The mitochondrial Na+/Ca2+ exchanger is essential for Ca2+ homeostasis and viability von Luongo, Timothy S., Lambert, Jonathan P., Gross, Polina, Nwokedi, Mary, Lombardi, Alyssa A., Shanmughapriya, Santhanam, Carpenter, April C., Kolmetzky, Devin, Gao, Erhe, van Berlo, Jop H., Tsai, Emily J., Molkentin, Jeffery D., Chen, Xiongwen, Madesh, Muniswamy, Houser, Steven R., Elrod, John W.

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Loss of Adult Cardiac Myocyte GSK-3 Leads to Mitotic Catastrophe Resulting in Fatal Dilated Cardiomyopathy von Zhou, Jibin, Ahmad, Firdos, Parikh, Shan, Hoffman, Nichole E, Rajan, Sudarsan, Verma, Vipin K, Song, Jianliang, Yuan, Ancai, Shanmughapriya, Santhanam, Guo, Yuanjun, Gao, Erhe, Koch, Walter, Woodgett, James R, Madesh, Muniswamy, Kishore, Raj, Lal, Hind, Force, Thomas

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Lactate Elicits ER-Mitochondrial Mg2+ Dynamics to Integrate Cellular Metabolism von Daw, Cassidy C., Ramachandran, Karthik, Enslow, Benjamin T., Maity, Soumya, Bursic, Brian, Novello, Matthew J., Rubannelsonkumar, Cherubina S., Mashal, Ayah H., Ravichandran, Joel, Bakewell, Terry M., Wang, Weiwei, Li, Kang, Madaris, Travis R., Shannon, Christopher E., Norton, Luke, Kandala, Soundarya, Caplan, Jeffrey, Srikantan, Subramanya, Stathopulos, Peter B., Reeves, W. Brian, Madesh, Muniswamy

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Mitochondrial Reactive Oxygen Species Mediate Lysophosphatidylcholine-Induced Endothelial Cell Activation von Li, Xinyuan, Fang, Pu, Li, Yafeng, Kuo, Yin-Ming, Andrews, Andrew J, Nanayakkara, Gayani, Johnson, Candice, Fu, Hangfei, Shan, Huimin, Du, Fuyong, Hoffman, Nicholas E, Yu, Daohai, Eguchi, Satoru, Madesh, Muniswamy, Koch, Walter J, Sun, Jianxin, Jiang, Xiaohua, Wang, Hong, Yang, Xiaofeng

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The Mitochondrial Calcium Uniporter Matches Energetic Supply with Cardiac Workload during Stress and Modulates Permeability Transition von Luongo, Timothy S., Lambert, Jonathan P., Yuan, Ancai, Zhang, Xueqian, Gross, Polina, Song, Jianliang, Shanmughapriya, Santhanam, Gao, Erhe, Jain, Mohit, Houser, Steven R., Koch, Walter J., Cheung, Joseph Y., Madesh, Muniswamy, Elrod, John W.

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Isoform- and Species-specific Control of Inositol 1,4,5-Trisphosphate (IP3) Receptors by Reactive Oxygen Species von Bánsághi, Száva, Golenár, Tünde, Madesh, Muniswamy, Csordás, György, RamachandraRao, Satish, Sharma, Kumar, Yule, David I., Joseph, Suresh K., Hajnóczky, György

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Bone-Derived Stem Cells Repair the Heart After Myocardial Infarction Through Transdifferentiation and Paracrine Signaling Mechanisms von Duran, Jason M., Makarewich, Catherine A., Sharp, Thomas E., Starosta, Timothy, Zhu, Fang, Hoffman, Nicholas E., Chiba, Yumi, Madesh, Muniswamy, Berretta, Remus M., Kubo, Hajime, Houser, Steven R.

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Simultaneous detection of apoptosis and mitochondrial superoxide production in live cells by flow cytometry and confocal microscopy von Pacher, Pál, Mukhopadhyay, Partha, Rajesh, Mohanraj, Haskó, György, Hawkins, Brian J, Madesh, Muniswamy

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SPG7 Is an Essential and Conserved Component of the Mitochondrial Permeability Transition Pore von Shanmughapriya, Santhanam, Rajan, Sudarsan, Hoffman, Nicholas E., Higgins, Andrew M., Tomar, Dhanendra, Nemani, Neeharika, Hines, Kevin J., Smith, Dylan J., Eguchi, Akito, Vallem, Sandhya, Shaikh, Farah, Cheung, Maggie, Leonard, Nicole J., Stolakis, Ryan S., Wolfers, Matthew P., Ibetti, Jessica, Chuprun, J. Kurt, Jog, Neelakshi R., Houser, Steven R., Koch, Walter J., Elrod, John W., Madesh, Muniswamy

