Targeting the Proteasome-Associated Deubiquitinating Enzyme USP14 Impairs Melanoma Cell Survival and Overcomes Resistance to MAPK-Targeting Therapies von Didier, Robin, Mallavialle, Aude, Ben Jouira, Rania, Domdom, Marie Angela, Tichet, Mélanie, Auberger, Patrick, Luciano, Frédéric, Ohanna, Mickael, Tartare-Deckert, Sophie, Deckert, Marcel

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The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia von Fenouille, Nina, Bassil, Christopher F, Ben-Sahra, Issam, Benajiba, Lina, Alexe, Gabriela, Ramos, Azucena, Pikman, Yana, Conway, Amy S, Burgess, Michael R, Li, Qing, Luciano, Frédéric, Auberger, Patrick, Galinsky, Ilene, DeAngelo, Daniel J, Stone, Richard M, Zhang, Yi, Perkins, Archibald S, Shannon, Kevin, Hemann, Michael T, Puissant, Alexandre, Stegmaier, Kimberly

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Cleavage of Mcl-1 by caspases impaired its ability to counteract Bim-induced apoptosis von HERRANT, Magali, JACQUEL, Arnaud, MARCHETTI, Sandrine, BELHACENE, Nathalie, COLOSETTI, Pascal, LUCIANO, Frédéric, AUBERGER, Patrick

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Deciphering the Role of Oncogenic MITFE318K in Senescence Delay and Melanoma Progression von Bonet, Caroline, Luciani, Flavie, Ottavi, Jean-François, Leclerc, Justine, Jouenne, Fanélie-Marie, Boncompagni, Marina, Bille, Karine, Hofman, Véronique, Bossis, Guillaume, Marco de Donatis, Gian, Strub, Thomas, Cheli, Yann, Ohanna, Mickaël, Luciano, Frédéric, Marchetti, Sandrine, Rocchi, Stéphane, Birling, Marie-Christine, Avril, Marie-Françoise, Poulalhon, Nicolas, Luc, Thomas, Hofman, Paul, Lacour, Jean-Philippe, Davidson, Irwin, Bressac-de Paillerets, Brigitte, Ballotti, Robert, Marine, Jean-Christophe, Bertolotto, Corine

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Implication and Regulation of AMPK during Physiological and Pathological Myeloid Differentiation von Jacquel, Arnaud, Luciano, Frederic, Robert, Guillaume, Auberger, Patrick

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Resveratrol Promotes Autophagic Cell Death in Chronic Myelogenous Leukemia Cells via JNK-Mediated p62/SQSTM1 Expression and AMPK Activation von PUISSANT, Alexandre, ROBERT, Guillaume, FENOUILLE, Nina, LUCIANO, Frederic, CASSUTO, Jill-Patrice, RAYNAUD, Sophie, AUBERGER, Patrick

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IL-34 and CSF-1 display an equivalent macrophage differentiation ability but a different polarization potential von Boulakirba, Sonia, Pfeifer, Anja, Mhaidly, Rana, Obba, Sandrine, Goulard, Michael, Schmitt, Thomas, Chaintreuil, Paul, Calleja, Anne, Furstoss, Nathan, Orange, François, Lacas-Gervais, Sandra, Boyer, Laurent, Marchetti, Sandrine, Verhoeyen, Els, Luciano, Frederic, Robert, Guillaume, Auberger, Patrick, Jacquel, Arnaud

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Unveiling CXCR2 as a promising therapeutic target in renal cell carcinoma: exploring the immunotherapeutic paradigm shift through its inhibition by RCT001 von Montemagno, Christopher, Jacquel, Arnaud, Pandiani, Charlotte, Rastoin, Olivia, Dawaliby, Rosie, Schmitt, Thomas, Bourgoin, Maxence, Palenzuela, Héliciane, Rossi, Anne-Laure, Ambrosetti, Damien, Durivault, Jerome, Luciano, Frederic, Borchiellini, Delphine, Le Du, Julie, Gonçalves, Leticia Christina Pires, Auberger, Patrick, Benhida, Rachid, Kinget, Lisa, Beuselinck, Benoit, Ronco, Cyril, Pagès, Gilles, Dufies, Maeva

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GAPDH Overexpression in the T Cell Lineage Promotes Angioimmunoblastic T Cell Lymphoma through an NF-κB-Dependent Mechanism von Mondragón, Laura, Mhaidly, Rana, De Donatis, Gian Marco, Tosolini, Marie, Dao, Pascal, Martin, Anthony R., Pons, Caroline, Chiche, Johanna, Jacquin, Marie, Imbert, Véronique, Proïcs, Emma, Boyer, Laurent, Doye, Anne, Luciano, Frédéric, Neels, Jaap G., Coutant, Frédéric, Fabien, Nicole, Sormani, Laura, Rubio-Patiño, Camila, Bossowski, Jozef P., Muller, Florian, Marchetti, Sandrine, Villa, Elodie, Peyron, Jean-François, Gaulard, Philippe, Lemonnier, François, Asnafi, Vahid, Genestier, Laurent, Benhida, Rachid, Fournié, Jean-Jacques, Passeron, Thierry, Ricci, Jean-Ehrland, Verhoeyen, Els

