Discovery of Potent and Selective Pyrazolopyrimidine Janus Kinase 2 Inhibitors von Hanan, Emily J, van Abbema, Anne, Barrett, Kathy, Blair, Wade S, Blaney, Jeff, Chang, Christine, Eigenbrot, Charles, Flynn, Sean, Gibbons, Paul, Hurley, Christopher A, Kenny, Jane R, Kulagowski, Janusz, Lee, Leslie, Magnuson, Steven R, Morris, Claire, Murray, Jeremy, Pastor, Richard M, Rawson, Tom, Siu, Michael, Ultsch, Mark, Zhou, Aihe, Sampath, Deepak, Lyssikatos, Joseph P

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Inhibition of bromodomain-containing protein 9 for the prevention of epigenetically-defined drug resistance von Crawford, Terry D., Vartanian, Steffan, Côté, Alexandre, Bellon, Steve, Duplessis, Martin, Flynn, E. Megan, Hewitt, Michael, Huang, Hon-Ren, Kiefer, James R., Murray, Jeremy, Nasveschuk, Christopher G., Pardo, Eneida, Romero, F. Anthony, Sandy, Peter, Tang, Yong, Taylor, Alexander M., Tsui, Vickie, Wang, Jian, Wang, Shumei, Zawadzke, Laura, Albrecht, Brian K., Magnuson, Steven R., Cochran, Andrea G., Stokoe, David

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Discovery of Selective 4‑Amino-pyridopyrimidine Inhibitors of MAP4K4 Using Fragment-Based Lead Identification and Optimization von Crawford, Terry D, Ndubaku, Chudi O, Chen, Huifen, Boggs, Jason W, Bravo, Brandon J, DeLaTorre, Kelly, Giannetti, Anthony M, Gould, Stephen E, Harris, Seth F, Magnuson, Steven R, McNamara, Erin, Murray, Lesley J, Nonomiya, Jim, Sambrone, Amy, Schmidt, Stephen, Smyczek, Tanya, Stanley, Mark, Vitorino, Philip, Wang, Lan, West, Kristina, Wu, Ping, Ye, Weilan

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Diving into the Water: Inducible Binding Conformations for BRD4, TAF1(2), BRD9, and CECR2 Bromodomains von Crawford, Terry D, Tsui, Vickie, Flynn, E. Megan, Wang, Shumei, Taylor, Alexander M, Côté, Alexandre, Audia, James E, Beresini, Maureen H, Burdick, Daniel J, Cummings, Richard, Dakin, Les A, Duplessis, Martin, Good, Andrew C, Hewitt, Michael C, Huang, Hon-Ren, Jayaram, Hariharan, Kiefer, James R, Jiang, Ying, Murray, Jeremy, Nasveschuk, Christopher G, Pardo, Eneida, Poy, Florence, Romero, F. Anthony, Tang, Yong, Wang, Jian, Xu, Zhaowu, Zawadzke, Laura E, Zhu, Xiaoyu, Albrecht, Brian K, Magnuson, Steven R, Bellon, Steve, Cochran, Andrea G

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GNE-064: A Potent, Selective, and Orally Bioavailable Chemical Probe for the Bromodomains of SMARCA2 and SMARCA4 and the Fifth Bromodomain of PBRM1 von Taylor, Alexander M., Bailey, Chris, Belmont, Lisa D., Campbell, Robert, Cantone, Nico, Côté, Alexandre, Crawford, Terry D., Cummings, Richard, DeMent, Kevin, Duplessis, Martin, Flynn, Megan, Good, Andrew C., Huang, Hon-Ren, Joshi, Shivangi, Leblanc, Yves, Murray, Jeremy, Nasveschuk, Christopher G., Neiss, Adrianne, Poy, Florence, Romero, F. Anthony, Sandy, Peter, Tang, Yong, Tsui, Vickie, Zawadzke, Laura, Sims, Robert J., Audia, James E., Bellon, Steven F., Magnuson, Steven R., Albrecht, Brian K., Cochran, Andrea G.

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Regulatory T Cell Modulation by CBP/EP300 Bromodomain Inhibition von Ghosh, Srimoyee, Taylor, Alexander, Chin, Melissa, Huang, Hon-Ren, Conery, Andrew R., Mertz, Jennifer A., Salmeron, Andres, Dakle, Pranal J., Mele, Deanna, Cote, Alexandre, Jayaram, Hari, Setser, Jeremy W., Poy, Florence, Hatzivassiliou, Georgia, DeAlmeida-Nagata, Denise, Sandy, Peter, Hatton, Charlie, Romero, F. Anthony, Chiang, Eugene, Reimer, Thornik, Crawford, Terry, Pardo, Eneida, Watson, Venita G., Tsui, Vickie, Cochran, Andrea G., Zawadzke, Laura, Harmange, Jean-Christophe, Audia, James E., Bryant, Barbara M., Cummings, Richard T., Magnuson, Steven R., Grogan, Jane L., Bellon, Steve F., Albrecht, Brian K., Sims, Robert J., Lora, Jose M.

