Adhesion G protein-coupled receptors: opportunities for drug discovery von Bassilana, Frederic, Nash, Mark, Ludwig, Marie-Gabrielle

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Regulation of pulmonary surfactant by the adhesion GPCR GPR116/ADGRF5 requires a tethered agonist-mediated activation mechanism von Bridges, James P, Safina, Caterina, Pirard, Bernard, Brown, Kari, Filuta, Alyssa, Panchanathan, Ravichandran, Bouhelal, Rochdi, Reymann, Nicole, Patel, Sejal, Seuwen, Klaus, Miller, William E, Ludwig, Marie-Gabrielle

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Regulation of breathing by CO2 requires the proton-activated receptor GPR4 in retrotrapezoid nucleus neurons von Kumar, Natasha N, Velic, Ana, Soliz, Jorge, Shi, Yingtang, Li, Keyong, Wang, Sheng, Weaver, Janelle L, Sen, Josh, Abbott, Stephen BG, Lazarenko, Roman M, Ludwig, Marie-Gabrielle, Perez-Reyes, Edward, Mohebbi, Nilufar, Bettoni, Carla, Gassmann, Max, Suply, Thomas, Seuwen, Klaus, Guyenet, Patrice G, Wagner, Carsten A, Bayliss, Douglas A

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Proton detection and breathing regulation by the retrotrapezoid nucleus von Guyenet, Patrice G., Bayliss, Douglas A., Stornetta, Ruth L., Ludwig, Marie‐Gabrielle, Kumar, Natasha N., Shi, Yingtang, Burke, Peter G. R., Kanbar, Roy, Basting, Tyler M., Holloway, Benjamin B., Wenker, Ian C.

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Transcriptional regulation and functional characterization of the oxysterol/EBI2 system in primary human macrophages von Preuss, Inga, Ludwig, Marie-Gabrielle, Baumgarten, Birgit, Bassilana, Frederic, Gessier, Francois, Seuwen, Klaus, Sailer, Andreas W.

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The proton-activated ovarian cancer G protein-coupled receptor 1 (OGR1) is responsible for renal calcium loss during acidosis von Imenez Silva, Pedro Henrique, Katamesh-Benabbas, Chahira, Chan, Kessara, Pastor Arroyo, Eva Maria, Knöpfel, Thomas, Bettoni, Carla, Ludwig, Marie-Gabrielle, Gasser, Jürg A., Brandao-Burch, Andrea, Arnett, Timothy R., Bonny, Olivier, Seuwen, Klaus, Wagner, Carsten Alexander

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Multidimensional pooled shRNA screens in human THP-1 cells identify candidate modulators of macrophage polarization von Surdziel, Ewa, Clay, Ieuan, Nigsch, Florian, Thiemeyer, Anke, Allard, Cyril, Hoffman, Gregory, Reece-Hoyes, John S, Phadke, Tanushree, Gambert, Romain, Keller, Caroline Gubser, Ludwig, Marie-Gabrielle, Baumgarten, Birgit, Frederiksen, Mathias, Schübeler, Dirk, Seuwen, Klaus, Bouwmeester, Tewis, Fodor, Barna D

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Interleukin-4-Clicked Surfaces Drive M2 Macrophage Polarization von Lühmann, Tessa, Spieler, Valerie, Werner, Vera, Ludwig, Marie-Gabrielle, Fiebig, Juliane, Mueller, Thomas D., Meinel, Lorenz

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Proton-sensing G-protein-coupled receptors von Seuwen, Klaus, Ludwig, Marie-Gabrielle, Vanek, Miroslava, Guerini, Danilo, Gasser, Jürg A, Jones, Carol E, Junker, Uwe, Hofstetter, Hans, Wolf, Romain M

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Orphan G protein-coupled receptor GPR116 regulates pulmonary surfactant pool size von Bridges, James P, Ludwig, Marie-Gabrielle, Mueller, Matthias, Kinzel, Bernd, Sato, Atsuyasu, Xu, Yan, Whitsett, Jeffrey A, Ikegami, Machiko

