MLL5 improves ATRA driven differentiation and promotes xenotransplant engraftment in acute promyelocytic leukemia model von Pereira-Martins, Diego A., Weinhäuser, Isabel, Coelho-Silva, Juan Luiz, França-Neto, Pedro L., Almeida, Luciana Y., Bianco, Thiago M., Silva, Cleide L., França, Rafael F., Traina, Fabiola, Rego, Eduardo M., Schuringa, Jan Jacob, Lucena-Araujo, Antonio R.

Volltext

The influence of physical activity in the anti-tumor immune response in experimental breast tumor von Bianco, Thiago M., Abdalla, Douglas R., Desidério, Chamberttan S., Thys, Sofie, Simoens, Cindy, Bogers, John-Paul, Murta, Eddie F.C., Michelin, Márcia A.

Volltext

M2 macrophages drive leukemic transformation by imposing resistance to phagocytosis and improving mitochondrial metabolism von Weinhäuser, Isabel, Pereira-Martins, Diego A, Almeida, Luciana Y, Hilberink, Jacobien R, Silveira, Douglas R A, Quek, Lynn, Ortiz, Cesar, Araujo, Cleide L, Bianco, Thiago M, Lucena-Araujo, Antonio, Mota, Jose Mauricio, Hogeling, Shanna M, Sternadt, Dominique, Visser, Nienke, Diepstra, Arjan, Ammatuna, Emanuele, Huls, Gerwin, Rego, Eduardo M, Schuringa, Jan Jacob

Volltext

P466: THE INTRINSICALLY DISORDERED TRANSCRIPTIONAL REGULATOR MN1 DEPENDS ON THE CHAPERONE DNAJB6B FOR ITS FULL TRANSFORMING POTENTIAL von Pereira‐Martins, Diego A, Boom, Vincent, Dijk, Noortje, Weinhauser, Isabel, Silveira, Douglas, M Bianco, Thiago, Alexander Ortiz Rojas, César, Huls, Gerwin, Quek, Lynn, R Lucena‐Araujo, Antonio, Rego, Eduardo, Jacob Schuringa, Jan

Volltext

S127: DELTATP73 IMPOSES TP53 MUTANT‐LIKE PHENOTYPES INCLUDING DRUG RESISTANCE AND POOR PROGNOSIS ON TP53‐WILD TYPE ACUTE MYELOID LEUKEMIA von Pereira‐Martins, Diego A, Alexander Ortiz Rojas, César, Weinhauser, Isabel, Silveira, Douglas, Wierenga, Albertus T J, Boom, Vincent, Bianco, Thiago M, Ammatuna, Emanuele, Quek, Lynn, Lucena‐Araujo, Antonio R, Huls, Gerwin, Rego, Eduardo, Jacob Schuringa, Jan

Volltext

Reduced SLIT2 is Associated with Increased Cell Proliferation and Arsenic Trioxide Resistance in Acute Promyelocytic Leukemia von Weinhauser, Isabel, Pereira-Martins, Diego A., Ortiz, Cesar, Silveira, Douglas R., Simoes, Luise A. A., Bianco, Thiago M., Araujo, Cleide L., Koury, Luisa C., Melo, Raul A. M., Bittencourt, Rosane I., Pagnano, Katia, Pasquini, Ricardo, Nunes, Elenaide C., Fagundes, Evandro M., Gloria, Ana B., Kerbauy, Fabio, Chauffaille, Maria de Lourdes, Keating, Armand, Tallman, Martin S., Ribeiro, Raul C., Dillon, Richard, Ganser, Arnold, Lowenberg, Bob, Valk, Peter, Lo-Coco, Francesco, Sanz, Miguel A., Berliner, Nancy, Ammatuna, Emanuele, Lucena-Araujo, Antonio R., Schuringa, Jan Jacob, Rego, Eduardo M.

Volltext

High MN1 Expression Is Associated with an Lspc-Enriched Phenotype and Glycolysis Representing a New Vulnerability in Acute Myeloid Leukemia von Pereira-Martins, Diego, van Dijk, Noortje, Weinhaeuser, Isabel, Silveira, Douglas RA, Coelho Da Silva, Juan, Bianco, Thiago M, Ortiz, César Alexander, Traina, Fabiola, Figueiredo-Pontes, Lorena L, Ammatuna, Emanuele, Quek, Lynn, Huls, Gerwin A., Lucena-Araujo, Antonio R., Rego, Eduardo M, Schuringa, Jan Jacob

Volltext

Overdose death rates in Brazil: an ecological analysis by region von Tardelli, Vitor S, Bianco, Marina C M, Patel, Rachel, Areco, Kelsy C N, Bandiera-Paiva, Paulo, Tardelli, Adalberto O, Segura, Luis E, Castaldelli-Maia, João M, Fidalgo, Thiago M, Martins, Silvia S

Volltext

Overdose deaths involving non-BZD hypnotic/sedatives in the USA: Trends analyses von Tardelli, Vitor S., Bianco, Marina C.M., Prakash, Rashmika, Segura, Luis E., Castaldelli-Maia, João M., Fidalgo, Thiago M., Martins, Silvia S.

Volltext

Drug overdose deaths in Brazil between 2000 and 2020: an analysis of sociodemographics and intentionality von Bianco, Marina Costa Moreira, Tardelli, Vitor S, Brooks, Emily Rose, Areco, Kelsy C N, Tardelli, Adalberto O, Bandiera-Paiva, Paulo, Santaella, Julian, Segura, Luis E, Castaldelli-Maia, João M, Martins, Silvia S, Fidalgo, Thiago M

Volltext

No space for all-or-nothing in epidemiology: The art of parsimony and interpretation – Authors’ reply von Tardelli, Vitor S., Bianco, Marina C.M., Prakash, Rashmika, Segura, Luis E., Castaldelli-Maia, João M., Fidalgo, Thiago M., Martins, Silvia S.

