Abstract 571: MYBPC3 Mutations Cause Hypertrophic Cardiomyopathy by Dysregulating Myosin: Implications for Therapy von Toepfer, Christopher N, Wakimoto, Hiroko, Garfinkel, Amanda C, McDonough, Barbara, Liao, Dan, Jiang, Jianming, Tai, Angela, Gorham, Josh, Lund, Ida G, Lun, Mingyue, Lynch, Thomas L, Sadayappan, Sakthivel, Redwood, Charles S, Watkins, Hugh, Seidman, Jonathan, Seidman, Christine

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Comorbidities and cause-specific outcomes in heart failure across the ejection fraction spectrum: A blueprint for clinical trial design von Savarese, Gianluigi, Settergren, Camilla, Schrage, Benedikt, Thorvaldsen, Tonje, Löfman, Ida, Sartipy, Ulrik, Mellbin, Linda, Meyers, Andrea, Farsani, Soulmaz Fazeli, Brueckmann, Martina, Brodovicz, Kimberly G., Vedin, Ola, Asselbergs, Folkert W., Dahlström, Ulf, Cosentino, Francesco, Lund, Lars H.

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Novel drug resistance mechanisms and drug targets in BRAF-mutated peritoneal metastasis from colorectal cancer von Lund-Andersen, Christin, Torgunrud, Annette, Kanduri, Chakravarthi, Dagenborg, Vegar J, Frøysnes, Ida S, Larsen, Mette M, Davidson, Ben, Larsen, Stein G, Flatmark, Kjersti

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Urokinase‐type plasminogen activator contributes to amiloride‐sensitive sodium retention in nephrotic range glomerular proteinuria in mice von Hinrichs, Gitte R., Weyer, Kathrin, Friis, Ulla G., Svenningsen, Per, Lund, Ida K., Nielsen, Rikke, Mollet, Géraldine, Antignac, Corinne, Bistrup, Claus, Jensen, Boye L., Birn, Henrik

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A factor VIIIa–mimetic bispecific antibody, Mim8, ameliorates bleeding upon severe vascular challenge in hemophilia A mice von Østergaard, Henrik, Lund, Jacob, Greisen, Per J., Kjellev, Stine, Henriksen, Anette, Lorenzen, Nikolai, Johansson, Eva, Røder, Gustav, Rasch, Morten G., Johnsen, Laust B., Egebjerg, Thomas, Lund, Søren, Rahbek-Nielsen, Henrik, Gandhi, Prafull S., Lamberth, Kasper, Loftager, Mette, Andersen, Lisbeth M., Bonde, Amalie C., Stavenuiter, Fabian, Madsen, Daniel E., Li, Xun, Holm, Thomas L., Ley, Carsten D., Thygesen, Peter, Zhu, Haisun, Zhou, Rong, Thorn, Karina, Yang, Zhiru, Hermit, Mette B., Bjelke, Jais R., Hansen, Bjarne G., Hilden, Ida

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Virus-induced gene silencing as a tool for functional genomics in a legume species von Constantin, G.D, Krath, B.N, MacFarlane, S.A, Nicolaisen, M, Johansen, I.E, Lund, O.S

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Atrial disease and heart failure: the common soil hypothesis proposed by the Heart Failure Association of the European Society of Cardiology von Coats, Andrew J S, Heymans, Stephane, Farmakis, Dimitrios, Anker, Stefan D, Backs, Johannes, Bauersachs, Johann, de Boer, Rudolf A, Čelutkienė, Jelena, Cleland, John G F, Dobrev, Dobromir, van Gelder, Isabelle C, von Haehling, Stephan, Hindricks, Gerhard, Jankowska, Ewa, Kotecha, Dipak, van Laake, Linda W, Lainscak, Mitja, Lund, Lars H, Lunde, Ida Gjervold, Lyon, Alexander R, Manouras, Aristomenis, Miličić, Davor, Mueller, Christian, Polovina, Marija, Ponikowski, Piotr, Rosano, Giuseppe, Seferović, Petar M, Tschöpe, Carsten, Wachter, Rolf, Ruschitzka, Frank

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Rates and predictors of cardiovascular and non‐cardiovascular outcomes in heart failure with preserved ejection fraction von Shahim, Angiza, Donal, Erwan, Hage, Camilla, Oger, Emmanuel, Savarese, Gianluigi, Persson, Hans, Haugen‐Löfman, Ida, Ennezat, Pierre‐Vladimir, Sportouch‐Dukhan, Catherine, Drouet, Elodie, Daubert, Jean‐Claude, Linde, Cecilia, Lund, Lars H.

