Antitumor activity of SCH 66336, an orally bioavailable tricyclic inhibitor of farnesyl protein transferase, in human tumor xenograft models and Wap-ras transgenic mice von MING LIU, BRYANT, M. S, DELL, J, SINHA, D, SYED, J, KORFMACHER, W. A, NOMEIR, A. A, LIN, C.-C, WANG, L, TAVERAS, A. G, DOLL, R. J, NJOROGE, F. G, JIANPING CHEN, MALLAMS, A. K, REMISZEWSKI, S, CATINO, J. J, GIRIJAVALLABHAN, V. M, KIRSCHMEIER, P, BISHOP, W. R, SUINING LEE, YAREMKO, B, LIPARI, P, MALKOWSKI, M, FERRARI, E, NIELSEN, L, PRIOLI, N

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Tricyclic Farnesyl Protein Transferase Inhibitors:  Crystallographic and Calorimetric Studies of Structure−Activity Relationships von Strickland, Corey L, Weber, Patricia C, Windsor, William T, Wu, Zhen, Le, Hung V, Albanese, Margaret M, Alvarez, Carmen S, Cesarz, David, del Rosario, Joycelyn, Deskus, Jeffrey, Mallams, Alan K, Njoroge, F. George, Piwinski, John J, Remiszewski, Stacy, Rossman, Randall R, Taveras, Arthur G, Vibulbhan, Bancha, Doll, Ronald J, Girijavallabhan, Viyyoor M, Ganguly, Ashit K

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(+)-4-[2-[4-(8-Chloro-3,10-dibromo-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]- pyridin-11(R)-yl)-1-piperidinyl]-2-oxo-ethyl]-1-piperidinecarboxamide (SCH-66336):  A Very Potent Fa... von Njoroge, F. George, Taveras, Arthur G, Kelly, Joseph, Remiszewski, Stacy, Mallams, Alan K, Wolin, Ronald, Afonso, Adriano, Cooper, Alan B, Rane, Dinananth F, Liu, Yi-Tsung, Wong, Jesse, Vibulbhan, Bancha, Pinto, Patrick, Deskus, Jeffrey, Alvarez, Carmen S, del Rosario, Joycelyn, Connolly, Michael, Wang, James, Desai, Jagdish, Rossman, Randall R, Bishop, W. Robert, Patton, Robert, Wang, Lynn, Kirschmeier, Paul, Bryant, Mathew S, Nomeir, Amin A, Lin, C.-C, Liu, Ming, McPhail, Andrew T, Doll, Ronald J, Girijavallabhan, Viyyoor M, Ganguly, Ashit K

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Identification of Pharmacokinetically Stable 3,10-Dibromo-8-chlorobenzocycloheptapyridine Farnesyl Protein Transferase Inhibitors with Potent Enzyme and Cellular Activities von Taveras, Arthur G, Deskus, Jeff, Chao, Jianping, Vaccaro, Cynthia J, Njoroge, F. George, Vibulbhan, Bancha, Pinto, Pat, Remiszewski, Stacy, del Rosario, Jocelyn, Doll, Ronald J, Alvarez, Carmen, Lalwani, Tarik, Mallams, Alan K, Rossman, Randall R, Afonso, Adriano, Girijavallabhan, Viyyoor M, Ganguly, Ashit K, Pramanik, Birendra, Heimark, Larry, Bishop, W. Robert, Wang, Lynn, Kirschmeier, Paul, James, Linda, Carr, Donna, Patton, Robert, Bryant, Mathew S, Nomeir, Amin A, Liu, Ming

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Inhibitors of Farnesyl Protein Transferase. 4-Amido, 4-Carbamoyl, and 4-Carboxamido Derivatives of 1-(8-Chloro-6,11-dihydro-5H-benzo[5,6]- cyclohepta[1,2-b]pyridin-11-yl)piperazine... von Mallams, Alan K, Rossman, Randall R, Doll, Ronald J, Girijavallabhan, Viyyoor M, Ganguly, Ashit K, Petrin, Joanne, Wang, Lynn, Patton, Robert, Bishop, W. Robert, Carr, Donna M, Kirschmeier, Paul, Catino, Joseph J, Bryant, Matthew S, Chen, Kwang-Jong, Korfmacher, Walter A, Nardo, Cymbelene, Wang, Shiyong, Nomeir, Amin A, Lin, Chin-Chung, Li, Zujun, Chen, Jianping, Lee, Suining, Dell, Janet, Lipari, Philip, Malkowski, Michael, Yaremko, Bodan, King, Ivan, Liu, Ming