Volltext

Mice born to females with oocyte-specific deletion of mitofusin 2 have increased weight gain and impaired glucose homeostasis von Garcia, Bruna M, Machado, Thiago S, Carvalho, Karen F, Nolasco, Patrícia, Nociti, Ricardo P, del Collado, Maite, Capo Bianco, Maria J D, Grejo, Mateus P, Augusto Neto, José Djaci, Sugiyama, Fabrícia H C, Tostes, Katiane, Pandey, Anand K, Gonçalves, Luciana M, Perecin, Felipe, Meirelles, Flávio V, Ferraz, José Bento S, Vanzela, Emerielle C, Boschero, Antônio C, Guimarães, Francisco E G, Abdulkader, Fernando, Laurindo, Francisco R M, Kowaltowski, Alicia J, Chiaratti, Marcos R

Volltext

Larvicidal activity of seaweeds from northeastern Brazil and of a halogenated sesquiterpene against the dengue mosquito (Aedes aegypti) von Bianco, Everson M., Pires, Luana, Santos, Geanne K.N., Dutra, Kamilla A., Reis, Thiago N.V., Vasconcelos, Edson R.T.P.P., Cocentino, Adilma L.M., Navarro, Daniela M.A.F.

Volltext

Treatment with the Recombinant SLIT2 Protein Delays AML Leukemogenesis In Vivo von Simoes, Luise A de Albuquerque, Weinhäuser, Isabel, Pereira-Martins, Diego A, Ortiz Rojas, César Alexander, Bianco, Thiago Mantello, Cavaglieri, Rita de Cassia, Rego, Eduardo M

Volltext

Photoprotective activity and increase of SPF in sunscreen formulation using lyophilized red propolis extracts from Alagoas von Almeida, Wanessa A. da S., Antunes, Amanda dos Santos, Penido, Ricardo G., Correa, Helen S. da G., Nascimento, Andrea M. do, Andrade, Ângela L., Santos, Vagner R., Cazati, Thiago, Amparo, Tatiane Roquete, Souza, Gustavo Henrique Bianco de, Freitas, Kátia Michelle, Santos, Orlando David Henrique dos, Sousa, Lucas Resende Dutra, Santos, Viviane M. R. dos

Volltext

Reduced SLIT2 Are Associated with Increased Cell Proliferation and Arsenic Trioxide Resistance in APL Cells von Weinhäuser, Isabel, Pereira-Martins, Diego A, Simões, Luíse A A, Ortiz Rojas, César Alexander, Bianco, Thiago Mantello, Silva, Cleide Lucia, Do Nascimento, Mariane Cristina, Figueiredo-Pontes, Lorena Lobo, Lucena-Araujo, Antonio R., Rego, Eduardo M

Volltext

Metformin Suppress Cellular and Molecular Processes Related to Maintenance and Proliferation of Myeloproliferative Neoplasm Stem Cell von Coelho-Silva, Juan L, Bianco, Thiago Mantello, Silva, Antonio Bruno Alves, Pereira-Martins, Diego Antonio, Fonseca, Natasha Peixoto, Weinhäuser, Isabel, Rego, Eduardo M, Chahud, Fernando, Machado-Neto, João Agostinho, Figueiredo-Pontes, Lorena Lobo, Traina, Fabiola

Volltext

Efficacy of the Pan-Bcl-2 Inhibitor (Obatoclax) As a Single Agent to Treat Myeloproliferative Neoplasm in JAK2V617F Murine Transplantation Model von Bianco, Thiago Mantello, Coelho-Silva, Juan L, Pereira-Martins, Diego A, Scheucher, Priscila Santos, Weinhäuser, Isabel, Silva, Antonio Bruno Alves, Silva, Cleide Lucia, Mullally, Ann, Kobayashi, Susumu S, Rego, Eduardo M, Traina, Fabiola, Figueiredo-Pontes, Lorena Lobo

Volltext

Clinical and Functional Studies Reveal That TP73 Isoforms Levels Are Associated with Prognosis and RA-Resistance in Acute Promyelocytic Leukemia von Ortiz Rojas, César Alexander, Pereira-Martins, Diego A, Weinhäuser, Isabel, Almeida, Luciana Yamamoto, Bianco, Thiago Mantello, Figueiredo-Pontes, Lorena Lobo, Koury, Luisa C A, Melo, Raul Antônio Morais, Bittencourt, Rosane, Pagnano, Katia B, Pasquini, Ricardo, Nunes, Elenaide C., Fagundes, Evandro Maranhão, Gloria, Ana Beatriz F., Kerbauy, Fabio R., Keating, Armand, Tallman, Martin S., Ribeiro, Raul, Dillon, Richard, Ganser, Arnold, Löwenberg, Bob, Valk, Peter, Sanz, Miguel A., Berliner, Nancy, Rego, Eduardo M

Volltext

Overdose death rates in Brazil: an ecological analysis by region von Tardelli, Vitor S., Bianco, Marina C.M., Patel, Rachel, Areco, Kelsy C.N., Bandiera-Paiva, Paulo, Tardelli, Adalberto O., Segura, Luis E., Castaldelli-Maia, João M., Fidalgo, Thiago M., Martins, Silvia S.

Volltext