Ergot alkaloids. Synthesis of nitrosourea derivatives of ergolines as potential anticancer agents von Crider, A. Michael, Lu, Catherine K. L, Floss, Heinz G, Cassady, John M, Clemens, James A

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De novo emergence of a remdesivir resistance mutation during treatment of persistent SARS-CoV-2 infection in an immunocompromised patient: a case report von Gandhi, Shiv, Klein, Jonathan, Robertson, Alexander J., Peña-Hernández, Mario A., Lin, Michelle J., Roychoudhury, Pavitra, Lu, Peiwen, Fournier, John, Ferguson, David, Mohamed Bakhash, Shah A. K., Catherine Muenker, M., Srivathsan, Ariktha, Wunder, Elsio A., Kerantzas, Nicholas, Wang, Wenshuai, Lindenbach, Brett, Pyle, Anna, Wilen, Craig B., Ogbuagu, Onyema, Greninger, Alexander L., Iwasaki, Akiko, Schulz, Wade L., Ko, Albert I.

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Oncogenic KRAS Reduces Expression of FGF21 in Acinar Cells to Promote Pancreatic Tumorigenesis in Mice on a High-Fat Diet von Luo, Yongde, Yang, Yaying, Liu, Muyun, Wang, Dan, Wang, Feng, Bi, Yawei, Ji, Juntao, Li, Suyun, Liu, Yan, Chen, Rong, Huang, Haojie, Wang, Xiaojie, Swidnicka-Siergiejko, Agnieszka K., Janowitz, Tobias, Beyaz, Semir, Wang, Guoqiang, Xu, Sulan, Bialkowska, Agnieszka B., Luo, Catherine K., Pin, Christoph L., Liang, Guang, Lu, Xiongbin, Wu, Maoxin, Shroyer, Kenneth R., Wolff, Robert A., Plunkett, William, Ji, Baoan, Li, Zhaoshen, Li, Ellen, Li, Xiaokun, Yang, Vincent W., Logsdon, Craig D., Abbruzzese, James L., Lu, Weiqin

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Local and systemic responses to SARS-CoV-2 infection in children and adults von Yoshida, Masahiro, Worlock, Kaylee B., Huang, Ni, Lindeboom, Rik G. H., Butler, Colin R., Kumasaka, Natsuhiko, Dominguez Conde, Cecilia, Mamanova, Lira, Bolt, Liam, Richardson, Laura, Polanski, Krzysztof, Madissoon, Elo, Barnes, Josephine L., Allen-Hyttinen, Jessica, Kilich, Eliz, Jones, Brendan C., de Wilton, Angus, Wilbrey-Clark, Anna, Sungnak, Waradon, Pett, J. Patrick, Weller, Juliane, Prigmore, Elena, Yung, Henry, Mehta, Puja, Saleh, Aarash, Saigal, Anita, Chu, Vivian, Cohen, Jonathan M., Cane, Clare, Iordanidou, Aikaterini, Shibuya, Soichi, Reuschl, Ann-Kathrin, Herczeg, Iván T., Argento, A. Christine, Wunderink, Richard G., Smith, Sean B., Poor, Taylor A., Gao, Catherine A., Dematte, Jane E., Reynolds, Gary, Haniffa, Muzlifah, Bowyer, Georgina S., Coates, Matthew, Clatworthy, Menna R., Calero-Nieto, Fernando J., Göttgens, Berthold, O’Callaghan, Christopher, Sebire, Neil J., Jolly, Clare, De Coppi, Paolo, Smith, Claire M., Misharin, Alexander V., Janes, Sam M., Teichmann, Sarah A., Nikolić, Marko Z., Meyer, Kerstin B.

