The Identification and Pharmacological Characterization of 6‑(tert-Butylsulfonyl)‑N‑(5-fluoro‑1H‑indazol-3-yl)quinolin-4-amine (GSK583), a Highly Potent and Selective Inhibitor of... von Haile, Pamela A, Votta, Bartholomew J, Marquis, Robert W, Bury, Michael J, Mehlmann, John F, Singhaus, Robert, Charnley, Adam K, Lakdawala, Ami S, Convery, Máire A, Lipshutz, David B, Desai, Biva M, Swift, Barbara, Capriotti, Carol A, Berger, Scott B, Mahajan, Mukesh K, Reilly, Michael A, Rivera, Elizabeth J, Sun, Helen H, Nagilla, Rakesh, Beal, Allison M, Finger, Joshua N, Cook, Michael N, King, Bryan W, Ouellette, Michael T, Totoritis, Rachel D, Pierdomenico, Maria, Negroni, Anna, Stronati, Laura, Cucchiara, Salvatore, Ziółkowski, Bartłomiej, Vossenkämper, Anna, MacDonald, Thomas T, Gough, Peter J, Bertin, John, Casillas, Linda N

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Dual negative precursor ion scan approach for rapid detection of glutathione conjugates using liquid chromatography/tandem mass spectrometry von Mahajan, Mukesh K., Evans, Christopher A.

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RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer von Wang, Wei, Marinis, Jill M., Beal, Allison M., Savadkar, Shivraj, Wu, Yue, Khan, Mohammed, Taunk, Pardeep S., Wu, Nan, Su, Wenyu, Wu, Jingjing, Ahsan, Aarif, Kurz, Emma, Chen, Ting, Yaboh, Inedouye, Li, Fei, Gutierrez, Johana, Diskin, Brian, Hundeyin, Mautin, Reilly, Michael, Lich, John D., Harris, Philip A., Mahajan, Mukesh K., Thorpe, James H., Nassau, Pamela, Mosley, Julie E., Leinwand, Joshua, Kochen Rossi, Juan A., Mishra, Ankita, Aykut, Berk, Glacken, Michael, Ochi, Atsuo, Verma, Narendra, Kim, Jacqueline I., Vasudevaraja, Varshini, Adeegbe, Dennis, Almonte, Christina, Bagdatlioglu, Ece, Cohen, Deirdre J., Wong, Kwok-Kin, Bertin, John, Miller, George

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RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer von Wang, Wei, Marinis, Jill M., Beal, Allison M., Savadkar, Shivraj, Wu, Yue, Khan, Mohammed, Taunk, Pardeep S., Wu, Nan, Su, Wenyu, Wu, Jingjing, Ahsan, Aarif, Kurz, Emma, Chen, Ting, Yaboh, Inedouye, Li, Fei, Gutierrez, Johana, Diskin, Brian, Hundeyin, Mautin, Reilly, Michael, Lich, John D., Harris, Philip A., Mahajan, Mukesh K., Thorpe, James H., Nassau, Pamela, Mosley, Julie E., Leinwand, Joshua, Kochen Rossi, Juan A., Mishra, Ankita, Aykut, Berk, Glacken, Michael, Ochi, Atsuo, Verma, Narendra, Kim, Jacqueline I., Vasudevaraja, Varshini, Adeegbe, Dennis, Almonte, Christina, Bagdatlioglu, Ece, Cohen, Deirdre J., Wong, Kwok-Kin, Bertin, John, Miller, George

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Identification of a RIP1 Kinase Inhibitor Clinical Candidate (GSK3145095) for the Treatment of Pancreatic Cancer von Harris, Philip A, Marinis, Jill M, Lich, John D, Berger, Scott B, Chirala, Anirudh, Cox, Julie A, Eidam, Patrick M, Finger, Joshua N, Gough, Peter J, Jeong, Jae U, Kang, James, Kasparcova, Viera, Leister, Lara K, Mahajan, Mukesh K, Miller, George, Nagilla, Rakesh, Ouellette, Michael T, Reilly, Michael A, Rendina, Alan R, Rivera, Elizabeth J, Sun, Helen H, Thorpe, James H, Totoritis, Rachel D, Wang, Wei, Wu, Dongling, Zhang, Daohua, Bertin, John, Marquis, Robert W

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Understanding Pharmacokinetic Disconnect in Preclinical Species for 4-Aminoquinolines: Consequences of Low Permeability and High P-glycoprotein Efflux Ratio on Rat and Dog Oral Pha... von Mahajan, Mukesh K., Rivera, Elizabeth J., Sun, Helen H., Nagilla, Rakesh, DeMartino, Michael P., Haile, Pamela A., Casillas, Linda N., Marquis, Robert W., Votta, Bartholomew J., Bertin, John, Reilly, Michael A.

