An Alternative Pipeline for Glioblastoma Therapeutics: A Systematic Review of Drug Repurposing in Glioblastoma von Lyne, Sean B., Yamini, Bakhtiar

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Permissive microbiome characterizes human subjects with a neurovascular disease cavernous angioma von Polster, Sean P., Sharma, Anukriti, Tanes, Ceylan, Tang, Alan T., Mericko, Patricia, Cao, Ying, Carrión-Penagos, Julián, Girard, Romuald, Koskimäki, Janne, Zhang, Dongdong, Stadnik, Agnieszka, Romanos, Sharbel G., Lyne, Seán B., Shenkar, Robert, Yan, Kimberly, Lee, Cornelia, Akers, Amy, Morrison, Leslie, Robinson, Myranda, Zafar, Atif, Bittinger, Kyle, Kim, Helen, Gilbert, Jack A., Kahn, Mark L., Shen, Le, Awad, Issam A.

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Rho Kinase Inhibition Blunts Lesion Development and Hemorrhage in Murine Models of Aggressive Pdcd10/Ccm3 Disease von Shenkar, Robert, Peiper, Amy, Pardo, Heidy, Moore, Thomas, Lightle, Rhonda, Girard, Romuald, Hobson, Nicholas, Polster, Sean P, Koskimäki, Janne, Zhang, Dongdong, Lyne, Seán B, Cao, Ying, Chaudagar, Kiranj, Saadat, Laleh, Gallione, Carol, Pytel, Peter, Liao, James K, Marchuk, Douglas, Awad, Issam A

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Case Demonstrating the Nuances of Acute Cortical Venous Thrombosis Anticoagulation Guidelines von Polster, Sean P., Lyne, Seán B., Mansour, Ali

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Editorial for “Ensemble Learning for Early‐Response Prediction of Antidepressant Treatment in Major Depressive Disorder” von Srinath, Abhinav, Romanos, Sharbel, Lyne, Seán B., Leporq, Benjamin, Koskimäki, Janne, Girard, Romuald

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A comprehensive p75 neurotrophin receptor gene network and pathway analyses identifying new target genes von Sajanti, Antti, Lyne, Seán B., Girard, Romuald, Frantzén, Janek, Rantamäki, Tomi, Heino, Iiro, Cao, Ying, Diniz, Cassiano, Umemori, Juzoh, Li, Yan, Takala, Riikka, Posti, Jussi P., Roine, Susanna, Koskimäki, Fredrika, Rahi, Melissa, Rinne, Jaakko, Castrén, Eero, Koskimäki, Janne

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Towards a comprehensive understanding of p75 neurotrophin receptor functions and interactions in the brain von Ritala, Joel, Lyne, Seán, Sajanti, Antti, Girard, Romuald, Koskimäki, Janne

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Subclinical imaging changes in cerebral cavernous angiomas during prospective surveillance von Carrion-Penagos, Julian, Zeineddine, Hussein A., Polster, Sean P., Girard, Romuald, Lyne, Sean B., Koskimaki, Janne, Romanos, Sharbel, Srinath, Abhinav, Zhang, Dongdong, Cao, Ying, Stadnik, Agnieszka, Piedad, Kristina, Shenkar, Robert, Awad, Issam A.

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Brain plasticity and neuroinflammatory protein biomarkers with circulating MicroRNAs as predictors of acute brain injury outcome – A prospective cohort study von Sajanti, Antti, Li, Yan, Hellström, Santtu, Cao, Ying, Girard, Romuald, Umemori, Juzoh, Frantzén, Janek, Koskimäki, Fredrika, Lyne, Seán B., Falter, Johannes, Rantamäki, Tomi, Takala, Riikka, Posti, Jussi P., Roine, Susanna, Kolehmainen, Sulo, Srinath, Abhinav, Jänkälä, Miro, Puolitaival, Jukka, Rahi, Melissa, Rinne, Jaakko, Castrén, Eero, Koskimäki, Janne

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Perfusion and permeability as diagnostic biomarkers of cavernous angioma with symptomatic hemorrhage von Sone, Je Yeong, Li, Yan, Hobson, Nicholas, Romanos, Sharbel G, Srinath, Abhinav, Lyne, Seán B, Shkoukani, Abdallah, Carrión-Penagos, Julián, Stadnik, Agnieszka, Piedad, Kristina, Lightle, Rhonda, Moore, Thomas, Li, Ying, Bi, Dehua, Shenkar, Robert, Carroll, Timothy, Ji, Yuan, Girard, Romuald, Awad, Issam A

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Transcriptome clarifies mechanisms of lesion genesis versus progression in models of Ccm3 cerebral cavernous malformations von Koskimäki, Janne, Zhang, Dongdong, Li, Yan, Saadat, Laleh, Moore, Thomas, Lightle, Rhonda, Polster, Sean P, Carrión-Penagos, Julián, Lyne, Seán B, Zeineddine, Hussein A, Shi, Changbin, Shenkar, Robert, Romanos, Sharbel, Avner, Kenneth, Srinath, Abhinav, Shen, Le, Detter, Matthew R, Snellings, Daniel, Cao, Ying, Lopez-Ramirez, Miguel A, Fonseca, Gregory, Tang, Alan T, Faber, Pieter, Andrade, Jorge, Ginsberg, Mark, Kahn, Mark L, Marchuk, Douglas A, Girard, Romuald, Awad, Issam A

