RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth von Hatzivassiliou, Georgia, Song, Kyung, Yen, Ivana, Brandhuber, Barbara J., Anderson, Daniel J., Alvarado, Ryan, Ludlam, Mary J. C., Stokoe, David, Gloor, Susan L., Vigers, Guy, Morales, Tony, Aliagas, Ignacio, Liu, Bonnie, Sideris, Steve, Hoeflich, Klaus P., Jaiswal, Bijay S., Seshagiri, Somasekar, Koeppen, Hartmut, Belvin, Marcia, Friedman, Lori S., Malek, Shiva

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Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity von Maurer, Till, Garrenton, Lindsay S, Oh, Angela, Pitts, Keith, Anderson, Daniel J, Skelton, Nicholas J, Fauber, Benjamin P, Pan, Borlan, Malek, Shiva, Stokoe, David, Ludlam, Mary J. C, Bowman, Krista K, Wu, Jiansheng, Giannetti, Anthony M, Starovasnik, Melissa A, Mellman, Ira, Jackson, Peter K, Rudolph, Joachim, Wang, Weiru, Fang, Guowei

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Axl as a potential therapeutic target in cancer: role of Axl in tumor growth, metastasis and angiogenesis von Li, Y, Ye, X, Tan, C, Hongo, J -A, Zha, J, Liu, J, Kallop, D, Ludlam, M J C, Pei, L

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Mechanism of MEK inhibition determines efficacy in mutant KRAS- versus BRAF-driven cancers von Hatzivassiliou, Georgia, Haling, Jacob R., Chen, Huifen, Song, Kyung, Price, Steve, Heald, Robert, Hewitt, Joanne F. M., Zak, Mark, Peck, Ariana, Orr, Christine, Merchant, Mark, Hoeflich, Klaus P., Chan, Jocelyn, Luoh, Shiuh-Ming, Anderson, Daniel J., Ludlam, Mary J. C., Wiesmann, Christian, Ultsch, Mark, Friedman, Lori S., Malek, Shiva, Belvin, Marcia

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Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+Ly6C+ granulocytes von Kowanetz, Marcin, Wu, Xiumin, Lee, John, Tan, Martha, Hagenbeek, Thijs, Qu, Xueping, Yu, Lanlan, Ross, Jed, Korsisaari, Nina, Cao, Tim, Bou-Reslan, Hani, Kallop, Dara, Weimer, Robby, Ludlam, Mary J. C., Kaminker, Joshua S., Modrusan, Zora, van Bruggen, Nicholas, Peale, Franklin V., Carano, Richard, Meng, Y. Gloria, Ferrara, Napoleone

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Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7 von Wertz, Ingrid E., Kusam, Saritha, Lam, Cynthia, Okamoto, Toru, Sandoval, Wendy, Anderson, Daniel J., Helgason, Elizabeth, Ernst, James A., Eby, Mike, Liu, Jinfeng, Belmont, Lisa D., Kaminker, Joshua S., O’Rourke, Karen M., Pujara, Kanan, Kohli, Pawan Bir, Johnson, Adam R., Chiu, Mark L., Lill, Jennie R., Jackson, Peter K., Fairbrother, Wayne J., Seshagiri, Somasekar, Ludlam, Mary J. C., Leong, Kevin G., Dueber, Erin C., Maecker, Heather, Huang, David C. S., Dixit, Vishva M.

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Cell segmentation in images without structural fluorescent labels von Zyss, Daniel, Ribeiro, Susana A, Ludlam, Mary J C, Walter, Thomas, Fehri, Amin

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Potent and selective small-molecule MCL-1 inhibitors demonstrate on-target cancer cell killing activity as single agents and in combination with ABT-263 (navitoclax) von Leverson, J D, Zhang, H, Chen, J, Tahir, S K, Phillips, D C, Xue, J, Nimmer, P, Jin, S, Smith, M, Xiao, Y, Kovar, P, Tanaka, A, Bruncko, M, Sheppard, G S, Wang, L, Gierke, S, Kategaya, L, Anderson, D J, Wong, C, Eastham-Anderson, J, Ludlam, M J C, Sampath, D, Fairbrother, W J, Wertz, I, Rosenberg, S H, Tse, C, Elmore, S W, Souers, A J

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Live-cell microscopy reveals small molecule inhibitor effects on MAPK pathway dynamics von Anderson, Daniel J, Durieux, Jenni K, Song, Kyung, Alvarado, Ryan, Jackson, Peter K, Hatzivassiliou, Georgia, Ludlam, Mary J C

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Bcl-2, Bcl-xL, and Bcl-w are not equivalent targets of ABT-737 and navitoclax (ABT-263) in lymphoid and leukemic cells von Mérino, Delphine, Khaw, Seong L., Glaser, Stefan P., Anderson, Daniel J., Belmont, Lisa D., Wong, Chihunt, Yue, Peng, Robati, Mikara, Phipson, Belinda, Fairlie, Walter D., Lee, Erinna F., Campbell, Kirsteen J., Vandenberg, Cassandra J., Cory, Suzanne, Roberts, Andrew W., Ludlam, Mary J.C., Huang, David C.S., Bouillet, Philippe

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Universal features of localized eigenstates in disordered systems von Ludlam, J J, Taraskin, S N, Elliott, S R, Drabold, D A

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Direct visualization of Bcl-2 family protein interactions using live cell fluorescent protein redistribution assays von Wong, C, Anderson, D J, Lee, E F, Fairlie, W D, Ludlam, M J C

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Pegylated kunitz domain inhibitor suppresses hepsin-mediated invasive tumor growth and metastasis von Li, Wei, Wang, Bu-Er, Moran, Paul, Lipari, Terry, Ganesan, Rajkumar, Corpuz, Racquel, Ludlam, Mary J C, Gogineni, Alvin, Koeppen, Hartmut, Bunting, Stuart, Gao, Wei-Qiang, Kirchhofer, Daniel

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Synergy in spreading processes: from exploitative to explorative foraging strategies von Pérez-Reche, Francisco J, Ludlam, Jonathan J, Taraskin, Sergei N, Gilligan, Christopher A

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Applications of percolation theory to fungal spread with synergy von Ludlam, Jonathan J., Gibson, Gavin J., Otten, Wilfred, Gilligan, Christopher A.

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New and regenerated production in the South Atlantic off Brazil von Metzler, Patricia M., Glibert, Patricia M., Gaeta, Salvador A., Ludlam, John M.

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Disorder-induced vibrational localization von Ludlam, J. J., Taraskin, S. N., Elliott, S. R.

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The Study Abroad Experiences of Secondary Agriculture, Food and Natural Resources Students von Ludlam, Samantha, McKim, Aaron, McKendree, Robert

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Similarity of bacteriorhodopsin structural changes triggered by chromophore removal and light-driven proton transport von Ludlam, Gary J., Rothschild, Kenneth J.

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Contrasting effects of substrate and grazer manipulations on picoplankton in oceanic and coastal waters off Brazil von Metzler, Patricia M., Glibert, Patricia M., Gaeta, Salvador A., Ludlam, John M.

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