Efficient gene silencing by delivery of locked nucleic acid antisense oligonucleotides, unassisted by transfection reagents von Stein, C.A, Hansen, J. Bo, Lai, Johnathan, Wu, SiJian, Voskresenskiy, Anatoliy, Høg, Anja, Worm, Jesper, Hedtjärn, Maj, Souleimanian, Naira, Miller, Paul, Soifer, Harris S, Castanotto, Daniella, Benimetskaya, Luba, Ørum, Henrik, Koch, Troels

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A Pharmacologic Target of G3139 in Melanoma Cells May Be the Mitochondrial VDAC von Lai, Johnathan C., Tan, Wenzhi, Benimetskaya, Luba, Miller, Paul, Colombini, Marco, Stein, C. A.

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Angiogenesis alteration by defibrotide: implications for its mechanism of action in severe hepatic veno-occlusive disease von Benimetskaya, Luba, Wu, Sijian, Voskresenskiy, Anatoliy M., Echart, Cinara, Zhou, Jin-Feng, Shin, Joongho, Iacobelli, Massimo, Richardson, Paul, Ayyanar, Kanyalakshmi, Stein, C.A.

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G3139, an Anti-Bcl-2 Antisense Oligomer That Binds Heparin-Binding Growth Factors and Collagen I, Alters In vitro Endothelial Cell Growth and Tubular Morphogenesis von STEIN, C. A, SIJIAN WU, VOSKRESENSKIY, Anatoliy M, ZHOU, Jin-Feng, SHIN, Joongho, MILLER, Paul, SOULEIMANIAN, Naira, BENIMETSKAYA, Luba

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Antisense RNA Down-Regulation of bcl-2 Expression in DU145 Prostate Cancer Cells Does Not Diminish the Cytostatic Effects of G3139 (Oblimersen) von RAFFO, Anthony, LAI, Johnathan C, STEIN, C. A, MILLER, Paul, SCARINGE, Steven, KHVOROVA, Anastasia, BENIMETSKAYA, Luba

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G3139 (oblimersen) may inhibit prostate cancer cell growth in a partially bis-CpG-dependent non-antisense manner von Lai, Jonathan C, Benimetskaya, Luba, Santella, Regina M, Wang, Qiao, Miller, Paul S, Stein, C A

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Phosphorothioate oligodeoxynucleotides and G3139 induce apoptosis in 518A2 melanoma cells von Lai, Johnathan C, Benimetskaya, Luba, Khvorova, Anastasia, Wu, Sijian, Hua, Emily, Miller, Paul, Stein, C A

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Bcl-2 Protein in 518A2 Melanoma Cells In vivo and In vitro von BENIMETSKAYA, Luba, AYYANAR, Kanyalakshmi, MCMICKEN, Harilyn, YIN CHEN, STEIN, C. A, KORNBLUM, Noah, CASTANOTTO, Daniela, ROSSI, John, SIJIAN WU, LAI, Johnathan, BROWN, Bob D, POPOVA, Natalia, MILLER, Paul

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Relative Bcl-2 Independence of Drug-Induced Cytotoxicity and Resistance in 518A2 Melanoma Cells von BENIMETSKAYA, Luba, LAI, Johnathan C, KHVOROVA, Anastasia, SIJIAN WU, HUA, Emily, MILLER, Paul, ZHANG, Li-Ming, STEIN, Cy A

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Changes in Gene Expression Induced by Phosphorothioate Oligodeoxynucleotides (Including G3139) in PC3 Prostate Carcinoma Cells Are Recapitulated at Least in Part by Treatment with... von BENIMETSKAYA, Luba, WITTENBERGER, Timo, STEIN, C. A, HOFMANN, Hans-Peter, WELLER, Claudia, LAI, Johnathan C, MILLERS, Paul, GEKELER, Volker

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Antisense Strategies for Oncogene Inactivation von Stein, C.A., Benimetskaya, Luba, Mani, S.

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Inhibition of Potentially Anti-Apoptotic Proteins by Antisense Protein Kinase C-α (Isis 3521) and Antisense bcl-2 (G3139) Phosphorothioate Oligodeoxynucleotides: Relationship to th... von Benimetskaya, Luba, Miller, Paul, Benimetsky, Simon, Maciaszek, Anna, Guga, Piotr, Beaucage, Serge L., Wilk, Andrzej, Grajkowski, Andrzej, Halperin, Anthony L., Stein, C.A.

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Delivery of G3139 using releasable PEG-linkers: Impact on pharmacokinetic profile and anti-tumor efficacy von Zhao, Hong, Peng, Ping, Longley, Clifford, Zhang, Yue, Borowski, Virna, Mehlig, Mary, Reddy, Prasanna, Xia, Jing, Borchard, Gerrit, Lipman, Jack, Benimetskaya, Luba, Stein, C.A.

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Antisense RNA down-regulation of bcl-xL expression in prostate cancer cells leads to diminished rates of cellular proliferation and resistance to cytotoxic chemotherapeutic agents von VILENCHIK, Maria, RAFFO, Anthony J, BENIMETSKAYA, Luba, SHAMES, David, STEIN, C. A

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Inhibition of Bcl-2 by Anti-Sense Oligonucleotide and siRNA in Specimens from Patients with Waldenström’s Macroglobulinemia (WM) von Nichols, Gwen L., Benimetskaya, Luba, Stein, Cy A.

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Inhibition of Bcl-2 by Anti-Sense Oligonucleotide and siRNA in Specimens from Patients with Waldenström's Macroglobulinemia (WM) von Nichols, Gwen L., Benimetskaya, Luba, Stein, Cy A.

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Angiogenesis alteration by defibrotide : implications for its mechanism of action in severe hepatic veno-occlusive disease. Commentary von LAZARUS, Hillard M, MCCRAE, Keith R, AYYANAR, Kanyalakshmi, STEIN, C. A, BENIMETSKAYA, Luba, SIJIAN WU, VOSKRESENSKIY, Anatoliy M, ECHART, Cinara, ZHOU, Jin-Feng, SHIN, Joongho, IACOBELLI, Massimo, RICHARDSON, Paul

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Comparison of D-G3139 and Its Enantiomer L-G3139 in Melanoma Cells Demonstrates Minimal In Vitro but Dramatic In Vivo Chiral Dependency von Lai, Johnathan C, Brown, Bob D, Voskresenskiy, Anatoliy M, Vonhoff, Stefan, Klussman, Sven, Tan, Wenzhi, Colombini, Marco, Weeratna, Risini, Miller, Paul, Benimetskaya, Luba, Stein, Cy A

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Defibrotide (DF), an Orally Bioavailable Modulator of Myeloma Tumor-Microenvironment Interactions: Molecular Sequelae and Clinical Implications von Mitsiades, Constantine S., Benimetskaya, Luba, Menon, Krishna, Echart, Cinara, Rouleau, Cecile, Teicher, Beverly, Palumbo, Antonio, Boccadoro, Mario, Iacobelli, Massimo, Anderson, Kenneth C., Stein, Cy A., Richardson, Paul G.

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Induction of Apoptosis by G3139 in Melanoma Cells von BENIMETSKAYA, LUBA, LAI, JOHNATHAN C., KHVOROVA, ANASTASIA, WU, SIJIAN, MILLER, PAUL, STEIN, C A

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