The Cell-Cycle State of Stem Cells Determines Cell Fate Propensity von Pauklin, Siim, Vallier, Ludovic

Volltext

Single-cell transcriptomic characterization of a gastrulating human embryo von Tyser, Richard C. V., Mahammadov, Elmir, Nakanoh, Shota, Vallier, Ludovic, Scialdone, Antonio, Srinivas, Shankar

Volltext

Initiation of stem cell differentiation involves cell cycle-dependent regulation of developmental genes by Cyclin D von Pauklin, Siim, Madrigal, Pedro, Bertero, Alessandro, Vallier, Ludovic

Volltext

Isolation and propagation of primary human cholangiocyte organoids for the generation of bioengineered biliary tissue von Tysoe, Olivia C., Justin, Alexander W., Brevini, Teresa, Chen, Si Emma, Mahbubani, Krishnaa T., Frank, Anna K., Zedira, Hajer, Melum, Espen, Saeb-Parsy, Kourosh, Markaki, Athina E., Vallier, Ludovic, Sampaziotis, Fotios

Volltext

Genetic background drives transcriptional variation in human induced pluripotent stem cells von Rouhani, Foad, Kumasaka, Natsuhiko, de Brito, Miguel Cardoso, Bradley, Allan, Vallier, Ludovic, Gaffney, Daniel

Volltext

Production of hepatocyte-like cells from human pluripotent stem cells von Hannan, Nicholas R F, Segeritz, Charis-Patricia, Touboul, Thomas, Vallier, Ludovic

Volltext

Directed differentiation of human induced pluripotent stem cells into functional cholangiocyte-like cells von Sampaziotis, Fotios, de Brito, Miguel Cardoso, Geti, Imbisaat, Bertero, Alessandro, Hannan, Nicholas RF, Vallier, Ludovic

Volltext

Activin/Nodal and FGF pathways cooperate to maintain pluripotency of human embryonic stem cells von Vallier, Ludovic, Alexander, Morgan, Pedersen, Roger A

Volltext

Serum-Free and Feeder-Free Culture Conditions for Human Embryonic Stem Cells von Vallier, Ludovic

Volltext

DNA methylation defines regional identity of human intestinal epithelial organoids and undergoes dynamic changes during development von Kraiczy, Judith, Nayak, Komal M, Howell, Kate J, Ross, Alexander, Forbester, Jessica, Salvestrini, Camilla, Mustata, Roxana, Perkins, Sally, Andersson-Rolf, Amanda, Leenen, Esther, Liebert, Anke, Vallier, Ludovic, Rosenstiel, Philip C, Stegle, Oliver, Dougan, Gordon, Heuschkel, Robert, Koo, Bon-Kyoung, Zilbauer, Matthias

Volltext

Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation von Sampaziotis, Fotios, Cardoso de Brito, Miguel, Madrigal, Pedro, Bertero, Alessandro, Saeb-Parsy, Kourosh, Soares, Filipa A C, Schrumpf, Elisabeth, Melum, Espen, Karlsen, Tom H, Bradley, J Andrew, Gelson, William T H, Davies, Susan, Baker, Alastair, Kaser, Arthur, Alexander, Graeme J, Hannan, Nicholas R F, Vallier, Ludovic

Volltext

Transplantation of Expanded Fetal Intestinal Progenitors Contributes to Colon Regeneration after Injury von Fordham, Robert P., Yui, Shiro, Hannan, Nicholas R.F., Soendergaard, Christoffer, Madgwick, Alison, Schweiger, Pawel J., Nielsen, Ole H., Vallier, Ludovic, Pedersen, Roger A., Nakamura, Tetsuya, Watanabe, Mamoru, Jensen, Kim B.

Volltext

An in vitro stem cell model of human epiblast and yolk sac interaction von Mackinlay, Kirsty Ml, Weatherbee, Bailey At, Souza Rosa, Viviane, Handford, Charlotte E, Hudson, George, Coorens, Tim, Pereira, Lygia V, Behjati, Sam, Vallier, Ludovic, Shahbazi, Marta N, Zernicka-Goetz, Magdalena

Volltext

TGFβ signalling is required to maintain pluripotency of human naïve pluripotent stem cells von Osnato, Anna, Brown, Stephanie, Krueger, Christel, Andrews, Simon, Collier, Amanda J, Nakanoh, Shota, Quiroga Londoño, Mariana, Wesley, Brandon T, Muraro, Daniele, Brumm, A Sophie, Niakan, Kathy K, Vallier, Ludovic, Ortmann, Daniel, Rugg-Gunn, Peter J

Volltext

Combined single-cell profiling of expression and DNA methylation reveals splicing regulation and heterogeneity von Linker, Stephanie M, Urban, Lara, Clark, Stephen J, Chhatriwala, Mariya, Amatya, Shradha, McCarthy, Davis J, Ebersberger, Ingo, Vallier, Ludovic, Reik, Wolf, Stegle, Oliver, Bonder, Marc Jan

Volltext

Simultaneous depletion of RB, RBL1 and RBL2 affects endoderm differentiation of human embryonic stem cells von Shota Nakanoh, Juned Kadiwala, Laetitia Pinte, Carola Maria Morell, An-Sofie Lenaerts, Ludovic Vallier

Volltext

Potential of human induced pluripotent stem cells in studies of liver disease von Sampaziotis, Fotios, Segeritz, Charis‐Patricia, Vallier, Ludovic

Volltext

Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells von Yusa, Kosuke, Rashid, S. Tamir, Strick-Marchand, Helene, Varela, Ignacio, Liu, Pei-Qi, Paschon, David E., Miranda, Elena, Ordóñez, Adriana, Hannan, Nicholas R. F., Rouhani, Foad J., Darche, Sylvie, Alexander, Graeme, Marciniak, Stefan J., Fusaki, Noemi, Hasegawa, Mamoru, Holmes, Michael C., Di Santo, James P., Lomas, David A., Bradley, Allan, Vallier, Ludovic

Volltext

Senescence impairs successful reprogramming to pluripotent stem cells von Banito, Ana, Rashid, Sheikh T, Acosta, Juan Carlos, Li, SiDe, Pereira, Carlos F, Geti, Imbisaat, Pinho, Sandra, Silva, Jose C, Azuara, Veronique, Walsh, Martin, Vallier, Ludovic, Gil, Jesús

Volltext

Analysis of endothelial-to-haematopoietic transition at the single cell level identifies cell cycle regulation as a driver of differentiation von Canu, Giovanni, Athanasiadis, Emmanouil, Grandy, Rodrigo A, Garcia-Bernardo, Jose, Strzelecka, Paulina M, Vallier, Ludovic, Ortmann, Daniel, Cvejic, Ana

Volltext