Mechanically activated Piezo1 channels of cardiac fibroblasts stimulate p38 mitogen-activated protein kinase activity and interleukin-6 secretion von Blythe, Nicola M., Muraki, Katsuhiko, Ludlow, Melanie J., Stylianidis, Vasili, Gilbert, Hamish T.J., Evans, Elizabeth L., Cuthbertson, Kevin, Foster, Richard, Swift, Joe, Li, Jing, Drinkhill, Mark J., van Nieuwenhoven, Frans A., Porter, Karen E., Beech, David J., Turner, Neil A.

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Piezo1 channels sense whole body physical activity to reset cardiovascular homeostasis and enhance performance von Rode, Baptiste, Shi, Jian, Endesh, Naima, Drinkhill, Mark J., Webster, Peter J., Lotteau, Sabine J., Bailey, Marc A., Yuldasheva, Nadira Y., Ludlow, Melanie J., Cubbon, Richard M., Li, Jing, Futers, T. Simon, Morley, Lara, Gaunt, Hannah J., Marszalek, Katarzyna, Viswambharan, Hema, Cuthbertson, Kevin, Baxter, Paul D., Foster, Richard, Sukumar, Piruthivi, Weightman, Andrew, Calaghan, Sarah C., Wheatcroft, Stephen B., Kearney, Mark T., Beech, David J.

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(−)-Englerin A is a Potent and Selective Activator of TRPC4 and TRPC5 Calcium Channels von Akbulut, Yasemin, Gaunt, Hannah J., Muraki, Katsuhiko, Ludlow, Melanie J., Amer, Mohamed S., Bruns, Alexander, Vasudev, Naveen S., Radtke, Lea, Willot, Matthieu, Hahn, Sven, Seitz, Tobias, Ziegler, Slava, Christmann, Mathias, Beech, David J., Waldmann, Herbert

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Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels von Rubaiy, Hussein N., Ludlow, Melanie J., Henrot, Matthias, Gaunt, Hannah J., Miteva, Katarina, Cheung, Sin Ying, Tanahashi, Yasuyuki, Hamzah, Nurasyikin, Musialowski, Katie E., Blythe, Nicola M., Appleby, Hollie L., Bailey, Marc A., McKeown, Lynn, Taylor, Roger, Foster, Richard, Waldmann, Herbert, Nussbaumer, Peter, Christmann, Mathias, Bon, Robin S., Muraki, Katsuhiko, Beech, David J.

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PIEZO1 and PECAM1 interact at cell-cell junctions and partner in endothelial force sensing von Chuntharpursat-Bon, Eulashini, Povstyan, Oleksandr V., Ludlow, Melanie J., Carrier, David J., Debant, Marjolaine, Shi, Jian, Gaunt, Hannah J., Bauer, Claudia C., Curd, Alistair, Simon Futers, T., Baxter, Paul D., Peckham, Michelle, Muench, Stephen P., Adamson, Antony, Humphreys, Neil, Tumova, Sarka, Bon, Robin S., Cubbon, Richard, Lichtenstein, Laeticia, Beech, David J.

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Natural and synthetic flavonoid modulation of TRPC5 channels von Naylor, Jacqueline, Minard, Aisling, Gaunt, Hannah J, Amer, Mohamed S, Wilson, Lesley A, Migliore, Marco, Cheung, Sin Y, Rubaiy, Hussein N, Blythe, Nicola M, Musialowski, Katie E, Ludlow, Melanie J, Evans, William D, Green, Ben L, Yang, Hongjun, You, Yun, Li, Jing, Fishwick, Colin W G, Muraki, Katsuhiko, Beech, David J, Bon, Robin S

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Endocytosis of HERG is clathrin-independent and involves arf6 von Karnik, Rucha, Ludlow, Melanie J, Abuarab, Nada, Smith, Andrew J, Hardy, Matthew E L, Elliott, David J S, Sivaprasadarao, Asipu

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Yoda1 analogue (Dooku1) which antagonizes Yoda1‐evoked activation of Piezo1 and aortic relaxation von Evans, Elizabeth L, Cuthbertson, Kevin, Endesh, Naima, Rode, Baptiste, Blythe, Nicola M, Hyman, Adam J, Hall, Sally J, Gaunt, Hannah J, Ludlow, Melanie J, Foster, Richard, Beech, David J

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Functional Characterization of Intracellular Dictyostelium discoideum P2X Receptors von Ludlow, Melanie J., Durai, Latha, Ennion, Steven J.

