Practice of tracheostomy in patients with acute respiratory failure related to COVID–19 – Insights from the PRoVENT–COVID study von Tsonas, A.M., Botta, M., Horn, J., Brenner, M.J., Teng, M.S., McGrath, B.A., Schultz, M.J., Paulus, F., Serpa Neto, A.

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Epidemiology, ventilation management and outcome in patients receiving intensive care after non–thoracic surgery – Insights from the LAS VEGAS study von Simonis, F.D., Einav, S., Serpa Neto, A., Hemmes, S.N., Pelosi, P., Gama de Abreu, M., Schultz, M.J.

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Clinical Utility of the 12-Gene Ductal Carcinoma In Situ (DCIS) Score Assay: Impact on Treatment (tx) Recommendations von Leonard, C.E, Lei, R.Y, Alvarado, M.D, Guenther, J, Hagans, J.E, Manders, J.B, Schultz, M.J, Sing, A.P, Broder, M.S, Chang, E, Cherepanov, D, Eagan, M, Hsiao, W.C, Carter, D.L

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Disturbed alveolar fibrin turnover during pneumonia is restricted to the site of infection von Choi, G, Schultz, M.J, van Till, J.W.O, Bresser, P, van der Zee, J.S, Boermeester, M.A, Levi, M, van der Poll, T

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Identification and validation of distinct biological phenotypes in patients with acute respiratory distress syndrome by cluster analysis von Bos, L D, Schouten, L R, van Vught, L A, Wiewel, M A, Ong, D S Y, Cremer, O, Artigas, A, Martin-Loeches, I, Hoogendijk, A J, van der Poll, T, Horn, J, Juffermans, N, Calfee, C S, Schultz, M J

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A systematic review and consensus definitions for standardised end-points in perioperative medicine: pulmonary complications von Abbott, T.E.F., Fowler, A.J., Pelosi, P., Gama de Abreu, M., Møller, A.M., Canet, J., Creagh-Brown, B., Mythen, M., Gin, T., Lalu, M.M., Futier, E., Grocott, M.P., Schultz, M.J., Pearse, R.M., Myles, P., Gan, T.J., Kurz, A., Peyton, P., Sessler, D., Tramèr, M., Cyna, A., De Oliveira, G.S., Wu, C., Jensen, M., Kehlet, H., Botti, M., Boney, O., Haller, G., Grocott, M., Cook, T., Fleisher, L., Neuman, M., Story, D., Gruen, R., Bampoe, S., Evered, Lis, Scott, D., Silbert, B., van Dijk, D., Kalkman, C., Chan, M., Grocott, H., Eckenhoff, R., Rasmussen, L., Eriksson, L., Beattie, S., Wijeysundera, D., Landoni, G., Leslie, K., Biccard, B., Howell, S., Nagele, P., Richards, T., Lamy, A., Gabreu, M., Klein, A., Corcoran, T., Jamie Cooper, D., Dieleman, S., Diouf, E., McIlroy, D., Bellomo, R., Shaw, A., Prowle, J., Karkouti, K., Billings, J., Mazer, D., Jayarajah, M., Murphy, M., Bartoszko, J., Sneyd, R., Morris, S., George, R., Moonesinghe, R., Shulman, M., Lane-Fall, M., Nilsson, U., Stevenson, N., van Klei, W., Cabrini, L., Miller, T., Pace, N., Jackson, S., Buggy, D., Short, T., Riedel, B., Gottumukkala, V., Alkhaffaf, B., Johnson, M.

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Coagulopathy and its management in patients with severe burns von Glas, G. J., Levi, M., Schultz, M. J.

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Infectious pleural effusions can be identified by sTREM-1 levels von Determann, R.M, Achouiti, A.A, El Solh, A.A, Bresser, P, Vijfhuizen, J, Spronk, P.E, Schultz, M.J

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Intraoperative ventilation settings and their associations with postoperative pulmonary complications in obese patients von Ball, L., Hemmes, S.N.T., Serpa Neto, A., Bluth, T., Canet, J., Hiesmayr, M., Hollmann, M.W., Mills, G.H., Vidal Melo, M.F., Putensen, C., Schmid, W., Severgnini, P., Wrigge, H., Gama de Abreu, M., Schultz, M.J., Pelosi, P.

