OC.02.2 HUMAN NEUTROPHIL ELASTASE CONTRIBUTES TO LOSS OF FUNCTION OF INFLIXIMAB IN ULCERATIVE COLITIS von Giuffrida, P, Kok, K, Curciarello, R, Vanoli, A, Mazza, G, Biancheri, P, Pasini, A, Pinzani, M, Corazza, G.R, Macdonald, T.T, Di Sabatino, A

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OC.16.1 INTERLEUKIN-17A HOMODIMER REDUCES PRO-INFLAMMATORY CYTOKINE PRODUCTION BY INFLAMMATORY BOWEL DISEASE MUCOSA CULTURED EX VIVO von Biancheri, P, Di Sabatino, A, Curciarello, R, Giuffrida, P, Ammoscato, F, Corazza, G.R, Macdonald, T.T

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OC.16.3 THE ROLE OF HUMAN NEUTROPHIL ELASTASE AND ITS INHIBITOR ELAFIN IN ULCERATIVE COLITIS von Biancheri, P, Kok, K, Di Sabatino, A, Giuffrida, P, Curciarello, R, Corazza, G.R, Macdonald, T.T

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P.11.1 THYMIC STROMAL LYMPHOPOIETIN IS PRIMARILY REDUCED IN REFRACTORY COELIAC DISEASE DUODENAL MUCOSA von Biancheri, P, Di Sabatino, A, Giuffrida, P, Papadia, C, Fornasa, G, Pasini, A, Macdonald, T.T, Rescigno, M, Corazza, G.R

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P.06.8 T HELPER 2 CELLS ARE NOT INCREASED, WHEREAS NATURAL KILLER T CELLS ARE REDUCED IN THE INFLAMED MUCOSA OF ULCERATIVE COLITIS PATIENTS von Biancheri, P, Facciotti, F, Di Sabatino, A, Caprioli, F, Ammoscato, F, Giuffrida, P, Geginat, J, Corazza, G.R, Macdonald, T.T

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OC.07.1 MICRO-RNA EXPRESSION PROFILING IDENTIFIES MIR-29B AS A RELEVANT PRO-FIBROGENIC FACTOR IN CROHN'S DISEASE INTESTINAL STRICTURES von Biancheri, P, Di Sabatino, A, Nijhuis, A, Lai, C, Ghosh, A, Macdonald, T.T, Lindsay, J, Silver, A, Corazza, G.R

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P.03.15 ACTIVATION OF TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 1 INCREASES THE PRODUCTION OF PRO-INFLAMMATORY CYTOKINES IN INFLAMMATORY BOWEL DISEASE MUCOSA von Biancheri, P, Di Sabatino, A, Ammoscato, F, Curciarello, R, Kruidenier, L, Macdonald, T.T, Corazza, G.R

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OC.07.2 SELECTIVE INHIBITION OF RIP2 KINASE ACTIVITY REDUCES PRO-INFLAMMATORY CYTOKINE PRODUCTION IN INFLAMMATORY BOWEL DISEASE MUCOSA von Biancheri, P, Di Sabatino, A, Gough, P, Votta, B, Foley, K, Vossenkaemper, A, Bertin, J, Corazza, G.R, Macdonald, T.T

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P.06.6 PLASMA CELLS IN THE MUCOSA OF PATIENTS WITH INFLAMMATORY BOWEL DISEASE PRODUCE GRANZYME B AND POSSESS CYTOTOXIC ACTIVITIES von Cupi, M.L, Sarra, M, Marafini, I, Monteleone, I, Franzè, E, Sica, G, Sileri, P, Rosado, M.M, Carsetti, R, Macdonald, T.T, Pallone, F, Monteleone, G

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OC.05.2 TH17-RELATED CYTOKINES AND EXCESSIVE ACTIVATION OF STAT3 SUSTAIN COLORECTAL CANCER CELL GROWTH von De Simone, V, Franzè, E, Ronchetti, G, Colantoni, A, Ortenzi, A, Fantini, M.C, Sica, G.S, Sileri, P, Macdonald, T.T, Pallone, F, Monteleone, G, Stolfi, C