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The human ion channel TRPM2 modulates neuroblastoma cell survival and mitochondrial function through Pyk2, CREB, and MCU activation von Hirschler-Laszkiewicz, Iwona, Chen, Shu-Jen, Bao, Lei, Wang, JuFang, Zhang, Xue-Qian, Shanmughapriya, Santhanam, Keefer, Kerry, Madesh, Muniswamy, Cheung, Joseph Y, Miller, Barbara A

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Mitochondrial calcium uptake orchestrates vertebrate pigmentation via transcriptional regulation of keratin filaments von Tanwar, Jyoti, Ahuja, Kriti, Sharma, Akshay, Sehgal, Paras, Ranjan, Gyan, Sultan, Farina, Agrawal, Anushka, D'Angelo, Donato, Priya, Anshu, Yenamandra, Vamsi K, Singh, Archana, Raffaello, Anna, Madesh, Muniswamy, Rizzuto, Rosario, Sivasubbu, Sridhar, Motiani, Rajender K

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The mitochondrial Ca2+ uniporter channel synergizes with fluid shear stress to induce mitochondrial Ca2+ oscillations von Patel, Akshar, Simkulet, Matthew, Maity, Soumya, Venkatesan, Manigandan, Matzavinos, Anastasios, Madesh, Muniswamy, Alevriadou, B. Rita

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VDAC-Dependent Permeabilization of the Outer Mitochondrial Membrane by Superoxide Induces Rapid and Massive Cytochrome c Release von Madesh, Muniswamy, Hajnóczky, György

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Mitochondrial Ca2+ transport in the endothelium: regulation by ions, redox signalling and mechanical forces von Alevriadou, B. Rita, Shanmughapriya, Santhanam, Patel, Akshar, Stathopulos, Peter B., Madesh, Muniswamy

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A Selective and Cell-Permeable Mitochondrial Calcium Uniporter (MCU) Inhibitor Preserves Mitochondrial Bioenergetics after Hypoxia/Reoxygenation Injury von Woods, Joshua J, Nemani, Neeharika, Shanmughapriya, Santhanam, Kumar, Akshay, Zhang, MengQi, Nathan, Sarah R, Thomas, Manfred, Carvalho, Edmund, Ramachandran, Karthik, Srikantan, Subramanya, Stathopulos, Peter B, Wilson, Justin J, Madesh, Muniswamy

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Transient receptor potential ion channel TRPM2 promotes AML proliferation and survival through modulation of mitochondrial function, ROS, and autophagy von Chen, Shu-jen, Bao, Lei, Keefer, Kerry, Shanmughapriya, Santhanam, Chen, Longgui, Lee, John, Wang, JuFang, Zhang, Xue-Qian, Hirschler-Laszkiewicz, Iwona, Merali, Salim, Merali, Carmen, Imamura, Yuka, Dovat, Sinisa, Madesh, Muniswamy, Cheung, Joseph Y., Wang, Hong-Gang, Miller, Barbara A.

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Mitochondrial Ca²⁺ and membrane potential, an alternative pathway for Interleukin 6 to regulate CD4 cell effector function von Yang, Rui, Lirussi, Dario, Thornton, Tina M, Jelley-Gibbs, Dawn M, Diehl, Sean A, Case, Laure K, Madesh, Muniswamy, Taatjes, Douglas J, Teuscher, Cory, Haynes, Laura, Rincón, Mercedes

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xCT (SLC7A11) expression confers intrinsic resistance to physical plasma treatment in tumor cells von Bekeschus, Sander, Eisenmann, Sebastian, Sagwal, Sanjeev Kumar, Bodnar, Yana, Moritz, Juliane, Poschkamp, Broder, Stoffels, Ingo, Emmert, Steffen, Madesh, Muniswamy, Weltmann, Klaus-Dieter, von Woedtke, Thomas, Gandhirajan, Rajesh Kumar

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Bad Targets the Permeability Transition Pore Independent of Bax or Bak to Switch between Ca2+-Dependent Cell Survival and Death von Roy, Soumya Sinha, Madesh, Muniswamy, Davies, Erika, Antonsson, Bruno, Danial, Nika, Hajnóczky, György

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Transient Receptor Potential Channels Contribute to Pathological Structural and Functional Remodeling After Myocardial Infarction von Makarewich, Catherine A, Zhang, Hongyu, Davis, Jennifer, Correll, Robert N, Trappanese, Danielle M, Hoffman, Nicholas E, Troupes, Constantine D, Berretta, Remus M, Kubo, Hajime, Madesh, Muniswamy, Chen, Xiongwen, Gao, Erhe, Molkentin, Jeffery D, Houser, Steven R

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