New prospects for targeting telomerase beyond the telomere von Arndt, Greg M., MacKenzie, Karen L.

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SIRT1 promotes N-Myc oncogenesis through a positive feedback loop involving the effects of MKP3 and ERK on N-Myc protein stability von Marshall, Glenn M, Liu, Pei Y, Gherardi, Samuele, Scarlett, Christopher J, Bedalov, Antonio, Xu, Ning, Iraci, Nuncio, Valli, Emanuele, Ling, Dora, Thomas, Wayne, van Bekkum, Margo, Sekyere, Eric, Jankowski, Kacper, Trahair, Toby, Mackenzie, Karen L, Haber, Michelle, Norris, Murray D, Biankin, Andrew V, Perini, Giovanni, Liu, Tao

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Differentially expressed genes from RNA-Seq and functional enrichment results are affected by the choice of single-end versus paired-end reads and stranded versus non-stranded prot... von Corley, Susan M, MacKenzie, Karen L, Beverdam, Annemiek, Roddam, Louise F, Wilkins, Marc R

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CD30 and ALK combination therapy has high therapeutic potency in RANBP2-ALK-rearranged epithelioid inflammatory myofibroblastic sarcoma von Fordham, Ashleigh M., Xie, Jinhan, Gifford, Andrew J., Wadham, Carol, Morgan, Lisa T., Mould, Emily V. A., Fadia, Mitali, Zhai, Lei, Massudi, Hassina, Ali, Zara S., Marshall, Glenn M., Lukeis, Robyn E., Fletcher, Jamie I., MacKenzie, Karen L., Trahair, Toby N.

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DKC1 is a transcriptional target of GATA1 and drives upregulation of telomerase activity in normal human erythroblasts von Richards, Laura A., Kumari, Ashu, Knezevic, Kathy, Al Thoms, Julie, von Jonquieres, Georg, Napier, Christine E., Ali, Zara, O'Brien, Rosemary, Marks-Bluth, Jonathon, Maritz, Michelle F., Pickett, Hilda A., Morris, Jonathan, Pimanda, John E., MacKenzie, Karen L.

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Therapeutic targeting of replicative immortality von Yaswen, Paul, MacKenzie, Karen L, Keith, W. Nicol, Hentosh, Patricia, Rodier, Francis, Zhu, Jiyue, Firestone, Gary L, Matheu, Ander, Carnero, Amancio, Bilsland, Alan, Sundin, Tabetha, Honoki, Kanya, Fujii, Hiromasa, Georgakilas, Alexandros G, Amedei, Amedeo, Amin, Amr, Helferich, Bill, Boosani, Chandra S, Guha, Gunjan, Ciriolo, Maria Rosa, Chen, Sophie, Mohammed, Sulma I, Azmi, Asfar S, Bhakta, Dipita, Halicka, Dorota, Niccolai, Elena, Aquilano, Katia, Ashraf, S. Salman, Nowsheen, Somaira, Yang, Xujuan

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MYC-Driven Neuroblastomas Are Addicted to a Telomerase-Independent Function of Dyskerin von O'Brien, Rosemary, Tran, Sieu L, Maritz, Michelle F, Liu, Bing, Kong, Cheng Fei, Purgato, Stefania, Yang, Chen, Murray, Jayne, Russell, Amanda J, Flemming, Claudia L, von Jonquieres, Georg, Pickett, Hilda A, London, Wendy B, Haber, Michelle, Gunaratne, Preethi H, Norris, Murray D, Perini, Giovanni, Fletcher, Jamie I, MacKenzie, Karen L

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Retrospective analysis of clinical characteristics and outcomes of patients with carcinoma of unknown primary from three tertiary centers in Australia von Boys, Emma L., Gao, Bo, Grimison, Peter, Sutherland, Sarah, MacKenzie, Karen L., Reddel, Roger R., Liu, Jia

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Effective Management of Advanced Angiosarcoma by the Synergistic Combination of Propranolol and Vinblastine-based Metronomic Chemotherapy: A Bench to Bedside Study von Pasquier, Eddy, André, Nicolas, Street, Janine, Chougule, Anuradha, Rekhi, Bharat, Ghosh, Jaya, Philip, Deepa S.J., Meurer, Marie, MacKenzie, Karen L., Kavallaris, Maria, Banavali, Shripad D.

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Concentration- and schedule-dependent effects of chemotherapy on the angiogenic potential and drug sensitivity of vascular endothelial cells von Pasquier, Eddy, Tuset, Maria-Pia, Street, Janine, Sinnappan, Snega, MacKenzie, Karen L., Braguer, Diane, Andre, Nicolas, Kavallaris, Maria

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Characterization of childhood acute lymphoblastic leukemia xenograft models for the preclinical evaluation of new therapies von Liem, Natalia L.M., Papa, Rachael A., Milross, Christopher G., Schmid, Michael A., Tajbakhsh, Mayamin, Choi, Seoyeon, Ramirez, Carole D., Rice, Alison M., Haber, Michelle, Norris, Murray D., MacKenzie, Karen L., Lock, Richard B.

