High systemic and tumor-associated IL-8 correlates with reduced clinical benefit of PD-L1 blockade von Yuen, Kobe C., Liu, Li-Fen, Gupta, Vinita, Madireddi, Shravan, Keerthivasan, Shilpa, Li, Congfen, Rishipathak, Deepali, Williams, Patrick, Kadel, Edward E., Koeppen, Hartmut, Chen, Ying-Jiun, Modrusan, Zora, Grogan, Jane L., Banchereau, Romain, Leng, Ning, Thastrom, AnnChristine, Shen, Xiadong, Hashimoto, Kenji, Tayama, Darren, van der Heijden, Michiel S., Rosenberg, Jonathan E., McDermott, David F., Powles, Thomas, Hegde, Priti S., Huseni, Mahrukh A., Mariathasan, Sanjeev

Volltext

TNF superfamily in inflammatory disease: translating basic insights von Croft, Michael, Duan, Wei, Choi, Heonsik, Eun, So-Young, Madireddi, Shravan, Mehta, Amit

Volltext

Galectin-9 controls the therapeutic activity of 4-1BB-targeting antibodies von Madireddi, Shravan, Eun, So-Young, Lee, Seung-Woo, Nemčovičová, Ivana, Mehta, Amit Kumar, Zajonc, Dirk M, Nishi, Nozomu, Niki, Toshiro, Hirashima, Mitsuomi, Croft, Michael

Volltext

Regulatory T Cell-Mediated Suppression of Inflammation Induced by DR3 Signaling Is Dependent on Galectin-9 von Madireddi, Shravan, Eun, So-Young, Mehta, Amit K, Birta, Aruna, Zajonc, Dirk M, Niki, Toshiro, Hirashima, Mitsuomi, Podack, Eckhard R, Schreiber, Taylor H, Croft, Michael

Volltext

Intratumoral CD103+ CD8+ T cells predict response to PD-L1 blockade von Banchereau, Romain, Chitre, Avantika S., Scherl, Alexis, Wu, Thomas D., Patil, Namrata S., de Almeida, Patricia, Kadel, III, Edward E., Madireddi, Shravan, Au-Yeung, Amelia, Takahashi, Chikara, Chen, Ying-Jiun, Modrusan, Zora, McBride, Jacqueline, Nersesian, Rhea, El-Gabry, Ehab A., Robida, Mark D., Hung, Jeffrey C., Kowanetz, Marcin, Zou, Wei, McCleland, Mark, Caplazi, Patrick, Eshgi, Shadi Toghi, Koeppen, Hartmut, Hegde, Priti S., Mellman, Ira, Mathews, W. Rodney, Powles, Thomas, Mariathasan, Sanjeev, Grogan, Jane, O'Gorman, William E

Volltext

Author Correction: High systemic and tumor-associated IL-8 correlates with reduced clinical benefit of PD-L1 blockade von Yuen, Kobe C., Liu, Li-Fen, Gupta, Vinita, Madireddi, Shravan, Keerthivasan, Shilpa, Li, Congfen, Rishipathak, Deepali, Williams, Patrick, Kadel, Edward E., Koeppen, Hartmut, Chen, Ying-Jiun, Modrusan, Zora, Grogan, Jane L., Banchereau, Romain, Leng, Ning, Thastrom, AnnChristine, Shen, Xiadong, Hashimoto, Kenji, Tayama, Darren, van der Heijden, Michiel S., Rosenberg, Jonathan E., McDermott, David F., Powles, Thomas, Hegde, Priti S., Huseni, Mahrukh A., Mariathasan, Sanjeev

Volltext

Cutting edge: 4-1BB controls regulatory activity in dendritic cells through promoting optimal expression of retinal dehydrogenase von Lee, Seung-Woo, Park, Yunji, Eun, So-Young, Madireddi, Shravan, Cheroutre, Hilde, Croft, Michael