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Afatinib versus gefitinib as first-line treatment of patients with EGFR mutation-positive non-small-cell lung cancer (LUX-Lung 7): a phase 2B, open-label, randomised controlled tri... von Park, Keunchil, Prof, Tan, Eng-Huat, MD, O'Byrne, Ken, Prof, Zhang, Li, Prof, Boyer, Michael, Prof, Mok, Tony, Prof, Hirsh, Vera, Prof, Yang, James Chih-Hsin, Prof, Lee, Ki Hyeong, MD, Lu, Shun, Prof, Shi, Yuankai, MD, Kim, Sang-We, MD, Laskin, Janessa, MD, Kim, Dong-Wan, Prof, Arvis, Catherine Dubos, MD, Kölbeck, Karl, MD, Laurie, Scott A, MD, Tsai, Chun-Ming, Prof, Shahidi, Mehdi, MD, Kim, Miyoung, MD, Massey, Dan, PhD, Zazulina, Victoria, MD, Paz-Ares, Luis, MD

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The prognostic significance of IDH2 mutations in AML depends on the location of the mutation von Green, Claire L., Evans, Catherine M., Zhao, Lu, Hills, Robert K., Burnett, Alan K., Linch, David C., Gale, Rosemary E.

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Metabolic mediators of the effects of body-mass index, overweight, and obesity on coronary heart disease and stroke: a pooled analysis of 97 prospective cohorts with 1·8 million pa... von YUAN LU, HAJIFATHALIAN, Kaveh, EZZATI, Majid, WOODWARD, Mark, RIMM, Eric B, DANAEI, Goodarz

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IFN-γ-independent immune markers of Mycobacterium tuberculosis exposure von Lu, Lenette L., Smith, Malisa T., Yu, Krystle K. Q., Luedemann, Corinne, Suscovich, Todd J., Grace, Patricia S., Cain, Adam, Yu, Wen Han, McKitrick, Tanya R., Lauffenburger, Douglas, Cummings, Richard D., Mayanja-Kizza, Harriet, Hawn, Thomas R., Boom, W. Henry, Stein, Catherine M., Fortune, Sarah M., Seshadri, Chetan, Alter, Galit

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Sex differences in immune responses that underlie COVID-19 disease outcomes von Takahashi, Takehiro, Ellingson, Mallory K., Wong, Patrick, Israelow, Benjamin, Lucas, Carolina, Klein, Jon, Silva, Julio, Mao, Tianyang, Oh, Ji Eun, Tokuyama, Maria, Lu, Peiwen, Venkataraman, Arvind, Park, Annsea, Liu, Feimei, Meir, Amit, Sun, Jonathan, Wang, Eric Y., Casanovas-Massana, Arnau, Wyllie, Anne L., Vogels, Chantal B. F., Earnest, Rebecca, Lapidus, Sarah, Ott, Isabel M., Moore, Adam J., Shaw, Albert, Fournier, John B., Odio, Camila D., Farhadian, Shelli, Dela Cruz, Charles, Grubaugh, Nathan D., Schulz, Wade L., Ring, Aaron M., Ko, Albert I., Omer, Saad B., Iwasaki, Akiko

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Longitudinal analyses reveal immunological misfiring in severe COVID-19 von Lucas, Carolina, Wong, Patrick, Klein, Jon, Castro, Tiago B. R., Silva, Julio, Sundaram, Maria, Ellingson, Mallory K., Mao, Tianyang, Oh, Ji Eun, Israelow, Benjamin, Takahashi, Takehiro, Tokuyama, Maria, Lu, Peiwen, Venkataraman, Arvind, Park, Annsea, Mohanty, Subhasis, Wang, Haowei, Wyllie, Anne L., Vogels, Chantal B. F., Earnest, Rebecca, Lapidus, Sarah, Ott, Isabel M., Moore, Adam J., Muenker, M. Catherine, Fournier, John B., Campbell, Melissa, Odio, Camila D., Casanovas-Massana, Arnau, Herbst, Roy, Shaw, Albert C., Medzhitov, Ruslan, Schulz, Wade L., Grubaugh, Nathan D., Dela Cruz, Charles, Farhadian, Shelli, Ko, Albert I., Omer, Saad B., Iwasaki, Akiko

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fMRI study of olfactory processing in mice under three anesthesia protocols: Insight into the effect of ketamine on olfactory processing von Zhao, Fuqiang, Meng, Xiangjun, Lu, Sherry, Hyde, Lynn A., Kennedy, Matthew E., Houghton, Andrea K., Evelhoch, Jeffrey L., Hines, Catherine D.G.

