Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope von Cole, David K, Fuller, Anna, Dolton, Garry, Zervoudi, Efthalia, Legut, Mateusz, Miles, Kim, Blanchfield, Lori, Madura, Florian, Holland, Christopher J, Bulek, Anna M, Bridgeman, John S, Miles, John J, Schauenburg, Andrea J A, Beck, Konrad, Evavold, Brian D, Rizkallah, Pierre J, Sewell, Andrew K

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Molecular Rules Underpinning Enhanced Affinity Binding of Human T Cell Receptors Engineered for Immunotherapy von Crean, Rory M., MacLachlan, Bruce J., Madura, Florian, Whalley, Thomas, Rizkallah, Pierre J., Holland, Christopher J., McMurran, Catriona, Harper, Stephen, Godkin, Andrew, Sewell, Andrew K., Pudney, Christopher R., van der Kamp, Marc W., Cole, David K.

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Structural basis for the killing of human beta cells by CD8+ T cells in type 1 diabetes von Bulek, Anna M, Cole, David K, Skowera, Ania, Dolton, Garry, Gras, Stephanie, Madura, Florian, Fuller, Anna, Miles, John J, Gostick, Emma, Price, David A, Drijfhout, Jan W, Knight, Robin R, Huang, Guo C, Lissin, Nikolai, Molloy, Peter E, Wooldridge, Linda, Jakobsen, Bent K, Rossjohn, Jamie, Peakman, Mark, Rizkallah, Pierre J, Sewell, Andrew K

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TCR‐induced alteration of primary MHC peptide anchor residue von Madura, Florian, Rizkallah, Pierre J., Legut, Mateusz, Holland, Christopher J., Fuller, Anna, Bulek, Anna, Schauenburg, Andrea J., Trimby, Andrew, Hopkins, Jade R., Wells, Stephen A., Godkin, Andrew, Miles, John J., Sami, Malkit, Li, Yi, Liddy, Nathaniel, Jakobsen, Bent K., Loveridge, E. Joel, Cole, David K., Sewell, Andrew K.

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Structural basis for ineffective T‐cell responses to MHC anchor residue‐improved “heteroclitic” peptides von Madura, Florian, Rizkallah, Pierre J., Holland, Christopher J., Fuller, Anna, Bulek, Anna, Godkin, Andrew J., Schauenburg, Andrea J., Cole, David K., Sewell, Andrew K.

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T-cell Receptor (TCR)-Peptide Specificity Overrides Affinity-enhancing TCR-Major Histocompatibility Complex Interactions von Cole, David K., Miles, Kim M., Madura, Florian, Holland, Christopher J., Schauenburg, Andrea J.A., Godkin, Andrew J., Bulek, Anna M., Fuller, Anna, Akpovwa, Hephzibah J.E., Pymm, Phillip G., Liddy, Nathaniel, Sami, Malkit, Li, Yi, Rizkallah, Pierre J., Jakobsen, Bent K., Sewell, Andrew K.

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Enhanced Detection of Antigen-Specific CD4+ T Cells Using Altered Peptide Flanking Residue Peptide-MHC Class II Multimers von Holland, Christopher J, Dolton, Garry, Scurr, Martin, Ladell, Kristin, Schauenburg, Andrea J, Miners, Kelly, Madura, Florian, Sewell, Andrew K, Price, David A, Cole, David K, Godkin, Andrew J

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T-cell Receptor Specificity Maintained by Altered Thermodynamics von Madura, Florian, Rizkallah, Pierre J., Miles, Kim M., Holland, Christopher J., Bulek, Anna M., Fuller, Anna, Schauenburg, Andrea J.A., Miles, John J., Liddy, Nathaniel, Sami, Malkit, Li, Yi, Hossain, Moushumi, Baker, Brian M., Jakobsen, Bent K., Sewell, Andrew K., Cole, David K.

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T-cell Receptor-optimized Peptide Skewing of the T-cell Repertoire Can Enhance Antigen Targeting von Ekeruche-Makinde, Julia, Clement, Mathew, Cole, David K., Edwards, Emily S.J., Ladell, Kristin, Miles, John J., Matthews, Katherine K., Fuller, Anna, Lloyd, Katy A., Madura, Florian, Dolton, Garry M., Pentier, Johanne, Lissina, Anna, Gostick, Emma, Baxter, Tiffany K., Baker, Brian M., Rizkallah, Pierre J., Price, David A., Wooldridge, Linda, Sewell, Andrew K.

