Combination GITR targeting/PD-1 blockade with vaccination drives robust antigen-specific antitumor immunity von Villarreal, Daniel O, Chin, Diana, Smith, Melissa A, Luistro, Leopoldo L, Snyder, Linda A

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Targeting of CD122 enhances antitumor immunity by altering the tumor immune environment von Villarreal, Daniel O, Allegrezza, Michael J, Smith, Melissa A, Chin, Diana, Luistro, Leopoldo L, Snyder, Linda A

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Development and characterization of a preclinical ovarian carcinoma model to investigate the mechanism of acquired resistance to trastuzumab von LUISTRO, LEOPOLDO L, ROSINSKI, JAMES A, BIAN, HONGJIN, BISHAYEE, SUBAL, RAMESHWAR, PRANELA, PONZIO, NICHOLAS M, RITLAND, STEVE R

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Abstract 5567: In vivo administration of the STING agonist, JNJ-67544412, leads to complete regression of established murine subcutaneous tumors von Smith, Melissa, Chin, Diana, Chan, Szeman, Mahady, Sally, Campion, Liam, Morgan, Caitlin, Patel, Shefali, Chu, Gerald, Hughes, Anna, Bignan, Gilles, Connolly, Pete, Emanuel, Stuart, Packman, Kathryn, Luistro, Leopoldo L.

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Development and characterization of a preclinical ovarian carcinoma model to investigate the mechanism of acquired resistance to trastuzumab von LUISTRO, Leopoldo L, ROSINSKI, James A, HONGJIN BIAN, BISHAYEE, Subal, RAMESHWAR, Pranela, PONZIO, Nicholas M, RITLAND, Steve R

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ANTI- GPRC5D ANTIBODIES, BISPECIFIC ANTIGEN BINDING MOLECULES THAT BIND GPRC5D AND CD3, AND USES THEREOF von Gaudet, Francois, Pillarisetti, Kodandaram, Majewski, Nathan, Luistro, III, Leopoldo L, Attar, Ricardo, Li, Yingzhe, Mendonca, Mark, Tornetta, Mark, Edavettal, Suzanne, Teplyakov, Alexey, Chin, Diana

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Anti-GPRC5D antibodies, bispecific antigen binding molecules that bind GPRC5D and CD3, and uses thereof von Gaudet, Francois, Pillarisetti, Kodandaram, Majewski, Nathan, Luistro, III, Leopoldo L, Attar, Ricardo, Li, Yingzhe, Mendonca, Mark, Tornetta, Mark, Edavettal, Suzanne, Teplyakov, Alexey, Chin, Diana

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Anti-GPRC5D antibodies, bispecific antigen binding molecules that bind GPRC5D and CD3, and uses thereof von Gaudet, Francois, Pillarisetti, Kodandaram, Majewski, Nathan, Luistro, III, Leopoldo L, Attar, Ricardo, Li, Yingzhe, Mendonca, Mark, Tornetta, Mark, Edavettal, Suzanne, Teplyakov, Alexey, Chin, Diana

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Anti-GPRC5D antibodies, bispecific antigen binding molecules that bind GPRC5D and CD3, and uses thereof von Gaudet, Francois, Pillarisetti, Kodandaram, Majewski, Nathan, Luistro, III, Leopoldo L, Attar, Ricardo, Li, Yingzhe, Mendonca, Mark, Tornetta, Mark, Edavettal, Suzanne, Teplyakov, Alexey, Chin, Diana

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ANTI- GPRC5D ANTIBODIES, BISPECIFIC ANTIGEN BINDING MOLECULES THAT BIND GPRC5D AND CD3, AND USES THEREOF von Tornetta Mark, Teplyakov Alexey, Gaudet Francois, Li Yingzhe, Luistro, III Leopoldo L, Mendonca Mark, Majewski Nathan, Edavettal Suzanne, Pillarisetti Kodandaram, Chin Diana, Attar Ricardo

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A Novel Bispecific Antibody Targeting EGFR and cMet Is Effective against EGFR Inhibitor-Resistant Lung Tumors von Moores, Sheri L, Chiu, Mark L, Bushey, Barbara S, Chevalier, Kristen, Luistro, Leopoldo, Dorn, Keri, Brezski, Randall J, Haytko, Peter, Kelly, Thomas, Wu, Sheng-Jiun, Martin, Pauline L, Neijssen, Joost, Parren, Paul W H I, Schuurman, Janine, Attar, Ricardo M, Laquerre, Sylvie, Lorenzi, Matthew V, Anderson, G Mark

