Diagnosis and management of AML in adults: 2022 recommendations from an international expert panel on behalf of the ELN von Döhner, Hartmut, Wei, Andrew H, Appelbaum, Frederick R, Craddock, Charles, DiNardo, Courtney D, Dombret, Hervé, Ebert, Benjamin L, Fenaux, Pierre, Godley, Lucy A, Hasserjian, Robert P, Larson, Richard A, Levine, Ross L, Miyazaki, Yasushi, Niederwieser, Dietger, Ossenkoppele, Gert, Röllig, Christoph, Sierra, Jorge, Stein, Eytan M, Tallman, Martin S, Tien, Hwei-Fang, Wang, Jianxiang, Wierzbowska, Agnieszka, Löwenberg, Bob

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Revumenib for patients with acute leukemia: a new tool for differentiation therapy von Salman, Meira Yisraeli, Stein, Eytan M

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Enasidenib in mutant IDH2 relapsed or refractory acute myeloid leukemia von Stein, Eytan M., DiNardo, Courtney D., Pollyea, Daniel A., Fathi, Amir T., Roboz, Gail J., Altman, Jessica K., Stone, Richard M., DeAngelo, Daniel J., Levine, Ross L., Flinn, Ian W., Kantarjian, Hagop M., Collins, Robert, Patel, Manish R., Frankel, Arthur E., Stein, Anthony, Sekeres, Mikkael A., Swords, Ronan T., Medeiros, Bruno C., Willekens, Christophe, Vyas, Paresh, Tosolini, Alessandra, Xu, Qiang, Knight, Robert D., Yen, Katharine E., Agresta, Sam, de Botton, Stephane, Tallman, Martin S.

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Enasidenib induces acute myeloid leukemia cell differentiation to promote clinical response von Amatangelo, Michael D., Quek, Lynn, Shih, Alan, Stein, Eytan M., Roshal, Mikhail, David, Muriel D., Marteyn, Benoit, Farnoud, Noushin Rahnamay, de Botton, Stephane, Bernard, Olivier A., Wu, Bin, Yen, Katharine E., Tallman, Martin S., Papaemmanuil, Elli, Penard-Lacronique, Virginie, Thakurta, Anjan, Vyas, Paresh, Levine, Ross L.

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The DOT1L inhibitor pinometostat reduces H3K79 methylation and has modest clinical activity in adult acute leukemia von Stein, Eytan M., Garcia-Manero, Guillermo, Rizzieri, David A., Tibes, Raoul, Berdeja, Jesus G., Savona, Michael R., Jongen-Lavrenic, Mojca, Altman, Jessica K., Thomson, Blythe, Blakemore, Stephen J., Daigle, Scott R., Waters, Nigel J., Suttle, A. Benjamin, Clawson, Alicia, Pollock, Roy, Krivtsov, Andrei, Armstrong, Scott A., DiMartino, Jorge, Hedrick, Eric, Löwenberg, Bob, Tallman, Martin S.

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Which are the most promising targets for minimal residual disease-directed therapy in acute myeloid leukemia prior to allogeneic stem cell transplant? von Ball, Brian, Stein, Eytan M

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Acquired resistance to IDH inhibition through trans or cis dimer-interface mutations von Intlekofer, Andrew M., Shih, Alan H., Wang, Bo, Nazir, Abbas, Rustenburg, Ariën S., Albanese, Steven K., Patel, Minal, Famulare, Christopher, Correa, Fabian M., Takemoto, Naofumi, Durani, Vidushi, Liu, Hui, Taylor, Justin, Farnoud, Noushin, Papaemmanuil, Elli, Cross, Justin R., Tallman, Martin S., Arcila, Maria E., Roshal, Mikhail, Petsko, Gregory A., Wu, Bin, Choe, Sung, Konteatis, Zenon D., Biller, Scott A., Chodera, John D., Thompson, Craig B., Levine, Ross L., Stein, Eytan M.

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MEN1 mutations mediate clinical resistance to menin inhibition von Perner, Florian, Stein, Eytan M., Wenge, Daniela V., Singh, Sukrit, Kim, Jeonghyeon, Apazidis, Athina, Rahnamoun, Homa, Anand, Disha, Marinaccio, Christian, Hatton, Charlie, Wen, Yanhe, Stone, Richard M., Schaller, David, Mowla, Shoron, Xiao, Wenbin, Gamlen, Holly A., Stonestrom, Aaron J., Persaud, Sonali, Ener, Elizabeth, Cutler, Jevon A., Doench, John G., McGeehan, Gerard M., Volkamer, Andrea, Chodera, John D., Nowak, Radosław P., Fischer, Eric S., Levine, Ross L., Armstrong, Scott A., Cai, Sheng F.

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Coordinated alterations in RNA splicing and epigenetic regulation drive leukaemogenesis von Yoshimi, Akihide, Lin, Kuan-Ting, Wiseman, Daniel H., Rahman, Mohammad Alinoor, Pastore, Alessandro, Wang, Bo, Lee, Stanley Chun-Wei, Micol, Jean-Baptiste, Zhang, Xiao Jing, de Botton, Stephane, Penard-Lacronique, Virginie, Stein, Eytan M., Cho, Hana, Miles, Rachel E., Inoue, Daichi, Albrecht, Todd R., Somervaille, Tim C. P., Batta, Kiran, Amaral, Fabio, Simeoni, Fabrizio, Wilks, Deepti P., Cargo, Catherine, Intlekofer, Andrew M., Levine, Ross L., Dvinge, Heidi, Bradley, Robert K., Wagner, Eric J., Krainer, Adrian R., Abdel-Wahab, Omar

