Paltusotine, a novel oral once-daily nonpeptide SST2 receptor agonist, suppresses GH and IGF-1 in healthy volunteers von Madan, Ajay, Markison, Stacy, Betz, Stephen F., Krasner, Alan, Luo, Rosa, Jochelson, Theresa, Lickliter, Jason, Struthers, R. Scott

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Validation and application of a liquid chromatography–tandem mass spectrometric method for the simultaneous determination of testosterone and dihydrotestosterone in rat prostatic t... von O’Brien, Zhihong, Post, Noah, Brown, Michael, Madan, Ajay, Coon, Timothy, Luo, Rosa, Kohout, Trudy A.

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Characterization of Novel Selective H1-Antihistamines for Clinical Evaluation in the Treatment of Insomnia von Moree, Wilna J, Li, Bin-Feng, Jovic, Florence, Coon, Timothy, Yu, Jinghua, Gross, Raymond S, Tucci, Fabio, Marinkovic, Dragan, Zamani-Kord, Said, Malany, Siobhan, Bradbury, Margaret J, Hernandez, Lisa M, O’Brien, Zhihong, Wen, Jianyun, Wang, Hua, Hoare, Samuel R. J, Petroski, Robert E, Sacaan, Aida, Madan, Ajay, Crowe, Paul D, Beaton, Graham

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A pharmacokinetic evaluation of five H1 antagonists after an oral and intravenous microdose to human subjects von Madan, Ajay, O'Brien, Zhihong, Wen, Jianyun, O'Brien, Chris, Farber, Robert H., Beaton, Graham, Crowe, Paul, Oosterhuis, Berend, Garner, R. Colin, Lappin, Graham, Bozigian, Haig P.

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Inhibition of Coumarin 7-Hydroxylase Activity in Human Liver Microsomes von Draper, Alison J., Madan, Ajay, Parkinson, Andrew

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Pharmacologic Characterization of Valbenazine (NBI-98854) and Its Metabolites von Grigoriadis, Dimitri E, Smith, Evan, Hoare, Sam R J, Madan, Ajay, Bozigian, Haig

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COVID-19: A gender-biased pandemic von Singh, Ridhima, Saluja, Pulin, Madan, Ajay

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Comparative Evaluation of the Effect of Menstruation, Pregnancy and Menopause on Salivary Flow Rate, pH and Gustatory Function von Saluja, Pulin, Shetty, Vishwaprakash, Dave, Aparna, Arora, Manpreet, Hans, Vibha, Madan, Ajay

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Expression and regulation of cytochrome P450 enzymes in primary cultures of human hepatocytes von LeCluyse, Edward L., Madan, Ajay, Hamilton, Geraldine, Carroll, Kathy, DeHaan, Ryan, Parkinson, Andrew

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Selectivity profiling of novel indene H1-antihistamines for the treatment of insomnia von LI, Bin-Feng, MOREE, Wilna J, HOARE, Samuel R. J, PETROSKI, Robert E, MADAN, Ajay, CROWE, Paul D, BEATON, Graham, JINGHUA YU, COON, Timothy, ZAMANI-KORD, Said, MALANY, Siobhan, JALALI, Kayvon, JIANYUN WEN, HUA WANG, CHUN YANG

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Novel benzothiophene H1-antihistamines for the treatment of insomnia von MOREE, Wilna J, JOVIC, Florence, HERNANDEZ, Lisa M, O'BRIEN, Zhihong, JIANYUN WEN, HUA WANG, HOARE, Samuel R. J, PETROSKI, Robert E, SACAAN, Aida, MADAN, Ajay, CROWE, Paul D, BEATON, Graham, COON, Timothy, JINGHUA YU, LI, Bin-Feng, TUCCI, Fabio C, MARINKOVIC, Dragan, GROSS, Raymond S, MALANY, Siobhan, BRADBURY, Margaret J

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Distribution, metabolism, and excretion of the anti-angiogenic compound SU5416 von Ye, Christine, Sweeny, David, Sukbuntherng, Juthamas, Zhang, Qingling, Tan, Weiwei, Wong, Simon, Madan, Ajay, Ogilvie, Brian, Parkinson, Andrew, Antonian, Lida

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Effects of Freezing, Thawing, and Storing Human Liver Microsomes on Cytochrome P450 Activity von Pearce, Robin E., McIntyre, Christin J., Madan, Ajay, Sanzgiri, Uma, Draper, Alison J., Bullock, Peter L., Cook, Dorn C., Burton, L.Alayne, Latham, Jason, Nevins, Cheryl, Parkinson, Andrew

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Pharmacologic Characteristics of Valbenazine (NBI-98854) and its Metabolites (P2.025) von Grigoriadis, Dimitri, Smith, Evan, Madan, Ajay, Wright, Clinton, Bozigian, Haig

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ACROBAT Edge: Safety and Efficacy of Switching Injected SRLs to Oral Paltusotine in Patients With Acromegaly von Gadelha, Monica R, Gordon, Murray B, Doknic, Mirjana, Mezősi, Emese, Tóth, Miklós, Randeva, Harpal, Marmon, Tonya, Jochelson, Theresa, Luo, Rosa, Monahan, Michael, Madan, Ajay, Ferrara-Cook, Christine, Struthers, R Scott, Krasner, Alan

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Design, Synthesis, In Vitro, and In Vivo Characterization of Phenylpiperazines and Pyridinylpiperazines as Potent and Selective Antagonists of the Melanocortin-4 Receptor von Tran, Joe A, Jiang, Wanlong, Tucci, Fabio C, Fleck, Beth A, Wen, Jenny, Sai, Yang, Madan, Ajay, Chen, Ta Kung, Markison, Stacy, Foster, Alan C, Hoare, Sam R, Marks, Daniel, Harman, John, Chen, Caroline W, Arellano, Melissa, Marinkovic, Dragan, Bozigian, Haig, Saunders, John, Chen, Chen

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Influence of pKₐ on the biotransformation of indene H₁-antihistamines by CYP2D6 von Huang, Charles, Moree, Wilna J, Zamani-Kord, Said, Li, Bin-Feng, Tucci, Fabio C, Malany, Siobhan, Wen, Jianyun, Wang, Hua, Hoare, Samuel R.J, Yang, Chun, Madan, Ajay, Crowe, Paul D, Beaton, Graham

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Potent and orally active non-peptide antagonists of the human melanocortin-4 receptor based on a series of trans-2-disubstituted cyclohexylpiperazines von Tucci, Fabio C., White, Nicole S., Markison, Stacy, Joppa, Margaret, Tran, Joe A., Fleck, Beth A., Madan, Ajay, Dyck, Brian P., Parker, Jessica, Pontillo, Joseph, Melissa Arellano, L., Marinkovic, Dragan, Jiang, Wanlong, Chen, Caroline W., Gogas, Kathleen R., Goodfellow, Val S., Saunders, John, Foster, Alan C., Chen, Chen

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Discovery of Paltusotine (CRN00808), a Potent, Selective, and Orally Bioavailable Non-peptide SST2 Agonist von Zhao, Jian, Wang, Shimiao, Markison, Stacy, Kim, Sun Hee, Han, Sangdon, Chen, Mi, Kusnetzow, Ana Karin, Rico-Bautista, Elizabeth, Johns, Michael, Luo, Rosa, Struthers, R. Scott, Madan, Ajay, Zhu, Yunfei, Betz, Stephen F.

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COVID-19: A gender-biased pandemic von Singh, Ridhima, Saluja, Pulin, Madan, Ajay

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