miR-625-3p regulates oxaliplatin resistance by directly targeting MAP2K6/MKK6 in human colorectal adenocarcinoma von Lyskjær, I, Rasmussen, M. Heilskov, Jersie-Christensen, R. Rakownikow, Tarpgaard, L. Schmidt, Nielsen, M. Muhlig, Pedersen, J. Skou, Ørntoft, T. Falck, Andersen, C. Lindbjerg

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1159P Individualized methylation-based dynamic analysis of cell-free DNA in postoperative monitoring of resected lung cancer von Chen, K., Kang, G., Zhang, Z., Lizaso, A., Beck, S., Lyskjær, I., Chervova, O., Li, B., Shen, H., Wang, C., Li, B., Zhao, H., Chuai, S., Yang, F., Kanu, N., Wang, J.

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584 - miR-625-3p regulates oxaliplatin resistance by directly targeting MAP2K6/MKK6 in human colorectal adenocarcinoma von Lyskjær, I., Rasmussen, M. Heilskov, Jersie-Christensen, R. Rakownikow, Tarpgaard, L. Schmidt, Nielsen, M. Muhlig, Pedersen, J. Skou, Ørntoft, T. Falck, Andersen, C. Lindbjerg

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H3K27me3 expression and methylation status in histological variants of malignant peripheral nerve sheath tumours von Lyskjær, I, Lindsay, D, Tirabosco, R, Steele, CD, Lombard, P, Strobl, A-C, Rocha, AM, Davies, C, Bekers, E, Ingruber, J, Lechner, M, Amary, F, Pillay, N, Flanagan, AM

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Drivers underpinning the malignant transformation of giant cell tumour of bone von Fittall, MW, Lyskjær, I, Ellery, P, Lombard, P, Ijaz, J, Strobl, A-C, Oukrif, D, Tarabichi, M, Sill, M, Koelsche, C, Mechtersheimer, G, Demeulemeester, J, Tirabosco, R, Amary, F, Campbell, PJ, Pfister, S, Jones, DTW, Pillay, N, Van Loo, P, Behjati, S, Flanagan, AM

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Sarcoma classification by DNA methylation profiling von Koelsche, C, Schrimpf, D, Stichel, D, Sill, M, Sahm, F, Reuss, DE, Blattner, M, Worst, B, Heilig, CE, Beck, K, Horak, P, Kreutzfeldt, S, Stark, S, Johann, P, Selt, F, Ecker, J, Pajtler, KW, Reinhardt, A, Sievers, P, Ebrahimi, A, Suwala, A, Fernández-Klett, F, Casalini, B, Hovestadt, V, Kommoss, FKF, Kriegsmann, M, Schick, M, Bewerunge-Hudler, M, Milde, T, Witt, O, Kool, M, Romero-Pérez, L, Grünewald, TGP, Kirchner, T, Wick, W, Platten, M, Uhl, M, Abdollahi, A, Debus, J, Lehner, B, Thomas, C, Hasselblatt, M, Hartmann, C, Staszewski, O, Prinz, M, Hench, J, Frank, S, Versleijen-Jonkers, YMH, Weidema, ME, Mentzel, T, Griewank, K, de Álava, E, Gastearena, MAI, Chang, KT-E, Low, SYY, Cuevas-Bourdier, A, Mittelbronn, M, Mynarek, M, Rutkowski, S, Schüller, U, Mautner, VF, Schittenhelm, J, Serrano, J, Snuderl, M, Büttner, R, Klingebiel, T, Buslei, R, Gessler, M, Wesseling, P, Dinjens, WNM, Jaunmuktane, Z, Lyskjær, I, Brors, B, Glimm, H, Heining, C, Tirado, OM, Sáinz-Jaspeado, M, Mora, J, Alonso, J, Del Muro, XG, Moran, S, Esteller, M, Benhamida, JK, Ladanyi, M, Wardelmann, E, Antonescu, C, Flanagan, A, Dirksen, U, Hohenberger, P, Baumhoer, D, Hartmann, W, Vokuhl, C, Flucke, U, Petersen, I, Mechtersheimer, G, Capper, D, Jones, DTW, Fröhling, S, Pfister, SM, von Deimling, A

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MYC amplifications are common events in childhood osteosarcoma von De Noon, S, Ijaz, J, Coorens, TH, Amary, F, Ye, H, Strobl, A, Lyskjaer, I, Flanagan, AM, Behjati, S

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DNA methylation-based profiling of bone and soft tissue tumours: a validation study of the 'DKFZ Sarcoma Classifier' von Lyskjaer, I, De Noon, S, Tirabosco, R, Rocha, AM, Lindsay, D, Amary, F, Ye, H, Schrimpf, D, Stichel, D, Sill, M, Koelsche, C, Pillay, N, Von Deimling, A, Beck, S, Flanagan, AM

