CRISPR-Cas9 DNA Base-Editing and Prime-Editing von Kantor, Ariel, McClements, Michelle E., MacLaren, Robert E.

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Gene therapy in the early stages of retinal degeneration von MacLaren, Robert E

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A 2020 vision of ocular gene therapy von MacLaren, Robert E.

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Retinal gene therapy in patients with choroideremia: initial findings from a phase 1/2 clinical trial von MacLaren, Robert E, Prof, Groppe, Markus, PhD, Barnard, Alun R, PhD, Cottriall, Charles L, PhD, Tolmachova, Tanya, PhD, Seymour, Len, Prof, Clark, K Reed, PhD, During, Matthew J, Prof, Cremers, Frans P M, Prof, Black, Graeme C M, Prof, Lotery, Andrew J, Prof, Downes, Susan M, FRCOphth, Webster, Andrew R, Prof, Seabra, Miguel C, Prof

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Initial results from a first-in-human gene therapy trial on X-linked retinitis pigmentosa caused by mutations in RPGR von Cehajic-Kapetanovic, Jasmina, Xue, Kanmin, Martinez-Fernandez de la Camara, Cristina, Nanda, Anika, Davies, Alexandra, Wood, Laura J., Salvetti, Anna Paola, Fischer, M. Dominik, Aylward, James W., Barnard, Alun R., Jolly, Jasleen K., Luo, Edmond, Lujan, Brandon J., Ong, Tuyen, Girach, Aniz, Black, Graeme C. M., Gregori, Ninel Z., Davis, Janet L., Rosa, Potyra R., Lotery, Andrew J., Lam, Byron L., Stanga, Paulo E., MacLaren, Robert E.

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Clinical applications of retinal gene therapy von Lipinski, Daniel M., Thake, Miriam, MacLaren, Robert E.

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Choroideremia Gene Therapy Phase 2 Clinical Trial: 24-Month Results von Lam, Byron L., Davis, Janet L., Gregori, Ninel Z., MacLaren, Robert E., Girach, Aniz, Verriotto, Jennifer D., Rodriguez, Belen, Rosa, Potyra R., Zhang, Xiaojun, Feuer, William J.

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Two-Year Results After AAV2-Mediated Gene Therapy for Choroideremia: The Alberta Experience von Dimopoulos, Ioannis S., Hoang, Stephanie C., Radziwon, Alina, Binczyk, Natalia M., Seabra, Miguel C., MacLaren, Robert E., Somani, Rizwan, Tennant, Matthew T.S., MacDonald, Ian M.

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Transplanted photoreceptor precursors transfer proteins to host photoreceptors by a mechanism of cytoplasmic fusion von Singh, Mandeep S., Balmer, Jasmin, Barnard, Alun R., Aslam, Sher A., Moralli, Daniela, Green, Catherine M., Barnea-Cramer, Alona, Duncan, Isabel, MacLaren, Robert E.

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Rescue of the Stargardt phenotype in Abca4 knockout mice through inhibition of vitamin A dimerization von Charbel Issa, Peter, Alun R. Barnard, Philipp Herrmann, Ilyas Washington, Robert E. MacLaren

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Beneficial effects on vision in patients undergoing retinal gene therapy for choroideremia von Xue, Kanmin, Jolly, Jasleen K, Barnard, Alun R., Rudenko, Anna, Salvetti, Anna P., Patrício, Maria I., Edwards, Thomas L., Groppe, Markus, Orlans, Harry O., Tolmachova, Tanya, Black, Graeme C., Webster, Andrew R., Lotery, Andrew J., Holder, Graham E., Downes, Susan M., Seabra, Miguel C., MacLaren, Robert E.

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Assessment of the Electronic Retinal Implant Alpha AMS in Restoring Vision to Blind Patients with End-Stage Retinitis Pigmentosa von Edwards, Thomas L., Cottriall, Charles L., Xue, Kanmin, Simunovic, Matthew P., Ramsden, James D., Zrenner, Eberhart, MacLaren, Robert E.

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Optogenetic Gene Therapy for the Degenerate Retina: Recent Advances von McClements, Michelle E., Staurenghi, Federica, MacLaren, Robert E., Cehajic-Kapetanovic, Jasmina

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Immunomodulatory Effects of Hydroxychloroquine and Chloroquine in Viral Infections and Their Potential Application in Retinal Gene Therapy von Chandler, Laurel C., Yusuf, Imran H., McClements, Michelle E., Barnard, Alun R., MacLaren, Robert E., Xue, Kanmin

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Gene Therapy and Stem Cell Transplantation in Retinal Disease: The New Frontier von MacLaren, Robert E., DPhil, FRCS, Bennett, Jean, MD, PhD, Schwartz, Steven D., MD

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Will Nanotechnology Bring New Hope for Gene Delivery? von Wong, Joanna K.L, Mohseni, Rashin, Hamidieh, Amir Ali, MacLaren, Robert E, Habib, Nagy, Seifalian, Alexander M

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Subretinal Visual Implant Alpha IMS – Clinical trial interim report von Stingl, Katarina, Bartz-Schmidt, Karl Ulrich, Besch, Dorothea, Chee, Caroline K., Cottriall, Charles L., Gekeler, Florian, Groppe, Markus, Jackson, Timothy L., MacLaren, Robert E., Koitschev, Assen, Kusnyerik, Akos, Neffendorf, James, Nemeth, Janos, Naeem, Mohamed Adheem Naser, Peters, Tobias, Ramsden, James D., Sachs, Helmut, Simpson, Andrew, Singh, Mandeep S., Wilhelm, Barbara, Wong, David, Zrenner, Eberhart

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Retinal stem cell transplantation: Balancing safety and potential von Singh, Mandeep S., Park, Susanna S., Albini, Thomas A., Canto-Soler, M. Valeria, Klassen, Henry, MacLaren, Robert E., Takahashi, Masayo, Nagiel, Aaron, Schwartz, Steven D., Bharti, Kapil

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Reversal of end-stage retinal degeneration and restoration of visual function by photoreceptor transplantation von Singh, Mandeep S., Issa, Peter Charbel, Butler, Rachel, Martin, Chris, Lipinski, Daniel M., Sekaran, Sumathi, Barnard, Alun R., MacLaren, Robert E.

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Analysis of Pathogenic Variants Correctable With CRISPR Base Editing Among Patients With Recessive Inherited Retinal Degeneration von Fry, Lewis E, McClements, Michelle E, MacLaren, Robert E

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