Protocol to create isogenic disease models from adult stem cell-derived organoids using next-generation CRISPR tools von Celotti, Martina, Derks, Lucca L.M., van Es, Johan, van Boxtel, Ruben, Clevers, Hans, Geurts, Maarten H.

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Protocol for genome-wide analysis of somatic variants at single-cell resolution using primary template-directed DNA amplification von Derks, Lucca L.M., van Leeuwen, Anaïs J.C.N., Steemers, Alexander S., Trabut, Laurianne, van Roosmalen, Markus J., Poort, Vera M., Hagelaar, Rico, Verheul, Mark, Middelkamp, Sjors, van Boxtel, Ruben

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Stem cell mutations, associated cancer risk, and consequences for regenerative medicine von Derks, Lucca L.M., van Boxtel, Ruben

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One-step generation of tumor models by base editor multiplexing in adult stem cell-derived organoids von Geurts, Maarten H., Gandhi, Shashank, Boretto, Matteo G., Akkerman, Ninouk, Derks, Lucca L. M., van Son, Gijs, Celotti, Martina, Harshuk-Shabso, Sarina, Peci, Flavia, Begthel, Harry, Hendriks, Delilah, Schürmann, Paul, Andersson-Rolf, Amanda, Chuva de Sousa Lopes, Susana M., van Es, Johan H., van Boxtel, Ruben, Clevers, Hans

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Single-Cell Whole-Genome Sequencing after Chemotherapeutic Treatment Reveals Cell Type-Specific Mutational Burdens von Derks, Lucca L.M., Van Der Werf, Inge, Trabut, Laurianne, Bertrums, Eline, De Kanter, Jurrian, Rosendahl Huber, Axel, Van Boxtel, Ruben

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Efficient and error-free fluorescent gene tagging in human organoids without double-strand DNA cleavage von Bollen, Yannik, Hageman, Joris H, van Leenen, Petra, Derks, Lucca L M, Ponsioen, Bas, Buissant des Amorie, Julian R, Verlaan-Klink, Ingrid, van den Bos, Myrna, Terstappen, Leon W M M, van Boxtel, Ruben, Snippert, Hugo J G

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Cell division‐dependent dissemination following E‐cadherin loss underlies initiation of diffuse‐type gastric cancer von Monster, Jooske L, Kemp, Lars JS, Busslinger, Georg A, Vliem, Marjolein J, Derks, Lucca LM, Staes, Annelot AL, Bisseling, Tanya M, Clevers, Hans, Post, Rachel S, Gloerich, Martijn

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Protocol to create isogenic disease models from adult stem cell-derived organoids using next-generation CRISPR tools von Celotti, Martina, Derks, Lucca L.M, van Es, Johan, van Boxtel, Ruben, Clevers, Hans, Geurts, Maarten H

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One-step generation of tumor models by base editor multiplexing in adult stem cell-derived organoids von Geurts, Maarten H, Gandhi, Shashank, Boretto, Matteo G, Akkerman, Ninouk, Derks, Lucca L.M, van Son, Gijs, Celotti, Martina, Harshuk-Shabso, Sarina, Peci, Flavia, Begthel, Harry, Hendriks, Delilah, Schürmann, Paul, Andersson-Rolf, Amanda, Chuva de Sousa Lopes, Susana M, van Es, Johan H, van Boxtel, Ruben, Clevers, Hans

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Comprehensive single-cell genome analysis at nucleotide resolution using the PTA Analysis Toolbox von Middelkamp, Sjors, Manders, Freek, Peci, Flavia, van Roosmalen, Markus J., González, Diego Montiel, Bertrums, Eline J.M., van der Werf, Inge, Derks, Lucca L.M., Groenen, Niels M., Verheul, Mark, Trabut, Laurianne, Pleguezuelos-Manzano, Cayetano, Brandsma, Arianne M., Antoniou, Evangelia, Reinhardt, Dirk, Bierings, Marc, Belderbos, Mirjam E., van Boxtel, Ruben

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Comprehensive single-cell genome analysis at nucleotide resolution using the PTA Analysis Toolbox von Middelkamp, Sjors, Manders, Freek, Peci, Flavia, van Roosmalen, Markus J, González, Diego Montiel, Bertrums, Eline J.M, van der Werf, Inge, Derks, Lucca L.M, Groenen, Niels M, Verheul, Mark, Trabut, Laurianne, Pleguezuelos-Manzano, Cayetano, Brandsma, Arianne M, Antoniou, Evangelia, Reinhardt, Dirk, Bierings, Marc, Belderbos, Mirjam E, van Boxtel, Ruben

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