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Plasminogen Deficiency and Amiloride Mitigate Angiotensin II-Induced Hypertension in Type 1 Diabetic Mice Suggesting Effects Through the Epithelial Sodium Channel von Andersen, Henrik, Hansen, Maria Høj, Buhl, Kristian B, Stæhr, Mette, Friis, Ulla G, Enggaard, Camilla, Supramaniyam, Shanya, Lund, Ida K, Svenningsen, Per, Hansen, Pernille B L, Jensen, Boye L

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Gluco-metabolic response to exogenous oxytocin in totally pancreatectomized patients and healthy individuals von Kliim-Hansen, Vivian, Gether, Ida M., Juel, Caroline T.-B., Ellegaard, Anne-Marie, Pedersen, Miriam G., Hartmann, Bolette, Wewer Albrechtsen, Nicolai J., Holst, Jens J., Lund, Asger B., Gasbjerg, Lærke S., Knop, Filip K.

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Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes von Nielsen, H Bjørn, Almeida, Mathieu, Juncker, Agnieszka Sierakowska, Rasmussen, Simon, Li, Junhua, Sunagawa, Shinichi, Plichta, Damian R, Gautier, Laurent, Pedersen, Anders G, Le Chatelier, Emmanuelle, Pelletier, Eric, Bonde, Ida, Nielsen, Trine, Manichanh, Chaysavanh, Arumugam, Manimozhiyan, Batto, Jean-Michel, Quintanilha dos Santos, Marcelo B, Blom, Nikolaj, Borruel, Natalia, Burgdorf, Kristoffer S, Boumezbeur, Fouad, Casellas, Francesc, Doré, Joël, Dworzynski, Piotr, Guarner, Francisco, Hansen, Torben, Hildebrand, Falk, Kaas, Rolf S, Kennedy, Sean, Kristiansen, Karsten, Kultima, Jens Roat, Léonard, Pierre, Levenez, Florence, Lund, Ole, Moumen, Bouziane, Le Paslier, Denis, Pons, Nicolas, Pedersen, Oluf, Prifti, Edi, Qin, Junjie, Raes, Jeroen, Sørensen, Søren, Tap, Julien, Tims, Sebastian, Ussery, David W, Yamada, Takuji, Renault, Pierre, Sicheritz-Ponten, Thomas, Bork, Peer, Wang, Jun, Brunak, Søren, Ehrlich, S Dusko

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Antibody-mediated Targeting of the Urokinase-type Plasminogen Activator Proteolytic Function Neutralizes Fibrinolysis in Vivo von Lund, Ida K., Jögi, Annika, Rønø, Birgitte, Rasch, Morten G., Lund, Leif R., Almholt, Kasper, Gårdsvoll, Henrik, Behrendt, Niels, Rømer, John, Høyer-Hansen, Gunilla

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Bone Marrow-derived Myofibroblasts Are the Providers of Pro-invasive Matrix Metalloproteinase 13 in Primary Tumor von Lecomte, Julie, Masset, Anne, Blacher, Silvia, Maertens, Ludovic, Gothot, André, Delgaudine, Marie, Bruyère, Françoise, Carnet, Oriane, Paupert, Jenny, Illemann, Martin, Foidart, Jean-Michel, Lund, Ida K, Høyer-Hansen, Gunilla, Noel, Agnes

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New and paradoxical roles of matrix metalloproteinases in the tumor microenvironment von Noël, Agnès, Gutiérrez-Fernández, Ana, Sounni, Nor Eddine, Behrendt, Niels, Maquoi, Erik, Lund, Ida K, Cal, Santiago, Hoyer-Hansen, Gunilla, López-Otín, Carlos