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Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4.4 million participants von Zhou, Bin, Stevens, Gretchen A, Bjerregaard, Peter, Onat, Altan, Aekplakorn, Wichai, Agyemang, Charles, Ahmadvand, Alireza, Alkerwi, Ala'a, Anjana, Ranjit Mohan, Balakrishna, Nagalla, Bandosz, Piotr, Batieha, Anwar M, Bovet, Pascal, Breckenkamp, Juergen, Brewster, Lizzy M, Bruno, Graziella, Cåndido, Ana Paula C, Capuano, Vincenzo, Castetbon, Katia, Cheng, Ching-Yu, Chetrit, Angela, Cooper, Rachel, Costanzo, Simona, Cottel, Dominique, Dallongeville, Jean, Deepa, Mohan, Dehghan, Abbas, El Ati, Jalila, Elosua, Roberto, Erem, Cihangir, Farzadfar, Farshad, Felix-Redondo, Francisco J, Ferreccio, Catterina, Föger, Bernhard, Forslund, Ann-Sofie, Furusawa, Takuro, Rivas, Juan P Gonzalez, Gorbea, Mariano Bonet, Guimaraes, Andre L, Hambleton, Ian R, Hu, Yang, Ibrahim, M Mohsen, Iwasaki, Masanori, Kengne, Andre P, Kersting, Mathilde, Korrovits, Paul, Kratzer, Wolfgang, Kujala, Urho M, Lachat, Carl, Lappas, Georg, Lima-Costa, M Fernanda, Lin, Hsien-Ho, Lin, Xu, Lundqvist, Annamari, Maggi, Stefania, Rao, Kodavanti Mallikharjuna, Menezes, Ana Maria B, Mi, Jie, Miquel, Juan Francisco, Møller, Niels C, Morgan, Karen, Nang, Ei Ei K, Nangia, Vinay B, Ndiaye, Ndeye Coumba, Ninomiya, Toshiharu, Noto, Davide, Ochoa-Aviles, Angelica M, Oh, Kyungwon, Osmond, Clive, Otero, Johanna A, Owusu-Dabo, Ellis, Peixoto, Sergio Viana, Peykari, Niloofar, Rathmann, Wolfgang, Redon, Josep, Robitaille, Cynthia, Rodriguez-Villamizar, Laura A, Rubinstein, Adolfo, Horimoto, Andrea RV Russo, Simon, Mary, Slowikowska-Hilczer, Jolanta, Söderberg, Stefan, Stathopoulou, Maria G, Stronks, Karien, Suriyawongpaisal, Paibul, Tarqui-Mamani, Carolina B, Thijs, Lutgarde, Tolonen, Hanna K, Tolstrup, Janne S, Torrent, Maties, Turley, Maria L, Ukoli, Flora AM, Veronesi, Giovanni, Verstraeten, Roosmarijn, Wade, Alisha N, Wang, Ya Xing, Weerasekera, Deepa, Widhalm, Kurt, Wong, Tien Yin, Zargar, Abdul Hamid

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Circuits between infected macrophages and T cells in SARS-CoV-2 pneumonia von Grant, Rogan A., Morales-Nebreda, Luisa, Markov, Nikolay S., Swaminathan, Suchitra, Querrey, Melissa, Guzman, Estefany R., Abbott, Darryl A., Donnelly, Helen K., Donayre, Alvaro, Goldberg, Isaac A., Klug, Zasu M., Borkowski, Nicole, Lu, Ziyan, Kihshen, Hermon, Politanska, Yuliya, Sichizya, Lango, Kang, Mengjia, Shilatifard, Ali, Qi, Chao, Lomasney, Jon W., Argento, A. Christine, Kruser, Jacqueline M., Malsin, Elizabeth S., Pickens, Chiagozie O., Smith, Sean B., Walter, James M., Pawlowski, Anna E., Schneider, Daniel, Nannapaneni, Prasanth, Abdala-Valencia, Hiam, Bharat, Ankit, Gottardi, Cara J., Budinger, G. R. Scott, Misharin, Alexander V., Singer, Benjamin D., Wunderink, Richard G.

