Virus-Tumor Interactome Screen Reveals ER Stress Response Can Reprogram Resistant Cancers for Oncolytic Virus-Triggered Caspase-2 Cell Death von Mahoney, Douglas J., Lefebvre, Charles, Allan, Kristina, Brun, Jan, Sanaei, Cina A., Baird, Stephen, Pearce, Nelson, Grönberg, Susanna, Wilson, Brian, Prakesh, Mikael, Aman, Ahmed, Isaac, Methvin, Mamai, Ahmed, Uehling, David, Al-Awar, Rima, Falls, Theresa, Alain, Tommy, Stojdl, David F.

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Discovery of Nanomolar DCAF1 Small Molecule Ligands von Li, Alice Shi Ming, Kimani, Serah, Wilson, Brian, Noureldin, Mahmoud, González-Álvarez, Héctor, Mamai, Ahmed, Hoffer, Laurent, Guilinger, John P., Zhang, Ying, von Rechenberg, Moritz, Disch, Jeremy S., Mulhern, Christopher J., Slakman, Belinda L., Cuozzo, John W., Dong, Aiping, Poda, Gennady, Mohammed, Mohammed, Saraon, Punit, Mittal, Manish, Modh, Pratik, Rathod, Vaibhavi, Patel, Bhashant, Ackloo, Suzanne, Santhakumar, Vijayaratnam, Szewczyk, Magdalena M, Barsyte-Lovejoy, Dalia, Arrowsmith, Cheryl H., Marcellus, Richard, Guié, Marie-Aude, Keefe, Anthony D., Brown, Peter J., Halabelian, Levon, Al-awar, Rima, Vedadi, Masoud

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Crystal structures of DCAF1-PROTAC-WDR5 ternary complexes provide insight into DCAF1 substrate specificity von Mabanglo, Mark F., Wilson, Brian, Noureldin, Mahmoud, Kimani, Serah W., Mamai, Ahmed, Krausser, Chiara, González-Álvarez, Héctor, Srivastava, Smriti, Mohammed, Mohammed, Hoffer, Laurent, Chan, Manuel, Avrumutsoae, Jamie, Li, Alice Shi Ming, Hajian, Taraneh, Tucker, Sarah, Green, Stuart, Szewczyk, Magdalena, Barsyte-Lovejoy, Dalia, Santhakumar, Vijayaratnam, Ackloo, Suzanne, Loppnau, Peter, Li, Yanjun, Seitova, Almagul, Kiyota, Taira, Wang, Jue George, Privé, Gilbert G., Kuntz, Douglas A., Patel, Bhashant, Rathod, Vaibhavi, Vala, Anand, Rout, Bhimsen, Aman, Ahmed, Poda, Gennady, Uehling, David, Ramnauth, Jailall, Halabelian, Levon, Marcellus, Richard, Al-awar, Rima, Vedadi, Masoud

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Ibrexafungerp: An orally active β-1,3-glucan synthesis inhibitor von Apgar, James M., Wilkening, Robert R., Parker, Dann L., Meng, Dongfang, Wildonger, Kenneth J., Sperbeck, Donald, Greenlee, Mark L., Balkovec, James M., Flattery, Amy M., Abruzzo, George K., Galgoci, Andrew M., Giacobbe, Robert A., Gill, Charles J., Hsu, Ming-Jo, Liberator, Paul, Misura, Andrew S., Motyl, Mary, Nielsen Kahn, Jennifer, Powles, Maryann, Racine, Fred, Dragovic, Jasminka, Fan, Weiming, Kirwan, Robin, Lee, Shu, Liu, Hao, Mamai, Ahmed, Nelson, Kingsley, Peel, Michael

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Leveraging an Open Science Drug Discovery Model to Develop CNS-Penetrant ALK2 Inhibitors for the Treatment of Diffuse Intrinsic Pontine Glioma von Smil, David, Wong, Jong Fu, Williams, Eleanor P, Adamson, Roslin J, Howarth, Alison, McLeod, David A, Mamai, Ahmed, Kim, Soyoung, Wilson, Brian J, Kiyota, Taira, Aman, Ahmed, Owen, Julie, Poda, Gennady, Horiuchi, Kurumi Y, Kuznetsova, Ekaterina, Ma, Haiching, Hamblin, J. Nicole, Cramp, Sue, Roberts, Owen G, Edwards, Aled M, Uehling, David, Al-awar, Rima, Bullock, Alex N, O’Meara, Jeff A, Isaac, Methvin B

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Solid-Phase Guanidinylation as a Diversification Strategy of Poly-l-proline Type II Peptide Mimic Scaffolds von Mamai, Ahmed, Madalengoitia, Jose S

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Chemical Genetics Screen Identifies COPB2 Tool Compounds That Alters ER Stress Response and Induces RTK Dysregulation in Lung Cancer Cells von Saraon, Punit, Snider, Jamie, Schormann, Wiebke, Rai, Ankit, Radulovich, Nikolina, Sánchez-Osuna, Maria, Coulombe-Huntington, Jasmin, Huard, Caroline, Mohammed, Mohammed, Lima-Fernandes, Evelyne, Thériault, Brigitte, Halabelian, Levon, Chan, Manuel, Joshi, Dhananjay, Drecun, Luka, Yao, Zhong, Pathmanathan, Shivanthy, Wong, Victoria, Lyakisheva, Anna, Aboualizadeh, Farzaneh, Niu, Li, Li, Fengling, Kiyota, Taira, Subramanian, Ratheesh, Joseph, Babu, Aman, Ahmed, Prakesch, Michael, Isaac, Methvin, Mamai, Ahmed, Poda, Gennady, Vedadi, Masoud, Marcellus, Richard, Uehling, David, Leighl, Natasha, Sacher, Adrian, Samaržija, Miroslav, Jakopović, Marko, Arrowsmith, Cheryl, Tyers, Mike, Tsao, Ming-Sound, Andrews, David, Al-awar, Rima, Stagljar, Igor