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Circulating tumour DNA is a promising biomarker for risk stratification of central chondrosarcoma with IDH1/2 and GNAS mutations von Lyskjaer, I, Davies, C, Strobl, A-C, Hindley, J, James, S, Lalam, RK, Cross, W, Hide, G, Rankin, KS, Jeys, L, Tirabosco, R, Stevenson, J, Consortium, GER, O'Donnell, P, Cool, P, Flanagan, AM

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Editorial: Epigenetic biomarkers for cancer risk stratification and patient management von Tanić, Miljana, Ecker, Simone, Lyskjær, Iben

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Multicenter randomized trial of deferred cytoreductive nephrectomy in synchronous metastatic renal cell carcinoma receiving checkpoint inhibitors: the NORDIC-SUN-Trial von Iisager, Laura, Ahrenfeldt, Johanne, Donskov, Frede, Ljungberg, Börje, Bex, Axel, Lund, Lars, Lyskjær, Iben, Fristrup, Niels

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KIDNEY-PAGER: analysis of circulating tumor DNA as a biomarker in renal cancer - an observational trial. Study protocol von Iisager, Laura, Ahrenfeldt, Johanne, Keller, Anna Krarup, Nielsen, Tommy Kjærgaard, Fristrup, Niels, Lyskjær, Iben

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miR-625-3p regulates oxaliplatin resistance by targeting MAP2K6-p38 signalling in human colorectal adenocarcinoma cells von Rasmussen, Mads Heilskov, Lyskjær, Iben, Jersie-Christensen, Rosa Rakownikow, Tarpgaard, Line Schmidt, Primdal-Bengtson, Bjarke, Nielsen, Morten Muhlig, Pedersen, Jakob Skou, Hansen, Tine Plato, Hansen, Flemming, Olsen, Jesper Velgaard, Pfeiffer, Per, Ørntoft, Torben Falck, Andersen, Claus Lindbjerg

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DREAMS: deep read-level error model for sequencing data applied to low-frequency variant calling and circulating tumor DNA detection von Christensen, Mikkel H, Drue, Simon O, Rasmussen, Mads H, Frydendahl, Amanda, Lyskjær, Iben, Demuth, Christina, Nors, Jesper, Gotschalck, Kåre A, Iversen, Lene H, Andersen, Claus L, Pedersen, Jakob Skou

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Individualized dynamic methylation-based analysis of cell-free DNA in postoperative monitoring of lung cancer von Chen, Kezhong, Kang, Guannan, Zhang, Zhihong, Lizaso, Analyn, Beck, Stephan, Lyskjær, Iben, Chervova, Olga, Li, Bingsi, Shen, Haifeng, Wang, Chenyang, Li, Bing, Zhao, Heng, Li, Xi, Yang, Fan, Kanu, Nnennaya, Wang, Jun

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A genetic model for central chondrosarcoma evolution correlates with patient outcome von Cross, William, Lyskjær, Iben, Lesluyes, Tom, Hargreaves, Steven, Strobl, Anna-Christina, Davies, Christopher, Waise, Sara, Hames-Fathi, Shadi, Oukrif, Dahmane, Ye, Hongtao, Amary, Fernanda, Tirabosco, Roberto, Gerrand, Craig, Baker, Toby, Barnes, David, Steele, Christopher, Alexandrov, Ludmil, Bond, Gareth, Cool, Paul, Pillay, Nischalan, Van Loo, Peter, Flanagan, Adrienne M

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Epigenetic age acceleration is a distinctive trait of epithelioid sarcoma with potential therapeutic implications von Haefliger, Simon, Chervova, Olga, Davies, Christopher, Loh, Chet, Tirabosco, Roberto, Amary, Fernanda, Pillay, Nischalan, Horvath, Steve, Beck, Stephan, Flanagan, Adrienne M., Lyskjær, Iben

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DNA methylation‐based profiling of bone and soft tissue tumours: a validation study of the ‘DKFZ Sarcoma Classifier’ von Lyskjær, Iben, De Noon, Solange, Tirabosco, Roberto, Rocha, Ana Maia, Lindsay, Daniel, Amary, Fernanda, Ye, Hongtao, Schrimpf, Daniel, Stichel, Damian, Sill, Martin, Koelsche, Christian, Pillay, Nischalan, Von Deimling, Andreas, Beck, Stephan, Flanagan, Adrienne M

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Substitutions of Oatmeal and Breakfast Food Alternatives and the Rate of Stroke von Lyskjær, Line, Overvad, Kim, Tjønneland, Anne, Dahm, Christina C.

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Circulating tumour DNA is a promising biomarker for risk stratification of central chondrosarcoma with IDH1/2 and GNAS mutations von Lyskjær, Iben, Davies, Christopher, Strobl, Anna‐Christina, Hindley, Joanna, James, Steven, Lalam, Radhesh K., Cross, William, Hide, Geoff, Rankin, Kenneth S., Jeys, Lee, Tirabosco, Roberto, Stevenson, Jonathan, O’Donnell, Paul, Cool, Paul, Flanagan, Adrienne M.

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