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Kijanimicin. 1. Structures of the individual sugar components von Mallams, Alan K, Puar, Mohindar S, Rossman, Randall R

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Kijanimicin. 2. Structure and absolute stereochemistry of kijanimicin von Mallams, Alan K, Puar, Mohindar S, Rossman, Randall R, McPhail, Andrew T, Macfarlane, Ronald D

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Semisynthetic aminoglycoside antibacterials. 6. Synthesis of sisomicin, antibiotic G-52, and novel 6'-substituted analogs of sisomicin from aminoglycoside 66-40C von Davies, D. Huw, Mallams, Alan K, Counelis, Mae, Loebenberg, David, Moss, Eugene L, Waitz, J. Allan

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Carotenoids and related compounds. Part 38. Synthesis of (3RS,3′RS)-alloxanthin and other acetylenes von Davies, Anthony J., Khare, Anakshi, Mallams, Alan K., Massy-Westropp, Ralph A., Moss, Gerard P., Weedon, Basil C. L.

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Megalomicins. 6. Tertiary glycosidic macrolide antibiotics. A structural revision by carbon-13 nuclear magnetic resonance and x-ray crystallography von Ton That Thang, Lukacs, Gabor, Omura, Satoshi, Bartner, Peter, Boxler, Dena L, Brambilla, Raymond, Mallams, Alan K, Morton, James B, Reichert, Paul

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The megalomicins. Part 7. A structural revision by carbon-13 nuclear magnetic resonance and X-ray crystallography. Synthesis and conformational analysis of 3-dimethylamino- and 3-a... von Bartner, Peter, Boxler, Dena L., Brambilla, Raymond, Mallams, Alan K., Morton, James B., Reichert, Paul, Sancilio, Frederick D., Surprenant, Henry, Tomalesky, Gregory, Lukacs, Gabor, Olesker, Alain, Thang, Ton That, Valente, Lydia, Omura, Satoshi

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Structures of the aminoglycoside antibiotics 66-40B and 66-40D produced by Micromonospora inyoensis von Davies, D H, Greeves, D, Mallams, A K, Morton, J B, Tkach, R W

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Novel 3-O-α- L -cladinosyl sixteen-membered macrolide antibacterials von Mallams, Alan K., Rossman, Randall R.

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Semisynthetic macrolide antibacterials derived from tylosin. Synthesis of 23-O-demycinosyltylosin and related compounds von Mallams, Alan K., Rossman, Randall R.

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The megalomicins. Part III. D-Rhodosamine, a new dimethylamino-sugar von Mallams, Alan K.

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Kijanimicin. Part 3. Structure and absolute stereochemistry of kijanimicin von Mallams, Alan K., Puar, Mohindar S., Rossman, Randall R., McPhail, Andrew T., Macfarlane, Ronald D., Stephens, Richard L.

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Effects of SCH 59228, an orally bioavailable farnesyl protein transferase inhibitor, on the growth of oncogene-transformed fibroblasts and a human colon carcinoma xenograft in nude... von MING LIU, BRYANT, M. S, ROSSMAN, R. R, KORFMACHER, W. A, NOMEIR, A. A, LIN, C.-C, MALLAMS, A. K, DOLL, R. J, CATINO, J. J, GIRIJAVALLABHAN, V. M, KIRSCHMEIER, P, BISHOP, W. R, JIANPING CHEN, SUININHG LEE, YAREMKO, B, ZUJUN LI, DELL, J, LIPARI, P, MALKOWSKI, M, PRIOLI, N

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Megalomicins. I. d-Rhodosamine, a new dimethylamino sugar von Mallams, Alan K

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Semisynthetic macrolide antibacterials derived from tylosin. Synthesis of 3-O-acetyl-23-O-demycinosyl-4″-O-isovaleryltylosin and related compounds, as well as the 12,13-epoxy deriv... von Fishman, Andrew G., Mallams, Alan K., Rossman, Randall R.

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Semisynthetic aminoglycoside antibacterials. Part 10. Synthesis of novel 1-N-aminoalkoxycarbonyl and 1-N-aminoalkylcarboxamido derivatives of sisomicin, gentamicin B, gentamicin C1... von Mallams, Alan K., Morton, James B., Reichert, Paul

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