Knowledge Based Prediction of Ligand Binding Modes and Rational Inhibitor Design for Kinase Drug Discovery von Ghose, Arup K, Herbertz, Torsten, Pippin, Douglas A, Salvino, Joseph M, Mallamo, John P

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Discovery of a Potent, Selective, and Orally Active Proteasome Inhibitor for the Treatment of Cancer von Dorsey, Bruce D, Iqbal, Mohamed, Chatterjee, Sankar, Menta, Ernesto, Bernardini, Raffaella, Bernareggi, Alberto, Cassarà, Paolo G, D’Arasmo, Germano, Ferretti, Edmondo, De Munari, Sergio, Oliva, Ambrogio, Pezzoni, Gabriella, Allievi, Cecilia, Strepponi, Ivan, Ruggeri, Bruce, Ator, Mark A, Williams, Michael, Mallamo, John P

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Discovery and Characterization of 6-{4-[3-(R)-2-Methylpyrrolidin-1-yl)propoxy]phenyl}-2H-pyridazin-3-one (CEP-26401, Irdabisant): A Potent, Selective Histamine H3 Receptor Inverse... von Hudkins, Robert L, Raddatz, Rita, Tao, Ming, Mathiasen, Joanne R, Aimone, Lisa D, Becknell, Nadine C, Prouty, Catherine P, Knutsen, Lars J. S, Yazdanian, Mehran, Moachon, Gilbert, Ator, Mark A, Mallamo, John P, Marino, Michael J, Bacon, Edward R, Williams, Michael

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Knowledge-based chemoinformatic approaches to drug discovery von Ghose, Arup K., Herbertz, Torsten, Salvino, Joseph M., Mallamo, John P.

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Structure-guided identification of novel VEGFR-2 kinase inhibitors via solution phase parallel synthesis von Tripathy, Rabindranath, Reiboldt, Alyssa, Messina, Patricia A., Iqbal, Mohamed, Singh, Jasbir, Bacon, Edward R., Angeles, Thelma S., Yang, Shi X., Albom, Mark S., Robinson, Candy, Chang, Hong, Ruggeri, Bruce A., Mallamo, John P.

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Knowledge-Based, Central Nervous System (CNS) Lead Selection and Lead Optimization for CNS Drug Discovery von Ghose, Arup K, Herbertz, Torsten, Hudkins, Robert L, Dorsey, Bruce D, Mallamo, John P

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Synthesis and Mixed Lineage Kinase Activity of Pyrrolocarbazole and Isoindolone Analogs of (+)K-252a von Hudkins, Robert L, Johnson, Neil W, Angeles, Thelma S, Gessner, George W, Mallamo, John P

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1,2-Benzothiazine 1,1-dioxide α-ketoamide analogues as potent calpain I inhibitors von BIHOVSKY, Ron, MING TAO, MALLAMO, John P, WELLS, Gregory J

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Neurotrophic 3,9-Bis[(alkylthio)methyl]- and -Bis(alkoxymethyl)-K-252a Derivatives von Kaneko, Masami, Saito, Yutaka, Saito, Hiromitsu, Matsumoto, Tadashi, Matsuda, Yuzuru, Vaught, Jeffry L, Dionne, Craig A, Angeles, Thelma S, Glicksman, Marcie A, Neff, Nicola T, Rotella, David P, Kauer, James C, Mallamo, John P, Hudkins, Robert L, Murakata, Chikara

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A New Class of Potent Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitors:  Structure−Activity Relationships for a Series of 9-Alkoxymethyl-12-(3-hydroxypropyl)i... von Gingrich, Diane E, Reddy, Dandu R, Iqbal, Mohamed A, Singh, Jasbir, Aimone, Lisa D, Angeles, Thelma S, Albom, Mark, Yang, Shi, Ator, Mark A, Meyer, Sheryl L, Robinson, Candy, Ruggeri, Bruce A, Dionne, Craig A, Vaught, Jeffry L, Mallamo, John P, Hudkins, Robert L