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Genetic control of variability in subcortical and intracranial volumes von Córdova-Palomera, Aldo, van der Meer, Dennis, Kaufmann, Tobias, Bettella, Francesco, Wang, Yunpeng, Alnæs, Dag, Doan, Nhat Trung, Agartz, Ingrid, Bertolino, Alessandro, Buitelaar, Jan K., Coynel, David, Djurovic, Srdjan, Dørum, Erlend S., Espeseth, Thomas, Fazio, Leonardo, Franke, Barbara, Frei, Oleksandr, Håberg, Asta, Le Hellard, Stephanie, Jönsson, Erik G., Kolskår, Knut K., Lund, Martina J., Moberget, Torgeir, Nordvik, Jan E., Nyberg, Lars, Papassotiropoulos, Andreas, Pergola, Giulio, de Quervain, Dominique, Rampino, Antonio, Richard, Genevieve, Rokicki, Jaroslav, Sanders, Anne-Marthe, Schwarz, Emanuel, Smeland, Olav B., Steen, Vidar M., Starrfelt, Jostein, Sønderby, Ida E., Ulrichsen, Kristine M., Andreassen, Ole A., Westlye, Lars T.

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Diet of the European bison (Bison bonasus) in a forest habitat estimated by DNA barcoding von Hartvig, Ida, Howe, Andy G., Schmidt, Emilie N. B., Pertoldi, Cino, Nielsen, Jeppe Lund, Buttenschøn, Rita M.

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Generation of minipigs with targeted transgene insertion by recombinase-mediated cassette exchange (RMCE) and somatic cell nuclear transfer (SCNT) von Jakobsen, Jannik Ejnar, Johansen, Marianne G., Schmidt, Mette, Dagnæs-Hansen, Frederik, Dam, Karen, Gunnarsson, Anders, Liu, Ying, Kragh, Peter M., Li, Rong, Holm, Ida E., Callesen, Henrik, Mikkelsen, Jacob Giehm, Nielsen, Anders Lade, Jørgensen, Arne Lund

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Mim8 - a Next-Generation FVIII Mimetic Bi-Specific Antibody - Potently Restores the Hemostatic Capacity in Hemophilia a Settings in Vitro and In Vivo von Kjellev, Stine L, Østergaard, Henrik, Greisen, Per Jr, Hermit, Mette B, Thorn, Karina, Hansen, Bjarne G, Zhou, Rong, Bjelke, Jais Rose, Kjalke, Marianne, Lund, Jacob, Holm, Thomas L, Ley, Carsten Dan, Elenius, Daniel, Thygesen, Peter, Loftager, Mette, Rasch, Morten G, Lorenzen, Nikolai, Gandhi, Prafull S, Lamberth, Kasper, Egebjerg, Thomas, Lund, Søren, Henriksen, Anette, Rahbek-Nielsen, Henrik, Yang, Zhiru, Hilden, Ida

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Intact and cleaved plasma soluble urokinase receptor in patients with metastatic colorectal cancer treated with oxaliplatin with or without cetuximab von Tarpgaard, Line S., Christensen, Ib J., Høyer‐Hansen, Gunilla, Lund, Ida K., Guren, Tormod K., Glimelius, Bengt, Sorbye, Halfdan, Tveit, Kjell M., Nielsen, Hans Jørgen, Moreira, José M. A., Pfeiffer, Per, Brünner, Nils

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High-Throughput Sequencing-Based Investigation of Viruses in Human Cancers by Multienrichment Approach von Mollerup, Sarah, Asplund, Maria, Friis-Nielsen, Jens, Kjartansdóttir, Kristín Rós, Fridholm, Helena, Hansen, Thomas Arn, Herrera, José Alejandro Romero, Barnes, Christopher James, Jensen, Randi Holm, Richter, Stine Raith, Nielsen, Ida Broman, Pietroni, Carlotta, Alquezar-Planas, David E, Rey-Iglesia, Alba, Olsen, Pernille V S, Rajpert-De Meyts, Ewa, Groth-Pedersen, Line, von Buchwald, Christian, Jensen, David H, Gniadecki, Robert, Høgdall, Estrid, Langhoff, Jill Levin, Pete, Imre, Vereczkey, Ildikó, Baranyai, Zsolt, Dybkaer, Karen, Johnsen, Hans Erik, Steiniche, Torben, Hokland, Peter, Rosenberg, Jacob, Baandrup, Ulrik, Sicheritz-Pontén, Thomas, Willerslev, Eske, Brunak, Søren, Lund, Ole, Mourier, Tobias, Vinner, Lasse, Izarzugaza, Jose M G, Nielsen, Lars Peter, Hansen, Anders Johannes

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