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GNE-371, a Potent and Selective Chemical Probe for the Second Bromodomains of Human Transcription-Initiation-Factor TFIID Subunit 1 and Transcription-Initiation-Factor TFIID Subuni... von Wang, Shumei, Tsui, Vickie, Crawford, Terry D, Audia, James E, Burdick, Daniel J, Beresini, Maureen H, Côté, Alexandre, Cummings, Richard, Duplessis, Martin, Flynn, E. Megan, Hewitt, Michael C, Huang, Hon-Ren, Jayaram, Hariharan, Jiang, Ying, Joshi, Shivangi, Murray, Jeremy, Nasveschuk, Christopher G, Pardo, Eneida, Poy, Florence, Romero, F. Anthony, Tang, Yong, Taylor, Alexander M, Wang, Jian, Xu, Zhaowu, Zawadzke, Laura E, Zhu, Xiaoyu, Albrecht, Brian K, Magnuson, Steven R, Bellon, Steve, Cochran, Andrea G

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Two-directional synthesis and its use in natural product synthesis von Magnuson, Steven R.

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Fragment-based identification and optimization of a class of potent pyrrolo[2,1-f][1,2,4]triazine MAP4K4 inhibitors von Wang, Lan, Stanley, Mark, Boggs, Jason W., Crawford, Terry D., Bravo, Brandon J., Giannetti, Anthony M., Harris, Seth F., Magnuson, Steven R., Nonomiya, Jim, Schmidt, Stephen, Wu, Ping, Ye, Weilan, Gould, Stephen E., Murray, Lesley J., Ndubaku, Chudi O., Chen, Huifen

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A Concise Total Synthesis of Dysidiolide through Application of a Dioxolenium-Mediated Diels−Alder Reaction von Magnuson, Steven R, Sepp-Lorenzino, Laura, Rosen, Neal, Danishefsky, Samuel J

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GNE-886: A Potent and Selective Inhibitor of the Cat Eye Syndrome Chromosome Region Candidate 2 Bromodomain (CECR2) von Crawford, Terry D, Audia, James E, Bellon, Steve, Burdick, Daniel J, Bommi-Reddy, Archana, Côté, Alexandre, Cummings, Richard T, Duplessis, Martin, Flynn, E. Megan, Hewitt, Michael, Huang, Hon-Ren, Jayaram, Hariharan, Jiang, Ying, Joshi, Shivangi, Kiefer, James R, Murray, Jeremy, Nasveschuk, Christopher G, Neiss, Arianne, Pardo, Eneida, Romero, F. Anthony, Sandy, Peter, Tang, Yong, Taylor, Alexander M, Tsui, Vickie, Wang, Jian, Wang, Shumei, Wang, Yongyun, Xu, Zhaowu, Zawadzke, Laura, Zhu, Xiaoqin, Albrecht, Brian K, Magnuson, Steven R, Cochran, Andrea G

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Efficient syntheses of 2-fluoroalkylbenzimidazoles and -benzothiazoles von René, Olivier, Souverneva, Alexandra, Magnuson, Steven R., Fauber, Benjamin P.

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Cyclopentannulation by an Iterative Process of Sequential Claisen Rearrangement and Enyne Radical Closure:  Routes to Triquinane and Propellane Systems and Use in the Synthesis of... von Clive, D. L. J, Magnuson, Steven R, Manning, Hartford W, Mayhew, Darrin L

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Fragment-based identification and optimization of a class of potent pyrrolo[2,1-f][1,2,4]triazine MAP4K4 inhibitors von Wang, Lan, Stanley, Mark, Boggs, Jason W., Crawford, Terry D., Bravo, Brandon J., Giannetti, Anthony M., Harris, Seth F., Magnuson, Steven R., Nonomiya, Jim, Schmidt, Stephen, Wu, Ping, Ye, Weilan, Gould, Stephen E., Murray, Lesley J., Ndubaku, Chudi O., Chen, Huifen

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ChemInform Abstract: Efficient Syntheses of 2-Fluoroalkylbenzimidazoles and -benzothiazoles von Rene, Olivier, Souverneva, Alexandra, Magnuson, Steven R., Fauber, Benjamin P.

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Synthesis of the sesquiterpene (±)-ceratopicanol: Use of radicals derived from epoxides von Clive, Derrick L.J., Magnuson, Steven R.

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THERAPEUTIC PYRIDAZINE COMPOUNDS AND USES THEREOF von CRAWFORD, Terry, GOOD, Andrew, Charles, TAYLOR, Alexander, M, ALBRECHT, Brian, K, DUPLESSIS, Martin, NASVESCHUK, Christopher, G, MAGNUSON, Steven, R, COTE, Alexandre, LEBLANC, Yves, ROMERO, F. Anthony, TANG, Yong

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PYRAZOLOPYRIMIDINE JAK INHIBITOR COMPOUNDS AND METHODS von Hanan, Emily, Lyssikatos, Joseph, Hurley, Christopher, Magnuson, Steven R, Zhou, Aihe, Zak, Mark E, Liu, Wendy, Rawson, Thomas E, Gibbons, Paul, Mendonca, Rohan, Pastor, Richard, Zhu, Bing-Yan, Siu, Michael

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AMINOQUINAZOLINE AND PYRIDOPYRIMIDINE DERIVATIVES von CHEN, Huifen, CRAWFORD, Terry, HARRIS, Seth F, MAGNUSON, Steven, R, NDUBAKU, Chudi, WANG, Lan

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PYRAZOLOPYRIMIDINE JAK INHIBITOR COMPOUNDS AND METHODS von Hanan, Emily, Hurley, Christopher, Magnuson, Steven R, Zhou, Aihe, Zak, Mark E, Lyssikatos, Joseph P, Liu, Wendy, Rawson, Thomas E, Gibbons, Paul, Mendonca, Rohan, Pastor, Richard, Zhu, Bing-Yan, Siu, Michael

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