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Synthesis and Biological Profile of the pan-Vascular Endothelial Growth Factor Receptor/Tyrosine Kinase with Immunoglobulin and Epidermal Growth Factor-Like Homology Domains 2 (VEG... von Hudkins, Robert L, Becknell, Nadine C, Zulli, Allison L, Underiner, Ted L, Angeles, Thelma S, Aimone, Lisa D, Albom, Mark S, Chang, Hong, Miknyoczki, Sheila J, Hunter, Kathryn, Jones-Bolin, Susan, Zhao, Hugh, Bacon, Edward R, Mallamo, John P, Ator, Mark A, Ruggeri, Bruce A

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Salt Lake City Cemetery, Jewish Section von Mallamo, P. D.

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Novel Peptidyl Phosphorus Derivatives as Inhibitors of Human Calpain I von Tao, Ming, Bihovsky, Ron, Wells, Gregory J, Mallamo, John P

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1,2,3-Thiadiazole substituted pyrazolones as potent KDR/VEGFR-2 kinase inhibitors von Tripathy, Rabindranath, Ghose, Arup, Singh, Jasbir, Bacon, Edward R., Angeles, Thelma S., Yang, Shi X., Albom, Mark S., Aimone, Lisa D., Herman, Joseph L., Mallamo, John P.

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TrkA kinase inhibitors from a library of modified and isosteric Staurosporine aglycone von Tripathy, Rabindranath, Angeles, Thelma S., Yang, Shi X., Mallamo, John P.

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Antipicornavirus activity of tetrazole analogs related to disoxaril von Diana, Guy D, Cutcliffe, David, Volkots, Deborah L, Mallamo, John P, Bailey, Thomas R, Vescio, Niranjan, Oglesby, Richard C, Nitz, Theodore J, Wetzel, Joseph

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d-Amino Acid Containing, High-Affinity Inhibitors of Recombinant Human Calpain I von Chatterjee, Sankar, Gu, Zi-Qiang, Dunn, Derek, Tao, Ming, Josef, Kurt, Tripathy, Rabindranath, Bihovsky, Ron, Senadhi, Shobha E, O'Kane, Teresa M, McKenna, Beth Ann, Mallya, Satish, Ator, Mark A, Bozyczko-Coyne, Donna, Siman, Robert, Mallamo, John P

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Synthesis and Biological Activity of a Series of Potent Fluoromethyl Ketone Inhibitors of Recombinant Human Calpain I von Chatterjee, Sankar, Ator, Mark A, Bozyczko-Coyne, Donna, Josef, Kurt, Wells, Gregory, Tripathy, Rabindranath, Iqbal, Mohamed, Bihovsky, Ron, Senadhi, Shobha E, Mallya, Satish, O'Kane, Teresa M, McKenna, Beth Ann, Siman, Robert, Mallamo, John P

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Daily Engine Performance Trending Using Common Flight Regime Identification von Mallamo, Declan P., Azarian, Michael H., Pecht, Michael G.

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Mixed-Lineage Kinase 1 and Mixed-Lineage Kinase 3 Subtype-Selective Dihydronaphthyl[3,4-a]pyrrolo[3,4-c]carbazole-5-ones: Optimization, Mixed-Lineage Kinase 1 Crystallography, and... von Hudkins, Robert L, Diebold, James L, Tao, Ming, Josef, Kurt A, Park, Chung Ho, Angeles, Thelma S, Aimone, Lisa D, Husten, Jean, Ator, Mark A, Meyer, Sheryl L, Holskin, Beverly P, Durkin, John T, Fedorov, Alexander A, Fedorov, Elena V, Almo, Steven C, Mathiasen, Joanne R, Bozyczko-Coyne, Donna, Saporito, Michael S, Scott, Richard W, Mallamo, John P

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