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Bax inhibitor‐1 protects from nonalcoholic steatohepatitis by limiting inositol‐requiring enzyme 1 alpha signaling in mice von Lebeaupin, Cynthia, Vallée, Déborah, Rousseau, Déborah, Patouraux, Stéphanie, Bonnafous, Stéphanie, Adam, Gilbert, Luciano, Frederic, Luci, Carmelo, Anty, Rodolphe, Iannelli, Antonio, Marchetti, Sandrine, Kroemer, Guido, Lacas‐Gervais, Sandra, Tran, Albert, Gual, Philippe, Bailly‐Maitre, Béatrice

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Autophagy is required for CSF-1–induced macrophagic differentiation and acquisition of phagocytic functions von Jacquel, Arnaud, Obba, Sandrine, Boyer, Laurent, Dufies, Maeva, Robert, Guillaume, Gounon, Pierre, Lemichez, Emmanuel, Luciano, Frederic, Solary, Eric, Auberger, Patrick

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SYK Is a Critical Regulator of FLT3 in Acute Myeloid Leukemia von Puissant, Alexandre, Fenouille, Nina, Alexe, Gabriela, Pikman, Yana, Bassil, Christopher F., Mehta, Swapnil, Du, Jinyan, Kazi, Julhash U., Luciano, Frédéric, Rönnstrand, Lars, Kung, Andrew L., Aster, Jon C., Galinsky, Ilene, Stone, Richard M., DeAngelo, Daniel J., Hemann, Michael T., Stegmaier, Kimberly

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The protective effect of phorbol esters on Fas-mediated apoptosis in T cells. Transcriptional and postranscriptional regulation von HERRANT, Magali, LUCIANO, Frédéric, LOUBAT, Agnès, AUBERGER, Patrick

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Reconstituted NALP1 Inflammasome Reveals Two-Step Mechanism of Caspase-1 Activation von Faustin, Benjamin, Lartigue, Lydia, Bruey, Jean-Marie, Luciano, Frederic, Sergienko, Eduard, Bailly-Maitre, Beatrice, Volkmann, Niels, Hanein, Dorit, Rouiller, Isabelle, Reed, John C.

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Autophagy is an important event for megakaryocytic differentiation of the chronic myelogenous leukemia K562 cell line von Colosetti, Pascal, Puissant, Alexandre, Robert, Guillaume, Luciano, Fréderic, Jacquel, Arnaud, Gounon, Pierre, Cassuto, Jill-Patrice, Auberger, Patrick

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Dual Covalent Inhibition of PKM and IMPDH Targets Metabolism in Cutaneous Metastatic Melanoma von Zerhouni, Marwa, Martin, Anthony R., Furstoss, Nathan, Gutierrez, Vincent S., Jaune, Emilie, Tekaya, Nedra, Beranger, Guillaume E., Abbe, Patricia, Regazzetti, Claire, Amdouni, Hella, Driowya, Mohsine, Dubreuil, Patrice, Luciano, Frederic, Jacquel, Arnaud, Tulic, Meri K., Cluzeau, Thomas, O'Hara, Brendan P., Ben-Sahra, Issam, Passeron, Thierry, Benhida, Rachid, Robert, Guillaume, Auberger, Patrick, Rocchi, Stephane

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Caspase 1/11 Deficiency or Pharmacological Inhibition Mitigates Psoriasis-Like Phenotype in Mice von Aira, Lazaro Emilio, Gonçalves, Diogo, Bossowski, Jozef P., Rubio-Patiño, Camila, Chiche, Johanna, Paul-Bellon, Rachel, Mondragón, Laura, Gesson, Maéva, Lecucq-Ottavi, Priscillia, Obba, Sandrine, Colosetti, Pascal, Luciano, Frédéric, Bailly-Maitre, Béatrice, Boyer, Laurent, Jacquel, Arnaud, Robert, Guillaume, Ricci, Jean-Ehrland, Ortonne, Jean-Paul, Passeron, Thierry, Lacour, Jean-Philippe, Auberger, Patrick, Marchetti, Sandrine

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The oncogenic tyrosine kinase Lyn impairs the pro-apoptotic function of Bim von Aira, Lazaro E., Villa, Elodie, Colosetti, Pascal, Gamas, Parvati, Signetti, Laurie, Obba, Sandrine, Proics, Emma, Gautier, Fabien, Bailly-Maitre, Béatrice, Jacquel, Arnaud, Robert, Guillaume, Luciano, Frédéric, Juin, Philippe P., Ricci, Jean-Ehrland, Auberger, Patrick, Marchetti, Sandrine

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Cytoprotective Gene bi-1 Is Required for Intrinsic Protection from Endoplasmic Reticulum Stress and Ischemia-Reperfusion Injury von Bailly-Maitre, Béatrice, Fondevila, Constantino, Kaldas, Fady, Droin, Nathalie, Luciano, Fréderic, Ricci, Jean-Ehrland, Croxton, Rhonda, Krajewska, Maryla, Zapata, Juan M., Kupiec-Weglinski, Jerzy W., Farmer, Douglas, Reed, John C.

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Opposing Roles of Vascular Endothelial Growth Factor C in Metastatic Dissemination and Resistance to Radio/Chemotherapy: Discussion of Mechanisms and Therapeutic Strategies von Montemagno, Christopher, Luciano, Frédéric, Pagès, Gilles

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