Oligonucleotide⁻Palladacycle Conjugates as Splice-Correcting Agents von Hande, Madhuri, Saher, Osama, Lundin, Karin E, Smith, C I Edvard, Zain, Rula, Lönnberg, Tuomas

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The ability of locked nucleic acid oligonucleotides to pre-structure the double helix: A molecular simulation and binding study von Xu, You, Gissberg, Olof, Pabon-Martinez, Y Vladimir, Wengel, Jesper, Lundin, Karin E, Smith, C I Edvard, Zain, Rula, Nilsson, Lennart, Villa, Alessandra

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LNA effects on DNA binding and conformation: from single strand to duplex and triplex structures von Pabon-Martinez, Y. Vladimir, Xu, You, Villa, Alessandra, Lundin, Karin E., Geny, Sylvain, Nguyen, Chi-Hung, Pedersen, Erik B., Jørgensen, Per T., Wengel, Jesper, Nilsson, Lennart, Smith, C. I. Edvard, Zain, Rula

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CTG repeat-targeting oligonucleotides for down-regulating Huntingtin expression von Zaghloul, Eman M, Gissberg, Olof, Moreno, Pedro M D, Siggens, Lee, Hällbrink, Mattias, Jørgensen, Anna S, Ekwall, Karl, Zain, Rula, Wengel, Jesper, Lundin, Karin E, Smith, C I Edvard

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Oligonucleotide Binding to Non-B-DNA in MYC von Umek, Tea, Sollander, Karin, Bergquist, Helen, Wengel, Jesper, Lundin, Karin E, Smith, C I Edvard, Zain, Rula

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Oligonucleotide Therapies: The Past and the Present von Lundin, Karin E, Gissberg, Olof, Smith, C I Edvard

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Eleven percent intact PGM3 in a severely immunodeficient patient with a novel splice-site mutation, a case report von Lundin, Karin E, Wang, Qing, Hamasy, Abdulrahman, Marits, Per, Uzunel, Mehmet, Wirta, Valtteri, Wikström, Ann-Charlotte, Fasth, Anders, Ekwall, Olov, Smith, C I Edvard

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RNA therapeutics inactivate PCSK9 by inducing a unique intracellular retention form von Rocha, Cristina S.J, Wiklander, Oscar P.B, Larsson, Lilian, Moreno, Pedro M.D, Parini, Paolo, Lundin, Karin E, Smith, C.I. Edvard

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Lipophilic Peptide Dendrimers for Delivery of Splice-Switching Oligonucleotides von Daralnakhla, Haneen, Saher, Osama, Zamolo, Susanna, Bazaz, Safa, P. Bost, Jeremy, Heitz, Marc, Lundin, Karin E., El Andaloussi, Samir, Darbre, Tamis, Reymond, Jean-Louis, Zain, Rula, Smith, C. I. Edvard

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Four Novel Splice-Switch Reporter Cell Lines: Distinct Impact of Oligonucleotide Chemistry and Delivery Vector on Biological Activity von Rocha, Cristina S.J., Lundin, Karin E., Behlke, Mark A., Zain, Rula, EL Andaloussi, Samir, Smith, C.I. Edvard

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Hypomorphic homozygous mutations in phosphoglucomutase 3 ( PGM3 ) impair immunity and increase serum IgE levels von Sassi, Atfa, PhD, Lazaroski, Sandra, PhD, Wu, Gang, MSc, Haslam, Stuart M., PhD, Fliegauf, Manfred, PhD, Mellouli, Fethi, MD, Patiroglu, Turkan, MD, Unal, Ekrem, MD, Ozdemir, Mehmet Akif, MD, Jouhadi, Zineb, MD, Khadir, Khadija, MD, Ben-Khemis, Leila, MSc, Ben-Ali, Meriem, PhD, Ben-Mustapha, Imen, MD, Borchani, Lamia, PhD, Pfeifer, Dietmar, PhD, Jakob, Thilo, MD, Khemiri, Monia, MD, Asplund, A. Charlotta, BSc, Gustafsson, Manuela O., MSc, Lundin, Karin E., PhD, Falk-Sörqvist, Elin, MSc, Moens, Lotte N., PhD, Gungor, Hatice Eke, MD, Engelhardt, Karin R., PhD, Dziadzio, Magdalena, MD, PhD, Stauss, Hans, MD, PhD, Fleckenstein, Bernhard, MD, Meier, Rebecca, BSc, Prayitno, Khairunnadiya, MSc, Maul-Pavicic, Andrea, PhD, Schaffer, Sandra, Rakhmanov, Mirzokhid, PhD, Henneke, Philipp, MD, Kraus, Helene, MSc, Eibel, Hermann, PhD, Kölsch, Uwe, MD, Nadifi, Sellama, PhD, Nilsson, Mats, PhD, Bejaoui, Mohamed, MD, Schäffer, Alejandro A., PhD, Smith, C.I. Edvard, MD, PhD, Dell, Anne, PhD, Barbouche, Mohamed-Ridha, MD, PhD, Grimbacher, Bodo, MD