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Identification and Characterization of Oxymetazoline Glucuronidation in Human Liver Microsomes: Evidence for the Involvement of UGT1A9 von Mahajan, Mukesh K., Uttamsingh, Vinita, Gan, Liang-Shang, Leduc, Barbara, Williams, David A.

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In Vitro Metabolism of Oxymetazoline: Evidence for Bioactivation to a Reactive Metabolite von MAHAJAN, Mukesh K, UTTAMSINGH, Vinita, DANIELS, J. Scott, GAN, Liang-Shang, LEDUC, Barbara W, WILLIAMS, David A

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Biological control of hairy root (Rhizobium rhizogenes) in apple nurseries through Rhizobium radiobacter antagonists (strain K-84 and native strain UHFBA-218) von Kumar Junta, Mukesh, Gupta, A.K., Mahajan, Rishi

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Identification of Quinoline-Based RIP2 Kinase Inhibitors with an Improved Therapeutic Index to the hERG Ion Channel von Haile, Pamela A, Casillas, Linda N, Bury, Michael J, Mehlmann, John F, Singhaus, Robert, Charnley, Adam K, Hughes, Terry V, DeMartino, Michael P, Wang, Gren Z, Romano, Joseph J, Dong, Xiaoyang, Plotnikov, Nikolay V, Lakdawala, Ami S, Convery, Maire A, Votta, Bartholomew J, Lipshutz, David B, Desai, Biva M, Swift, Barbara, Capriotti, Carol A, Berger, Scott B, Mahajan, Mukesh K, Reilly, Michael A, Rivera, Elizabeth J, Sun, Helen H, Nagilla, Rakesh, LePage, Carol, Ouellette, Michael T, Totoritis, Rachel D, Donovan, Brian T, Brown, Barry S, Chaudhary, Khuram W, Gough, Peter J, Bertin, John, Marquis, Robert W

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Correction to Identification of Quinoline-Based RIP2 Kinase Inhibitors with an Improved Therapeutic Index to the hERG Ion Channel von Haile, Pamela A., Casillas, Linda N., Bury, Michael J., Mehlmann, John F., Singhaus, Robert, Charnley, Adam K., Hughes, Terry V., DeMartino, Michael P., Wang, Gren Z., Romano, Joseph J., Dong, Xiaoyang, Plotnikov, Nikolay V., Lakdawala, Ami S., Duraiswami, Chaya, Convery, Maire A., Votta, Bartholomew J., Lipshutz, David B., Desai, Biva M., Swift, Barbara, Capriotti, Carol A., Berger, Scott B., Mahajan, Mukesh K., Reilly, Michael A., Rivera, Elizabeth J., Sun, Helen H., Nagilla, Rakesh, LePage, Carol, Ouellette, Michael T., Totoritis, Rachel D., Donovan, Brian T., Brown, Barry S., Chaudhary, Khuram W., Gough, Peter J., Bertin, John, Marquis, Robert W.

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Discovery and Lead-Optimization of 4,5-Dihydropyrazoles as Mono-Kinase Selective, Orally Bioavailable and Efficacious Inhibitors of Receptor Interacting Protein 1 (RIP1) Kinase von Harris, Philip A, Faucher, Nicolas, George, Nicolas, Eidam, Patrick M, King, Bryan W, White, Gemma V, Anderson, Niall A, Bandyopadhyay, Deepak, Beal, Allison M, Beneton, Veronique, Berger, Scott B, Campobasso, Nino, Campos, Sebastien, Capriotti, Carol A, Cox, Julie A, Daugan, Alain, Donche, Frederic, Fouchet, Marie-Hélène, Finger, Joshua N, Geddes, Brad, Gough, Peter J, Grondin, Pascal, Hoffman, Bonnie L, Hoffman, Sandra J, Hutchinson, Susan E, Jeong, Jae U, Jigorel, Emilie, Lamoureux, Pauline, Leister, Lara K, Lich, John D, Mahajan, Mukesh K, Meslamani, Jamel, Mosley, Julie E, Nagilla, Rakesh, Nassau, Pamela M, Ng, Sze-Ling, Ouellette, Michael T, Pasikanti, Kishore K, Potvain, Florent, Reilly, Michael A, Rivera, Elizabeth J, Sautet, Stéphane, Schaeffer, Michelle C, Sehon, Clark A, Sun, Helen, Thorpe, James H, Totoritis, Rachel D, Ward, Paris, Wellaway, Natalie, Wisnoski, David D, Woolven, James M, Bertin, John, Marquis, Robert W

