ATM and PRDM9 regulate SPO11-bound recombination intermediates during meiosis von Paiano, Jacob, Wu, Wei, Yamada, Shintaro, Sciascia, Nicholas, Callen, Elsa, Paola Cotrim, Ana, Deshpande, Rajashree A., Maman, Yaakov, Day, Amanda, Paull, Tanya T., Nussenzweig, André

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Topoisomerase II-Induced Chromosome Breakage and Translocation Is Determined by Chromosome Architecture and Transcriptional Activity von Canela, Andres, Maman, Yaakov, Huang, Shar-yin N., Wutz, Gordana, Tang, Wen, Zagnoli-Vieira, Guido, Callen, Elsa, Wong, Nancy, Day, Amanda, Peters, Jan-Michael, Caldecott, Keith W., Pommier, Yves, Nussenzweig, André

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Genome Organization Drives Chromosome Fragility von Canela, Andres, Maman, Yaakov, Jung, Seolkyoung, Wong, Nancy, Callen, Elsa, Day, Amanda, Kieffer-Kwon, Kyong-Rim, Pekowska, Aleksandra, Zhang, Hongliang, Rao, Suhas S.P., Huang, Su-Chen, Mckinnon, Peter J., Aplan, Peter D., Pommier, Yves, Aiden, Erez Lieberman, Casellas, Rafael, Nussenzweig, André

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The Energetics and Physiological Impact of Cohesin Extrusion von Vian, Laura, Pękowska, Aleksandra, Rao, Suhas S.P., Kieffer-Kwon, Kyong-Rim, Jung, Seolkyoung, Baranello, Laura, Huang, Su-Chen, El Khattabi, Laila, Dose, Marei, Pruett, Nathanael, Sanborn, Adrian L., Canela, Andres, Maman, Yaakov, Oksanen, Anna, Resch, Wolfgang, Li, Xingwang, Lee, Byoungkoo, Kovalchuk, Alexander L., Tang, Zhonghui, Nelson, Steevenson, Di Pierro, Michele, Cheng, Ryan R., Machol, Ido, St Hilaire, Brian Glenn, Durand, Neva C., Shamim, Muhammad S., Stamenova, Elena K., Onuchic, José N., Ruan, Yijun, Nussenzweig, Andre, Levens, David, Aiden, Erez Lieberman, Casellas, Rafael

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Dual Roles of Poly(dA:dT) Tracts in Replication Initiation and Fork Collapse von Tubbs, Anthony, Sridharan, Sriram, van Wietmarschen, Niek, Maman, Yaakov, Callen, Elsa, Stanlie, Andre, Wu, Wei, Wu, Xia, Day, Amanda, Wong, Nancy, Yin, Mianmian, Canela, Andres, Fu, Haiqing, Redon, Christophe, Pruitt, Steven C., Jaszczyszyn, Yan, Aladjem, Mirit I., Aplan, Peter D., Hyrien, Olivier, Nussenzweig, André

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53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination von Callen, Elsa, Zong, Dali, Wu, Wei, Wong, Nancy, Stanlie, Andre, Ishikawa, Momoko, Pavani, Raphael, Dumitrache, Lavinia C., Byrum, Andrea K., Mendez-Dorantes, Carlos, Martinez, Paula, Canela, Andres, Maman, Yaakov, Day, Amanda, Kruhlak, Michael J., Blasco, Maria A., Stark, Jeremy M., Mosammaparast, Nima, McKinnon, Peter J., Nussenzweig, André

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The Energetics and Physiological Impact of Cohesin Extrusion von Vian, Laura, Pękowska, Aleksandra, Rao, Suhas S.P., Kieffer-Kwon, Kyong-Rim, Jung, Seolkyoung, Baranello, Laura, Huang, Su-Chen, El Khattabi, Laila, Dose, Marei, Pruett, Nathanael, Sanborn, Adrian L., Canela, Andres, Maman, Yaakov, Oksanen, Anna, Resch, Wolfgang, Li, Xingwang, Lee, Byoungkoo, Kovalchuk, Alexander L., Tang, Zhonghui, Nelson, Steevenson, Di Pierro, Michele, Cheng, Ryan R., Machol, Ido, St Hilaire, Brian Glenn, Durand, Neva C., Shamim, Muhammad S., Stamenova, Elena K., Onuchic, José N., Ruan, Yijun, Nussenzweig, Andre, Levens, David, Aiden, Erez Lieberman, Casellas, Rafael