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The multicopper ferroxidase hephaestin enhances intestinal iron absorption in mice von Fuqua, Brie K, Lu, Yan, Darshan, Deepak, Frazer, David M, Wilkins, Sarah J, Wolkow, Natalie, Bell, Austin G, Hsu, JoAnn, Yu, Catherine C, Chen, Huijun, Dunaief, Joshua L, Anderson, Gregory J, Vulpe, Chris D

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FungalTraits: a user-friendly traits database of fungi and fungus-like stramenopiles von Põlme, Sergei, Clemmensen, Karina Engelbrecht, Kjøller, Rasmus, Bates, Scott T., Baldrian, Petr, Frøslev, Tobias Guldberg, Adojaan, Kristjan, Vizzini, Alfredo, Suija, Ave, Pfister, Donald, Baral, Hans-Otto, Järv, Helle, Madrid, Hugo, Nordén, Jenni, Liu, Jian-Kui, Pawlowska, Julia, Põldmaa, Kadri, Pärtel, Kadri, Runnel, Kadri, Hansen, Karen, Larsson, Karl-Henrik, Hyde, Kevin David, Smith, Matthew E., Toome-Heller, Merje, Wijayawardene, Nalin N., Menolli, Nelson, Reynolds, Nicole K., Drenkhan, Rein, Maharachchikumbura, Sajeewa S. N., Gibertoni, Tatiana B., Læssøe, Thomas, Davis, William, Tokarev, Yuri, Corrales, Adriana, Agan, Ahto, Machado, Alexandre Reis, Detheridge, Andrew, de Meiras-Ottoni, Angelina, Verbeken, Annemieke, Dutta, Arun Kumar, Cui, Bao-Kai, Pradeep, C. K., Stanton, Daniel, Gohar, Daniyal, Wanasinghe, Dhanushka N., Lumbsch, Thorsten H., Grossart, Hans-Peter, Masigol, Hossein, Timling, Ina, Hiiesalu, Inga, Oja, Jane, Kupagme, John Y., Ilves, Kai, Loit, Kaire, Adamson, Kalev, Nara, Kazuhide, Küngas, Kati, Rojas-Jimenez, Keilor, Bitenieks, Krišs, Irinyi, Laszlo, Soonvald, Liina, Wagner, Lysett, Öpik, Maarja, Mujica, María Isabel, Metsoja, Martin, Ryberg, Martin, Vasar, Martti, Murata, Masao, Nelsen, Matthew P., Samarakoon, Milan C., Doilom, Mingkwan, Bahram, Mohammad, Hagh-Doust, Niloufar, Dulya, Olesya, Johnston, Peter, Kohout, Petr, Chen, Qian, Tian, Qing, Nandi, Rajasree, Amiri, Rasekh, Gielen, Robin, Phookamsak, Rungtiwa, Jayawardena, Ruvishika S., Rahimlou, Saleh, Karunarathna, Samantha C., Tibpromma, Saowaluck, Brown, Shawn P., Sepp, Siim-Kaarel, Mundra, Sunil, Vahter, Tanel, Netherway, Tarquin, Yang, Teng, May, Tom, Coimbra, Victor Rafael Matos, de Oliveira, Virton Rodrigo Targino, Lu, Yongzhong, Matsuda, Yosuke, Miyamoto, Yumiko, Kõljalg, Urmas, Tedersoo, Leho