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Primary Sellar Paraganglioma: Case Report with Literature Review and Immunohistochemistry Resource von Lyne, Seán B., Polster, Sean P., Fidai, Shiraz, Pytel, Peter, Yamini, Bakhtiar

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Soluble Urokinase-Type Plasminogen Activator Receptor and Inflammatory Biomarker Response with Prognostic Significance after Acute Neuronal Injury - a Prospective Cohort Study von Sajanti, Antti, Hellström, Santtu, Bennett, Carolyn, Srinath, Abhinav, Jhaveri, Aditya, Cao, Ying, Takala, Riikka, Frantzén, Janek, Koskimäki, Fredrika, Falter, Johannes, Lyne, Seán B, Rantamäki, Tomi, Posti, Jussi P, Roine, Susanna, Jänkälä, Miro, Puolitaival, Jukka, Kolehmainen, Sulo, Girard, Romuald, Rahi, Melissa, Rinne, Jaakko, Castrén, Eero, Koskimäki, Janne

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In Vivo Manipulation of HIF-1α Expression During Glioma Genesis von Tiburcio, Patricia D. B., Lyne, Séan B., Eric Huang, L.

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Brain Plasticity Modulator p75 Neurotrophin Receptor in Human Urine after Different Acute Brain Injuries-A Prospective Cohort Study von Hellström, Santtu, Sajanti, Antti, Srinath, Abhinav, Bennett, Carolyn, Girard, Romuald, Cao, Ying, Frantzén, Janek, Koskimäki, Fredrika, Falter, Johannes, Lyne, Seán B, Rantamäki, Tomi, Takala, Riikka, Posti, Jussi P, Roine, Susanna, Puolitaival, Jukka, Jänkälä, Miro, Kolehmainen, Sulo, Rahi, Melissa, Rinne, Jaakko, Castrén, Eero, Koskimäki, Janne

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Outcome and survival of surgically treated acute subdural hematomas and postcraniotomy hematomas – A retrospective cohort study von Heino, Iiro, Sajanti, Antti, Lyne, Seán B., Frantzén, Janek, Girard, Romuald, Cao, Ying, Ritala, Joel F., Katila, Ari J., Takala, Riikka S.K., Posti, Jussi P., Saarinen, Antti J., Hellström, Santtu, Laukka, Dan, Saarenpää, Ilkka, Rahi, Melissa, Tenovuo, Olli, Rinne, Jaakko, Koskimäki, Janne

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Biomarkers of cavernous angioma with symptomatic hemorrhage von Lyne, Seán B, Girard, Romuald, Koskimäki, Janne, Zeineddine, Hussein A, Zhang, Dongdong, Cao, Ying, Li, Yan, Stadnik, Agnieszka, Moore, Thomas, Lightle, Rhonda, Shi, Changbin, Shenkar, Robert, Carrión-Penagos, Julián, Polster, Sean P, Romanos, Sharbel, Akers, Amy, Lopez-Ramirez, Miguel, Whitehead, Kevin J, Kahn, Mark L, Ginsberg, Mark H, Marchuk, Douglas A, Awad, Issam A

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Common transcriptome, plasma molecules, and imaging signatures in the aging brain and a Mendelian neurovascular disease, cerebral cavernous malformation von Koskimäki, Janne, Polster, Sean P., Li, Yan, Romanos, Sharbel, Srinath, Abhinav, Zhang, Dongdong, Carrión-Penagos, Julián, Lightle, Rhonda, Moore, Thomas, Lyne, Seán B., Stadnik, Agnieszka, Piedad, Kristina, Cao, Ying, Shenkar, Robert, Dimov, Alexey V., Hobson, Nick, Christoforidis, Gregory A., Carroll, Timothy, Girard, Romuald, Awad, Issam A.

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A multi-institutional phase I study of acetazolamide with temozolomide in adults with newly diagnosed MGMT-methylated malignant glioma von Driscoll, Riley K, Lyne, Sean B, Voce, David J, Maraka, Stefania, Gondi, Vinai, Chmura, Steven J, Dixit, Karan S, Kumthekar, Priya U, Karrison, Theodore G, Pytel, Peter, Collins, John M, Stupp, Roger, Merrell, Ryan T, Lukas, Rimas V, Yamini, Bakhtiar

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Abstract TP236: Temporal Metabolomic Profiling Exposed Affiliated Metabolites Altered And Associations To Outcome After Different Acute Brain Injuries von Hellström, Santtu, Sajanti, Antti, Girard, Romuald, Frantzen, Janek, Umemori, Juzoh, Koskimaki, Fredrika, Lyne, Sean B., Falter, Johannes, Rantamäki, Tomi, Nazir, Kenneth, Gajera, Bharat, Posti, Jussi, Roine, Susanna, Takala, Riikka, Kolehmainen, Sulo, Cao, Ying, Li, Yan, Heino, Iiro, Rahi, Melissa, Rinne, Jaakko, Nieminen, Anni, Castren, Eero, Koskimaki, Janne

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