Pioneer of prostate cancer: past, present and the future of FOXA1 von Teng, Mona, Zhou, Stanley, Cai, Changmeng, Lupien, Mathieu, Hansen He, Housheng

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GLUT1 inhibition blocks growth of RB1-positive triple negative breast cancer von Wu, Qin, ba-alawi, Wail, Deblois, Genevieve, Cruickshank, Jennifer, Duan, Shili, Lima-Fernandes, Evelyne, Haight, Jillian, Tonekaboni, Seyed Ali Madani, Fortier, Anne-Marie, Kuasne, Hellen, McKee, Trevor D., Mahmoud, Hassan, Kushida, Michelle, Cameron, Sarina, Dogan-Artun, Nergiz, Chen, WenJun, Nie, Yan, Zhang, Lan Xin, Vellanki, Ravi N., Zhou, Stanley, Prinos, Panagiotis, Wouters, Bradly G., Dirks, Peter B., Done, Susan J., Park, Morag, Cescon, David W., Haibe-Kains, Benjamin, Lupien, Mathieu, Arrowsmith, Cheryl H.

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A chemical toolbox for the study of bromodomains and epigenetic signaling von Wu, Qin, Heidenreich, David, Zhou, Stanley, Ackloo, Suzanne, Krämer, Andreas, Nakka, Kiran, Lima-Fernandes, Evelyne, Deblois, Genevieve, Duan, Shili, Vellanki, Ravi N., Li, Fengling, Vedadi, Masoud, Dilworth, Jeffrey, Lupien, Mathieu, Brennan, Paul E., Arrowsmith, Cheryl H., Müller, Susanne, Fedorov, Oleg, Filippakopoulos, Panagis, Knapp, Stefan

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PRMT5 inhibition disrupts splicing and stemness in glioblastoma von Sachamitr, Patty, Ho, Jolene C., Ciamponi, Felipe E., Ba-Alawi, Wail, Coutinho, Fiona J., Guilhamon, Paul, Kushida, Michelle M., Cavalli, Florence M. G., Lee, Lilian, Rastegar, Naghmeh, Vu, Victoria, Sánchez-Osuna, María, Coulombe-Huntington, Jasmin, Kanshin, Evgeny, Whetstone, Heather, Durand, Mathieu, Thibault, Philippe, Hart, Kirsten, Mangos, Maria, Veyhl, Joseph, Chen, Wenjun, Tran, Nhat, Duong, Bang-Chi, Aman, Ahmed M., Che, Xinghui, Lan, Xiaoyang, Whitley, Owen, Zaslaver, Olga, Barsyte-Lovejoy, Dalia, Richards, Laura M., Restall, Ian, Caudy, Amy, Röst, Hannes L., Bonday, Zahid Quyoom, Bernstein, Mark, Das, Sunit, Cusimano, Michael D., Spears, Julian, Bader, Gary D., Pugh, Trevor J., Tyers, Mike, Lupien, Mathieu, Haibe-Kains, Benjamin, Artee Luchman, H., Weiss, Samuel, Massirer, Katlin B., Prinos, Panagiotis, Arrowsmith, Cheryl H., Dirks, Peter B.

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Large organized chromatin lysine domains help distinguish primitive from differentiated cell populations von Madani Tonekaboni, Seyed Ali, Haibe-Kains, Benjamin, Lupien, Mathieu

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Pioneer factors: directing transcriptional regulators within the chromatin environment von Magnani, Luca, Eeckhoute, Jérôme, Lupien, Mathieu