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Discovery of a First-in-Class Receptor Interacting Protein 2 (RIP2) Kinase Specific Clinical Candidate, 2‑((4-(Benzo[d]­thiazol-5-ylamino)-6‑(tert-butylsulfonyl)­quinazolin-7-yl)ox... von Haile, Pamela A, Casillas, Linda N, Votta, Bartholomew J, Wang, Gren Z, Charnley, Adam K, Dong, Xiaoyang, Bury, Michael J, Romano, Joseph J, Mehlmann, John F, King, Bryan W, Erhard, Karl F, Hanning, Charles R, Lipshutz, David B, Desai, Biva M, Capriotti, Carol A, Schaeffer, Michelle C, Berger, Scott B, Mahajan, Mukesh K, Reilly, Michael A, Nagilla, Rakesh, Rivera, Elizabeth J, Sun, Helen H, Kenna, John K, Beal, Allison M, Ouellette, Michael T, Kelly, Mike, Stemp, Gillian, Convery, Máire A, Vossenkämper, Anna, MacDonald, Thomas T, Gough, Peter J, Bertin, John, Marquis, Robert W

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Identification of Quinoline-Based RIP2 Kinase Inhibitors with an Improved Therapeutic Index to the hERG Ion Channel (vol 9, pg 1039, 2018) von Haile, Pamela A., Casillas, Linda N., Bury, Michael J., Mehlmann, John F., Singhaus, Robert, Charnley, Adam K., Hughes, Terry V., DeMartino, Michael P., Wang, Gren Z., Romano, Joseph J., Dong, Xiaoyang, Plotnikov, Nikolay V., Lakdawala, Ami S., Duraiswami, Chaya, Convery, Maire A., Votta, Bartholomew J., Lipshutz, David B., Desai, Biva M., Swift, Barbara, Capriotti, Carol A., Berger, Scott B., Mahajan, Mukesh K., Reilly, Michael A., Rivera, Elizabeth J., Sun, Helen H., Nagilla, Rakesh, LePage, Carol, Ouellette, Michael T., Totoritis, Rachel D., Donovan, Brian T., Brown, Barry S., Chaudhary, Khuram W., Gough, Peter J., Bertin, John, Marquis, Robert W.

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Identification and Characterization of Oxymetazoline Glucuronidation in Human Liver Microsomes: Evidence for the Involvement of UGT1 A9 von MAHAJAN, Mukesh K, UTTAMSINGH, Vinita, GAN, Liang-Shang, LEDUC, Barbara, WILLIAMS, David A

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Probabilistic seismic hazard map of NW Himalaya and its adjoining area, India von Mahajan, A. K., Thakur, V. C., Sharma, Mukat Lal, Chauhan, Mukesh

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Isolation and genetic characterization of canine adenovirus type 2 from a domestic dog showing neurological symptoms von Chander, Vishal, Sharma, G. K., Bhatt, Mukesh, Nandi, Sukdeb, Mahajan, S., Singh, Mithilesh, Mahendran, K., Karikalan, M., Pawde, Abhijit M., Gupta, Vikas, Singh, K. P., Rajak, K. K., Gupta, V. K., Singh, R. K.

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HETEROCYCLIC AMIDES AS KINASE INHIBITORS FOR USE IN THE TREATMENT CANCER von REILLY, Michael, MAHAJAN, Mukesh K, RATHI, Chetan, ANBARI, Jill Marinis

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A Study of Incidence of AKI in Critically Ill Patients von Paudel, Mukesh Sharma, Wig, Naveet, Mahajan, Sandeep, Pandey, Ravindra Mohan, Guleria, Randeep, Sharma, Surendra K.

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Shear Wave Velocity Investigation for Ten Representative Sites of National Capital Territory, New Delhi, India von Mahajan, A.K, Shukla, A.K, Pandey, Ajit, Chauhan, Mukesh, Chauhan, Neetu, Rai, Nitesh

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