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PC.01.2 SMAD7 SUSTAINS COLON CANCER CELL GROWTH BY MODULATING PP1 AND EIF2-ALPHA TO REGULATE CDC25A von Stolfi, C, De Simone, V, Colantoni, A, Franzè, E, Ribichini, E, Fantini, M.C, Caruso, R, Monteleone, I, Sica, G.S, Sileri, P, Macdonald, T.T, Pallone, F, Monteleone, G

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P.12.22 MARKED ACTIVATION OF MUCOSAL PRO-INFLAMMATORY IMMUNE RESPONSE IN DIVERTICULITIS BUT NOT IN DIVERTICULOSIS von Biancheri, P, Di Sabatino, A, Kok, K, Giuffrida, P, Guerci, M, Salvatore, C, Massari, A, Pasini, A, Ubezio, C, Macdonald, T.T, Corazza, G.R

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P.1.61: INVOLVEMENT OF MACROPHAGES IN INTESTINAL STRICTURES IN CROHN'S DISEASE von Biancheri, P, Ghanbari, A, Snoek, S.A, Di Sabatino, A, Macdonald, T.T, Corazza, G.R

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P.05.15 IS ULCERATIVE COLITIS AN ATYPICAL T HELPER 2-MEDIATED DISEASE CHARACTERISED BY EXCESSIVE PRODUCTION OF INTERLEUKIN-13? von Biancheri, P, Ammoscato, F, Di Sabatino, A, Joe-Njoku, I, Rovedatti, L, Pasini, A, Ubezio, C, Guerci, M, Giuffrida, P, Quadrelli, A, Macdonald, T.T, Corazza, G.R

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OC.05.7: PROTECTIVE EFFECTS OF TIMP-3 ON GUT INFLAMMATION von Monteleone, I, Sarra, M, Casagrande, V, Zorzi, F, Cavalera, M, Rizzo, A, Macdonald, T.T, Pallone, F, Federici, M, Monteleone, G

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OC.06.3: EVIDENCE FOR AN ANTI-FIBROGENIC ROLE OF ANANDAMIDE IN CROHN'S DISEASE von Rovedatti, L, Di Sabatino, A, Battista, N, Biancheri, P, Guerci, M, Pender, S, Maccarrone, M, Macdonald, T.T, Corazza, G.R

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OC.06.7: EFFECT OF MATRIX METALLOPROTEINASE (MMP)-3, -8, -10 AND -12 ON THE STRUCTURE AND FUNCTION OF ANTI-TUMOR NECROSIS FACTOR-ALPHA AGENTS IN INFLAMMATORY BOWEL DISEASE von Biancheri, P, Di Sabatino, A, Snoek, S.A, Joe-njoku, I, Rovedatti, L, Ahmad, N, Corazza, G.R, Macdonald, T.T

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FIBROBLAST ACTIVATION PROTEIN EXPRESSION IN CROHN'S DISEASE STRICTURES von Rovedatti, L, Di Sabatino, A, Biancheri, P, Cazzola, P, MacDonald, T.T, Corazza, G.R

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INTERLEUKIN (IL)-25 INHIBITS IL-12 PRODUCTION AND TH1 CELL-DRIVEN INFLAMMATION IN THE GUT von Caruso, R, Sarra, M, Stolfi, C, Rizzo, A, Fantini, M.C, Pallone, F, MacDonald, T.T, Monteleone, G

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DIFFERENTIAL REGULATION OF INTERLEUKIN-17 AND INTERFERON-GAMMA PRODUCTION IN INFLAMMATORY BOWEL DISEASE von Rovedatti, L, Di Sabatino, A, Kudo, T, Biancheri, P, Sarra, M, Monteleone, G, Corazza, G.R, MacDonald, T.T

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