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Genomic hallmarks of localized, non-indolent prostate cancer von Fraser, Michael, Sabelnykova, Veronica Y., Yamaguchi, Takafumi N., Heisler, Lawrence E., Livingstone, Julie, Huang, Vincent, Shiah, Yu-Jia, Yousif, Fouad, Lin, Xihui, Masella, Andre P., Fox, Natalie S., Xie, Michael, Prokopec, Stephenie D., Berlin, Alejandro, Lalonde, Emilie, Ahmed, Musaddeque, Trudel, Dominique, Luo, Xuemei, Beck, Timothy A., Meng, Alice, Zhang, Junyan, D’Costa, Alister, Denroche, Robert E., Kong, Haiying, Espiritu, Shadrielle Melijah G., Chua, Melvin L. K., Wong, Ada, Chong, Taryne, Sam, Michelle, Johns, Jeremy, Timms, Lee, Buchner, Nicholas B., Orain, Michèle, Picard, Valérie, Hovington, Helène, Murison, Alexander, Kron, Ken, Harding, Nicholas J., P’ng, Christine, Houlahan, Kathleen E., Chu, Kenneth C., Lo, Bryan, Nguyen, Francis, Li, Constance H., Sun, Ren X., de Borja, Richard, Cooper, Christopher I., Hopkins, Julia F., Govind, Shaylan K., Fung, Clement, Waggott, Daryl, Green, Jeffrey, Haider, Syed, Chan-Seng-Yue, Michelle A., Jung, Esther, Wang, Zhiyuan, Bergeron, Alain, Dal Pra, Alan, Lacombe, Louis, Collins, Colin C., Sahinalp, Cenk, Lupien, Mathieu, Fleshner, Neil E., He, Housheng H., Fradet, Yves, Tetu, Bernard, van der Kwast, Theodorus, McPherson, John D., Bristow, Robert G., Boutros, Paul C.

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Functional Enhancers Shape Extrachromosomal Oncogene Amplifications von Morton, Andrew R., Dogan-Artun, Nergiz, Faber, Zachary J., MacLeod, Graham, Bartels, Cynthia F., Piazza, Megan S., Allan, Kevin C., Mack, Stephen C., Wang, Xiuxing, Gimple, Ryan C., Wu, Qiulian, Rubin, Brian P., Shetty, Shashirekha, Angers, Stephane, Dirks, Peter B., Sallari, Richard C., Lupien, Mathieu, Rich, Jeremy N., Scacheri, Peter C.

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SMuRF: a novel tool to identify regulatory elements enriched for somatic point mutations von Guilhamon, Paul, Lupien, Mathieu

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Risk SNP-Mediated Promoter-Enhancer Switching Drives Prostate Cancer through lncRNA PCAT19 von Hua, Junjie Tony, Ahmed, Musaddeque, Guo, Haiyang, Zhang, Yuzhe, Chen, Sujun, Soares, Fraser, Lu, Jennifer, Zhou, Stanley, Wang, Miranda, Li, Hui, Larson, Nicholas B., McDonnell, Shannon K., Patel, Parasvi S., Liang, Yi, Yao, Cindy Q., van der Kwast, Theodorus, Lupien, Mathieu, Feng, Felix Y., Zoubeidi, Amina, Tsao, Ming-Sound, Thibodeau, Stephen N., Boutros, Paul C., He, Housheng Hansen

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Combinatorial effects of multiple enhancer variants in linkage disequilibrium dictate levels of gene expression to confer susceptibility to common traits von Corradin, Olivia, Saiakhova, Alina, Akhtar-Zaidi, Batool, Myeroff, Lois, Willis, Joseph, Cowper-Sal lari, Richard, Lupien, Mathieu, Markowitz, Sanford, Scacheri, Peter C

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Noncoding mutations target cis-regulatory elements of the FOXA1 plexus in prostate cancer von Zhou, Stanley, Hawley, James R., Soares, Fraser, Grillo, Giacomo, Teng, Mona, Madani Tonekaboni, Seyed Ali, Hua, Junjie Tony, Kron, Ken J., Mazrooei, Parisa, Ahmed, Musaddeque, Arlidge, Christopher, Yun, Hwa Young, Livingstone, Julie, Huang, Vincent, Yamaguchi, Takafumi N., Espiritu, Shadrielle M. G., Zhu, Yanyun, Severson, Tesa M., Murison, Alex, Cameron, Sarina, Zwart, Wilbert, van der Kwast, Theodorus, Pugh, Trevor J., Fraser, Michael, Boutros, Paul C., Bristow, Robert G., He, Housheng Hansen, Lupien, Mathieu

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TMPRSS2–ERG fusion co-opts master transcription factors and activates NOTCH signaling in primary prostate cancer von Kron, Ken J, Murison, Alexander, Zhou, Stanley, Huang, Vincent, Yamaguchi, Takafumi N, Shiah, Yu-Jia, Fraser, Michael, van der Kwast, Theodorus, Boutros, Paul C, Bristow, Robert G, Lupien, Mathieu

