RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer von Wang, Wei, Marinis, Jill M., Beal, Allison M., Savadkar, Shivraj, Wu, Yue, Khan, Mohammed, Taunk, Pardeep S., Wu, Nan, Su, Wenyu, Wu, Jingjing, Ahsan, Aarif, Kurz, Emma, Chen, Ting, Yaboh, Inedouye, Li, Fei, Gutierrez, Johana, Diskin, Brian, Hundeyin, Mautin, Reilly, Michael, Lich, John D., Harris, Philip A., Mahajan, Mukesh K., Thorpe, James H., Nassau, Pamela, Mosley, Julie E., Leinwand, Joshua, Kochen Rossi, Juan A., Mishra, Ankita, Aykut, Berk, Glacken, Michael, Ochi, Atsuo, Verma, Narendra, Kim, Jacqueline I., Vasudevaraja, Varshini, Adeegbe, Dennis, Almonte, Christina, Bagdatlioglu, Ece, Cohen, Deirdre J., Wong, Kwok-Kin, Bertin, John, Miller, George

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The Identification and Pharmacological Characterization of 6‑(tert-Butylsulfonyl)‑N‑(5-fluoro‑1H‑indazol-3-yl)quinolin-4-amine (GSK583), a Highly Potent and Selective Inhibitor of... von Haile, Pamela A, Votta, Bartholomew J, Marquis, Robert W, Bury, Michael J, Mehlmann, John F, Singhaus, Robert, Charnley, Adam K, Lakdawala, Ami S, Convery, Máire A, Lipshutz, David B, Desai, Biva M, Swift, Barbara, Capriotti, Carol A, Berger, Scott B, Mahajan, Mukesh K, Reilly, Michael A, Rivera, Elizabeth J, Sun, Helen H, Nagilla, Rakesh, Beal, Allison M, Finger, Joshua N, Cook, Michael N, King, Bryan W, Ouellette, Michael T, Totoritis, Rachel D, Pierdomenico, Maria, Negroni, Anna, Stronati, Laura, Cucchiara, Salvatore, Ziółkowski, Bartłomiej, Vossenkämper, Anna, MacDonald, Thomas T, Gough, Peter J, Bertin, John, Casillas, Linda N

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Directed Evolution Using Stabilized Bacterial Peptide Display von Navaratna, Tejas, Atangcho, Lydia, Mahajan, Mukesh, Subramanian, Vivekanandan, Case, Marshall, Min, Andrew, Tresnak, Daniel, Thurber, Greg M

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Allosteric control of dynamin-related protein 1 through a disordered C-terminal Short Linear Motif von Pérez-Jover, Isabel, Rochon, Kristy, Hu, Di, Mahajan, Mukesh, Madan Mohan, Pooja, Santos-Pérez, Isaac, Ormaetxea Gisasola, Julene, Martinez Galvez, Juan Manuel, Agirre, Jon, Qi, Xin, Mears, Jason A., Shnyrova, Anna V., Ramachandran, Rajesh

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Probing membrane enhanced protein-protein interactions in a minimal redox complex of cytochrome-P450 and P450-reductase von Mahajan, Mukesh, Ravula, Thirupathi, Prade, Elke, Anantharamaiah, G. M, Ramamoorthy, Ayyalusamy

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RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer von Wang, Wei, Marinis, Jill M., Beal, Allison M., Savadkar, Shivraj, Wu, Yue, Khan, Mohammed, Taunk, Pardeep S., Wu, Nan, Su, Wenyu, Wu, Jingjing, Ahsan, Aarif, Kurz, Emma, Chen, Ting, Yaboh, Inedouye, Li, Fei, Gutierrez, Johana, Diskin, Brian, Hundeyin, Mautin, Reilly, Michael, Lich, John D., Harris, Philip A., Mahajan, Mukesh K., Thorpe, James H., Nassau, Pamela, Mosley, Julie E., Leinwand, Joshua, Kochen Rossi, Juan A., Mishra, Ankita, Aykut, Berk, Glacken, Michael, Ochi, Atsuo, Verma, Narendra, Kim, Jacqueline I., Vasudevaraja, Varshini, Adeegbe, Dennis, Almonte, Christina, Bagdatlioglu, Ece, Cohen, Deirdre J., Wong, Kwok-Kin, Bertin, John, Miller, George

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Understanding Pharmacokinetic Disconnect in Preclinical Species for 4-Aminoquinolines: Consequences of Low Permeability and High P-glycoprotein Efflux Ratio on Rat and Dog Oral Pha... von Mahajan, Mukesh K., Rivera, Elizabeth J., Sun, Helen H., Nagilla, Rakesh, DeMartino, Michael P., Haile, Pamela A., Casillas, Linda N., Marquis, Robert W., Votta, Bartholomew J., Bertin, John, Reilly, Michael A.

