CD45 Phosphatase Inhibits STAT3 Transcription Factor Activity in Myeloid Cells and Promotes Tumor-Associated Macrophage Differentiation von Kumar, Vinit, Cheng, Pingyan, Condamine, Thomas, Mony, Sridevi, Languino, Lucia R., McCaffrey, Judith C., Hockstein, Neil, Guarino, Michael, Masters, Gregory, Penman, Emily, Denstman, Fred, Xu, Xiaowei, Altieri, Dario C., Du, Hong, Yan, Cong, Gabrilovich, Dmitry I.

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The Mitochondrial Unfoldase-Peptidase Complex ClpXP Controls Bioenergetics Stress and Metastasis von Seo, Jae Ho, Rivadeneira, Dayana B, Caino, M Cecilia, Chae, Young Chan, Speicher, David W, Tang, Hsin-Yao, Vaira, Valentina, Bosari, Silvano, Palleschi, Alessandro, Rampini, Paolo, Kossenkov, Andrew V, Languino, Lucia R, Altieri, Dario C

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PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion von Caino, M. Cecilia, Jagadish C. Ghosh, Young Chan Chae, Valentina Vaira, Dayana B. Rivadeneira, Alice Faversani, Paolo Rampini, Andrew V. Kossenkov, Katherine M. Aird, Rugang Zhang, Marie R. Webster, Ashani T. Weeraratna, Silvano Bosari, Lucia R. Languino, Dario C. Altieri

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Identification of monocyte-like precursors of granulocytes in cancer as a mechanism for accumulation of PMN-MDSCs von Mastio, Jérôme, Condamine, Thomas, Dominguez, George, Kossenkov, Andrew V, Donthireddy, Laxminarasimha, Veglia, Filippo, Lin, Cindy, Wang, Fang, Fu, Shuyu, Zhou, Jie, Viatour, Patrick, Lavilla-Alonso, Sergio, Polo, Alexander T, Tcyganov, Evgenii N, Mulligan, Jr, Charles, Nam, Brian, Bennett, Joseph, Masters, Gregory, Guarino, Michael, Kumar, Amit, Nefedova, Yulia, Vonderheide, Robert H, Languino, Lucia R, Abrams, Scott I, Gabrilovich, Dmitry I

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A neuronal network of mitochondrial dynamics regulates metastasis von Caino, M. Cecilia, Seo, Jae Ho, Aguinaldo, Angeline, Wait, Eric, Bryant, Kelly G., Kossenkov, Andrew V., Hayden, James E., Vaira, Valentina, Morotti, Annamaria, Ferrero, Stefano, Bosari, Silvano, Gabrilovich, Dmitry I., Languino, Lucia R., Cohen, Andrew R., Altieri, Dario C.

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Small Extracellular Vesicle Regulation of Mitochondrial Dynamics Reprograms a Hypoxic Tumor Microenvironment von Bertolini, Irene, Ghosh, Jagadish C., Kossenkov, Andrew V., Mulugu, Sudheer, Krishn, Shiv Ram, Vaira, Valentina, Qin, Jun, Plow, Edward F., Languino, Lucia R., Altieri, Dario C.

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Control of Tumor Bioenergetics and Survival Stress Signaling by Mitochondrial HSP90s von Chae, Young Chan, Caino, M. Cecilia, Lisanti, Sofia, Ghosh, Jagadish C., Dohi, Takehiko, Danial, Nika N., Villanueva, Jessie, Ferrero, Stefano, Vaira, Valentina, Santambrogio, Luigi, Bosari, Silvano, Languino, Lucia R., Herlyn, Meenhard, Altieri, Dario C.

