Targeting the vulnerability to NAD+ depletion in B-cell acute lymphoblastic leukemia von Takao, S, Chien, W, Madan, V, Lin, D-C, Ding, L-W, Sun, Q-Y, Mayakonda, A, Sudo, M, Xu, L, Chen, Y, Jiang, Y-Y, Gery, S, Lill, M, Park, E, Senapedis, W, Baloglu, E, Müschen, M, Koeffler, H P

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Phosphorylation of a constrained azacyclic FTY720 analog enhances anti-leukemic activity without inducing S1P receptor activation von McCracken, A N, McMonigle, R J, Tessier, J, Fransson, R, Perryman, M S, Chen, B, Keebaugh, A, Selwan, E, Barr, S A, Kim, S M, Roy, S G, Liu, G, Fallegger, D, Sernissi, L, Brandt, C, Moitessier, N, Snider, A J, Clare, S, Müschen, M, Huwiler, A, Kleinman, M T, Hanessian, S, Edinger, A L

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Small-molecule inhibition of CBP/catenin interactions eliminates drug-resistant clones in acute lymphoblastic leukemia von Gang, E J, Hsieh, Y-T, Pham, J, Zhao, Y, Nguyen, C, Huantes, S, Park, E, Naing, K, Klemm, L, Swaminathan, S, Conway, E M, Pelus, L M, Crispino, J, Mullighan, C G, McMillan, M, Müschen, M, Kahn, M, Kim, Y-M

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Pre-BCR signaling in precursor B-cell acute lymphoblastic leukemia regulates PI3K/AKT, FOXO1 and MYC, and can be targeted by SYK inhibition von Köhrer, S, Havranek, O, Seyfried, F, Hurtz, C, Coffey, G P, Kim, E, ten Hacken, E, Jäger, U, Vanura, K, O'Brien, S, Thomas, D A, Kantarjian, H, Ghosh, D, Wang, Z, Zhang, M, Ma, W, Jumaa, H, Debatin, K-M, Müschen, M, Meyer, L H, Davis, R E, Burger, J A

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BCOR regulates myeloid cell proliferation and differentiation von Cao, Q, Gearhart, M D, Gery, S, Shojaee, S, Yang, H, Sun, H, Lin, D-c, Bai, J-w, Mead, M, Zhao, Z, Chen, Q, Chien, W-w, Alkan, S, Alpermann, T, Haferlach, T, Müschen, M, Bardwell, V J, Koeffler, H P

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Development of resistance to dasatinib in Bcr Abl-positive acute lymphoblastic leukemia von Fei, F, Stoddart, S, Müschen, M, Kim, Y-m, Groffen, J, Heisterkamp, N

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VPREB1 deletions occur independent of lambda light chain rearrangement in childhood acute lymphoblastic leukemia von Mangum, D S, Downie, J, Mason, C C, Jahromi, M S, Joshi, D, Rodic, V, Müschen, M, Meeker, N, Trede, N, Frazer, J K, Zhou, Y, Cheng, C, Jeha, S, Pui, C-H, Willman, C L, Harvey, R C, Hunger, S P, Yang, J J, Barnette, P, Mullighan, C G, Miles, R R, Schiffman, J D

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BCR-ABL1 induces aberrant splicing of IKAROS and lineage infidelity in pre-B lymphoblastic leukemia cells von KLEIN, F, FELDHAHN, N, HERZOG, S, SPRANGERS, M, MOOSTER, J. L, JUMAA, H, MÜSCHEN, M

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Immunoglobulin class-switch recombination occurs in mantle cell lymphomas von Klapper, W, Szczepanowski, M, Heidorn, K, Müschen, M, Liedtke, S, Sotnikova, A, Andersen, NS, Greeve, J, Parwaresch, R

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Epigenetic regulation of gene expression by Ikaros, HDAC1 and Casein Kinase II in leukemia von Song, C, Pan, X, Ge, Z, Gowda, C, Ding, Y, Li, H, Li, Z, Yochum, G, Muschen, M, Li, Q, Payne, K J, Dovat, S

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ABL fusion oncogene transformation and inhibitor sensitivity are mediated by the cellular regulator RIN1 von Thai, M, Ting, P Y, McLaughlin, J, Cheng, D, Müschen, M, Witte, O N, Colicelli, J

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Somatic mutation of the CD95 gene in human B cells as a side-effect of the germinal center reaction von Müschen, M, Re, D, Jungnickel, B, Diehl, V, Rajewsky, K, Küppers, R

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Rare occurrence of classical Hodgkin's disease as a T cell lymphoma von Müschen, M, Rajewsky, K, Bräuninger, A, Baur, A S, Oudejans, J J, Roers, A, Hansmann, M L, Küppers, R

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Defining CD95 as a tumor suppressor gene von MÜSCHEN, M, WARSKULAT, U, BECKMANN, M. W

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A critical role for transforming growth factor-beta in donor transfusion-induced allograft tolerance von Josien, R, Douillard, P, Guillot, C, Müschen, M, Anegon, I, Chetritt, J, Menoret, S, Vignes, C, Soulillou, J P, Cuturi, M C

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Oct-2 and Bob-1 deficiency in Hodgkin and Reed Sternberg cells von RE, Daniel, MIISCHEN, Markus, AHMADI, Tahamtan, WICKENHAUSER, Claudia, STARATSCHEK-JOX, Andrea, HOLTICK, Udo, DIEHL, Volker, WOLF, Jürgen

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SLP65 deficiency results in perpetual V(D)J recombinase activity in pre-B-lymphoblastic leukemia and B-cell lymphoma cells von Sprangers, M, Feldhahn, N, Liedtke, S, Jumaa, H, Siebert, R, Müschen, M

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Somatic mutations of the CD95 gene in hodgkin and Reed-Sternberg cells von MÜSCHEN, Markus, RE, Daniel, BRÄUNINGER, Andreas, WOLF, Jürgen, HANSMANN, Martin-Leo, DIEHL, Volker, KÜPPERS, Ralf, RAJEWSKY, Klaus

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Novel BAFF‐R CAR T‐cell Therapy for CD19 Antigen‐loss Relapsed B Cell Tumors von Kwak, L.W., Qin, H., Dong, Z., Wang, X., Cheng, W.A., Smith, D., Song, J.Y., Aldoss, I., Muschen, M., Forman, S.J.

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A new human somatic stem cell from placental cord blood with intrinsic pluripotent differentiation potential von Kögler, Gesine, Sensken, Sandra, Airey, Judith A, Trapp, Thorsten, Müschen, Markus, Feldhahn, Niklas, Liedtke, Stefanie, Sorg, Rüdiger V, Fischer, Johannes, Rosenbaum, Claudia, Greschat, Susanne, Knipper, Andreas, Bender, Jörg, Degistirici, Ozer, Gao, Jizong, Caplan, Arnold I, Colletti, Evan J, Almeida-Porada, Graça, Müller, Hans W, Zanjani, Esmail, Wernet, Peter

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