Crystal Structure of the Polyketide Cyclase AknH with Bound Substrate and Product Analogue: Implications for Catalytic Mechanism and Product Stereoselectivity von Kallio, Pauli, Sultana, Azmiri, Niemi, Jarmo, Mäntsälä, Pekka, Schneider, Gunter

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Structure of the polyketide cyclase SnoaL reveals a novel mechanism for enzymatic aldol condensation von Sultana, Azmiri, Kallio, Pauli, Jansson, Anna, Wang, Ji-Shu, Niemi, Jarmo, Mäntsälä, Pekka, Schneider, Gunter

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Nucleotide sequences and expression of genes from Streptomyces purpurascens that cause the production of new anthracyclines in Streptomyces galilaeus von Niemi, J, Mäntsälä, P

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Crystal Structure of a Ternary Complex of DnrK, a Methyltransferase in Daunorubicin Biosynthesis, with Bound Products von Jansson, Anna, Koskiniemi, Hanna, Mäntsälä, Pekka, Niemi, Jarmo, Schneider, Gunter

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Cloning and sequence of Bacillus subtilis purA and guaA, involved in the conversion of IMP to AMP and GMP von Mantsala, Pekka, Zalkin, Howard

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Crystal structure of aclacinomycin methylesterase with bound product analogues: implications for anthracycline recognition and mechanism von Jansson, Anna, Niemi, Jarmo, Mäntsälä, Pekka, Schneider, Gunter

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Aclacinomycin 10-Hydroxylase Is a Novel Substrate-assisted Hydroxylase Requiring S-Adenosyl-l-methionine as Cofactor von Jansson, Anna, Koskiniemi, Hanna, Erola, Anna, Wang, Jessy, Mäntsälä, Pekka, Schneider, Gunter, Niemi, Jarmo

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The entire nogalamycin biosynthetic gene cluster of Streptomyces nogalater: characterization of a 20-kb DNA region and generation of hybrid structures von Torkkell, S, Kunnari, T, Palmu, K, Mäntsälä, P, Hakala, J, Ylihonko, K

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Crystal structure of aclacinomycin-10-hydroxylase, a S-adenosyl-L-methionine-dependent methyltransferase homolog involved in anthracycline biosynthesis in Streptomyces purpurascens von Jansson, Anna, Niemi, Jarmo, Lindqvist, Ylva, Mäntsälä, Pekka, Schneider, Gunter

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An efficient approach for screening minimal PKS genes from Streptomyces von Metsä-Ketelä, Mikko, Salo, Virpi, Halo, Laura, Hautala, Anne, Hakala, Juha, Mäntsälä, Pekka, Ylihonko, Kristiina

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Crystal Structure of Bacillus subtilis YabJ, a Purine Regulatory Protein and Member of the Highly Conserved YjgF Family von Sinha, Sangita, Rappu, Pekka, Lange, S. C., Mäntsälä, Pekka, Zalkin, Howard, Smith, Janet L.

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A Role for a Highly Conserved Protein of Unknown Function in Regulation of Bacillus subtilis purA by the Purine Repressor von Rappu, P, Shin, B S, Zalkin, H, Mäntsälä, P

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Microbial amylolytic enzymes von VIHINEN, M, MÄNTSÄLÄ, P

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Identification of a Cyclase Gene Dictating the C-9 Stereochemistry of Anthracyclines from Streptomyces nogalater von Torkkell, S, Kunnari, T, Palmu, K, Hakala, J, Mäntsälä, P, Ylihonko, K

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Isolation and characterization of aclacinomycin A-non-producing Streptomyces galilaeus (ATCC 31615) mutants von Ylihonko, Kristiina, Hakala, Juha, Niemi, Jarmo, Lundell, Juhani, Mantsala, Pekka

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Crystal Structure of the Cofactor-Independent Monooxygenase SnoaB from Streptomyces nogalater: Implications for the Reaction Mechanism von Grocholski, Thadee, Koskiniemi, Hanna, Lindqvist, Ylva, Mäntsälä, Pekka, Niemi, Jarmo, Schneider, Gunter

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Structural basis for C-ribosylation in the alnumycin A biosynthetic pathway von Oja, Terhi, Niiranen, Laila, Sandalova, Tatyana, Klika, Karel D., Niemi, Jarmo, Mäntsälä, Pekka, Schneider, Gunter, Metsä-Ketelä, Mikko

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Opioid peptides derived from in-vitro proteolysis of bovine whey proteins von Antila, P., Paakkari, I., Järvinen, A., Mattila, M.J., Laukkanen, M., Pihlanto-Leppälä, A., Mäntsälä, P., Hellman, J.

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Crystallization and preliminary crystallographic data of SnoaL, a polyketide cyclase in nogalamycin biosynthesis von Sultana, Azmiri, Kallio, Pauli, Jansson, Anna, Niemi, Jarmo, Mäntsälä, Pekka, Schneider, Gunter

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Elucidation of anthracyclinone biosynthesis by stepwise cloning of genes for anthracyclines from three different Streptomyces spp von Kantola, Jaana, Kunnari, Tero, Hautala, Anne, Hakala, Juha, Ylihonko, Kristiina, Mantsala, Pekka

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