Volltext

SA-4-1BBL costimulation inhibits conversion of conventional CD4+ T cells into CD4+ FoxP3+ T regulatory cells by production of IFN-γ von Madireddi, Shravan, Schabowsky, Rich-Henry, Srivastava, Abhishek K, Sharma, Rajesh K, Yolcu, Esma S, Shirwan, Haval

Volltext

4-1BB Ligand as an Effective Multifunctional Immunomodulator and Antigen Delivery Vehicle for the Development of Therapeutic Cancer Vaccines von SHARMA, Rajesh K, SCHABOWSKY, Rich-Henry, SHIRWAN, Haval, SRIVASTAVA, Abhishek K, ELPEK, Kutlu G, MADIREDD, Shravan, HONG ZHAO, ZHENPING ZHONG, MILLER, Robert W, MACLEOD, Kathryn J, YOLCU, Esma S

Volltext

Peripheral T cell expansion predicts tumour infiltration and clinical response von Wu, Thomas D., Madireddi, Shravan, de Almeida, Patricia E., Banchereau, Romain, Chen, Ying-Jiun J., Chitre, Avantika S., Chiang, Eugene Y., Iftikhar, Hina, O’Gorman, William E., Au-Yeung, Amelia, Takahashi, Chikara, Goldstein, Leonard D., Poon, Chungkee, Keerthivasan, Shilpa, de Almeida Nagata, Denise E., Du, Xiangnan, Lee, Hyang-Mi, Banta, Karl L., Mariathasan, Sanjeev, Das Thakur, Meghna, Huseni, Mahrukh A., Ballinger, Marcus, Estay, Ivette, Caplazi, Patrick, Modrusan, Zora, Delamarre, Lélia, Mellman, Ira, Bourgon, Richard, Grogan, Jane L.

Volltext

Homeostatic functions of monocytes and interstitial lung macrophages are regulated via collagen domain-binding receptor LAIR1 von Keerthivasan, Shilpa, Şenbabaoğlu, Yasin, Martinez-Martin, Nadia, Husain, Bushra, Verschueren, Erik, Wong, Anne, Yang, Yeqing Angela, Sun, Yonglian, Pham, Victoria, Hinkle, Trent, Oei, Yoko, Madireddi, Shravan, Corpuz, Racquel, Tam, Lucinda, Carlisle, Samantha, Roose-Girma, Merone, Modrusan, Zora, Ye, Zhengmao, Koerber, James T., Turley, Shannon J.

Volltext

High-efficiency nonviral CRISPR/Cas9-mediated gene editing of human T cells using plasmid donor DNA von Oh, Soyoung A, Senger, Kate, Madireddi, Shravan, Akhmetzyanova, Ilseyar, Ishizuka, Isabel E, Tarighat, Somayeh, Lo, Jerry H, Shaw, David, Haley, Benjamin, Rutz, Sascha

Volltext

CD8+ T cell-intrinsic IL-6 signaling promotes resistance to anti-PD-L1 immunotherapy von Huseni, Mahrukh A., Wang, Lifen, Klementowicz, Joanna E., Yuen, Kobe, Breart, Beatrice, Orr, Christine, Liu, Li-fen, Li, Yijin, Gupta, Vinita, Li, Congfen, Rishipathak, Deepali, Peng, Jing, Şenbabaoǧlu, Yasin, Modrusan, Zora, Keerthivasan, Shilpa, Madireddi, Shravan, Chen, Ying-Jiun, Fraser, Eleanor J., Leng, Ning, Hamidi, Habib, Koeppen, Hartmut, Ziai, James, Hashimoto, Kenji, Fassò, Marcella, Williams, Patrick, McDermott, David F., Rosenberg, Jonathan E., Powles, Thomas, Emens, Leisha A., Hegde, Priti S., Mellman, Ira, Turley, Shannon J., Wilson, Mark S., Mariathasan, Sanjeev, Molinero, Luciana, Merchant, Mark, West, Nathaniel R.