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Precision medicine treatment in acute myeloid leukemia using prospective genomic profiling: feasibility and preliminary efficacy of the Beat AML Master Trial von Burd, Amy, Levine, Ross L., Ruppert, Amy S., Mims, Alice S., Borate, Uma, Stein, Eytan M., Patel, Prapti, Baer, Maria R., Stock, Wendy, Deininger, Michael, Blum, William, Schiller, Gary, Olin, Rebecca, Litzow, Mark, Foran, James, Lin, Tara L., Ball, Brian, Boyiadzis, Michael, Traer, Elie, Odenike, Olatoyosi, Arellano, Martha, Walker, Alison, Duong, Vu. H., Kovacsovics, Tibor, Collins, Robert, Shoben, Abigail B., Heerema, Nyla A., Foster, Matthew C., Vergilio, Jo-Anne, Brennan, Tim, Vietz, Christine, Severson, Eric, Miller, Molly, Rosenberg, Leonard, Marcus, Sonja, Yocum, Ashley, Chen, Timothy, Stefanos, Mona, Druker, Brian, Byrd, John C.

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Molecularly targeted therapies for acute myeloid leukemia von Stein, Eytan M

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Isoform Switching as a Mechanism of Acquired Resistance to Mutant Isocitrate Dehydrogenase Inhibition von Harding, James J, Lowery, Maeve A, Shih, Alan H, Schvartzman, Juan M, Hou, Shengqi, Famulare, Christopher, Patel, Minal, Roshal, Mikhail, Do, Richard K, Zehir, Ahmet, You, Daoqi, Selcuklu, S Duygu, Viale, Agnes, Tallman, Martin S, Hyman, David M, Reznik, Ed, Finley, Lydia W S, Papaemmanuil, Elli, Tosolini, Alessandra, Frattini, Mark G, MacBeth, Kyle J, Liu, Guowen, Fan, Bin, Choe, Sung, Wu, Bin, Janjigian, Yelena Y, Mellinghoff, Ingo K, Diaz, Luis A, Levine, Ross L, Abou-Alfa, Ghassan K, Stein, Eytan M, Intlekofer, Andrew M

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Routine clinical parameters and laboratory testing predict therapy-related myeloid neoplasms after treatment for breast cancer von Petrone, Giulia, Gaulin, Charles, Derkach, Andriy, Kishtagari, Ashwin, Robson, Mark E, Parameswaran, Rekha, Stein, Eytan M

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Determinants of fatal bleeding during induction therapy for acute promyelocytic leukemia in the ATRA era von Mantha, Simon, Goldman, Debra A., Devlin, Sean M., Lee, Ju-Whei, Zannino, Diana, Collins, Marnie, Douer, Dan, Iland, Harry J., Litzow, Mark R., Stein, Eytan M., Appelbaum, Frederick R., Larson, Richard A., Stone, Richard, Powell, Bayard L., Geyer, Susan, Laumann, Kristina, Rowe, Jacob M., Erba, Harry, Coutre, Steven, Othus, Megan, Park, Jae H., Wiernik, Peter H., Tallman, Martin S.

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IDH2 inhibition in AML von Stein, Eytan M.

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Venetoclax and hypomethylating agents (HMAs) induce high response rates in MDS, including patients after HMA therapy failure von Ball, Brian J., Famulare, Christopher A., Stein, Eytan M., Tallman, Martin S., Derkach, Andriy, Roshal, Mikhail, Gill, Saar I., Manning, Benjamin M., Koprivnikar, Jamie, McCloskey, James, Testi, Rebecca, Prebet, Thomas, Al Ali, Najla H., Padron, Eric, Sallman, David A., Komrokji, Rami S., Goldberg, Aaron D.

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Investigational venetoclax combination therapy in acute myeloid leukemia - a systematic review and meta-analysis von Shimony, Shai, Rozental, Alon, Bewersdorf, Jan P, Goldberg, Aaron D, Stein, Eytan M, Grimshaw, Alyssa A, Stone, Richard M, DeAngelo, Daniel J, Wolach, Ofir, Stahl, Maximilian

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Cell-free DNA from nail clippings as source of normal control for genomic studies in hematologic malignancies von Krystel-Whittemore, Melissa, Petrova-Drus, Kseniya, Ptashkin, Ryan N, Ewalt, Mark D, Yao, JinJuan, Liu, Ying, Zhu, Menglei, Benhamida, Jamal, Durham, Benjamin, Kumar, Jyoti, Nafa, Khedoudja, Kiecka, Iwona, Bowman, Anita S, Gedvilaite, Erika, Casanova, Jacklyn, Lin, Yun-Te, Mohanty, Abhinita S, Rana, Satshil, Rema, Anoop Balakrishnan, Rijo, Ivelise, Chaves, Nelio, Salazar, Paulo, Yun, Anita, Lachhander, Sean, Wang, Wei, Haque, Mohammad S, Xiao, Wenbin, Roshal, Mikhail, Giralt, Sergio, Salles, Gilles, Rampal, Raajit, Stein, Eytan M, Perales, Miguel-Angel, Horwitz, Steven, Jakubowski, Ann, Ponce, Doris, Markova, Alina, Birsoy, Ozge, Mandelker, Diana, Mantha, Simon, Dogan, Ahmet, Benayed, Ryma, Ladanyi, Marc, Berger, Michael F, Brannon, A Rose, Zehir, Ahmet, Vanderbilt, Chad, Arcila, Maria E

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Emerging therapeutic drugs for AML von Stein, Eytan M., Tallman, Martin S.

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Molecular Pathways: IDH2 Mutations-Co-opting Cellular Metabolism for Malignant Transformation von Stein, Eytan M

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