Apolipoprotein E4: A Causative Factor and Therapeutic Target in Neuropathology, including Alzheimer's Disease von Mahley, Robert W., Weisgraber, Karl H., Huang, Yadong

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Putting cholesterol in its place: apoE and reverse cholesterol transport von Mahley, Robert W, Huang, Yadong, Weisgraber, Karl H

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APOLIPOPROTEIN E: Far More Than a Lipid Transport Protein von Mahley, Robert W, Rall, Stanley C

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Lipid- and Receptor-Binding Regions of Apolipoprotein E4 Fragments Act in Concert to Cause Mitochondrial Dysfunction and Neurotoxicity von Shengjun Chang, Tian ran Ma, R. Dennis Miranda, Balestra, Maureen E., Mahley, Robert W., Huang, Yadong

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Apolipoprotein (Apo) E4 Enhances Amyloid β Peptide Production in Cultured Neuronal Cells: Apoe Structure as a Potential Therapeutic Target von Shiming Ye, Huang, Yadong, Karin Müllendorff, Liming Dong, Gretchen Giedt, Meng, Elaine C., Cohen, Fred E., Kuntz, Irwin D., Weisgraber, Karl H., Mahley, Robert W.

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Neuron-Specific Apolipoprotein E4 Proteolysis Is Associated with Increased Tau Phosphorylation in Brains of Transgenic Mice von Brecht, Walter J, Harris, Faith M, Chang, Shengjun, Tesseur, Ina, Yu, Gui-Qiu, Xu, Qin, Dee Fish, Jo, Wyss-Coray, Tony, Buttini, Manuel, Mucke, Lennart, Mahley, Robert W, Huang, Yadong

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Remnant lipoprotein metabolism: key pathways involving cell-surface heparan sulfate proteoglycans and apolipoprotein E von Mahley, R W, Ji, Z S

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Carboxyl-Terminal-Truncated Apolipoprotein E4 Causes Alzheimer's Disease-like Neurodegeneration and Behavioral Deficits in Transgenic Mice von Harris, Faith M., Brecht, Walter J., Xu, Qin, Tesseur, Ina, Kekonius, Lisa, Wyss-Coray, Tony, Fish, Jo Dee, Masliah, Eliezer, Hopkins, Paul C., Scearce-Levie, Kimberly, Weisgraber, Karl H., Mucke, Lennart, Mahley, Robert W., Huang, Yadong

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A role for apolipoprotein E, apolipoprotein A-I, and low density lipoprotein receptors in cholesterol transport during regeneration and remyelination of the rat sciatic nerve von BOYLES, J. K, ZOELLNER, C. D, SHOOTER, E. M, ANDERSON, L. J, KOSIK, L. M, PITAS, R. E, WEISGRABER, K. H, HUI, D. Y, MAHLEY, R. W, GEBICKE-HAERTER, P. J, IGNATIUS, M. J

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Increased tau phosphorylation in apolipoprotein E4 transgenic mice is associated with activation of extracellular signal-regulated kinase: modulation by zinc von Harris, Faith M, Brecht, Walter J, Xu, Qin, Mahley, Robert W, Huang, Yadong

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Apolipoprotein E Fragments Present in Alzheimer's Disease Brains Induce Neurofibrillary Tangle-like Intracellular Inclusions in Neurons von Huang, Y, Liu, X Q, Wyss-Coray, T, Brecht, W J, Sanan, D A, Mahley, R W

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Apolipoprotein E: from atherosclerosis to Alzheimer's disease and beyond von Mahley, R W, Huang, Y

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Pathogenesis of type III hyperlipoproteinemia (dysbetalipoproteinemia). Questions, quandaries, and paradoxes von Mahley, R W, Huang, Y, Rall, Jr, S C

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Reactivity of apolipoprotein E4 and amyloid beta peptide: lysosomal stability and neurodegeneration von Ji, Zhong-Sheng, Müllendorff, Karin, Cheng, Irene H, Miranda, R Dennis, Huang, Yadong, Mahley, Robert W

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Expression of Human Apolipoprotein E3 or E4 in the Brains of Apoe-/- Mice: Isoform-Specific Effects on Neurodegeneration von Buttini, Manuel, Orth, Matthias, Bellosta, Stefano, Akeefe, Hassibullah, Pitas, Robert E, Wyss-Coray, Tony, Mucke, Lennart, Mahley, Robert W

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Isoform-Specific Effects of Human Apolipoprotein E on Brain Function Revealed in ApoE Knockout Mice: Increased Susceptibility of Females von Raber, Jacob, Wong, Derek, Buttini, Manuel, Orth, Matthias, Bellosta, Stefano, Pitas, Robert E., Mahley, Robert W., Mucke, Lennart

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Apolipoprotein E4 potentiates amyloid beta peptide-induced lysosomal leakage and apoptosis in neuronal cells von Ji, Zhong-Sheng, Miranda, R Dennis, Newhouse, Yvonne M, Weisgraber, Karl H, Huang, Yadong, Mahley, Robert W

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Astroglial regulation of apolipoprotein E expression in neuronal cells. Implications for Alzheimer's disease von Harris, Faith M, Tesseur, Ina, Brecht, Walter J, Xu, Qin, Mullendorff, Karin, Chang, Shengjun, Wyss-Coray, Tony, Mahley, Robert W, Huang, Yadong

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Apolipoprotein E: Cholesterol Transport Protein with Expanding Role in Cell Biology von Mahley, Robert W.

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Apolipoprotein E4 Domain Interaction Occurs in Living Neuronal Cells as Determined by Fluorescence Resonance Energy Transfer von Xu, Qin, Brecht, Walter J., Weisgraber, Karl H., Mahley, Robert W., Huang, Yadong

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