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Piezo1 integration of vascular architecture with physiological force von Li, Jing, Hou, Bing, Tumova, Sarka, Muraki, Katsuhiko, Bruns, Alexander, Ludlow, Melanie J., Sedo, Alicia, Hyman, Adam J., McKeown, Lynn, Young, Richard S., Yuldasheva, Nadira Y., Majeed, Yasser, Wilson, Lesley A., Rode, Baptiste, Bailey, Marc A., Kim, Hyejeong R., Fu, Zhaojun, Carter, Deborah A. L., Bilton, Jan, Imrie, Helen, Ajuh, Paul, Dear, T. Neil, Cubbon, Richard M., Kearney, Mark T., Prasad, K. Raj, Evans, Paul C., Ainscough, Justin F. X., Beech, David J.

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Modeling of full-length Piezo1 suggests importance of the proximal N-terminus for dome structure von Chong, Jiehan, De Vecchis, Dario, Hyman, Adam J., Povstyan, Oleksandr V., Ludlow, Melanie J., Shi, Jian, Beech, David J., Kalli, Antreas C.

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Improved PIEZO1 agonism through 4‐benzoic acid modification of Yoda1 von Parsonage, Gregory, Cuthbertson, Kevin, Endesh, Naima, Murciano, Nicoletta, Hyman, Adam J., Revill, Charlotte H., Povstyan, Oleksandr V., Chuntharpursat‐Bon, Eulashini, Debant, Marjolaine, Ludlow, Melanie J., Futers, Timothy Simon, Lichtenstein, Laeticia, Kinsella, Jacob A., Bartoli, Fiona, Rotordam, Maria Giustina, Becker, Nadine, Brüggemann, Andrea, Foster, Richard, Beech, David J.

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A high-throughput electrophysiology assay to study the response of PIEZO1 to mechanical stimulation von Murciano, Nicoletta, Rotordam, Maria Giustina, Becker, Nadine, Ludlow, Melanie J, Parsonage, Gregory, Darras, Alexis, Kaestner, Lars, Beech, David J, George, Michael, Fertig, Niels, Rapedius, Markus, Brüggemann, Andrea

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RBCs prevent rapid PIEZO1 inactivation and expose slow deactivation as a mechanism of dehydrated hereditary stomatocytosis von Evans, Elizabeth L., Povstyan, Oleksandr V., De Vecchis, Dario, Macrae, Fraser, Lichtenstein, Laeticia, Futers, T. Simon, Parsonage, Gregory, Humphreys, Neil E., Adamson, Antony, Kalli, Antreas C., Ludlow, Melanie J., Beech, David J.

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Tonantzitlolone is a nanomolar potency activator of transient receptor potential canonical 1/4/5 channels von Rubaiy, Hussein N, Ludlow, Melanie J, Siems, Karsten, Norman, Katherine, Foster, Richard, Wolf, Dietmar, Beutler, John A, Beech, David J

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Potent, selective, and subunit‐dependent activation of TRPC5 channels by a xanthine derivative von Minard, Aisling, Bauer, Claudia C., Chuntharpursat‐Bon, Eulashini, Pickles, Isabelle B., Wright, David J., Ludlow, Melanie J., Burnham, Matthew P., Warriner, Stuart L., Beech, David J., Muraki, Katsuhiko, Bon, Robin S.

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(−)-Englerin A-evoked Cytotoxicity Is Mediated by Na+ Influx and Counteracted by Na+/K+-ATPase von Ludlow, Melanie J., Gaunt, Hannah J., Rubaiy, Hussein N., Musialowski, Katie E., Blythe, Nicola M., Vasudev, Naveen S., Muraki, Katsuhiko, Beech, David J.

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Pico145 - powerful new tool for TRPC1/4/5 channels von Rubaiy, Hussein N., Ludlow, Melanie J., Bon, Robin S., Beech, David J.

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Purinergic-mediated Ca2+ influx in Dictyostelium discoideum von Ludlow, Melanie J, Traynor, David, Fisher, Paul R, Ennion, Steven J

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Mechanical and pharmacological activation of PIEZO1 channels characterized by high throughput electrophysiology von Bruggemann, Andrea, Murciano, Nicoletta, Giustina Rotordam, Maria, Rapedius, Markus, Becker, Nadine, Ludlow, Melanie J., Parsonage, Gregory, Cuthbertson, Kevin, Foster, Richard, Beech, David J.

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