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Real time detection of peptide–MHC dissociation reveals that improvement of primary MHC-binding residues can have a minimal, or no, effect on stability von Miles, Kim M., Miles, John J., Madura, Florian, Sewell, Andrew K., Cole, David K.

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TCR/pMHC Optimized Protein crystallization Screen von Bulek, Anna M., Madura, Florian, Fuller, Anna, Holland, Christopher J., Schauenburg, Andrea J.A., Sewell, Andrew K., Rizkallah, Pierre J., Cole, David K.

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Minimal conformational plasticity enables TCR cross-reactivity to different MHC class II heterodimers von Holland, Christopher J., Rizkallah, Pierre J., Vollers, Sabrina, Calvo-Calle, J. Mauricio, Madura, Florian, Fuller, Anna, Sewell, Andrew K., Stern, Lawrence J., Godkin, Andrew, Cole, David K.

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T-cell Receptor Specificity Maintained by Altered Thermodynamics<inline-graphic xlink:href="sbox.jpg"/> von Madura, Florian, Rizkallah, Pierre J, Miles, Kim M, Holland, Christopher J, Bulek, Anna M, Fuller, Anna, Schauenburg, Andrea JA, Miles, John J, Liddy, Nathaniel, Sami, Malkit, Li, Yi, Hossain, Moushumi, Baker, Brian M, Jakobsen, Bent K, Sewell, Andrew K, Cole, David K

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Structural basis for the killing of human beta cells by [CD8.sup.+] T cells in type 1 diabetes von Bulek, Anna M, Cole, David K, Skowera, Ania, Dolton, Garry, Gras, Stephanie, Madura, Florian, Fuller, Anna, Miles, John J, Gostick, Emma, Price, David A, Drijfhout, Jan W, Knight, Robin R, Huang, Guo C, Lissin, Nikolai, Molloy, Peter E, Wooldridge, Linda, Jakobsen, Bent K, Rossjohn, Jamie, Peakman, Mark, Rizkallah, Pierre J, Sewell, Andrew K

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Structural basis for the killing of human beta cells by CD8 super(+) T cells in type 1 diabetes von Bulek, Anna M, Cole, David K, Skowera, Ania, Dolton, Garry, Gras, Stephanie, Madura, Florian, Fuller, Anna, Miles, John J, Gostick, Emma, Price, David A, Drijfhout, Jan W, Knight, Robin R, Huang, Guo C, Lissin, Nikolai, Molloy, Peter E, Wooldridge, Linda, Jakobsen, Bent K, Rossjohn, Jamie, Peakman, Mark, Rizkallah, Pierre J, Sewell, Andrew K

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Structural basis of human β-cell killing by CD8+ T cells in Type 1 diabetes von Bulek, Anna M., Cole, David K., Skowera, Ania, Dolton, Garry, Gras, Stephanie, Madura, Florian, Fuller, Anna, Miles, John J., Gostick, Emma, Price, David A., Drijfhout, Jan W., Knight, Robin R., Huang, Guo C., Lissin, Nikolai, Molloy, Peter E., Wooldridge, Linda, Jakobsen, Bent K., Rossjohn, Jamie, Peakman, Mark, Rizkallah, Pierre J., Sewell, Andrew K.

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METHOD FOR THE PRODUCTION AND PURIFICATION OF MULTIVALENT IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS von Borsali, Chakib, Letestu, Sonia, Van Horen, Ellen, Brigé, Ann, Madura, Florian, Merchiers, Tom

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METHOD FOR THE PRODUCTION AND PURIFICATION OF MULTIVALENT IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS von BRIGÉ, Ann, BORSALI, Chakib, VAN HOREN, Ellen, LETESTU, Sonia, MERCHIERS, Tom, MADURA, Florian

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Method for the production and purification of multivalent immunoglobulin single variable domains von BRIGÉ, Ann, BORSALI, Chakib, VAN HOREN, Ellen, LETESTU, Sonia, MERCHIERS, Tom, MADURA, Florian

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METHOD FOR THE PRODUCTION AND PURIFICATION OF MULTIVALENT IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS von BRIGÉ, Ann, BORSALI, Chakib, VAN HOREN, Ellen, LETESTU, Sonia, MERCHIERS, Tom, MADURA, Florian

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