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Transitional B Cells in Early Human B Cell Development - Time to Revisit the Paradigm? von Martin, Victoria G, Wu, Yu-Chang Bryan, Townsend, Catherine L, Lu, Grace H C, O'Hare, Joselli Silva, Mozeika, Alexander, Coolen, Anthonius C C, Kipling, David, Fraternali, Franca, Dunn-Walters, Deborah K

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InterPro in 2017-beyond protein family and domain annotations von Finn, Robert D, Attwood, Teresa K, Babbitt, Patricia C, Bateman, Alex, Bork, Peer, Bridge, Alan J, Chang, Hsin-Yu, Dosztányi, Zsuzsanna, El-Gebali, Sara, Fraser, Matthew, Gough, Julian, Haft, David, Holliday, Gemma L, Huang, Hongzhan, Huang, Xiaosong, Letunic, Ivica, Lopez, Rodrigo, Lu, Shennan, Marchler-Bauer, Aron, Mi, Huaiyu, Mistry, Jaina, Natale, Darren A, Necci, Marco, Nuka, Gift, Orengo, Christine A, Park, Youngmi, Pesseat, Sebastien, Piovesan, Damiano, Potter, Simon C, Rawlings, Neil D, Redaschi, Nicole, Richardson, Lorna, Rivoire, Catherine, Sangrador-Vegas, Amaia, Sigrist, Christian, Sillitoe, Ian, Smithers, Ben, Squizzato, Silvano, Sutton, Granger, Thanki, Narmada, Thomas, Paul D, Tosatto, Silvio C E, Wu, Cathy H, Xenarios, Ioannis, Yeh, Lai-Su, Young, Siew-Yit, Mitchell, Alex L

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Transformation of the education of health professionals in China: progress and challenges von Hou, Jianlin, PhD, Michaud, Catherine, MD, Li, Zhihui, MS, Dong, Zhe, Prof, Sun, Baozhi, Prof, Zhang, Junhua, PhD, Cao, Depin, Prof, Wan, Xuehong, PhD, Zeng, Cheng, Prof, Wei, Bo, Prof, Tao, Lijian, Prof, Li, Xiaosong, Prof, Wang, Weimin, Prof, Lu, Yingqing, Prof, Xia, Xiulong, Prof, Guo, Guifang, Prof, Zhang, Zhiyong, Prof, Cao, Yunfei, MD, Guan, Yuanzhi, MM, Meng, Qingyue, Prof, Wang, Qing, MM, Zhao, Yuhong, Prof, Liu, Huaping, Prof, Lin, Huiqing, PhD, Ke, Yang, Prof, Chen, Lincoln, MD

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Revised diagnostic criteria for neurofibromatosis type 1 and Legius syndrome: an international consensus recommendation von Legius, Eric, Messiaen, Ludwine, Wolkenstein, Pierre, Pancza, Patrice, Avery, Robert A., Berman, Yemima, Blakeley, Jaishri, Babovic-Vuksanovic, Dusica, Cunha, Karin Soares, Ferner, Rosalie, Fisher, Michael J., Friedman, Jan M., Gutmann, David H., Kehrer-Sawatzki, Hildegard, Korf, Bruce R., Mautner, Victor-Felix, Peltonen, Sirkku, Rauen, Katherine A., Riccardi, Vincent, Schorry, Elizabeth, Stemmer-Rachamimov, Anat, Stevenson, David A., Tadini, Gianluca, Ullrich, Nicole J., Viskochil, David, Wimmer, Katharina, Yohay, Kaleb, Gomes, Alicia, Jordan, Justin T., Mautner, Victor, Merker, Vanessa L., Smith, Miriam J., Stevenson, David, Anten, Monique, Aylsworth, Arthur, Baralle, Diana, Barbarot, Sebastien, Barker, Fred, Ben-Shachar, Shay, Bergner, Amanda, Bessis, Didier, Blanco, Ignacio, Cassiman, Catherine, Ciavarelli, Patricia, Clementi, Maurizio, Frébourg, Thierry, Giovannini, Marco, Halliday, Dorothy, Hammond, Chris, Hanemann, C.O., Hanson, Helen, Heiberg, Arvid, Joly, Pascal, Kalamarides, Michel, Karajannis, Matthias, Kroshinsky, Daniela, Larralde, Margarita, Lázaro, Conxi, Le, Lu, Link, Michael, Listernick, Robert, MacCollin, Mia, Mallucci, Conor, Moertel, Christopher, Mueller, Amy, Ngeow, Joanne, Oostenbrink, Rianne, Packer, Roger, Papi, Laura, Parry, Allyson, Peltonen, Juha, Pichard, Dominique, Poppe, Bruce, Rezende, Nilton, Rodrigues, Luiz Oswaldo, Rosser, Tena, Ruggieri, Martino, Serra, Eduard, Steinke-Lange, Verena, Stivaros, Stavros Michael, Taylor, Amy, Toelen, Jaan, Tonsgard, James, Trevisson, Eva, Upadhyaya, Meena, Varan, Ali, Wilson, Meredith, Wu, Hao, Zadeh, Gelareh, Huson, Susan M., Evans, D. Gareth, Plotkin, Scott R.