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Survivin promotes oxidative phosphorylation, subcellular mitochondrial repositioning, and tumor cell invasion von Rivadeneira, Dayana B, Caino, M Cecilia, Seo, Jae Ho, Angelin, Alessia, Wallace, Douglas C, Languino, Lucia R, Altieri, Dario C

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MFF Regulation of Mitochondrial Cell Death Is a Therapeutic Target in Cancer von Seo, Jae Ho, Chae, Young Chan, Kossenkov, Andrew V, Lee, Yu Geon, Tang, Hsin-Yao, Agarwal, Ekta, Gabrilovich, Dmitry I, Languino, Lucia R, Speicher, David W, Shastrula, Prashanth K, Storaci, Alessandra Maria, Ferrero, Stefano, Gaudioso, Gabriella, Caroli, Manuela, Tosi, Davide, Giroda, Massimo, Vaira, Valentina, Rebecca, Vito W, Herlyn, Meenhard, Xiao, Min, Fingerman, Dylan, Martorella, Alessandra, Skordalakes, Emmanuel, Altieri, Dario C

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Small extracellular vesicle-mediated ITGB6 siRNA delivery downregulates the αVβ6 integrin and inhibits adhesion and migration of recipient prostate cancer cells von Krishn, Shiv Ram, Garcia, Vaughn, Naranjo, Nicole M., Quaglia, Fabio, Shields, Christopher D., Harris, Maisha A., Kossenkov, Andrew V., Liu, Qin, Corey, Eva, Altieri, Dario C., Languino, Lucia R.

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Role of Kindlin 2 in prostate cancer von Bialkowska, Katarzyna, El Khalki, Lamyae, Rana, Priyanka S., Wang, Wei, Lindner, Daniel J., Parker, Yvonne, Languino, Lucia R., Altieri, Dario C., Pluskota, Elzbieta, Sossey-Alaoui, Khalid, Plow, Edward F.

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Myc-mediated transcriptional regulation of the mitochondrial chaperone TRAP1 controls primary and metastatic tumor growth von Agarwal, Ekta, Altman, Brian J., Seo, Jae Ho, Ghosh, Jagadish C., Kossenkov, Andrew V., Tang, Hsin-Yao, Krishn, Shiv Ram, Languino, Lucia R., Gabrilovich, Dmitry I., Speicher, David W., Dang, Chi V., Altieri, Dario C.

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Integrins in prostate cancer progression von Goel, Hira Lal, Li, Jing, Kogan, Sophia, Languino, Lucia R

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Myc Regulation of a Mitochondrial Trafficking Network Mediates Tumor Cell Invasion and Metastasis von Agarwal, Ekta, Altman, Brian J., Ho Seo, Jae, Bertolini, Irene, Ghosh, Jagadish C., Kaur, Amanpreet, Kossenkov, Andrew V., Languino, Lucia R., Gabrilovich, Dmitry I., Speicher, David W., Dang, Chi V., Altieri, Dario C.

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Deletion of the Mitochondrial Chaperone TRAP-1 Uncovers Global Reprogramming of Metabolic Networks von Lisanti, Sofia, Tavecchio, Michele, Chae, Young Chan, Liu, Qin, Brice, Angela K., Thakur, Madhukar L., Languino, Lucia R., Altieri, Dario C.

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Trop-2 inhibits prostate cancer cell adhesion to fibronectin through the β1 integrin-RACK1 axis von Trerotola, Marco, Li, Jing, Alberti, Saverio, Languino, Lucia R.

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Neuroendocrine gene subsets are uniquely dysregulated in prostate adenocarcinoma von Naranjo, Nicole M, Kennedy, Anne, Testa, Anna, Verrillo, Cecilia E, Altieri, Adrian D, Kean, Rhonda, Hooper, D Craig, Yu, Jindan, Zhao, Jonathan, Abinader, Oliver, Pickles, Maxwell W, Hawkins, Adam, Kelly, William K, Mitra, Ramkrishna, Languino, Lucia R

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IGF-IR promotes prostate cancer growth by stabilizing α5β1 integrin protein levels von Sayeed, Aejaz, Fedele, Carmine, Trerotola, Marco, Ganguly, Kirat K, Languino, Lucia R

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The Runx2 Osteogenic Transcription Factor Regulates Matrix Metalloproteinase 9 in Bone Metastatic Cancer Cells and Controls Cell Invasion von Pratap, Jitesh, Javed, Amjad, Languino, Lucia R., van Wijnen, Andre J., Stein, Janet L., Stein, Gary S., Lian, Jane B.

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αvβ6 integrin is required for TGFβ1-mediated matrix metalloproteinase2 expression von Dutta, Anindita, Li, Jing, Fedele, Carmine, Sayeed, Aejaz, Singh, Amrita, Violette, Shelia M, Manes, Thomas D, Languino, Lucia R

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