Prospective DPYD genotyping to reduce the risk of fluoropyrimidine-induced severe toxicity: Ready for prime time von Lunenburg, Carin A.T.C, Henricks, Linda M, Guchelaar, Henk-Jan, Swen, Jesse J, Deenen, Maarten J, Schellens, Jan H.M, Gelderblom, Hans

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Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene-drug interaction of DPYD and fluoropyrimidines von Lunenburg, Carin A T C, van der Wouden, Cathelijne H, Nijenhuis, Marga, Crommentuijn-van Rhenen, Mandy H, de Boer-Veger, Nienke J, Buunk, Anne Marie, Houwink, Elisa J F, Mulder, Hans, Rongen, Gerard A, van Schaik, Ron H N, van der Weide, Jan, Wilffert, Bob, Deneer, Vera H M, Swen, Jesse J, Guchelaar, Henk-Jan

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Pharmacogenetics in psychiatric care, a call for uptake of available applications von Lunenburg, Carin A.T.C., Gasse, Christiane

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Translating DPYD genotype into DPD phenotype: using the DPYD gene activity score von Henricks, Linda M, Lunenburg, Carin A T C, Meulendijks, Didier, Gelderblom, Hans, Cats, Annemieke, Swen, Jesse J, Schellens, Jan H M, Guchelaar, Henk-Jan

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Clinical Impact of Functional CYP2C19 and CYP2D6 Gene Variants on Treatment with Antidepressants in Young People with Depression: A Danish Cohort Study von Thiele, Liv S, Ishtiak-Ahmed, Kazi, Thirstrup, Janne P, Agerbo, Esben, Lunenburg, Carin A T C, Müller, Daniel J, Gasse, Christiane

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Survival of Patients With Cancer With DPYD Variant Alleles and Dose-Individualized Fluoropyrimidine Therapy-A Matched-Pair Analysis von Knikman, Jonathan E, Wilting, Tycho A, Lopez-Yurda, Marta, Henricks, Linda M, Lunenburg, Carin A T C, de Man, Femke M, Meulendijks, Didier, Nieboer, Peter, Droogendijk, Helga J, Creemers, Geert-Jan, Mandigers, Caroline M P W, Imholz, Alexander L T, Mathijssen, Ron H J, Portielje, Johanneke E A, Valkenburg-van Iersel, Liselot, Vulink, Annelie, van der Poel, Marlene H W, Baars, Arnold, Swen, Jesse J, Gelderblom, Hans, Schellens, Jan H M, Beijnen, Jos H, Guchelaar, Henk-Jan, Cats, Annemieke

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Dihydropyrimidine Dehydrogenase Phenotyping Using Pretreatment Uracil: A Note of Caution Based on a Large Prospective Clinical Study von With, Mirjam, Knikman, Jonathan, Man, Femke M., Lunenburg, Carin A. T. C., Henricks, Linda M., Kuilenburg, André B. P., Maring, Jan G., Staveren, Maurice C., Vries, Niels, Rosing, Hilde, Beijnen, Jos H., Pluim, Dick, Modak, Anil, Imholz, Alex L. T., Schaik, Ron H. N., Schellens, Jan H. M., Gelderblom, Hans, Cats, Annemieke, Guchelaar, Henk‐Jan, Mathijssen, Ron H. J., Swen, Jesse J., Meulendijks, Didier

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Pharmacogenetic genotype and phenotype frequencies in a large Danish population-based case-cohort sample von Lunenburg, Carin A. T. C., Thirstrup, Janne P., Bybjerg-Grauholm, Jonas, Bækvad-Hansen, Marie, Hougaard, David M., Nordentoft, Merete, Werge, Thomas, Børglum, Anders D., Mors, Ole, Mortensen, Preben B., Gasse, Christiane

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Standard fluoropyrimidine dosages in chemoradiation therapy result in an increased risk of severe toxicity in DPYD variant allele carriers von Lunenburg, Carin A.T.C., Henricks, Linda M., Dreussi, Eva, Peters, Femke P., Fiocco, Marta, Meulendijks, Didier, Toffoli, Giuseppe, Guchelaar, Henk-Jan, Swen, Jesse J., Cecchin, Erika, Schellens, Jan H.M., Gelderblom, Hans

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Evaluation of clinical implementation of prospective DPYD genotyping in 5-fluorouracil- or capecitabine-treated patients von Lunenburg, Carin Atc, van Staveren, Maurice C, Gelderblom, Hans, Guchelaar, Henk-Jan, Swen, Jesse J

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Confirmation practice in pharmacogenetic testing; how good is good enough? von Lunenburg, Carin A.T.C., Guchelaar, Henk-Jan, van Schaik, Ron H.N., Neumaier, Michael, Swen, Jesse J.