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The Proteogenomic Landscape of Curable Prostate Cancer von Sinha, Ankit, Huang, Vincent, Livingstone, Julie, Wang, Jenny, Fox, Natalie S., Kurganovs, Natalie, Ignatchenko, Vladimir, Fritsch, Katharina, Donmez, Nilgun, Heisler, Lawrence E., Shiah, Yu-Jia, Yao, Cindy Q., Alfaro, Javier A., Volik, Stas, Lapuk, Anna, Fraser, Michael, Kron, Ken, Murison, Alex, Lupien, Mathieu, Sahinalp, Cenk, Collins, Colin C., Tetu, Bernard, Masoomian, Mehdi, Berman, David M., van der Kwast, Theodorus, Bristow, Robert G., Kislinger, Thomas, Boutros, Paul C.

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PBX1 genomic pioneer function drives ERα signaling underlying progression in breast cancer von Magnani, Luca, Ballantyne, Elizabeth B, Zhang, Xiaoyang, Lupien, Mathieu

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Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy von Lan, Xiaoyang, Jörg, David J., Cavalli, Florence M. G., Richards, Laura M., Nguyen, Long V., Vanner, Robert J., Guilhamon, Paul, Lee, Lilian, Kushida, Michelle M., Pellacani, Davide, Park, Nicole I., Coutinho, Fiona J., Whetstone, Heather, Selvadurai, Hayden J., Che, Clare, Luu, Betty, Carles, Annaick, Moksa, Michelle, Rastegar, Naghmeh, Head, Renee, Dolma, Sonam, Prinos, Panagiotis, Cusimano, Michael D., Das, Sunit, Bernstein, Mark, Arrowsmith, Cheryl H., Mungall, Andrew J., Moore, Richard A., Ma, Yussanne, Gallo, Marco, Lupien, Mathieu, Pugh, Trevor J., Taylor, Michael D., Hirst, Martin, Eaves, Connie J., Simons, Benjamin D., Dirks, Peter B.

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Biological and therapeutic implications of a unique subtype of NPM1 mutated AML von Mer, Arvind Singh, Heath, Emily M., Madani Tonekaboni, Seyed Ali, Dogan-Artun, Nergiz, Nair, Sisira Kadambat, Murison, Alex, Garcia-Prat, Laura, Shlush, Liran, Hurren, Rose, Voisin, Veronique, Bader, Gary D., Nislow, Corey, Rantalainen, Mattias, Lehmann, Soren, Gower, Mark, Guidos, Cynthia J., Lupien, Mathieu, Dick, John E., Minden, Mark D., Schimmer, Aaron D., Haibe-Kains, Benjamin

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Single-cell chromatin accessibility profiling of glioblastoma identifies an invasive cancer stem cell population associated with lower survival von Guilhamon, Paul, Chesnelong, Charles, Kushida, Michelle M., Nikolic, Ana, Singhal, Divya, MacLeod, Graham, Tonekaboni, Seyed Ali Madani, Cavalli, Florence M. G., Arlidge, Christopher, Rajakulendran, Nishani, Rastegar, Naghmeh, Hao, Xiaoguang, Hassam, Rozina, Smith, Laura J., Whetstone, Heather, Coutinho, Fiona J., Nadorp, Bettina, Ellestad, Katrina, Luchman, H. Artee, Chan, Jennifer Ai-wen, Shoichet, Molly S., Taylor, Michael D., Haibe-Kains, Benjamin, Weiss, Samuel, Angers, Stephane, Gallo, Marco, Dirks, Peter B., Lupien, Mathieu

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Human papillomavirus integration transforms chromatin to drive oncogenesis von Karimzadeh, Mehran, Arlidge, Christopher, Rostami, Ariana, Lupien, Mathieu, Bratman, Scott V, Hoffman, Michael M

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Breast cancer risk–associated SNPs modulate the affinity of chromatin for FOXA1 and alter gene expression von Cowper-Sal·lari, Richard, Zhang, Xiaoyang, Wright, Jason B, Bailey, Swneke D, Cole, Michael D, Eeckhoute, Jerome, Moore, Jason H, Lupien, Mathieu

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