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The pH-sensing receptor OGR1 improves barrier function of epithelial cells and inhibits migration in an acidic environment von de Vallière, Cheryl, Vidal, Solange, Clay, Ieuan, Jurisic, Giorgia, Tcymbarevich, Irina, Lang, Silvia, Ludwig, Marie-Gabrielle, Okoniewski, Michal, Eloranta, Jyrki J, Kullak-Ublick, Gerd A, Wagner, Carsten A, Rogler, Gerhard, Seuwen, Klaus

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Exploring Glucocorticoid Receptor Agonists Mechanism of Action Through Mass Cytometry and Radial Visualizations von Abraham, Yann, Gerrits, Bertran, Ludwig, Marie‐Gabrielle, Rebhan, Michael, Gubser Keller, Caroline

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The adhesion GPCR GPR116/ADGRF5 has a dual function in pancreatic islets regulating somatostatin release and islet development von Röthe, Juliane, Kraft, Robert, Ricken, Albert, Kaczmarek, Isabell, Matz-Soja, Madlen, Winter, Karsten, Dietzsch, André Nguyen, Buchold, Julia, Ludwig, Marie-Gabrielle, Liebscher, Ines, Schöneberg, Torsten, Thor, Doreen

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Reduced pathological angiogenesis and tumor growth in mice lacking GPR4, a proton sensing receptor von Wyder, Lorenza, Suply, Thomas, Ricoux, Bérangère, Billy, Eric, Schnell, Christian, Baumgarten, Birgit U., Maira, Sauveur Michel, Koelbing, Claudia, Ferretti, Mireille, Kinzel, Bernd, Müller, Matthias, Seuwen, Klaus, Ludwig, Marie-Gabrielle

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The Proton-activated G Protein Coupled Receptor OGR1 Acutely Regulates the Activity of Epithelial Proton Transport Proteins von Mohebbi, Nilufar, Benabbas, Chahira, Vidal, Solange, Daryadel, Arezoo, Bourgeois, Soline, Velic, Ana, Ludwig, Marie-Gabrielle, Seuwen, Klaus, Wagner, Carsten A.

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Glucocorticoid-loaded liposomes induce a pro-resolution phenotype in human primary macrophages to support chronic wound healing von Gauthier, Anne, Fisch, Andreas, Seuwen, Klaus, Baumgarten, Birgit, Ruffner, Heinz, Aebi, Alexandra, Rausch, Martin, Kiessling, Fabian, Bartneck, Matthias, Weiskirchen, Ralf, Tacke, Frank, Storm, Gert, Lammers, Twan, Ludwig, Marie-Gabrielle

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Receptors for Protons or Lipid Messengers or Both? von SEUWEN, KLAUS, LUDWIG, MARIE-GABRIELLE, WOLF, ROMAIN M.

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Targeting interleukin-4 to the arthritic joint von Spieler, Valerie, Ludwig, Marie-Gabrielle, Dawson, Janet, Tigani, Bruno, Littlewood-Evans, Amanda, Safina, Caterina, Ebersbach, Hilmar, Seuwen, Klaus, Raschig, Martina, ter Mors, Björn, Müller, Thomas D., Meinel, Lorenz, Lühmann, Tessa

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G Protein-coupled pH-sensing Receptor OGR1 Is a Regulator of Intestinal Inflammation von de Vallière, Cheryl, Wang, Yu, Eloranta, Jyrki J, Vidal, Solange, Clay, Ieuan, Spalinger, Marianne R, Tcymbarevich, Irina, Terhalle, Anne, Ludwig, Marie-Gabrielle, Suply, Thomas, Fried, Michael, Kullak-Ublick, Gerd A, Frey-Wagner, Isabelle, Scharl, Michael, Seuwen, Klaus, Wagner, Carsten A, Rogler, Gerhard

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The Proton-Activated Receptor GPR4 Modulates Glucose Homeostasis by Increasing Insulin Sensitivity von Giudici, Luca, Velic, Ana, Daryadel, Arezoo, Bettoni, Carla, Mohebbi, Nilufar, Suply, Thomas, Seuwen, Klaus, Ludwig, Marie-Gabrielle, Wagner, Carsten A.

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