Epigenetic polypharmacology: A new frontier for epi‐drug discovery von Tomaselli, Daniela, Lucidi, Alessia, Rotili, Dante, Mai, Antonello

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Polycomb Repressive Complex 2 Modulation through the Development of EZH2–EED Interaction Inhibitors and EED Binders von Tomassi, Stefano, Romanelli, Annalisa, Zwergel, Clemens, Valente, Sergio, Mai, Antonello

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Epi-drugs to fight cancer: From chemistry to cancer treatment, the road ahead von Mai, Antonello, Altucci, Lucia

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LSD1 inhibitors for cancer treatment: Focus on multi-target agents and compounds in clinical trials von Noce, Beatrice, Di Bello, Elisabetta, Fioravanti, Rossella, Mai, Antonello

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Sirt4: A Multifaceted Enzyme at the Crossroads of Mitochondrial Metabolism and Cancer von Tomaselli, Daniela, Steegborn, Clemens, Mai, Antonello, Rotili, Dante

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Six Years (2012–2018) of Researches on Catalytic EZH2 Inhibitors: The Boom of the 2‐Pyridone Compounds von Fioravanti, Rossella, Stazi, Giulia, Zwergel, Clemens, Valente, Sergio, Mai, Antonello

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Epi-drugs in combination with immunotherapy: a new avenue to improve anticancer efficacy von Mazzone, Roberta, Zwergel, Clemens, Mai, Antonello, Valente, Sergio

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Intergenerational inheritance of high fat diet-induced cardiac lipotoxicity in Drosophila von Guida, Maria Clara, Birse, Ryan Tyge, Dall’Agnese, Alessandra, Toto, Paula Coutinho, Diop, Soda Balla, Mai, Antonello, Adams, Peter D., Puri, Pier Lorenzo, Bodmer, Rolf

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The Innovative Potential of Statins in Cancer: New Targets for New Therapies von Di Bello, Elisabetta, Zwergel, Clemens, Mai, Antonello, Valente, Sergio

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Crystal structures of the mitochondrial deacylase Sirtuin 4 reveal isoform-specific acyl recognition and regulation features von Pannek, Martin, Simic, Zeljko, Fuszard, Matthew, Meleshin, Marat, Rotili, Dante, Mai, Antonello, Schutkowski, Mike, Steegborn, Clemens

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Lysine Acetyltransferase Inhibitors From Natural Sources von Fiorentino, Francesco, Mai, Antonello, Rotili, Dante

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Sirtuin functions and modulation: from chemistry to the clinic von Carafa, Vincenzo, Rotili, Dante, Forgione, Mariantonietta, Cuomo, Francesca, Serretiello, Enrica, Hailu, Gebremedhin Solomon, Jarho, Elina, Lahtela-Kakkonen, Maija, Mai, Antonello, Altucci, Lucia

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SIRT5 regulation of ammonia-induced autophagy and mitophagy von Polletta, Lucia, Vernucci, Enza, Carnevale, Ilaria, Arcangeli, Tania, Rotili, Dante, Palmerio, Silvia, Steegborn, Clemens, Nowak, Theresa, Schutkowski, Mike, Pellegrini, Laura, Sansone, Luigi, Villanova, Lidia, Runci, Alessandra, Pucci, Bruna, Morgante, Emanuela, Fini, Massimo, Mai, Antonello, Russo, Matteo A, Tafani, Marco

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Oxidative stress and epigenetic regulation in ageing and age-related diseases von Cencioni, Chiara, Spallotta, Francesco, Martelli, Fabio, Valente, Sergio, Mai, Antonello, Zeiher, Andreas M, Gaetano, Carlo

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Sex-dependent Effects of the Drugs of Abuse Amphetamine and the Smart Drug 3,4-Methylenedioxypyrovalerone on Fear Memory Generalization in Rats von Riccardi, Eleonora, Blasi, Eleonora, Zwergel, Clemens, Mai, Antonello, Morena, Maria, Campolongo, Patrizia

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Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors von Kalin, Jay H., Wu, Muzhou, Gomez, Andrea V., Song, Yun, Das, Jayanta, Hayward, Dawn, Adejola, Nkosi, Wu, Mingxuan, Panova, Izabela, Chung, Hye Jin, Kim, Edward, Roberts, Holly J., Roberts, Justin M., Prusevich, Polina, Jeliazkov, Jeliazko R., Roy Burman, Shourya S., Fairall, Louise, Milano, Charles, Eroglu, Abdulkerim, Proby, Charlotte M., Dinkova-Kostova, Albena T., Hancock, Wayne W., Gray, Jeffrey J., Bradner, James E., Valente, Sergio, Mai, Antonello, Anders, Nicole M., Rudek, Michelle A., Hu, Yong, Ryu, Byungwoo, Schwabe, John W. R., Mattevi, Andrea, Alani, Rhoda M., Cole, Philip A.

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Current HDAC Inhibitors in Clinical Trials von Di Bello, Elisabetta, Noce, Beatrice, Fioravanti, Rossella, Mai, Antonello

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Simultaneous administration of EZH2 and BET inhibitors inhibits proliferation and clonogenic ability of metastatic prostate cancer cells von Negri, Aide, Marozzi, Marina, Trisciuoglio, Daniela, Rotili, Dante, Mai, Antonello, Rizzi, Federica

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RIP1-HAT1-SIRT Complex Identification and Targeting in Treatment and Prevention of Cancer von Carafa, Vincenzo, Nebbioso, Angela, Cuomo, Francesca, Rotili, Dante, Cobellis, Gilda, Bontempo, Paola, Baldi, Alfonso, Spugnini, Enrico P, Citro, Gennaro, Chambery, Angela, Russo, Rosita, Ruvo, Menotti, Ciana, Paolo, Maravigna, Luca, Shaik, Jani, Radaelli, Enrico, De Antonellis, Pasquale, Tarantino, Domenico, Pirolli, Adele, Ragno, Rino, Zollo, Massimo, Stunnenberg, Hendrik G, Mai, Antonello, Altucci, Lucia

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Metabolic Rewiring by Loss of Sirt5 Promotes Kras-Induced Pancreatic Cancer Progression von Hu, Tuo, Shukla, Surendra K., Vernucci, Enza, He, Chunbo, Wang, Dezhen, King, Ryan J., Jha, Kanupriya, Siddhanta, Kasturi, Mullen, Nicholas J., Attri, Kuldeep S., Murthy, Divya, Chaika, Nina V., Thakur, Ravi, Mulder, Scott E., Pacheco, Camila G., Fu, Xiao, High, Robin R., Yu, Fang, Lazenby, Audrey, Steegborn, Clemens, Lan, Ping, Mehla, Kamiya, Rotili, Dante, Chaudhary, Sarika, Valente, Sergio, Tafani, Marco, Mai, Antonello, Auwerx, Johan, Verdin, Eric, Tuveson, David, Singh, Pankaj K.

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