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Micro-minicircle Gene Therapy: Implications of Size on Fermentation, Complexation, Shearing Resistance, and Expression von Stenler, Sofia, Wiklander, Oscar PB, Badal-Tejedor, Maria, Turunen, Janne, Nordin, Joel Z, Hallengärd, David, Wahren, Britta, Andaloussi, Samir EL, Rutland, Mark W, Smith, CI Edvard, Lundin, Karin E, Blomberg, Pontus

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Chemical Development of Therapeutic Oligonucleotides von Lundin, Karin E., Gissberg, Olof, Smith, C. I. Edvard, Zain, Rula

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Role of Pseudoisocytidine Tautomerization in Triplex-Forming Oligonucleotides: In Silico and in Vitro Studies von Hartono, Yossa Dwi, Pabon-Martinez, Y. Vladimir, Uyar, Arzu, Wengel, Jesper, Lundin, Karin E, Zain, Rula, Smith, C. I. Edvard, Nilsson, Lennart, Villa, Alessandra

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Novel peptide-dendrimer/lipid/oligonucleotide ternary complexes for efficient cellular uptake and improved splice-switching activity von Saher, Osama, Rocha, Cristina S.J., Zaghloul, Eman M., Wiklander, Oscar P.B., Zamolo, Susanna, Heitz, Marc, Ezzat, Kariem, Gupta, Dhanu, Reymond, Jean-Louis, Zain, Rula, Hollfelder, Florian, Darbre, Tamis, Lundin, Karin E., EL Andaloussi, Samir, Smith, C.I. Edvard

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Oligonucleotide-Based Therapies: Methods and Protocols von Gissberg, Olof, Zain, Rula, Lundin, Karin E

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2′-O-(N-(Aminoethyl)carbamoyl)methyl Modification Allows for Lower Phosphorothioate Content in Splice-Switching Oligonucleotides with Retained Activity von Honcharenko, Dmytro, Rocha, Cristina S J, Lundin, Karin E, Maity, Jyotirmoy, Milton, Stefan, Tedebark, Ulf, Murtola, Merita, Honcharenko, Malgorzata, Slaitas, Andis, Smith, C I Edvard, Zain, Rula, Strömberg, Roger

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Zorro locked nucleic acid induces sequence-specific gene silencing von Ge, Rongbin, Heinonen, Juhana E, Svahn, Mathias G, Mohamed, Abdalla J, Lundin, Karin E, Smith, C.I. Edvard

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Oligonucleotides Targeting DNA Repeats Downregulate Huntingtin Gene Expression in Huntington's Patient-Derived Neural Model System von Umek, Tea, Olsson, Thomas, Gissberg, Olof, Saher, Osama, Zaghloul, Eman M., Lundin, Karin E., Wengel, Jesper, Hanse, Eric, Zetterberg, Henrik, Vizlin-Hodzic, Dzeneta, Smith, C. I. Edvard, Zain, Rula

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Chemical Modifications and Design Influence the Potency of Huntingtin Anti-Gene Oligonucleotides von Saher, Osama, Zaghloul, Eman M, Umek, Tea, Hagey, Daniel W, Mozafari, Negin, Danielsen, Mathias B, Gouda, Alaa S, Lundin, Karin E, Jørgensen, Per T, Wengel, Jesper, Smith, C I Edvard, Zain, Rula

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