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Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer von Kim, Jaegil, Bellmunt, Joaquim, Cherniack, Andrew D., Hinoue, Toshinori, Hoadley, Katherine A., Gibb, Ewan A., Shukla, Sachet A., Sanchez-Vega, Francisco, Reuter, Victor E., Sadeghi, Sara, Pedamallu, Chandra Sekhar, Lu, Yiling, Klimczak, Leszek J., Zhang, Jiexin, Choo, Caleb, Leraas, Kristen M., Lichtenberg, Tara M., Schultz, Nicholaus, Getz, Gad, Mills, Gordon B., Al-Ahmadie, Hikmat, Alexopoulou, Iakovina, Ally, Adrian, Beaver, Allison, Bellmunt, Joaquim, Boice, Lori, Bootwalla, Moiz S., Bowen, Jay, Brooks, Denise, Broom, Bradley M., Bshara, Wiam, Bullman, Susan, Burks, Eric, Carvalho, Benilton S., Carvalho, Andre L., Castro, Mauro A.A., Chagas, Vinicius S., Cherniack, Andrew D., Cortessis, Victoria K., Czerniak, Bogdan A., Daneshmand, Siamak, Dhalla, Noreen, Egea, Sophie C., Engel, Jay, Felau, Ina, Gastier-Foster, Julie M., Getz, Gad, Gordenin, Dmitry A., Hansel, Donna E., Harr, Jodi, Hartmann, Arndt, Hinoue, Toshinori, Jones, Steven J.M., Kahnoski, Richard J., Kasaian, Katayoon, Lai, Phillip H., Lane, Brian R., Liu, Jia, Lolla, Laxmi, Lotan, Yair, Lu, Yiling, Lucchesi, Fabiano R., Mallery, David, Marra, Marco A., Mills, Gordon B., Mungall, Karen L., Ojesina, Akinyemi I., Parekh, Dipen J., Sekhar Pedamallu, Chandra, Pihl, Todd, Rathmell, W. Kimryn, Robertson, A. Gordon, Sadeghi, Sara, Saller, Charles, Salner, Andrew, Sanchez-Vega, Francisco, Scapulatempo-Neto, Cristovam, Schuckman, Anne K., Shukla, Sachet A., Simko, Jeff, Sipahimalani, Payal, Sorcini, Andrea, Stoehr, Robert, Su, Xiaoping, Tarnuzzer, Roy, Thiessen, Nina, Thorne, Leigh, Tse, Kane, Wach, Sven, Wang, Zhining, Weinstein, John N., Wise, Lisa, Wong, Tina, Wu, Ye, Zach, Leigh Anne, Zenklusen, Jean C., Zhang, Jiashan (Julia), Zhang, Jiexin, Zwarthoff, Ellen C., Weinstein, John N.

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