepinone Ligands for Src SH2: From Non-specific to Specific Binding von Lesuisse, Dominique, Deprez, Pierre, Albert, Eva, Duc, Tran Thien, Sortais, Benoit, Gofflo, Dominique, Jean-Baptiste, Véronique, Marquette, Jean-Pierre, Schoot, Bernard, Sarubbi, Edoardo, Lange, Gudrun, Broto, Pierre, Mandine, Eliane

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Src homology-2 domain binding assays by scintillation proximity and surface plasmon resonance von Mandine, Eliane, Gofflo, Dominique, Jean-Baptiste, Véronique, Sarubbi, Edoardo, Touyer, Gaetan, Deprez, Pierre, Lesuisse, Dominique

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Protective effects of murine monoclonal antibodies in experimental septicemia: Escherichia coli antibodies protect against different serotypes of Escherichia coli von SALLES, M.-F, MANDINE, E, ZALISZ, R, GUENOUNOU, M, SMETS, P

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Toxicity and activity of purified trichosanthin von FERRARI, P, TRABAUD, M.-A, ROMMAIN, M, MANDINE, E, ZALISZ, R, DESGRANGES, C, SMETS, P

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