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Abstract 7: Discovery of OICR-10268: A potent and selective BCL6 inhibitor von Watson, Iain D., Isaac, Methvin, Wilson, Brian, Chau, Anh, Morin, Justin, Subramanian, Pandiaraju, Mamai, Ahmed, Joseph, Babu, Prakesch, Michael, Uehling, David, Abibi, Ayome, Marcellus, Richard, Strathdee, Craig, Subramaniam, Ratheesh, Theriault, Brigitte, Winston, Jeffrey, Chan, Manuel, Griffin, Carly, Cheung, Herman, Kiyota, Taira, Undzys, Elijus, Aman, Ahmed, Poda, Gennady, Kuntz, Doug, Pomroy, Neil C., Privé, Gil G., Al-awar, Rima

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MK-5204: An orally active β-1,3-glucan synthesis inhibitor von Apgar, James M., Wilkening, Robert R., Parker, Dann L., Meng, Dongfang, Wildonger, Kenneth J., Sperbeck, Donald, Greenlee, Mark L., Balkovec, James M., Flattery, Amy M., Abruzzo, George K., Galgoci, Andrew M., Giacobbe, Robert A., Gill, Charles J., Hsu, Ming-Jo, Liberator, Paul, Misura, Andrew S., Motyl, Mary, Kahn, Jennifer Nielsen, Powles, Maryann, Racine, Fred, Dragovic, Jasminka, Fan, Weiming, Kirwan, Robin, Lee, Shu, Liu, Hao, Mamai, Ahmed, Nelson, Kingsley, Peel, Michael

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Discovery of OICR12694: A Novel, Potent, Selective, and Orally Bioavailable BCL6 BTB Inhibitor von Mamai, Ahmed, Chau, Anh M., Wilson, Brian J., Watson, Iain D., Joseph, Babu B., Subramanian, Pandiaraju R., Morshed, Monzur M., Morin, Justin A., Prakesch, Michael A., Lu, Tianbao, Connolly, Pete, Kuntz, Douglas A., Pomroy, Neil C., Poda, Gennady, Nguyen, Kong, Marcellus, Richard, Strathdee, Graig, Theriault, Brigitte, Subramaniam, Ratheesh, Mohammed, Mohammed, Abibi, Ayome, Chan, Manuel, Winston, Jeffrey, Kiyota, Taira, Undzys, Elijus, Aman, Ahmed, Austin, Nigel, Du Jardin, Marc, Packman, Kathryn, Phillippar, Ulrike, Attar, Riccardo, Edwards, James, O’Meara, Jeff, Uehling, David E., Al-awar, Rima, Privé, Gilbert G., Isaac, Methvin B.

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NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) INHIBITOR-CONJUGATES AND USES THEREOF von Mamai, Ahmed

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NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) INHIBITOR-CONJUGATES AND USES THEREOF von MAMAI, Ahmed

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Novel orally active inhibitors of β-1,3-glucan synthesis derived from enfumafungin von Apgar, James M., Wilkening, Robert R., Greenlee, Mark L., Balkovec, James M., Flattery, Amy M., Abruzzo, George K., Galgoci, Andrew M., Giacobbe, Robert A., Gill, Charles J., Hsu, Ming Jo, Liberator, Paul, Misura, Andrew S., Motyl, Mary, Nielsen Kahn, Jennifer, Powles, Maryann, Racine, Fred, Dragovic, Jasminka, Habulihaz, Bahanu, Fan, Weiming, Kirwan, Robin, Lee, Shu, Liu, Hao, Mamai, Ahmed, Nelson, Kingsley, Peel, Michael

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NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) INHIBITOR-CONJUGATES AND USES THEREOF von MAMAI, Ahmed

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NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) INHIBITOR-CONJUGATES AND USES THEREOF von MAMAI, Ahmed

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NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) INHIBITOR-CONJUGATES AND USES THEREOF von MAMAI, AHMED

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NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) INHIBITOR-CONJUGATES AND USES THEREOF von MAMAI, Ahmed

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Synthesis and biological evaluation of antifungal derivatives of enfumafungin as orally bioavailable inhibitors of β-1,3-glucan synthase von Heasley, Brian H., Pacofsky, Gregory J., Mamai, Ahmed, Liu, Hao, Nelson, Kingsley, Coti, Ghjuvanni, Peel, Michael R., Balkovec, James M., Greenlee, Mark L., Liberator, Paul, Meng, Dongfang, Parker, Dann L., Wilkening, Robert R., Apgar, James M., Racine, F., Hsu, Ming Jo, Giacobbe, Robert A., Kahn, Jennifer Nielsen

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Strategies for the Solid-Phase Diversification of Poly-l-proline-Type II Peptide Mimic Scaffolds and Peptide Scaffolds Through Guanidinylation von Flemer, Stevenson, Wurthmann, Alexander, Mamai, Ahmed, Madalengoitia, José S

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NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) INHIBITOR-CONJUGATES AND USES THEREOF von MAMAI, Ahmed

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