Genomic Landscape of Atypical Adenomatous Hyperplasia Reveals Divergent Modes to Lung Adenocarcinoma von Sivakumar, Smruthy, Lucas, F Anthony San, McDowell, Tina L, Lang, Wenhua, Xu, Li, Fujimoto, Junya, Zhang, Jianjun, Futreal, P Andrew, Fukuoka, Junya, Yatabe, Yasushi, Dubinett, Steven M, Spira, Avrum E, Fowler, Jerry, Hawk, Ernest T, Wistuba, Ignacio I, Scheet, Paul, Kadara, Humam

Volltext

Single-Cell Transcriptomics of Pancreatic Cancer Precursors Demonstrates Epithelial and Microenvironmental Heterogeneity as an Early Event in Neoplastic Progression von Bernard, Vincent, Semaan, Alexander, Huang, Jonathan, San Lucas, F Anthony, Mulu, Feven C, Stephens, Bret M, Guerrero, Paola A, Huang, Yanqing, Zhao, Jun, Kamyabi, Nabiollah, Sen, Subrata, Scheet, Paul A, Taniguchi, Cullen M, Kim, Michael P, Tzeng, Ching-Wei, Katz, Matthew H, Singhi, Aatur D, Maitra, Anirban, Alvarez, Hector A

Volltext

Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism von Zhao, Hongyun, Yang, Lifeng, Baddour, Joelle, Achreja, Abhinav, Bernard, Vincent, Moss, Tyler, Marini, Juan C, Tudawe, Thavisha, Seviour, Elena G, San Lucas, F Anthony, Alvarez, Hector, Gupta, Sonal, Maiti, Sourindra N, Cooper, Laurence, Peehl, Donna, Ram, Prahlad T, Maitra, Anirban, Nagrath, Deepak

Volltext

A Visually Apparent and Quantifiable CT Imaging Feature Identifies Biophysical Subtypes of Pancreatic Ductal Adenocarcinoma von Koay, Eugene J, Lee, Yeonju, Cristini, Vittorio, Lowengrub, John S, Kang, Ya'an, Lucas, F Anthony San, Hobbs, Brian P, Ye, Rong, Elganainy, Dalia, Almahariq, Muayad, Amer, Ahmed M, Chatterjee, Deyali, Yan, Huaming, Park, Peter C, Rios Perez, Mayrim V, Li, Dali, Garg, Naveen, Reiss, Kim A, Yu, Shun, Chauhan, Anil, Zaid, Mohamed, Nikzad, Newsha, Wolff, Robert A, Javle, Milind, Varadhachary, Gauri R, Shroff, Rachna T, Das, Prajnan, Lee, Jeffrey E, Ferrari, Mauro, Maitra, Anirban, Taniguchi, Cullen M, Kim, Michael P, Crane, Christopher H, Katz, Matthew H, Wang, Huamin, Bhosale, Priya, Tamm, Eric P, Fleming, Jason B

Volltext

DNA Sequencing of Small Bowel Adenocarcinomas Identifies Targetable Recurrent Mutations in the ERBB2 Signaling Pathway von Adam, Liana, San Lucas, F Anthony, Fowler, Richard, Yu, Yao, Wu, Wenhui, Liu, Yulun, Wang, Huamin, Menter, David, Tetzlaff, Michael T, Ensor, Jr, Joe, Manyam, Ganiraju, Arold, Stefan T, Huff, Chad, Kopetz, Scott, Scheet, Paul, Overman, Michael J

Volltext

Genetic risk factors for the development of osteonecrosis in children under age 10 treated for acute lymphoblastic leukemia von Karol, Seth E., Mattano, Leonard A., Yang, Wenjian, Maloney, Kelly W., Smith, Colton, Liu, ChengCheng, Ramsey, Laura B., Fernandez, Christian A., Chang, Tamara Y., Neale, Geoffrey, Cheng, Cheng, Mardis, Elaine, Fulton, Robert, Scheet, Paul, San Lucas, F. Anthony, Larsen, Eric C., Loh, Mignon L., Raetz, Elizabeth A., Hunger, Stephen P., Devidas, Meenakshi, Relling, Mary V.

Volltext

Strategies for identification of somatic variants using the Ion Torrent deep targeted sequencing platform von Deshpande, Aditya, Lang, Wenhua, McDowell, Tina, Sivakumar, Smruthy, Zhang, Jiexin, Wang, Jing, San Lucas, F Anthony, Fowler, Jerry, Kadara, Humam, Scheet, Paul

Volltext

Genomic Landscape of Colorectal Mucosa and Adenomas von Borras, Ester, San Lucas, F Anthony, Chang, Kyle, Zhou, Ruoji, Masand, Gita, Fowler, Jerry, Mork, Maureen E, You, Y Nancy, Taggart, Melissa W, McAllister, Florencia, Jones, David A, Davies, Gareth E, Edelmann, Winfried, Ehli, Erik A, Lynch, Patrick M, Hawk, Ernest T, Capella, Gabriel, Scheet, Paul, Vilar, Eduardo

