Conformational Plasticity of the Immunoglobulin Fc Domain in Solution von Remesh, Soumya G., Armstrong, Anthony A., Mahan, Andrew D., Luo, Jinquan, Hammel, Michal

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Functional Relevance of Interleukin-1 Receptor Inter-domain Flexibility for Cytokine Binding and Signaling von Ge, Jiwan, Remesh, Soumya G., Hammel, Michal, Pan, Si, Mahan, Andrew D., Wang, Shuying, Wang, Xinquan

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"Stapling" scFv for multispecific biotherapeutics of superior properties von Boucher, Lauren E, Prinslow, Elisabeth Geyer, Feldkamp, Michael, Yi, Fang, Nanjunda, Rupesh, Wu, Sheng-Jiun, Liu, Tun, Lacy, Eilyn R, Jacobs, Steven, Kozlyuk, Natalia, Del Rosario, Brian, Wu, Bingyuan, Aquino, Patricia, Davidson, Robert C, Heyne, Samantha, Mazzanti, Nicholas, Testa, James, Diem, Michael D, Gorre, Elsa, Mahan, Andrew, Nanda, Hirsh, Gunawardena, Harsha P, Gervais, Alexis, Armstrong, Anthony A, Teplyakov, Alexey, Huang, Chichi, Zwolak, Adam, Chowdhury, Partha, Cheung, Wan Cheung, Luo, Jinquan

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Thrombogenic Collagen-Mimetic Peptides: Self-Assembly of Triple Helix-Based Fibrils Driven by Hydrophobic Interactions von Cejas, Mabel A., Kinney, William A., Chen, Cailin, Vinter, Jeremy G., Almond, Harold R., Balss, Karin M., Maryanoff, Cynthia A., Schmidt, Ute, Breslav, Michael, Mahan, Andrew, Lacy, Eilyn, Maryanoff, Bruce E.

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Structural Basis for Elastolytic Substrate Specificity in Rodent α-Chymases von Kervinen, Jukka, Abad, Marta, Crysler, Carl, Kolpak, Michael, Mahan, Andrew D., Masucci, John A., Bayoumy, Shariff, Cummings, Maxwell D., Yao, Xiang, Olson, Matthew, de Garavilla, Lawrence, Kuo, Lawrence, Deckman, Ingrid, Spurlino, John

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Functional Relevance of IL-1 Receptor Inter-domain Flexibility for Cytokine Binding and Signaling von Ge, Jiwan, Remesh, Soumya G., Hammel, Michal, Pan, Si, Mahan, Andrew D., Wang, Shuying, Wang, Xinquan

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Residue-Specific Impact of EDTA and Methionine on Protein Oxidation in Biotherapeutics Formulations Using an Integrated Biotherapeutics Drug Product Development Workflow von Thakkar, Santosh V., Rodrigues, Danika, Zhai, Bo, Banton, Dwaine, Somani, Sandeep, Javidi, Alex, Mahan, Andrew, Ember, Stuart, DeGrazio, Dominick, Ganguly, Subinay, Amin, Ketan, Nanda, Hirsh

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Conformational Plasticity of the Immunoglobulin Fc Domain in Solution von Remesh, Soumya G., Armstrong, Anthony A., Mahan, Andrew D., Luo, Jinquan, Hammel, Michal

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Fc plasticity studies by small-angle X-ray scattering (SAXS) von Remesh, Soumya Govinda, Armstrong, Anthony, Luo, Jinquan, Mahan, Andrew, Hammel, Michal

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Cleaved SLPI, a novel biomarker of chymase activity von Belkowski, Stanley M., Masucci, John, Mahan, Andrew, Kervinen, Jukka, Olson, Matthew, de Garavilla, Lawrence, D'Andrea, Michael R.

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Suzuki−Miyaura Approach to JNJ-26076713, an Orally Active Tetrahydroquinoline-Containing αVβ3/αVβ5 Integrin Antagonist. Enantioselective Synthesis and Stereochemical Studies von Kinney, William A, Teleha, Christopher A, Thompson, Andrew S, Newport, Maria, Hansen, Ryan, Ballentine, Scott, Ghosh, Shyamali, Mahan, Andrew, Grasa, Gabriela, Zanotti-Gerosa, Antonio, Dingenen, Jules, Schubert, Carsten, Zhou, Yong, Leo, Gregory C, McComsey, David F, Santulli, Rosemary J, Maryanoff, Bruce E

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Suzuki-Miyaura approach to JNJ-26076713, an orally active tetrahydroquinoline-containing alphaVbeta3/alphaVbeta5 integrin antagonist. enantioselective synthesis and stereochemical... von Kinney, William A, Teleha, Christopher A, Thompson, Andrew S, Newport, Maria, Hansen, Ryan, Ballentine, Scott, Ghosh, Shyamali, Mahan, Andrew, Grasa, Gabriela, Zanotti-Gerosa, Antonio, Dingenen, Jules, Schubert, Carsten, Zhou, Yong, Leo, Gregory C, McComsey, David F, Santulli, Rosemary J, Maryanoff, Bruce E

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Suzuki−Miyaura Approach to JNJ-26076713, an Orally Active Tetrahydroquinoline-Containing α V β 3 /α V β 5 Integrin Antagonist. Enantioselective Synthesis and Stereochemical Studies... von Kinney, William A., Teleha, Christopher A., Thompson, Andrew S., Newport, Maria, Hansen, Ryan, Ballentine, Scott, Ghosh, Shyamali, Mahan, Andrew, Grasa, Gabriela, Zanotti-Gerosa, Antonio, Dingenen, Jules, Schubert, Carsten, Zhou, Yong, Leo, Gregory C., McComsey, David F., Santulli, Rosemary J., Maryanoff, Bruce E.