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Discovery of a Novel, First-in-Class Bfl-1 BH3 Mimetic with Pro-Apoptotic Activity von Derks, Maarten, Bryan, Marian C., Rockx, Cindy, Schults, Tamara, Verhulst, Tinne, Pietrak, Beth, Maehigashi, Tatsuya, Robertson, James C., DeMaria, Andrew H., Holt, Kimberly, Ji, Shaofei, Wong, Victoria, Bueters, Ruud, Koo, Seong Joo, Masure, Stefan, Bhogal, Balpreet, Kelly, Christopher B., Mitra, Kaushik, Luistro, Leopoldo, Shaffer, Paul L., Szewczuk, Lawrence, Elsayed, Yusri, Philippar, Ulrike

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Abstract 2179: Antitumor activity of JNJ-63576253 (TRC253), a small molecule antagonist of F877L mutant and wild-type androgen receptor von Bush, Tammy L., Ndikuyeze, Georges Habineza, Bignan, Gilles, Branch, Jonathan, Ondrus, Janine, Shi, Yifan, Luistro, Leopoldo, Hastings, James, Erhardt, Joseph, Hickson, Ian, Patel, Shefali, Connolly, Peter, Zhang, Zhuming, Bischoff, James, Rupnow, Brent, Gottardis, Marco, Packman, Kathryn

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Antitumor and antimetastatic activity of interleukin 12 against murine tumors von BRUNDA, M. J, LUISTRO, L, WARRIER, R. R, WRIGHT, R. B, HUBBARD, B. R, MURPHY, M, WOLF, S. F, GATELY, M. K

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Abstract A11: Activity of a bispecific antibody targeting EGFR and cMet with enhanced Fc effector function in EGFR mutant setting with cMet pathway activation von Soring, Keri L., Grugan, Katharine D., Breszki, Randall J., Pardinas, Jose, Luistro, Leopoldo, Bushey, Barbara, Neijssen, Joost, Parren, Paul, Schuurman, Janine, Anderson, Mark, Attar, Ricardo, Lorenzi, Matthew V., Chiu, Mark, Moores, Sheri

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Role of interferon-γ in mediating the antitumor efficacy of interleukin-12 von BRUNDA, M. J, LUISTRO, L, HENDRZAK, J. A, FOUNTOULAKIS, M, GAROTTA, G, GATELY, M. K

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Antitumor activity of interleukin 12 in preclinical models von BRUNDA, M. J, LUISTRO, L, RUMENNIK, L, WRIGHT, R. B, DVOROZNIAK, M, AGLIONE, A, WIGGINTON, J. M, WILTROUT, R. H, HENDRZAK, J. A, PALLERONI, A. V

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Anti- GPRC5D antibodies, bispecific antigen binding molecules that bind GPRC5D and CD3, and uses thereof von MAJEWSKI, Nathan, CHIN, Diana, LI, Yingzhe, MENDONCA, Mark, TORNETTA, Mark, PILLARISETTI, Kodandaram, EDAVETTAL, Suzanne, ATTAR, Ricardo, TEPLYAKOV, Alexey, LUISTRO, Leopoldo, GAUDET, Francois

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Interleukin-12: Murine Models of a Potent Antitumor Agent von BRUNDA, MICHAEL J., LUISTRO, LEOPOLDO, RUMENNIK, LEONID, WRIGHT, ROSEMARY B., WIGGINTON, JON M., WILTROUT, ROBERT H., HENDRZAK, JILL A., PALLERONI, ALICIA V.

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ANTI- GPRC5D ANTIBODIES, BISPECIFIC ANTIGEN BINDING MOLECULES THAT BIND GPRC5D AND CD3, AND USES THEREOF von MAJEWSKI, Nathan, CHIN, Diana, LI, Yingzhe, MENDONCA, Mark, TORNETTA, Mark, EDAVETTAL, Suzanne, PILLARISETTI, Kondandaram, ATTAR, Ricardo, TEPLYAKOV, Alexey, LUISTRO, Leopoldo, GAUDET, Francois

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