Volltext

Abstract 2000: Systemic and tumor associated IL-8 correlates with resistance to PD-L1 blockade von Yuen, Kobe, Liu, Lifen, Li, Congfen, Rishipathak, Deepali, Williams, Patrick, Kadel, Edward, Koeppen, Hartmut, Madireddi, Shravan, Keerthivasan, Shilpa, Chen, Ying-Jun, Modrusen, Zora, Banchereau, Romain, Leng, Ning, Hegde, Priti, Huseni, Mahrukh, Mariathasan, Sanjeev

Volltext

In silico tools for accurate HLA and KIR inference from clinical sequencing data empower immunogenetics on individual-patient and population scales von Chen, Jieming, Madireddi, Shravan, Nagarkar, Deepti, Migdal, Maciej, Vander Heiden, Jason, Chang, Diana, Mukhyala, Kiran, Selvaraj, Suresh, Kadel, Edward E, Brauer, Matthew J, Mariathasan, Sanjeev, Hunkapiller, Julie, Jhunjhunwala, Suchit, Albert, Matthew L, Hammer, Christian

Volltext

High systemic and tumor-associated IL8 correlates with reduced clinical benefit of PD-L1 blockade von Yuen, Kobe C., Liu, Lifen, Gupta, Vinita, Madireddi, Shravan, Keerthivasan, Shilpa, Li, Congfen, Rishipathak, Deepali, Williams, Patrick, Kadel, Edward E., Koeppen, Hartmut, Chen, Ying-Jiun, Modrusan, Zora, Grogan, Jane L., Banchereau, Romain, Leng, Ning, Thastrom, AnnChristine, Shen, Xiadong, Hashimoto, Kenji, Tayama, Darren, van der Heijden, Michiel S., Rosenberg, Jonathan E., McDermott, David F., Powles, Thomas, Hegde, Priti S., Huseni, Mahrukh A., Mariathasan, Sanjeev

Volltext

Treg-mediated Suppression of Inflammation Induced by DR3 Signaling is Dependent on Galectin-9 von Madireddi, Shravan, Eun, So-Young, Mehta, Amit K., Birta, Aruna, Zajonc, Dirk M, Niki, Toshiro, Hirashima, Mitsuomi, Podack, Eckhard R., Schreiber, Taylor H., Croft, Michael

Volltext

Tetravalent biepitopic targeting enables intrinsic antibody agonism of tumor necrosis factor receptor superfamily members von Yang, Yanli, Yeh, Sherry H, Madireddi, Shravan, Matochko, Wadim L, Gu, Chen, Pacheco Sanchez, Patricia, Ultsch, Mark, De Leon Boenig, Gladys, Harris, Seth F, Leonard, Brandon, Scales, Suzie J, Zhu, Jing W, Christensen, Erin, Hang, Julie Q, Brezski, Randall J, Marsters, Scot, Ashkenazi, Avi, Sukumaran, Siddharth, Chiu, Henry, Cubas, Rafael, Kim, Jeong M, Lazar, Greg A

Volltext

Galectin-9 Controls the Activity of DR3 (TNFRSF25) in Suppressing Immunity von Madireddi, Shravan, Eun, So-Young, Mehta, Amit K, Birta, Aruna, Zajonc, Dirk M, Nishi, Nozomu, Niki, Toshiro, Hirashima, Mitsuomi, Schreiber, Taylor H, Podack, Eckhard R, Croft, Michael

Volltext

Abstract PO084: Patterns of T cell clonal expansion in cancer patients associate with response to immunotherapy von Madireddi, Shravan, Wu, Thomas D., de Almeida, Patricia E., Banchereau, Romain, Chen, Ying-Jiun J., Chitre, Avantika S., Iftikhar, Hina, O'Gorman, William E., Au-Yeung, Amelia, Takahashi, Chikara, Goldstein, Leonard D., Poon, Chungkee, Keerthivasan, Shilpa, Mariathasan, Sanjeev, Das Thakur, Meghna, Huseni, Mahrukh A., Ballinger, Marcus, Estay, Ivette, Caplazi, Patrick, Modrusan, Zora, Delamarre, Lélia, Mellman, Ira, Bourgon, Richard, Grogan, Jane L.

Volltext