Volltext

Mutational Heterogeneity in APC and KRAS Arises at the Crypt Level and Leads to Polyclonality in Early Colorectal Tumorigenesis von Gausachs, Mireia, Borras, Ester, Chang, Kyle, Gonzalez, Sara, Azuara, Daniel, Delgado Amador, Axel, Lopez-Doriga, Adriana, San Lucas, F Anthony, Sanjuan, Xavier, Paules, Maria J, Taggart, Melissa W, Davies, Gareth E, Ehli, Erik A, Fowler, Jerry, Moreno, Victor, Pineda, Marta, You, Y Nancy, Lynch, Patrick M, Lazaro, Conxi, Navin, Nicholas E, Scheet, Paul A, Hawk, Ernest T, Capella, Gabriel, Vilar, Eduardo

Volltext

Incorporating prior knowledge into Gene Network Study von Wang, Zixing, Xu, Wenlong, San Lucas, F Anthony, Liu, Yin

Volltext

Pan cancer patterns of allelic imbalance from chromosomal alterations in 33 tumor types von Sivakumar, Smruthy, San Lucas, F Anthony, Jakubek, Yasminka A, Ozcan, Zuhal, Fowler, Jerry, Scheet, Paul

Volltext

Mitochondrial fusion exploits a therapeutic vulnerability of pancreatic cancer von Yu, Meifang, Nguyen, Nicholas D, Huang, Yanqing, Lin, Daniel, Fujimoto, Tara N, Molkentine, Jessica M, Deorukhkar, Amit, Kang, Ya'an, San Lucas, F Anthony, Fernandes, Conrad J, Koay, Eugene J, Gupta, Sonal, Ying, Haoqiang, Koong, Albert C, Herman, Joseph M, Fleming, Jason B, Maitra, Anirban, Taniguchi, Cullen M

Volltext

Driver Mutations in Normal Airway Epithelium Elucidate Spatiotemporal Resolution of Lung Cancer von Kadara, Humam, Sivakumar, Smruthy, Jakubek, Yasminka, San Lucas, F Anthony, Lang, Wenhua, McDowell, Tina, Weber, Zachary, Behrens, Carmen, Davies, Gareth E, Kalhor, Neda, Moran, Cesar, El-Zein, Randa, Mehran, Reza, Swisher, Stephen G, Wang, Jing, Zhang, Jianjun, Fujimoto, Junya, Fowler, Jerry, Heymach, John V, Dubinett, Steven, Spira, Avrum E, Ehli, Erik A, Wistuba, Ignacio I, Scheet, Paul

Volltext

Rapid and powerful detection of subtle allelic imbalance from exome sequencing data with hapLOHseq von San Lucas, F Anthony, Sivakumar, Smruthy, Vattathil, Selina, Fowler, Jerry, Vilar, Eduardo, Scheet, Paul

Volltext

Preliminary whole-exome sequencing reveals mutations that imply common tumorigenicity pathways in multiple endocrine neoplasia type 1 patients von Romero Arenas, Minerva Angélica, MD, MPH, Fowler, Richard G., PhD, San Lucas, F. Anthony, MS, Shen, Jie, PhD, Rich, Thereasa A., MS, Grubbs, Elizabeth G., MD, Lee, Jeffrey E., MD, Scheet, Paul, PhD, Perrier, Nancy D., MD, Zhao, Hua, PhD

Volltext

Improving the sensitivity of sample clustering by leveraging gene co-expression networks in variable selection von Wang, Zixing, San Lucas, F Anthony, Qiu, Peng, Liu, Yin

Volltext

Assessing inter-component heterogeneity of biphasic uterine carcinosarcomas von Liu, Yihua, Weber, Zachary, San Lucas, F. Anthony, Deshpande, Aditya, Jakubek, Yasminka A., Sulaiman, Raed, Fagerness, Mary, Flier, Natasha, Sulaiman, Joseph, Davis, Christel M., Fowler, Jerry, Starks, David, Rojas-Espaillat, Luis, Lazar, Alexander J., Davies, Gareth E., Ehli, Erik A., Scheet, Paul

Volltext

Cancer in silico drug discovery: a systems biology tool for identifying candidate drugs to target specific molecular tumor subtypes von San Lucas, F Anthony, Fowler, Jerry, Chang, Kyle, Kopetz, Scott, Vilar, Eduardo, Scheet, Paul

Volltext

HIF2 Regulates Intestinal Wnt5a Expression von Garcia Garcia, Carolina J., Acevedo Diaz, Ariana C., Kumari, Neeraj, Govindaraju, Suman, de la Cruz Bonilla, Marimar, San Lucas, F. Anthony, Nguyen, Nicholas D., Jimenez Sacarello, Iancarlos, Piwnica-Worms, Helen, Maitra, Anirban, Taniguchi, Cullen M.

Volltext

Circulating Nucleic Acids Are Associated With Outcomes of Patients With Pancreatic Cancer von Bernard, Vincent, Kim, Dong U., San Lucas, F. Anthony, Castillo, Jonathan, Allenson, Kelvin, Mulu, Feven C., Stephens, Bret M., Huang, Jonathan, Semaan, Alexander, Guerrero, Paola A., Kamyabi, Nabiollah, Zhao, Jun, Hurd, Mark W., Koay, Eugene J., Taniguchi, Cullen M., Herman, Joseph M., Javle, Milind, Wolff, Robert, Katz, Matthew, Varadhachary, Gauri, Maitra, Anirban, Alvarez, Hector A.

Volltext