Cross-Coupling Methods for the Large-Scale Preparation of an Imidazole−Thienopyridine:  Synthesis of [2-(3-Methyl-3H-imidazol-4-yl)- thieno[3,2-b]pyridin-7-yl]-(2-methyl-1H-indol-5... von Ragan, J. A, Raggon, J. W, Hill, P. D, Jones, B. P, McDermott, R. E, Munchhof, M. J, Marx, M. A, Casavant, J. M, Cooper, B. A, Doty, J. L, Lu, Y

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Design and SAR of thienopyrimidine and thienopyridine inhibitors of VEGFR-2 kinase activity von Munchhof, Michael J., Beebe, Jean S., Casavant, Jeffery M., Cooper, Beth A., Doty, Jonathan L., Higdon, R.Carla, Hillerman, Stephen M., Soderstrom, Catherine I., Knauth, Elisabeth A., Marx, Matthew A., Rossi, Ann Marie K., Sobolov, Susan B., Sun, Jianmin

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The stereochemistry of enolate formation in THF-hexane mixtures von Munchhof, Michael J., Heathcock, Clayton H.

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A Novel Asymmetric Route to Chiral, Nonracemic cis-2,6-Disubstituted Piperidines. Synthesis of (+)-Pinidinone and (+)-Monomorine von Munchhof, Michael J, Meyers, A. I

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An Asymmetric Route to Chiral, Nonracemic 2-Substituted Piperidines. Synthesis of (-)-Pipecoline, (+)-Coniine, and (-)-Coniceine von Munchhof, Michael J, Meyers, A. I

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A Novel Asymmetric Route to the 1,3-Disubstituted Tetrahydroisoquinoline, (−)-Argemonine von Munchhof, Michael J, Meyers, A. I

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PYRAZINVERBINDUNGEN ALS INHIBITOREN DES TRANSFORMING GROWTH FACTOR (TGF) von MUNCHHOF, M. J

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PYRAZINE COMPOUNDS AS TRANSFORMING GROWTH FACTOR (TGF) INHIBITORS von MUNCHHOF, M. J

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PYRAZINE COMPOUNDS AS TRANSFORMING GROWTH FACTOR (TGF) INHIBITORS von MUNCHHOF, M. J

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COMPUESTOS DE PIRAZINA COMO INHIBIDORES DEL FACTOR DE CRECIMIENTO TRANSFORMANTE (TGF) von MUNCHHOF, M. J

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Pyrrolo [2, 3-d] pyrimidine compounds von M. J. MUNCHHOF, M. E. FLANAGAN, T. A. BLUMENKOPF

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Pyrrolo [2,3-d] pyrimidine compounds von M. J. MUNCHHOF, M. E. FLANAGAN, T. A. BLUMENKOPF

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A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models von Chan-Penebre, Elayne, Kuplast, Kristy G, Majer, Christina R, Boriack-Sjodin, P Ann, Wigle, Tim J, Johnston, L Danielle, Rioux, Nathalie, Munchhof, Michael J, Jin, Lei, Jacques, Suzanne L, West, Kip A, Lingaraj, Trupti, Stickland, Kimberly, Ribich, Scott A, Raimondi, Alejandra, Scott, Margaret Porter, Waters, Nigel J, Pollock, Roy M, Smith, Jesse J, Barbash, Olena, Pappalardi, Melissa, Ho, Thau F, Nurse, Kelvin, Oza, Khyati P, Gallagher, Kathleen T, Kruger, Ryan, Moyer, Mikel P, Copeland, Robert A, Chesworth, Richard, Duncan, Kenneth W

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Structure and Property Guided Design in the Identification of PRMT5 Tool Compound EPZ015666 von Duncan, Kenneth W, Rioux, Nathalie, Boriack-Sjodin, P. Ann, Munchhof, Michael J, Reiter, Lawrence A, Majer, Christina R, Jin, Lei, Johnston, L. Danielle, Chan-Penebre, Elayne, Kuplast, Kristy G, Porter Scott, Margaret, Pollock, Roy M, Waters, Nigel J, Smith, Jesse J, Moyer, Mikel P, Copeland, Robert A, Chesworth, Richard