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A cost analysis of upfront DPYD genotype–guided dose individualisation in fluoropyrimidine-based anticancer therapy von Henricks, Linda M., Lunenburg, Carin A.T.C., de Man, Femke M., Meulendijks, Didier, Frederix, Geert W.J., Kienhuis, Emma, Creemers, Geert-Jan, Baars, Arnold, Dezentjé, Vincent O., Imholz, Alexander L.T., Jeurissen, Frank J.F., Portielje, Johanna E.A., Jansen, Rob L.H., Hamberg, Paul, ten Tije, Albert J., Droogendijk, Helga J., Koopman, Miriam, Nieboer, Peter, van de Poel, Marlène H.W., Mandigers, Caroline M.P.W., Rosing, Hilde, Beijnen, Jos H., van Werkhoven, Erik, van Kuilenburg, André B.P., van Schaik, Ron H.N., Mathijssen, Ron H.J., Swen, Jesse J., Gelderblom, Hans, Cats, Annemieke, Guchelaar, Henk-Jan, Schellens, Jan H.M.

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DPYD genotype-guided dose individualisation of fluoropyrimidine therapy: who and how? – Authors' reply von Henricks, Linda M, Lunenburg, Carin A T C, Cats, Annemieke, Mathijssen, Ron H J, Guchelaar, Henk-Jan, Schellens, Jan H M

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Diagnostic and Therapeutic Strategies for Fluoropyrimidine Treatment of Patients Carrying Multiple DPYD Variants von Lunenburg, Carin A T C, Henricks, Linda M, van Kuilenburg, André B P, Mathijssen, Ron H J, Schellens, Jan H M, Gelderblom, Hans, Guchelaar, Henk-Jan, Swen, Jesse J

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Discovering novel germline genetic variants linked to severe fluoropyrimidine-related toxicity in- and outside DPYD von Knikman, Jonathan E, Zhai, Qinglian, Lunenburg, Carin A T C, Henricks, Linda M, Böhringer, Stefan, van der Lee, Maaike, de Man, Femke M, Offer, Steven M, Shrestha, Shikshya, Creemers, Geert-Jan, Baars, Arnold, Dezentjé, Vincent O, Imholz, Alexander L T, Jeurissen, Frank J F, Portielje, Johanna E A, Jansen, Rob L H, Hamberg, Paul, Droogendijk, Helga J, Koopman, Miriam, Nieboer, Peter, van de Poel, Marlène H W, Mandigers, Caroline M P W, van Schaik, Ron H N, Gelderblom, Hans, Mathijssen, Ron H J, Schellens, Jan H M, Cats, Annemieke, Guchelaar, Henk-Jan, Swen, Jesse J

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Primary Care Prescription Drug Use and Related Actionable Drug‐Gene Interactions in the Danish Population von Lunenburg, Carin Adriana Theodora Catharina, Hauser, Alexander Sebastian, Ishtiak‐Ahmed, Kazi, Gasse, Christiane

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DPYD genotype-guided dose individualisation of fluoropyrimidine therapy in patients with cancer: a prospective safety analysis von Henricks, Linda M, Lunenburg, Carin A T C, de Man, Femke M, Meulendijks, Didier, Frederix, Geert W J, Kienhuis, Emma, Creemers, Geert-Jan, Baars, Arnold, Dezentjé, Vincent O, Imholz, Alexander L T, Jeurissen, Frank J F, Portielje, Johanna E A, Jansen, Rob L H, Hamberg, Paul, ten Tije, Albert J, Droogendijk, Helga J, Koopman, Miriam, Nieboer, Peter, van de Poel, Marlène H W, Mandigers, Caroline M P W, Rosing, Hilde, Beijnen, Jos H, Werkhoven, Erik van, van Kuilenburg, André B P, van Schaik, Ron H N, Mathijssen, Ron H J, Swen, Jesse J, Gelderblom, Hans, Cats, Annemieke, Guchelaar, Henk-Jan, Schellens, Jan H M

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CLINICAL IMPACT OF FUNCTIONAL CYP2C19 AND CYP2D6 GENE VARIANTS ON TREATMENT WITH ANTIDEPRESSANTS IN PATIENTS WITH DEPRESSION: A DANISH COHORT STUDY von Thiele, Liv Swea, Ishtiak-Ahmed, Kazi, Thirstrup, Janne Pia, Agerbo, Esben, Lunenburg, Carin, Müller, Daniel J., Gasse, Christiane

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DPYD genotype-guided dose individualisation of fluoropyrimidine therapy: who and how? - Authors' reply von Henricks, Linda M, Lunenburg, Carin A T C, Cats, Annemieke, Mathijssen, Ron H J, Guchelaar, Henk-Jan, Schellens, Jan H M

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Discovering novel germline genetic variants linked to severe fluoropyrimidine-related toxicity in- and outside DPYD von Knikman, Jonathan E, Zhai, Qinglian, Lunenburg, Carin A.T.C, Henricks, Linda M, Böhringer, Stefan, van der Lee, Maaike, de Man, Femke M, Offer, Steven M, Shrestha, Shikshya, Creemers, Geert Jan, Baars, Arnold, Dezentjé, Vincent O, Imholz, Alexander L.T, Jeurissen, Frank J.F, Portielje, Johanna E.A, Jansen, Rob L.H, Hamberg, Paul, Droogendijk, Helga J, Koopman, Miriam, Nieboer, Peter, van de Poel, Marlène H.W, Mandigers, Caroline M.P.W, van Schaik, Ron H.N, Gelderblom, Hans, Mathijssen, Ron H.J, Schellens, Jan H.M, Cats, Annemieke, Guchelaar, Henk Jan, Swen, Jesse J

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