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Kinetic and Structural Characterization of the Effects of Membrane on the Complex of Cytochrome b 5 and Cytochrome c von Gentry, Katherine A, Prade, Elke, Barnaba, Carlo, Zhang, Meng, Mahajan, Mukesh, Im, Sang-Choul, Anantharamaiah, G M, Nagao, Satoshi, Waskell, Lucy, Ramamoorthy, Ayyalusamy

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NMR structures and localization of the potential fusion peptides and the pre-transmembrane region of SARS-CoV: Implications in membrane fusion von Mahajan, Mukesh, Bhattacharjya, Surajit

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Identification of a RIP1 Kinase Inhibitor Clinical Candidate (GSK3145095) for the Treatment of Pancreatic Cancer von Harris, Philip A, Marinis, Jill M, Lich, John D, Berger, Scott B, Chirala, Anirudh, Cox, Julie A, Eidam, Patrick M, Finger, Joshua N, Gough, Peter J, Jeong, Jae U, Kang, James, Kasparcova, Viera, Leister, Lara K, Mahajan, Mukesh K, Miller, George, Nagilla, Rakesh, Ouellette, Michael T, Reilly, Michael A, Rendina, Alan R, Rivera, Elizabeth J, Sun, Helen H, Thorpe, James H, Totoritis, Rachel D, Wang, Wei, Wu, Dongling, Zhang, Daohua, Bertin, John, Marquis, Robert W

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Dual negative precursor ion scan approach for rapid detection of glutathione conjugates using liquid chromatography/tandem mass spectrometry von Mahajan, Mukesh K., Evans, Christopher A.

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Application of DMPK toolbox in predicting human pharmacokinetics for back-up RIP1 inhibitors: Learnings from GSK2982772 in clinic von Mahajan, Mukesh, Harris, Phil, Zhang, David, Richards-Peterson, Lauren, Thomas, Steven, Tompson, Debbie, Marinis, Jill, Berger, Scott, Marquis, Robert, Bertin, John, Reilly, Michael

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β-Hairpin Peptides: Heme Binding, Catalysis, and Structure in Detergent Micelles von Mahajan, Mukesh, Bhattacharjya, Surajit

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Designed Di-Heme Binding Helical Transmembrane Protein von Mahajan, Mukesh, Bhattacharjya, Surajit

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Identification and Characterization of Oxymetazoline Glucuronidation in Human Liver Microsomes: Evidence for the Involvement of UGT1A9 von Mahajan, Mukesh K., Uttamsingh, Vinita, Gan, Liang-Shang, Leduc, Barbara, Williams, David A.

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In Vitro Metabolism of Oxymetazoline: Evidence for Bioactivation to a Reactive Metabolite von MAHAJAN, Mukesh K, UTTAMSINGH, Vinita, DANIELS, J. Scott, GAN, Liang-Shang, LEDUC, Barbara W, WILLIAMS, David A

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Designed multi-stranded heme binding β-sheet peptides in membrane von D'Souza, Areetha, Mahajan, Mukesh, Bhattacharjya, Surajit

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NMR structure and localization of a large fragment of the SARS-CoV fusion protein: Implications in viral cell fusion von Mahajan, Mukesh, Chatterjee, Deepak, Bhuvaneswari, Kannaian, Pillay, Shubhadra, Bhattacharjya, Surajit

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[beta]-Hairpin Peptides: Heme Binding, Catalysis, and Structure in Detergent Micelles von Mahajan, Mukesh, Bhattacharjya, Surajit

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Corrigendum: Designed Di-Heme Binding Helical Transmembrane Protein von Mahajan, Mukesh, Bhattacharjya, Surajit

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