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Discovery of a First-in-Class Inhibitor of the Histone Methyltransferase SETD2 Suitable for Preclinical Studies von Lampe, John W, Alford, Joshua S, Boriak-Sjodin, P. Ann, Brach, Dorothy, Cosmopoulos, Kat, Duncan, Kenneth W, Eckley, Sean T, Foley, Megan A, Harvey, Darren M, Motwani, Vinny, Munchhof, Michael J, Raimondi, Alejandra, Riera, Thomas V, Tang, Cuyue, Thomenius, Michael J, Totman, Jennifer, Farrow, Neil A

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GLI2 inhibition abrogates human leukemia stem cell dormancy von Sadarangani, Anil, Pineda, Gabriel, Lennon, Kathleen M, Chun, Hye-Jung, Shih, Alice, Schairer, Annelie E, Court, Angela C, Goff, Daniel J, Prashad, Sacha L, Geron, Ifat, Wall, Russell, McPherson, John D, Moore, Richard A, Pu, Minya, Bao, Lei, Jackson-Fisher, Amy, Munchhof, Michael, VanArsdale, Todd, Reya, Tannishtha, Morris, Sheldon R, Minden, Mark D, Messer, Karen, Mikkola, Hanna K A, Marra, Marco A, Hudson, Thomas J, Jamieson, Catriona H M

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The specificity of JAK3 kinase inhibitors von Changelian, Paul S., Moshinsky, Deborah, Kuhn, Cyrille F., Flanagan, Mark E., Munchhof, Michael J., Harris, Thomas M., Whipple, David A., Doty, Jonathan L., Sun, Jianmin, Kent, Craig R., Magnuson, Kelly S., Perregaux, David G., Sawyer, Perry S., Kudlacz, Elizabeth M.

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Discovery of CP-690,550: A Potent and Selective Janus Kinase (JAK) Inhibitor for the Treatment of Autoimmune Diseases and Organ Transplant Rejection von Flanagan, Mark E, Blumenkopf, Todd A, Brissette, William H, Brown, Matthew F, Casavant, Jeffrey M, Shang-Poa, Chang, Doty, Jonathan L, Elliott, Eileen A, Fisher, Michael B, Hines, Michael, Kent, Craig, Kudlacz, Elizabeth M, Lillie, Brett M, Magnuson, Kelly S, McCurdy, Sandra P, Munchhof, Michael J, Perry, Bret D, Sawyer, Perry S, Strelevitz, Timothy J, Subramanyam, Chakrapani, Sun, Jianmin, Whipple, David A, Changelian, Paul S

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Small molecule inhibitors and CRISPR/Cas9 mutagenesis demonstrate that SMYD2 and SMYD3 activity are dispensable for autonomous cancer cell proliferation von Thomenius, Michael J, Totman, Jennifer, Harvey, Darren, Mitchell, Lorna H, Riera, Thomas V, Cosmopoulos, Kat, Grassian, Alexandra R, Klaus, Christine, Foley, Megan, Admirand, Elizabeth A, Jahic, Haris, Majer, Christina, Wigle, Tim, Jacques, Suzanne L, Gureasko, Jodi, Brach, Dorothy, Lingaraj, Trupti, West, Kip, Smith, Sherri, Rioux, Nathalie, Waters, Nigel J, Tang, Cuyue, Raimondi, Alejandra, Munchhof, Michael, Mills, James E, Ribich, Scott, Porter Scott, Margaret, Kuntz, Kevin W, Janzen, William P, Moyer, Mikel, Smith, Jesse J, Chesworth, Richard, Copeland, Robert A, Boriack-Sjodin, P Ann

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A Rational Chemical Intervention Strategy To Circumvent Bioactivation Liabilities Associated with a Nonpeptidyl Thrombopoietin Receptor Agonist Containing a 2-Amino-4-arylthiazole... von Kalgutkar, Amit S, Driscoll, James, Zhao, Sabrina X, Walker, Gregory S, Shepard, Richard M, Soglia, John R, Atherton, James, Yu, Linning, Mutlib, Abdul E, Munchhof, Michael J, Reiter, Lawrence A, Jones, Christopher S, Doty, Johnathan L, Trevena, Kristen A, Shaffer, Christopher L, Ripp, Sharon L

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