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Pan-cancer proteomic map of 949 human cell lines von Gonçalves, Emanuel, Poulos, Rebecca C., Cai, Zhaoxiang, Barthorpe, Syd, Manda, Srikanth S., Lucas, Natasha, Beck, Alexandra, Bucio-Noble, Daniel, Dausmann, Michael, Hall, Caitlin, Hecker, Michael, Koh, Jennifer, Lightfoot, Howard, Mahboob, Sadia, Mali, Iman, Morris, James, Richardson, Laura, Seneviratne, Akila J., Shepherd, Rebecca, Sykes, Erin, Thomas, Frances, Valentini, Sara, Williams, Steven G., Wu, Yangxiu, Xavier, Dylan, MacKenzie, Karen L., Hains, Peter G., Tully, Brett, Robinson, Phillip J., Zhong, Qing, Garnett, Mathew J., Reddel, Roger R.

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Modeling human endothelial cell transformation in vascular neoplasias von Wen, Victoria W, MacKenzie, Karen L

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Dexamethasone resistance in B-cell precursor childhood acute lymphoblastic leukemia occurs downstream of ligand-induced nuclear translocation of the glucocorticoid receptor von Bachmann, Petra S., Gorman, Rosemary, MacKenzie, Karen L., Lutze-Mann, Louise, Lock, Richard B.

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The AML1-ETO fusion protein promotes the expansion of human hematopoietic stem cells von Mulloy, James C., Cammenga, Jörg, MacKenzie, Karen L., Berguido, Francisco J., Moore, Malcolm A.S., Nimer, Stephen D.

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FLT-3: a new focus in the understanding of acute leukemia von Markovic, Ana, MacKenzie, Karen L., Lock, Richard B.

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End Products of Telomere Research von Reddel, Roger R., MacKenzie, Karen L., Bryan, Tracy M.

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WDR5 Supports an N-Myc Transcriptional Complex That Drives a Protumorigenic Gene Expression Signature in Neuroblastoma von Sun, Yuting, Bell, Jessica L, Carter, Daniel, Gherardi, Samuele, Poulos, Rebecca C, Milazzo, Giorgio, Wong, Jason W H, Al-Awar, Rima, Tee, Andrew E, Liu, Pei Y, Liu, Bing, Atmadibrata, Bernard, Wong, Matthew, Trahair, Toby, Zhao, Quan, Shohet, Jason M, Haupt, Ygal, Schulte, Johannes H, Brown, Peter J, Arrowsmith, Cheryl H, Vedadi, Masoud, MacKenzie, Karen L, Hüttelmaier, Stefan, Perini, Giovanni, Marshall, Glenn M, Braithwaite, Antony, Liu, Tao

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Integrative Genomics Identifies the Molecular Basis of Resistance to Azacitidine Therapy in Myelodysplastic Syndromes von Unnikrishnan, Ashwin, Papaemmanuil, Elli, Beck, Dominik, Deshpande, Nandan P., Verma, Arjun, Kumari, Ashu, Woll, Petter S., Richards, Laura A., Knezevic, Kathy, Chandrakanthan, Vashe, Thoms, Julie A.I., Tursky, Melinda L., Huang, Yizhou, Ali, Zara, Olivier, Jake, Galbraith, Sally, Kulasekararaj, Austin G., Tobiasson, Magnus, Karimi, Mohsen, Pellagatti, Andrea, Wilson, Susan R., Lindeman, Robert, Young, Boris, Ramakrishna, Raj, Arthur, Christopher, Stark, Richard, Crispin, Philip, Curnow, Jennifer, Warburton, Pauline, Roncolato, Fernando, Boultwood, Jacqueline, Lynch, Kevin, Jacobsen, Sten Eirik W., Mufti, Ghulam J., Hellstrom-Lindberg, Eva, Wilkins, Marc R., MacKenzie, Karen L., Wong, Jason W.H., Campbell, Peter J., Pimanda, John E.

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Targeted Therapy of TERT -Rearranged Neuroblastoma with BET Bromodomain Inhibitor and Proteasome Inhibitor Combination Therapy von Chen, Jingwei, Nelson, Christopher, Wong, Matthew, Tee, Andrew E, Liu, Pei Y, La, Ting, Fletcher, Jamie I, Kamili, Alvin, Mayoh, Chelsea, Bartenhagen, Christoph, Trahair, Toby N, Xu, Ning, Jayatilleke, Nisitha, Wong, Marie, Peng, Hui, Atmadibrata, Bernard, Cheung, Belamy B, Lan, Qing, Bryan, Tracy M, Mestdagh, Pieter, Vandesompele, Jo, Combaret, Valerie, Boeva, Valentina, Wang, Jenny Y, Janoueix-Lerosey, Isabelle, Cowley, Mark J, MacKenzie, Karen L, Dolnikov, Alla, Li, Jinyan, Polly, Patsie, Marshall, Glenn M, Reddel, Roger R, Norris, Murray D, Haber, Michelle, Fischer, Matthias, Zhang, Xu D, Pickett, Hilda A, Liu, Tao

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