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Longitudinal respiratory subphenotypes in patients with COVID-19-related acute respiratory distress syndrome: results from three observational cohorts von Sjoding, Michael, Sinha, Pratik, Bhavani, Sivasubramanium V, Lyons, Patrick G, Bewley, Alice F, Botta, Michela, Tsonas, Anissa M, Serpa Neto, Ary, Schultz, Marcus J, Dickson, Robert P, Paulus, Frederique, van Akkeren, J.P., Algera, A.G., Algoe, C.K., Artigas, A., Baur, O.L., van de Berg, P., van den Berg, A.E., Bergmans, D.C.J.J., van den Bersselaar, D.I., Bindels, A.J.G.H., de Boer, M.M., den Boer, S., Boers, L.S., Bogerd, M., Bos, L.D.J., Botta, M., Breel, J.S., de Bruin, H., de Bruin, S., Buiteman-Kruizinga, L.A., Cremer, O., Determann, R.M., Dieperink, W., Dongelmans, D.A., Franke, H.S., Galek-Aldridge, M.S., de Graaff, M.J., Hagens, L.A., Haringman, J.J., van der Heide, S.T., van der Heiden, P.L.J., Heijnen, N.F.L., Hiel, S.J.P., Hoeijmakers, L.L., Hol, L., Hollmann, M.W., Hoogendoorn, M.E., Horn, J., van der Horst, R., Ie, E.L.K., Ivanov, D., Juffermans, N.P., Kho, E., de Klerk, E.S., Koopman-van Gemert, A.W.M.M., Koopmans, M., Kucukcelebi, S., Kuiper, M.A., de Lange, D.W., Martin-Loeches, I., Mazzinari, G., van Meenen, D.M.P., Morales-Quinteros, L., van Mourik, N., Nijbroek, S.G., Onrust, M., Oostdijk, E.A.N., Paulus, F., Pennartz, C.J., Pillay, J., Pisani, L., Purmer, I.M., Rettig, T.C.D., Roozeman, J.P., Schuijt, M.T.U., Schultz, M.J., Serpa Neto, A., Sleeswijk, M.E., Smit, M.R., Spronk, P.E., Stilma, W., Strang, A.C., Tsonas, A.M., Tuinman, P.R., Valk, C.M.A., Veen-Schra, F.L., Veldhuis, L.I., van Velzen, P., van der Ven, W.H., Vlaar, A.P.J., van Vliet, P., van der Voort, P.H.J., van Welie, L., Wesselink, H.J.F.T., van der Wier-Lubbers, H.H., van Wijk, B., Winters, T., Wong, W.Y., van Zanten, A.R.H.

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Reply to the Editor von Spronk, P.E., MD, PhD, Schultz, M.J., MD, PhD

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The fragility of statistically significant findings in randomised controlled anaesthesiology trials: systematic review of the medical literature von Mazzinari, G., Ball, L., Serpa Neto, A., Errando, C.L., Dondorp, A.M., Bos, L.D., Gama de Abreu, M., Pelosi, P., Schultz, M.J.

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Lung Microbiota of Critically Ill Patients with COVID-19 Are Associated with Nonresolving Acute Respiratory Distress Syndrome von Kullberg, Robert F J, de Brabander, Justin, Boers, Leonoor S, Biemond, Jason J, Nossent, Esther J, Heunks, Leo M A, Vlaar, Alexander P J, Bonta, Peter I, van der Poll, Tom, Duitman, JanWillem, Bos, Lieuwe D J, Wiersinga, W Joost

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Bronchoalveolar hemostasis in lung injury and acute respiratory distress syndrome von GLAS, G. J., VAN DER SLUIJS, K. F., SCHULTZ, M. J., HOFSTRA, J.‐J. H., VAN DER POLL, T., LEVI, M.

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Extensive pulmonary perfusion defects compatible with microthrombosis and thromboembolic disease in severe Covid-19 pneumonia von Beenen, L.F.M., Bos, L.D., Scheerder, M.J., Lobé, N.H.J., Muller, M.C.A., Schultz, M.J., van den Aardweg, J.G., Goorhuis, A., Bonta, P.I., Middeldorp, S., Vlaar, A.P.

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How doctors actually (do not) involve families in decisions to continue or discontinue life-sustaining treatment in neonatal, pediatric, and adult intensive care: A qualitative stu... von Akkermans, A. (Aranka), Lamerichs, J.M.W.J. (Joyce), Schultz, M.J. (Marcus), Cherpanath, T.G.V. (Thomas), van Woensel, J.B.M. (Job), van Heerde, M. (Marc), van Kaam, A.H.L.C. (Anton), van de Loo, M.D. (Moniek), Stiggelbout, A.M. (Anne), Smets, E.M.A. (Ellen), de Vos, M.A. (Mirjam)

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Fresh frozen plasma transfusion fails to influence the hemostatic balance in critically ill patients with a coagulopathy von Müller, M. C. A., Straat, M., Meijers, J. C. M., Klinkspoor, J. H., Jonge, E., Arbous, M. S., Schultz, M. J., Vroom, M. B., Juffermans, N. P.