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Suzuki-Miyaura Approach to JNJ-26076713, an Orally Active Tetrahydroquinoline-Containing αVβ3αVβ5 Integrin Antagonist. Enantioselective Synthesis and Stereochemical Studies von KINNEY, William A, TELEHA, Christopher A, DINGENEN, Jules, SCHUBERT, Carsten, YONG ZHOU, LEO, Gregory C, MCCOMSEY, David F, SANTULLI, Rosemary J, MARYANOFF, Bruce E, THOMPSON, Andrew S, NEWPORT, Maria, HANSEN, Ryan, BALLENTINE, Scott, GHOSH, Shyamali, MAHAN, Andrew, GRASA, Gabriela, ZANOTTI-GEROSA, Antonio

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COMPOSITIONS COMPRISING ENHANCED MULTISPECIFIC BINDING AGENTS FOR AN IMMUNE RESPONSE von HUANG, Chichi, ARMSTRONG, Anthony, LUO, Jinquan, FELDKAMP, Michael, NANDA, Hirsh, POLTASH, Michael Lawrence, BOUCHER, Lauren, GUNAWARDENA, Harsha Prithviraj, CHOWDHURY, Partha, PRINSLOW, Elisabeth Geyer, TEPLYAKOV, Alexey, DIEM, Michael, MAHAN, Andrew David

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COMPOSITIONS COMPRISING ENHANCED MULTISPECIFIC BINDING AGENTS FOR AN IMMUNE RESPONSE von HUANG, Chichi, ARMSTRONG, Anthony, LUO, Jinquan, FELDKAMP, Michael, NANDA, Hirsh, POLTASH, Michael Lawrence, BOUCHER, Lauren, GUNAWARDENA, Harsha Prithviraj, CHOWDHURY, Partha, PRINSLOW, Elisabeth Geyer, TEPLYAKOV, Alexey, DIEM, Michael, MAHAN, Andrew David

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COMPOSITIONS COMPRISING ENHANCED MULTISPECIFIC BINDING AGENTS FOR AN IMMUNE RESPONSE von GUNAWARDENA, HARSHA PRITHVIRAJ, DIEM, MICHAEL, MAHAN, ANDREW DAVID, PRINSLOW, ELISABETH GEYER, BOUCHER, LAUREN, HUANG, CHICHI, ARMSTRONG, ANTHONY, NANDA, HIRSH, LUO, JINQUAN, FELDKAMP, MICHAEL, TEPLYAKOV, ALEXEY, POLTASH, MICHAEL LAWRENCE, CHOWDHURY, PARTHA

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Structural Basis for Elastolytic Substrate Specificity in Rodent α-Chymases von Jukka Kervinen, Marta Abad, Carl Crysler, Michael Kolpak, Andrew D. Mahan, John A. Masucci, Shariff Bayoumy, Maxwell D. Cummings, Xiang Yao, Matthew Olson, Lawrence de Garavilla, Lawrence Kuo, Ingrid Deckman, John Spurlino

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"Stapling" scFv for multispecific biotherapeutics of superior properties von Boucher, Lauren E., Prinslow, Elisabeth Geyer, Feldkamp, Michael, Yi, Fang, Nanjunda, Rupesh, Wu, Sheng-Jiun, Liu, Tun, Lacy, Eilyn R., Jacobs, Steven, Kozlyuk, Natalia, Del Rosario, Brian, Wu, Bingyuan, Aquino, Patricia, Davidson, Robert C., Heyne, Samantha, Mazzanti, Nicholas, Testa, James, Diem, Michael D., Gorre, Elsa, Mahan, Andrew, Nanda, Hirsh, Gunawardena, Harsha P., Gervais, Alexis, Armstrong, Anthony A., Teplyakov, Alexey, Huang, Chichi, Zwolak, Adam, Chowdhury, Partha, Cheung, Wan Cheung, Luo, Jinquan

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Compositions comprising enhanced multispecific binding agents for immune responses von FELDKAMP MARC, CHOWDHURY PARTHA, LUO JINQUAN, ARMSTRONG ALAN, GUNAWARDENA, HIMANSHU, P, DEEM MARK, MAHAN ANDREW DAVID, TEPLYAKOV ALEXEY, NANDA HARISH, HUANG, CHENG, BUCHER LAURENT, POTASH, MICHAEL, L, PRINSLOW EDWARD G

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