Regulation of sphingosine kinase and sphingolipid signaling von Pitson, Stuart M.

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The Role of the Extracellular Matrix and Its Molecular and Cellular Regulators in Cancer Cell Plasticity von Poltavets, Valentina, Kochetkova, Marina, Pitson, Stuart M, Samuel, Michael S

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Roles, regulation and inhibitors of sphingosine kinase 2 von Neubauer, Heidi A, Pitson, Stuart M

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Resistance to proteasome inhibitors and other targeted therapies in myeloma von Wallington‐Beddoe, Craig T., Sobieraj‐Teague, Magdalena, Kuss, Bryone J., Pitson, Stuart M.

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Roles of lysophosphatidic acid and sphingosine-1-phosphate in stem cell biology von Lidgerwood, Grace E., Pitson, Stuart M., Bonder, Claudine, Pébay, Alice

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Mechanotransduction activates RhoA in the neighbors of apoptotic epithelial cells to engage apical extrusion von Duszyc, Kinga, Gomez, Guillermo A., Lagendijk, Anne K., Yau, Mei-Kwan, Nanavati, Bageshri Naimish, Gliddon, Briony L., Hall, Thomas E., Verma, Suzie, Hogan, Benjamin M., Pitson, Stuart M., Fairlie, David P., Parton, Robert G., Yap, Alpha S.

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Venetoclax therapy and emerging resistance mechanisms in acute myeloid leukaemia von Nwosu, Gus O., Ross, David M., Powell, Jason A., Pitson, Stuart M.

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Targeting the Sphingolipid System as a Therapeutic Direction for Glioblastoma von Tea, Melinda N, Poonnoose, Santosh I, Pitson, Stuart M

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Proteasomal degradation of sphingosine kinase 1 and inhibition of dihydroceramide desaturase by the sphingosine kinase inhibitors, SKi or ABC294640, induces growth arrest in androg... von McNaughton, Melissa, Pitman, Melissa, Pitson, Stuart M, Pyne, Nigel J, Pyne, Susan

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Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia von Powell, Jason A., Lewis, Alexander C., Zhu, Wenying, Toubia, John, Pitman, Melissa R., Wallington-Beddoe, Craig T., Moretti, Paul A.B., Iarossi, Diana, Samaraweera, Saumya E., Cummings, Nik, Ramshaw, Hayley S., Thomas, Daniel, Wei, Andrew H., Lopez, Angel F., D'Andrea, Richard J., Lewis, Ian D., Pitson, Stuart M.

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Characterising Distinct Migratory Profiles of Infiltrating T-Cell Subsets in Human Glioblastoma von Kollis, Paris M, Ebert, Lisa M, Toubia, John, Bastow, Cameron R, Ormsby, Rebecca J, Poonnoose, Santosh I, Lenin, Sakthi, Tea, Melinda N, Pitson, Stuart M, Gomez, Guillermo A, Brown, Michael P, Gargett, Tessa

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Overexpression of Sphingosine Kinase 1 Prevents Ceramide Accumulation and Ameliorates Muscle Insulin Resistance in High-Fat Diet―Fed Mice von BRUCE, Clinton R, RISIS, Steve, MEIKLE, Peter J, PITSON, Stuart M, FEBBRAIO, Mark A, BABB, Joanne R, YANG, Christine, KOWALSKI, Greg M, SELATHURAI, Ahrathy, LEE-YOUNG, Robert S, WEIR, Jacquelyn M, YOSHIOKA, Kazuaki, TAKUWA, Yoh

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Regulation of the hepatitis C virus RNA replicase by endogenous lipid peroxidation von Yamane, Daisuke, McGivern, David R, Wauthier, Eliane, Yi, MinKyung, Madden, Victoria J, Welsch, Christoph, Antes, Iris, Wen, Yahong, Chugh, Pauline E, McGee, Charles E, Widman, Douglas G, Misumi, Ichiro, Bandyopadhyay, Sibali, Kim, Seungtaek, Shimakami, Tetsuro, Oikawa, Tsunekazu, Whitmire, Jason K, Heise, Mark T, Dittmer, Dirk P, Kao, C Cheng, Pitson, Stuart M, Merrill, Alfred H, Reid, Lola M, Lemon, Stanley M

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FTY720 and (S)-FTY720 vinylphosphonate inhibit sphingosine kinase 1 and promote its proteasomal degradation in human pulmonary artery smooth muscle, breast cancer and androgen-inde... von Tonelli, Francesca, Lim, Keng Gat, Loveridge, Carolyn, Long, Jaclyn, Pitson, Stuart M., Tigyi, Gabor, Bittman, Robert, Pyne, Susan, Pyne, Nigel J.

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Disrupted epithelial/macrophage crosstalk via Spinster homologue 2-mediated S1P signaling may drive defective macrophage phagocytic function in COPD von Tran, Hai B, Jersmann, Hubertus, Truong, Tung Thanh, Hamon, Rhys, Roscioli, Eugene, Ween, Miranda, Pitman, Melissa R, Pitson, Stuart M, Hodge, Greg, Reynolds, Paul N, Hodge, Sandra

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Sphingosine Kinase 2 Promotes Acute Lymphoblastic Leukemia by Enhancing MYC Expression von WALLINGTON-BEDDOE, Craig T, POWELL, Jason A, DAOCHENTONG, PITSON, Stuart M, BRADSTOCK, Kenneth F, BENDALL, Linda J

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GD2-targeting CAR-T cells enhanced by transgenic IL-15 expression are an effective and clinically feasible therapy for glioblastoma von Gargett, Tessa, Ebert, Lisa M, Truong, Nga T H, Kollis, Paris M, Sedivakova, Kristyna, Yu, Wenbo, Yeo, Erica C F, Wittwer, Nicole L, Gliddon, Briony L, Tea, Melinda N, Ormsby, Rebecca, Poonnoose, Santosh, Nowicki, Jake, Vittorio, Orazio, Ziegler, David S, Pitson, Stuart M, Brown, Michael P

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The sphingosine 1-phosphate receptor 2/4 antagonist JTE-013 elicits off-target effects on sphingolipid metabolism von Pitman, Melissa R., Lewis, Alexander C., Davies, Lorena T., Moretti, Paul A. B., Anderson, Dovile, Creek, Darren J., Powell, Jason A., Pitson, Stuart M.

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Resensitising proteasome inhibitor-resistant myeloma with sphingosine kinase 2 inhibition von Bennett, Melissa K., Li, Manjun, Tea, Melinda N., Pitman, Melissa R., Toubia, John, Wang, Paul P.-S., Anderson, Dovile, Creek, Darren J., Orlowski, Robert Z., Gliddon, Briony L., Powell, Jason A., Wallington-Beddoe, Craig T., Pitson, Stuart M.

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Targeting the integrated stress response in hematologic malignancies von Nwosu, Gus O, Powell, Jason A, Pitson, Stuart M

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