The determination and interpretation of the therapeutic index in drug development von Muller, Patrick Y., Milton, Mark N.

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Secondary pharmacology: screening and interpretation of off-target activities – focus on translation von Whitebread, Steven, Dumotier, Berengere, Armstrong, Duncan, Fekete, Alexander, Chen, Shanni, Hartmann, Andreas, Muller, Patrick Y., Urban, Laszlo

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Safety and immunotoxicity assessment of immunomodulatory monoclonal antibodies von Brennan, Frank R., Morton, Laura Dill, Spindeldreher, Sebastian, Kiessling, Andrea, Allenspach, Roy, Hey, Adam, Müller, Patrick, Frings, Werner, Sims, Jennifer

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Processing of gene expression data generated by quantitative real-time RT-PCR von MULLER, Patrick Y, JANOVJAK, Harald, MISEREZ, André R, DOBBIE, Zuzana

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The minimum anticipated biological effect level (MABEL) for selection of first human dose in clinical trials with monoclonal antibodies von Muller, Patrick Y, Milton, Mark, Lloyd, Peter, Sims, Jennifer, Brennan, Frank R

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Comparative requirements for exploratory clinical trials — eIND, eCTA and microdosing von Muller, Patrick Y.

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Integrated risk assessment of suicidal ideation and behavior in drug development von Muller, Patrick Y., Dambach, Donna, Gemzik, Brian, Hartmann, Andreas, Ratcliffe, Sian, Trendelenburg, Christian, Urban, Laszlo

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Tissue-specific, non-invasive toxicity biomarkers: translation from preclinical safety assessment to clinical safety monitoring von Muller, Patrick Y, Dieterle, Frank

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Safety differentiation: emerging competitive edge in drug development von Uteng, Marianne, Urban, Laszlo, Brees, Dominique, Muller, Patrick Y., Kullak-Ublick, Gerd A., Bouchard, Page, Tougas, Gervais, Chibout, Salah-Dine

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A single-nucleotide polymorphism in the sterol-regulatory element-binding protein 1c gene is predictive of HIV-related hyperlipoproteinaemia von MISEREZ, André R, MULLER, Patrick Y, BARELLA, Luca, SCHWIETERT, Martin, ERB, Peter, VERNAZZA, Pietro L, BATTEGAY, Manuel

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Identification of hepatic molecular mechanisms of action of alpha-tocopherol using global gene expression profile analysis in rats von Barella, Luca, Muller, Patrick Y, Schlachter, Manfred, Hunziker, Willi, Stöcklin, Elisabeth, Spitzer, Volker, Meier, Nina, de Pascual-Teresa, Sonia, Minihane, Anne-Marie, Rimbach, Gerald

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Molecular BioComputing Suite: A word processor add-in for the analysis and manipulation of nucleic acid and protein sequence data von MULLER, Patrick Y, STUDER, Etienne, MISEREZ, André R

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Indinavir inhibits sterol-regulatory element-binding protein-1c-dependent lipoprotein lipase and fatty acid synthase gene activations von Miserez, André R, Muller, Patrick Y, Spaniol, Violeta

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RepGene : A spreadsheet template for the management of reporter gene assays von MULLER, Patrick Y, BARELLA, Luca, MISEREZ, André R

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Comparative quantification of pharmacodynamic parameters of chiral compounds ( RRR- vs. all-rac- α tocopherol) by global gene expression profiling von Muller, Patrick Y., Netscher, Thomas, Frank, Jan, Stoecklin, Elisabeth, Rimbach, Gerald, Barella, Luca

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Comparative requirements for exploratory clinical trials — eIND, eCTA and microdosing: NEW STRATEGY FOR DRUG DEVELOPMENT WITH EXPLORATORY IND STUDIES: SCIENTIFIC BASIS AND FUTURE D... von MULLER, Patrick Y

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Sterol-regulatory element-binding protein (SREBP)-2 contributes to polygenic hypercholesterolaemia von Miserez, André R., Muller, Patrick Y., Barella, Luca, Barella, Sandra, Staehelin, Hannes B., Leitersdorf, Eran, Kark, Jeremy D., Friedlander, Yechiel

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Targets Associated with Drug‐Related Suicidal Ideation and Behavior von Hartmann, Andreas, Whitebread, Steven, Hamon, Jacques, Fekete, Alexander, Trendelenburg, Christian, Müller, Patrick Y, Urbán, László

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Safety differentiation: emerging competitive edge in drug development von Uteng, Marianne, Urban, Laszlo, Brees, Dominique, Muller, Patrick Y, Kullak-Ublick, Gerd A, Bouchard, Page, Tougas, Gervais, Chibout, Salah-Dine

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Familial defective apolipoprotein B-100: a mutation emerged in the Mesolithic ancestors of Celtic peoples? von Miserez, André R, Muller, Patrick Y

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