Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy von Tajan, Mylène, Hennequart, Marc, Cheung, Eric C., Zani, Fabio, Hock, Andreas K., Legrave, Nathalie, Maddocks, Oliver D. K., Ridgway, Rachel A., Athineos, Dimitris, Suárez-Bonnet, Alejandro, Ludwig, Robert L., Novellasdemunt, Laura, Angelis, Nikolaos, Li, Vivian S. W., Vlachogiannis, Georgios, Valeri, Nicola, Mainolfi, Nello, Suri, Vipin, Friedman, Adam, Manfredi, Mark, Blyth, Karen, Sansom, Owen J., Vousden, Karen H.

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Serine is a natural ligand and allosteric activator of pyruvate kinase M2 von Chaneton, Barbara, Hillmann, Petra, Zheng, Liang, Martin, Agnès C. L., Maddocks, Oliver D. K., Chokkathukalam, Achuthanunni, Coyle, Joseph E., Jankevics, Andris, Holding, Finn P., Vousden, Karen H., Frezza, Christian, O’Reilly, Marc, Gottlieb, Eyal

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Metabolic regulation by p53 von Maddocks, Oliver D. K., Vousden, Karen H.

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Metabolic cross-feeding in imbalanced diets allows gut microbes to improve reproduction and alter host behaviour von Henriques, Sílvia F., Dhakan, Darshan B., Serra, Lúcia, Francisco, Ana Patrícia, Carvalho-Santos, Zita, Baltazar, Célia, Elias, Ana Paula, Anjos, Margarida, Zhang, Tong, Maddocks, Oliver D. K., Ribeiro, Carlos

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Serine and Functional Metabolites in Cancer von Newman, Alice C, Maddocks, Oliver D.K

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Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells von Maddocks, Oliver D. K., Berkers, Celia R., Mason, Susan M., Zheng, Liang, Blyth, Karen, Gottlieb, Eyal, Vousden, Karen H.

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The KRAS-BCAA-BCAT2 axis in PDAC development von Falcone, Mattia, Maddocks, Oliver D. K.

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Attaching and effacing Escherichia coli downregulate DNA mismatch repair protein in vitro and are associated with colorectal adenocarcinomas in humans von Maddocks, Oliver D K, Short, Abigail J, Donnenberg, Michael S, Bader, Scott, Harrison, David J

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Sensitisation of cancer cells to radiotherapy by serine and glycine starvation von Falcone, Mattia, Uribe, Alejandro Huerta, Papalazarou, Vasileios, Newman, Alice C., Athineos, Dimitris, Stevenson, Katrina, Sauvé, Charles-Etienne Gabriel, Gao, Yajing, Kim, Jin K., Del Latto, Michael, Kierstead, Maria, Wu, Chao, Smith, J. Joshua, Romesser, Paul B., Chalmers, Anthony J., Blyth, Karen, Maddocks, Oliver D. K.

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The creatine–phosphagen system is mechanoresponsive in pancreatic adenocarcinoma and fuels invasion and metastasis von Papalazarou, Vassilis, Zhang, Tong, Paul, Nikki R., Juin, Amelie, Cantini, Marco, Maddocks, Oliver D. K., Salmeron-Sanchez, Manuel, Machesky, Laura M.

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Persistent mTORC1 signaling in cell senescence results from defects in amino acid and growth factor sensing von Carroll, Bernadette, Nelson, Glyn, Rabanal-Ruiz, Yoana, Kucheryavenko, Olena, Dunhill-Turner, Natasha A, Chesterman, Charlotte C, Zahari, Qabil, Zhang, Tong, Conduit, Sarah E, Mitchell, Christina A, Maddocks, Oliver D K, Lovat, Penny, von Zglinicki, Thomas, Korolchuk, Viktor I

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mTORC1 activity is supported by spatial association with focal adhesions von Rabanal-Ruiz, Yoana, Byron, Adam, Wirth, Alexander, Madsen, Ralitsa, Sedlackova, Lucia, Hewitt, Graeme, Nelson, Glyn, Stingele, Julian, Wills, Jimi C, Zhang, Tong, Zeug, André, Fässler, Reinhard, Vanhaesebroeck, Bart, Maddocks, Oliver D K, Ponimaskin, Evgeni, Carroll, Bernadette, Korolchuk, Viktor I

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Targeting the autophagy-NAD axis protects against cell death in Niemann-Pick type C1 disease models von Kataura, Tetsushi, Sedlackova, Lucia, Sun, Congxin, Kocak, Gamze, Wilson, Niall, Banks, Peter, Hayat, Faisal, Trushin, Sergey, Trushina, Eugenia, Maddocks, Oliver D. K., Oblong, John E., Miwa, Satomi, Imoto, Masaya, Saiki, Shinji, Erskine, Daniel, Migaud, Marie E., Sarkar, Sovan, Korolchuk, Viktor I.

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One-carbon metabolism in cancer von Newman, Alice C, Maddocks, Oliver D K

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Mechanistic insights into p53‐regulated cytotoxicity of combined entinostat and irinotecan against colorectal cancer cells von Marx, Christian, Sonnemann, Jürgen, Beyer, Mandy, Maddocks, Oliver D. K., Lilla, Sergio, Hauzenberger, Irene, Piée‐Staffa, Andrea, Siniuk, Kanstantsin, Nunna, Suneetha, Marx‐Blümel, Lisa, Westermann, Martin, Wagner, Tobias, Meyer, Felix B., Thierbach, René, Mullins, Christina S., Kdimati, Said, Linnebacher, Michael, Neri, Francesco, Heinzel, Thorsten, Wang, Zhao‐Qi, Krämer, Oliver H.

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Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity von Carroll, Bernadette, Maetzel, Dorothea, Maddocks, Oliver Dk, Otten, Gisela, Ratcliff, Matthew, Smith, Graham R, Dunlop, Elaine A, Passos, João F, Davies, Owen R, Jaenisch, Rudolf, Tee, Andrew R, Sarkar, Sovan, Korolchuk, Viktor I

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Serine Metabolism Supports the Methionine Cycle and DNA/RNA Methylation through De Novo ATP Synthesis in Cancer Cells von Maddocks, Oliver D.K., Labuschagne, Christiaan F., Adams, Peter D., Vousden, Karen H.

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Supply and demand: Cellular nutrient uptake and exchange in cancer von Papalazarou, Vasileios, Maddocks, Oliver D.K.

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Metabolic Regulation by p53 Family Members von Berkers, Celia R., Maddocks, Oliver D.K., Cheung, Eric C., Mor, Inbal, Vousden, Karen H.

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PHD1 regulates p53‐mediated colorectal cancer chemoresistance von Deschoemaeker, Sofie, Di Conza, Giusy, Lilla, Sergio, Martín‐Pérez, Rosa, Mennerich, Daniela, Boon, Lise, Hendrikx, Stefanie, Maddocks, Oliver DK, Marx, Christian, Radhakrishnan, Praveen, Prenen, Hans, Schneider, Martin, Myllyharju, Johanna, Kietzmann, Thomas, Vousden, Karen H, Zanivan, Sara, Mazzone, Massimiliano

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