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Ventilation and outcomes following robotic-assisted abdominal surgery: an international, multicentre observational study von Queiroz, Veronica N.F., da Costa, Luis Guilherme V., Takaoka, Flavio, de Abreu, Marcelo Gama, Schultz, Marcus J., Serpa Neto, Ary, Barbosa, R.P., Canet, J., Chaves, R.C.F., D’Orto, U.C., Galdi, J.R., Gama de Abreu, M., Hemmes, S.N.T., Posso, I.P., Queiroz, V.N.F., Schultz, M.J., Serpa Neto, A., Sprung, J., Takaoka, F., Vidal Melo, M.F., Agarwala, Aalok V., Akeroyd, Louise, Antonelli, Massimo, Arantes, Bruno S., Ariño Irujo, Jose J., Babian, Renata, Barker, Doug, Basagni, Diletta, Basso, Nicola, Beltran, Joan, Bocciero, Vittorio, Bonatti, Giulia, Boriati, Ernesto, Brazzi, Luca, Brearton, Chris, Brennan, Andrew, Bulinski, Adam M., Cesar, Daniel S., Chaves, Renato CF, Cilia, Danae, Cope, Sean, D’Orto, Ulisses C., Da Costa, Luis Guilherme V., Dalton, Claire, Davi, Alessandra, De Gaudio, Angelo Raffaele, De Luca, Lucilla, Deljou, Atousa, Droger, Sijgje M., Eidelman, Leonid A., Evans, Alison, Fabiani, Constanza, Fasciano, Umberto, Fitchett, Jillian, Fundarò, Angela, Galdi, Jose Roberto, Gallo, Verdiana, Gottumukkala, Vijaya, Graham, Chris, Granell Gil, Manuel, Gratarola, Angelo, Grillandini, Chiara, Groeben, Harald-Thomas, Jones, Chris, Jones, Rebecca, Kapoor, Ritoo, Köhne, Wiebke, Koopman, Joseph SHA, Liban, Bernard, Livi, Francesca, Martinez Plumed, Ruth, Matot, Idit, Mazzella, Marta, McClure, Stewart, McMonagle, Martina, Mills, Gary H., Monsalve, Concepción, Moon, Angela, Morris, Frances, Nerini, Alessandro, Orlandi, Marina, Paladini, Antonella, Patil, Anita, Patil, Vishal, Patrone, Valentina, Posso, Irimar P., Rabenalt, Robert, Romagnoli, Stefano, Ronen, Ariel, Rothman, Felipe, Russo, Andrea, Sabov, Moldovan, Shah, Nirav, Tena, Beatriz, Vanoverschelde, Henk, Vidal Melo, Marcos F., Villa, Gianluca, Weingarten, Toby N., Willcocks, Matt, Winslow, Luke

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Prognostication using SpO2/FiO2 in invasively ventilated ICU patients with ARDS due to COVID-19 – Insights from the PRoVENT-COVID study von Roozeman, Jan-Paul, Mazzinari, Guido, Serpa Neto, Ary, Hollmann, Markus W., Paulus, Frederique, Schultz, Marcus J., Pisani, Luigi, Algera, A.G., Boers, L.S., Bos, L.D.J., Botta, M., Dongelmans, D.A., Hollmann, M.W., Horn, J., Paulus, F., Pillay, J., Schultz, M.J., Neto, A. Serpa, Tsonas, A.M., Vlaar, A.P.J., Ahuja, S., van Akkeren, J.P., Algoe, C.K., van Amstel, R.B., Artigas, A., Baur, O.L., van de Berg, P., van den Berg, A.E., Bergmans, D.C.J.J., van den Bersselaar, D.I., Bertens, F.A., Bindels, A.J.G.H., de Boer, M.M., den Boer, S., Bogerd, M., Breel, J.S., de Bruin, H., de Bruin, S., Bruna, C.L., Buiteman-Kruizinga, L.A., Cremer, O.L., Determann, R.M., Dieperink, W., Franke, H.S., Galek-Aldridge, M.S., de Graaff, M.J., Hagens, L.A., Haringman, J.J., van der Heide, S.T., van der Heiden, P.L.J., Heijnen, N.F.L., Hiel, S.J.P., Hoeijmakers, L.L., Hol, L., Hoogendoorn, M.E., van der Horst, R., Ie, E.L.K., Ivanov, D., Juffermans, N.P., Kho, E., de Klerk, E.S., Gemert, A.W.M.M. Koopman-van, Koopmans, M., Kucukcelebi, S., Kuiper, M.A., de Lange, D.W., van Mourik, N., Nijbroek, S.G., Onrust, M., Oostdijk, E.A.N., Pennartz, C.J., Pisani, L., Purmer, I.M., Rettig, T.C.D., Roozeman, J.P., Schuijt, M.T.U., Sleeswijk, M.E., Smit, M.R., Spronk, P.E., Stilma, W., Strang, A.C., Tuinman, P.R., Valk, C.M.A., Veen-Schra, F.L., Veldhuis, L.I., van Velzen, P., van der Ven, W.H., van Vliet, P., van der Voort, P.H.J., van Welie, L., Wesselink, H.J.F.T., van der Wier-Lubbers, H.H., van Wijk, B., Winters, T., Wong, W.Y., van Zanten, A.R.H.

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Validity and reproducibility of a new method to estimate central blood pressure from the upper arm cuff oscillometric signal von Climie, R.E.D, Schultz, M.J, Nikolic, S.B, Ahuja, K.D.K, Fell, J.W, Sharman, J.E

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