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Ig Enhancers Increase RNA Polymerase II Stalling at Somatic Hypermutation Target Sequences von Tarsalainen, Alina, Maman, Yaakov, Meng, Fei-Long, Kyläniemi, Minna K, Soikkeli, Anni, Budzyńska, Paulina, McDonald, Jessica J, Šenigl, Filip, Alt, Frederic W, Schatz, David G, Alinikula, Jukka

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Intra-Vκ Cluster Recombination Shapes the Ig Kappa Locus Repertoire von Shinoda, Kenta, Maman, Yaakov, Canela, Andres, Schatz, David G., Livak, Ferenc, Nussenzweig, André

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Topologically Associated Domains Delineate Susceptibility to Somatic Hypermutation von Senigl, Filip, Maman, Yaakov, Dinesh, Ravi K., Alinikula, Jukka, Seth, Rashu B., Pecnova, Lubomira, Omer, Arina D., Rao, Suhas S.P., Weisz, David, Buerstedde, Jean-Marie, Aiden, Erez Lieberman, Casellas, Rafael, Hejnar, Jiri, Schatz, David G.

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HCV Infection Increases the Expression of ACE2 Receptor, Leading to Enhanced Entry of Both HCV and SARS-CoV-2 into Hepatocytes and a Coinfection State von Domovitz, Tom, Ayoub, Samer, Werbner, Michal, Alter, Joel, Izhaki Tavor, Lee, Yahalom-Ronen, Yfat, Tikhonov, Evgeny, Meirson, Tomer, Maman, Yaakov, Paran, Nir, Israely, Tomer, Dessau, Moshe, Gal-Tanamy, Meital

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Bcl6 Is Required for Somatic Hypermutation and Gene Conversion in Chicken DT40 Cells von Williams, Alan M, Maman, Yaakov, Alinikula, Jukka, Schatz, David G

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Immune-Induced Evolutionary Selection Focused on a Single Reading Frame in Overlapping Hepatitis B Virus Proteins von MAMAN, Yaakov, BLANCHER, Antoine, BENICHOU, Jennifer, YABLONKA, Adi, EFRONI, Sol, LOUZOUN, Yoram

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Bacteria modulate the CD8+ T cell epitope repertoire of host cytosol-exposed proteins to manipulate the host immune response von Maman, Yaakov, Nir-Paz, Ran, Louzoun, Yoram

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Image-based pooled whole-genome CRISPRi screening for subcellular phenotypes von Kanfer, Gil, Sarraf, Shireen A, Maman, Yaakov, Baldwin, Heather, Dominguez-Martin, Eunice, Johnson, Kory R, Ward, Michael E, Kampmann, Martin, Lippincott-Schwartz, Jennifer, Youle, Richard J

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Genomic landscape of cutaneous T cell lymphoma von Choi, Jaehyuk, Goh, Gerald, Walradt, Trent, Hong, Bok S, Bunick, Christopher G, Chen, Kan, Bjornson, Robert D, Maman, Yaakov, Wang, Tiffany, Tordoff, Jesse, Carlson, Kacie, Overton, John D, Liu, Kristina J, Lewis, Julia M, Devine, Lesley, Barbarotta, Lisa, Foss, Francine M, Subtil, Antonio, Vonderheid, Eric C, Edelson, Richard L, Schatz, David G, Boggon, Titus J, Girardi, Michael, Lifton, Richard P

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Immunoglobulin enhancers increase RNA polymerase 2 stalling at somatic hypermutation target sequences von Tarsalainen, Alina, Maman, Yaakov, Meng, Fei-Long, Kyläniemi, Minna K., Soikkeli, Anni, Budzynska, Paulina, McDonald, Jessica J., Šenigl, Filip, Alt, Frederic W., Schatz, David G., Alinikula, Jukka

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RAG Represents a Widespread Threat to the Lymphocyte Genome von Teng, Grace, Maman, Yaakov, Resch, Wolfgang, Kim, Min, Yamane, Arito, Qian, Jason, Kieffer-Kwon, Kyong-Rim, Mandal, Malay, Ji, Yanhong, Meffre, Eric, Clark, Marcus R., Cowell, Lindsay G., Casellas, Rafael, Schatz, David G.

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RAG1 targeting in the genome is dominated by chromatin interactions mediated by the non-core regions of RAG1 and RAG2 von Maman, Yaakov, Teng, Grace, Seth, Rashu, Kleinstein, Steven H, Schatz, David G

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Viral CD8 T cell epitope nucleotide composition shows evidence of short- and long-term evolutionary strategies von Maman, Yaakov, Hershberg, Uri, Louzoun, Yoram

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