The epigenetic and transcriptional landscape of neuroendocrine prostate cancer von Davies, Alastair, Zoubeidi, Amina, Selth, Luke A

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The androgen receptor is a tumor suppressor in estrogen receptor–positive breast cancer von Hickey, Theresa E., Selth, Luke A., Chia, Kee Ming, Laven-Law, Geraldine, Milioli, Heloisa H., Roden, Daniel, Jindal, Shalini, Hui, Mun, Finlay-Schultz, Jessica, Ebrahimie, Esmaeil, Birrell, Stephen N., Stelloo, Suzan, Iggo, Richard, Alexandrou, Sarah, Caldon, C. Elizabeth, Abdel-Fatah, Tarek M., Ellis, Ian O., Zwart, Wilbert, Palmieri, Carlo, Sartorius, Carol A., Swarbrick, Alex, Lim, Elgene, Carroll, Jason S., Tilley, Wayne D.

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Human DECR1 is an androgen-repressed survival factor that regulates PUFA oxidation to protect prostate tumor cells from ferroptosis von Nassar, Zeyad D, Mah, Chui Yan, Dehairs, Jonas, Burvenich, Ingrid Jg, Irani, Swati, Centenera, Margaret M, Helm, Madison, Shrestha, Raj K, Moldovan, Max, Don, Anthony S, Holst, Jeff, Scott, Andrew M, Horvath, Lisa G, Lynn, David J, Selth, Luke A, Hoy, Andrew J, Swinnen, Johannes V, Butler, Lisa M

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Androgen receptor signaling in castration-resistant prostate cancer: a lesson in persistence von Coutinho, Isabel, Day, Tanya K, Tilley, Wayne D, Selth, Luke A

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Novel Androgen Receptor Coregulator GRHL2 Exerts Both Oncogenic and Antimetastatic Functions in Prostate Cancer von Paltoglou, Steve, Das, Rajdeep, Townley, Scott L, Hickey, Theresa E, Tarulli, Gerard A, Coutinho, Isabel, Fernandes, Rayzel, Hanson, Adrienne R, Denis, Iza, Carroll, Jason S, Dehm, Scott M, Raj, Ganesh V, Plymate, Stephen R, Tilley, Wayne D, Selth, Luke A

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MicroRNA-194 Promotes Prostate Cancer Metastasis by Inhibiting SOCS2 von Das, Rajdeep, Gregory, Philip A, Fernandes, Rayzel C, Denis, Iza, Wang, Qingqing, Townley, Scott L, Zhao, Shuang G, Hanson, Adrienne R, Pickering, Marie A, Armstrong, Heather K, Lokman, Noor A, Ebrahimie, Esmaeil, Davicioni, Elai, Jenkins, Robert B, Karnes, R Jeffrey, Ross, Ashley E, Den, Robert B, Klein, Eric A, Chi, Kim N, Ramshaw, Hayley S, Williams, Elizabeth D, Zoubeidi, Amina, Goodall, Gregory J, Feng, Felix Y, Butler, Lisa M, Tilley, Wayne D, Selth, Luke A

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Novel Selective Agents for the Degradation of Androgen Receptor Variants to Treat Castration-Resistant Prostate Cancer von Ponnusamy, Suriyan, Coss, Christopher C, Thiyagarajan, Thirumagal, Watts, Kate, Hwang, Dong-Jin, He, Yali, Selth, Luke A, McEwan, Iain J, Duke, Charles B, Pagadala, Jayaprakash, Singh, Geetika, Wake, Robert W, Ledbetter, Christopher, Tilley, Wayne D, Moldoveanu, Tudor, Dalton, James T, Miller, Duane D, Narayanan, Ramesh

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Targeting chromatin binding regulation of constitutively active AR variants to overcome prostate cancer resistance to endocrine-based therapies von Chan, Siu Chiu, Selth, Luke A, Li, Yingming, Nyquist, Michael D, Miao, Lu, Bradner, James E, Raj, Ganesh V, Tilley, Wayne D, Dehm, Scott M

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Disrupting Androgen Receptor Signaling Induces Snail-Mediated Epithelial-Mesenchymal Plasticity in Prostate Cancer von Miao, Lu, Yang, Lin, Li, Rui, Rodrigues, Daniel N, Crespo, Mateus, Hsieh, Jer-Tsong, Tilley, Wayne D, de Bono, Johann, Selth, Luke A, Raj, Ganesh V

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Role of Androgen Receptor Variants in Prostate Cancer: Report from the 2017 Mission Androgen Receptor Variants Meeting von Luo, Jun, Attard, Gerhardt, Balk, Steven P., Bevan, Charlotte, Burnstein, Kerry, Cato, Laura, Cherkasov, Artem, De Bono, Johann S., Dong, Yan, Gao, Allen C., Gleave, Martin, Heemers, Hannelore, Kanayama, Mayuko, Kittler, Ralf, Lang, Joshua M., Lee, Richard J., Logothetis, Christopher J., Matusik, Robert, Plymate, Stephen, Sawyers, Charles L., Selth, Luke A., Soule, Howard, Tilley, Wayne, Weigel, Nancy L., Zoubeidi, Amina, Dehm, Scott M., Raj, Ganesh V.

