Supraspinal cholecystokinin may drive tonic descending facilitation mechanisms to maintain neuropathic pain in the rat von Kovelowski, C.J., Ossipov, M.H., Sun, H., Lai, J., Malan, T.P., Porreca, F.

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Tonic Descending Facilitation from the Rostral Ventromedial Medulla Mediates Opioid-Induced Abnormal Pain and Antinociceptive Tolerance von Vanderah, Todd W, Suenaga, Nova M. H, Ossipov, Michael H, Malan, T. Philip, Jr, Lai, Josephine, Porreca, Frank

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Dynorphin Promotes Abnormal Pain and Spinal Opioid Antinociceptive Tolerance von Vanderah, Todd W, Gardell, Luis R, Burgess, Shannon E, Ibrahim, Mohab, Dogrul, Ahmet, Zhong, Cheng-Min, Zhang, En-Tan, Malan, T. Philip, Jr, Ossipov, Michael H, Lai, Josephine, Porreca, Frank

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Pronociceptive Actions of Dynorphin Maintain Chronic Neuropathic Pain von Wang, Zaijie, Gardell, Luis R, Ossipov, Michael H, Vanderah, Todd W, Brennan, Miles B, Hochgeschwender, Ute, Hruby, Victor J, Malan, T. Phil, Jr, Lai, Josephine, Porreca, Frank

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Spinal NK-1 receptor-expressing neurons and descending pathways support fentanyl-induced pain hypersensitivity in a rat model of postoperative pain von Rivat, Cyril, Vera-Portocarrero, Louis P., Ibrahim, Mohab M., Mata, Heriberto P., Stagg, Nicola J., De Felice, Milena, Porreca, Frank, Malan, T. P.

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Lack of involvement of capsaicin-sensitive primary afferents in nerve-ligation injury induced tactile allodynia in rats von Ossipov, Michael H., Bian, Di, Malan, T.Philip, Lai, Josephine, Porreca, Frank

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Nerve injury-induced tactile allodynia is mediated via ascending spinal dorsal column projections von Sun, H, Ren, K, Zhong, C.M, Ossipov, M.H, Malan, T.P, Lai, J, Porreca, F

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Mouse strains that lack spinal dynorphin upregulation after peripheral nerve injury do not develop neuropathic pain von Gardell, L.R, Ibrahim, M, Wang, R, Wang, Z, Ossipov, M.H, Malan, T.P, Porreca, F, Lai, J

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Mechanisms of opioid-induced pain and antinociceptive tolerance: descending facilitation and spinal dynorphin von Vanderah, Todd W., Ossipov, Michael H., Lai, Josephine, Malan, T.Philip, Porreca, Frank

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Peripheral and spinal antihyperalgesic activity of SIB-1757, a metabotropic glutamate receptor (mGLUR 5) antagonist, in experimental neuropathic pain in rats von Dogrul, Ahmet, Ossipov, Michael H, Lai, Josephine, Malan, T.Philip, Porreca, Frank

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Extraterritorial neuropathic pain correlates with multisegmental elevation of spinal dynorphin in nerve-injured rats von Malan, T.Philip, Ossipov, Michael H, Gardell, Luis R, Ibrahim, Mohab, Bian, Di, Lai, Josephine, Porreca, Frank

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Spinal and Supraspinal Mechanisms of Neuropathic Pain von OSSIPOV, MICHAEL H., LAI, JOSEPHINE, MALAN JR, T. PHILIP, PORRECA, FRANK

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Single intrathecal injections of dynorphin A or des-Tyr-dynorphins produce long-lasting allodynia in rats: blockade by MK-801 but not naloxone von Vandera, Todd W, Laughlin, Tinna, Lashbrook, Jason M., Nichols, Michael L., Wilcox, George L., Ossipov, Michael H., Malan, T.Philip, Porreca, Frank

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Inhibition of neuropathic pain by selective ablation of brainstem medullary cells expressing the mu-opioid receptor von Porreca, F, Burgess, S E, Gardell, L R, Vanderah, T W, Malan, Jr, T P, Ossipov, M H, Lappi, D A, Lai, J

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Tactile allodynia, but not thermal hyperalgesia, of the hindlimbs is blocked by spinal transection in rats with nerve injury von Bian, Di, Ossipov, Michael H, Zhong, Chengmin, Malan, T.Philip, Porreca, Frank

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Loss of antiallodynic and antinociceptive spinal/supraspinal morphine synergy in nerve-injured rats: restoration by MK-801 or dynorphin antiserum von Bian, Di, Ossipov, Michael H., Ibrahim, Mohab, Raffa, Robert B., Tallarida, Ronald J., Malan, T.Philip, Lai, Josephine, Porreca, Frank

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Differential activities of intrathecal MK-801 or morphine to alter responses to thermal and mechanical stimuli in normal or nerve-injured rats von Wegert, Sandra, Ossipov, Michael H, Nichols, Michael L, Bian, Di, Vanderah, Todd W, Malan Jr, T.Philip, Porreca, Frank

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Cardiovascular effects of sevoflurane compared with those of isoflurane in volunteers von MALAN, T. P, DINARDO, J. A, ISNER, R. J, FRINK, E. J, GOLDERG, M, FENSTER, P. E, BROWN, E. A, DEPA, R, HAMMOND, L. C, MATA, H

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Pronociceptive effects of spinal dynorphin promote cannabinoid-induced pain and antinociceptive tolerance von Gardell, L.R, Burgess, S.E, Dogrul, A, Ossipov, M.H, Malan, T.P, Lai, J, Porreca, F

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Renal toxicity with sevoflurane: A storm in a teacup? von GENTZ, Brenda A, MALAN, T. Philip

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