Metformin increases degradation of phospholamban via autophagy in cardiomyocytes von Teng, Allen C. T., Miyake, Tetsuaki, Yokoe, Shunichi, Zhang, Liyong, Rezende, Luís Mário, Sharma, Parveen, MacLennan, David H., Liu, Peter P., Gramolini, Anthony O.

Volltext

Dilated Cardiomyopathy and Heart Failure Caused by a Mutation in Phospholamban von Schmitt, Joachim P., Kamisago, Mitsuhiro, Asahi, Michio, Li, Guo Hua, Ahmad, Ferhaan, Mende, Ulrike, Kranias, Evangelia G., MacLennan, David H., Seidman, J. G., Seidman, Christine E.

Volltext

Store overload‐induced Ca2+ release as a triggering mechanism for CPVT and MH episodes caused by mutations in RYR and CASQ genes von MacLennan, David H., Chen, S. R. Wayne

Volltext

A Mutation in the Human Phospholamban Gene, Deleting Arginine 14, Results in Lethal, Hereditary Cardiomyopathy von Haghighi, Kobra, Kolokathis, Fotis, Gramolini, Anthony O., Waggoner, Jason R., Pater, Luke, Lynch, Roy A., Fan, Guo-Chang, Tsiapras, Dimitris, Parekh, Rohan R., Dorn, Gerald W., MacLennan, David H., Kremastinos, Dimitrios Th, Kranias, Evangelia G.

Volltext

Crystal structure of type I ryanodine receptor amino-terminal β-trefoil domain reveals a disease-associated mutation “hot spot” loop von Amador, Fernando J, Liu, Shuang, Ishiyama, Noboru, Plevin, Michael J, Wilson, Aaron, MacLennan, David H, Ikura, Mitsuhiko

Volltext

Structural determination of the phosphorylation domain of the ryanodine receptor von Sharma, Parveen, Ishiyama, Noboru, Nair, Usha, Li, Wenping, Dong, Aiping, Miyake, Tetsuaki, Wilson, Aaron, Ryan, Tim, MacLennan, David H., Kislinger, Thomas, Ikura, Mitsuhiko, Dhe‐Paganon, Sirano, Gramolini, Anthony O.

Volltext

Human phospholamban null results in lethal dilated cardiomyopathy revealing a critical difference between mouse and human von Haghighi, Kobra, Kolokathis, Fotis, Pater, Luke, Lynch, Roy A, Asahi, Michio, Gramolini, Anthony O, Fan, Guo-Chang, Tsiapras, Dimitris, Hahn, Harvey S, Adamopoulos, Stamatis, Liggett, Stephen B, Dorn, 2nd, Gerald W, MacLennan, David H, Kremastinos, Dimitrios T, Kranias, Evangelia G

Volltext

Enhanced Ca2+ transport and muscle relaxation in skeletal muscle from sarcolipin-null mice von Tupling, A Russell, Bombardier, Eric, Gupta, Subash C, Hussain, Dawar, Vigna, Chris, Bloemberg, Darin, Quadrilatero, Joe, Trivieri, Maria G, Babu, Gopal J, Backx, Peter H, Periasamy, Muthu, MacLennan, David H, Gramolini, Anthony O

Volltext

Mechanistic models for muscle diseases and disorders originating in the sarcoplasmic reticulum von MacLennan, David H., Zvaritch, Elena

Volltext

Constitutively active calcineurin induces cardiac endoplasmic reticulum stress and protects against apoptosis that is mediated by α-crystallin-B von Bousette, Nicolas, Chugh, Shaan, Fong, Vincent, Isserlin, Ruth, Kim, Kyoung-Han, Volchuk, Allen, Backx, Peter H, Liu, Peter, Kislinger, Thomas, MacLennan, David H, Emili, Andrew, Gramolini, Anthony O

Volltext

Proteome Dynamics during C2C12 Myoblast Differentiation von Kislinger, Thomas, Gramolini, Anthony O, Pan, Yan, Rahman, Khaled, MacLennan, David H, Emili, Andrew

Volltext

Modeling of the Inhibitory Interaction of Phospholamban with the Ca2+ATPase von Toyoshima, Chikashi, Asahi, Michio, Sugita, Yuji, Khanna, Reena, Tsuda, Takeo, MacLennan, David H.

Volltext

The Regulation of SERCA-Type Pumps by Phospholamban and Sarcolipin von MacLENNAN, DAVID H., ASAHI, MICHIO, TUPLING, A. RUSSELL

Volltext

Phospholamban: a crucial regulator of cardiac contractility von MacLennan, David H, Kranias, Evangelia G

Volltext

Correlations between genotype and pharmacological, histological, functional, and clinical phenotypes in malignant hyperthermia susceptibility von Monnier, Nicole, Kozak-Ribbens, Geneviève, Krivosic-Horber, Renée, Nivoche, Yves, Qi, Dong, Kraev, Natasha, Loke, Julian, Sharma, Parveen, Tegazzin, Vincenzo, Figarella-Branger, Dominique, Roméro, Norma, Mezin, Paulette, Bendahan, David, Payen, Jean-François, Depret, Thierry, Maclennan, David H., Lunardi, Joël

Volltext

Cardiac-Specific Elevations in Thyroid Hormone Enhance Contractility and Prevent Pressure Overload-Induced Cardiac Dysfunction von Trivieri, Maria Giovanna, Oudit, Gavin Y., Sah, Rajan, Kerfant, Benoit-Gilles, Sun, Hui, Gramolini, Anthony O., Pan, Yan, Wickenden, Alan D., Croteau, Walburga, de Escobar, Gabriella Morreale, Pekhletski, Roman, Germain, Donald St, MacLennan, David H., Backx, Peter H.

Volltext

Comparative Proteomics Profiling of a Phospholamban Mutant Mouse Model of Dilated Cardiomyopathy Reveals Progressive Intracellular Stress Responses von Gramolini, Anthony O., Kislinger, Thomas, Alikhani-Koopaei, Rasoul, Fong, Vincent, Thompson, Natalie J., Isserlin, Ruth, Sharma, Parveen, Oudit, Gavin Y., Trivieri, Maria G., Fagan, Ailís, Kannan, Anitha, Higgins, Desmond G., Huedig, Hendrik, Hess, George, Arab, Sara, Seidman, Jonathan G., Seidman, Christine E., Frey, Brendan, Perry, Marc, Backx, Peter H., Liu, Peter P., MacLennan, David H., Emili, Andrew

Volltext

Type 1 ryanodine receptor knock-in mutation causing central core disease of skeletal muscle also displays a neuronal phenotype von De Crescenzo, Valerie, Fogarty, Kevin E, Lefkowitz, Jason J, Bellve, Karl D, Zvaritch, Elena, MacLennan, David H, Walsh, John V. Jr

Volltext

Tbx5-dependent pathway regulating diastolic function in congenital heart disease von Zhu, Yonghong, Gramolini, Anthony O, Walsh, Mark A, Zhou, Yu-Qing, Slorach, Cameron, Friedberg, Mark K, Takeuchi, Jun K, Sun, Hui, Henkelman, R. Mark, Backx, Peter H, Redington, Andrew N, MacLennan, David H, Bruneau, Benoit G

Volltext

Cardiac-Specific Overexpression of Sarcolipin in Phospholamban Null Mice Impairs Myocyte Function That Is Restored by Phosphorylation von Gramolini, Anthony O., Trivieri, Maria G., Oudit, Gavin Y., Kislinger, Thomas, Li, Wenping, Patel, Mikin M., Emili, Andrew, Kranias, Evangelia G., Backx, Peter H., MacLennan, David H.

Volltext