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Transcript Elongation by RNA Polymerase II von Selth, Luke A, Sigurdsson, Stefan, Svejstrup, Jesper Q

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ELOVL5 Is a Critical and Targetable Fatty Acid Elongase in Prostate Cancer von Centenera, Margaret M, Scott, Julia S, Machiels, Jelle, Nassar, Zeyad D, Miller, Deanna C, Zinonos, Irene, Dehairs, Jonas, Burvenich, Ingrid J G, Zadra, Giorgia, Chetta, Paolo M, Bango, Clyde, Evergren, Emma, Ryan, Natalie K, Gillis, Joanna L, Mah, Chui Yan, Tieu, Terence, Hanson, Adrienne R, Carelli, Ryan, Bloch, Katarzyna, Panagopoulos, Vasilios, Waelkens, Etienne, Derua, Rita, Williams, Elizabeth D, Evdokiou, Andreas, Cifuentes-Rius, Anna, Voelcker, Nicolas H, Mills, Ian G, Tilley, Wayne D, Scott, Andrew M, Loda, Massimo, Selth, Luke A, Swinnen, Johannes V, Butler, Lisa M

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Opposing transcriptional programs of KLF5 and AR emerge during therapy for advanced prostate cancer von Che, Meixia, Chaturvedi, Aashi, Munro, Sarah A., Pitzen, Samuel P., Ling, Alex, Zhang, Weijie, Mentzer, Josh, Ku, Sheng-Yu, Puca, Loredana, Zhu, Yanyun, Bergman, Andries M., Severson, Tesa M., Forster, Colleen, Liu, Yuzhen, Hildebrand, Jacob, Daniel, Mark, Wang, Ting-You, Selth, Luke A., Hickey, Theresa, Zoubeidi, Amina, Gleave, Martin, Bareja, Rohan, Sboner, Andrea, Tilley, Wayne, Carroll, Jason S., Tan, Winston, Kohli, Manish, Yang, Rendong, Hsieh, Andrew C., Murugan, Paari, Zwart, Wilbert, Beltran, Himisha, Huang, R. Stephanie, Dehm, Scott M.

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Interplay between the androgen receptor signaling axis and microRNAs in prostate cancer von Fernandes, Rayzel C, Hickey, Theresa E, Tilley, Wayne D, Selth, Luke A

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A feedback loop between the androgen receptor and 6-phosphogluoconate dehydrogenase (6PGD) drives prostate cancer growth von Gillis, Joanna L, Hinneh, Josephine A, Ryan, Natalie K, Irani, Swati, Moldovan, Max, Quek, Lake-Ee, Shrestha, Raj K, Hanson, Adrienne R, Xie, Jianling, Hoy, Andrew J, Holst, Jeff, Centenera, Margaret M, Mills, Ian G, Lynn, David J, Selth, Luke A, Butler, Lisa M

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FOXA2 rewires AP-1 for transcriptional reprogramming and lineage plasticity in prostate cancer von Wang, Zifeng, Townley, Scott L., Zhang, Songqi, Liu, Mingyu, Li, Muqing, Labaf, Maryam, Patalano, Susan, Venkataramani, Kavita, Siegfried, Kellee R., Macoska, Jill A., Han, Dong, Gao, Shuai, Risbridger, Gail P., Taylor, Renea A., Lawrence, Mitchell G., He, Housheng Hansen, Selth, Luke A., Cai, Changmeng

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VULCAN integrates ChIP-seq with patient-derived co-expression networks to identify GRHL2 as a key co-regulator of ERa at enhancers in breast cancer von Holding, Andrew N, Giorgi, Federico M, Donnelly, Amanda, Cullen, Amy E, Nagarajan, Sankari, Selth, Luke A, Markowetz, Florian

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TSC-insensitive Rheb mutations induce oncogenic transformation through a combination of constitutively active mTORC1 signalling and proteome remodelling von Xie, Jianling, De Poi, Stuart P., Humphrey, Sean J., Hein, Leanne K., Bruning, John B., Pan, Wenru, Selth, Luke A., Sargeant, Timothy J., Proud, Christopher G.

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Post-transcriptional Gene Regulation by MicroRNA-194 Promotes Neuroendocrine Transdifferentiation in Prostate Cancer von Fernandes, Rayzel C., Toubia, John, Townley, Scott, Hanson, Adrienne R., Dredge, B. Kate, Pillman, Katherine A., Bert, Andrew G., Winter, Jean M., Iggo, Richard, Das, Rajdeep, Obinata, Daisuke, Sandhu, Shahneen, Risbridger, Gail P., Taylor, Renea A., Lawrence, Mitchell G., Butler, Lisa M., Zoubeidi, Amina, Gregory, Philip A., Tilley, Wayne D., Hickey, Theresa E., Goodall, Gregory J., Selth, Luke A.

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The landscape of alternative polyadenylation during EMT and its regulation by the RNA-binding protein Quaking von Neumann, Daniel P., Pillman, Katherine A., Dredge, B. Kate, Bert, Andrew G., Phillips, Caroline A., Lumb, Rachael, Ramani, Yesha, Bracken, Cameron P., Hollier, Brett G., Selth, Luke A., Beilharz, Traude H., Goodall, Gregory J., Gregory, Philip A.

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